IL84658A - Esters of 3-hydroxy-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing the same - Google Patents

Esters of 3-hydroxy-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing the same

Info

Publication number
IL84658A
IL84658A IL84658A IL8465887A IL84658A IL 84658 A IL84658 A IL 84658A IL 84658 A IL84658 A IL 84658A IL 8465887 A IL8465887 A IL 8465887A IL 84658 A IL84658 A IL 84658A
Authority
IL
Israel
Prior art keywords
alkyl
pyrrolidinyl
substituted
piperidyl
piperazinyl
Prior art date
Application number
IL84658A
Other languages
English (en)
Other versions
IL84658A0 (en
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of IL84658A0 publication Critical patent/IL84658A0/xx
Publication of IL84658A publication Critical patent/IL84658A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Rolls And Other Rotary Bodies (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL84658A 1986-12-02 1987-11-29 Esters of 3-hydroxy-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing the same IL84658A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8616796A FR2607504B1 (fr) 1986-12-02 1986-12-02 Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
IL84658A0 IL84658A0 (en) 1988-04-29
IL84658A true IL84658A (en) 1992-01-15

Family

ID=9341443

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84658A IL84658A (en) 1986-12-02 1987-11-29 Esters of 3-hydroxy-2-heteroaryl substituted bicyclic pyrrol-1-one derivatives,their preparation and pharmaceutical compositions containing the same

Country Status (23)

Country Link
EP (1) EP0271404B1 (no)
JP (1) JPS63154682A (no)
KR (1) KR880007517A (no)
AT (1) ATE66219T1 (no)
AU (1) AU594215B2 (no)
CA (1) CA1298295C (no)
DE (1) DE3772172D1 (no)
DK (1) DK169969B1 (no)
ES (1) ES2038687T3 (no)
FI (1) FI84723C (no)
FR (1) FR2607504B1 (no)
GR (1) GR3002490T3 (no)
HU (1) HU197573B (no)
IE (1) IE61089B1 (no)
IL (1) IL84658A (no)
MA (1) MA21118A1 (no)
MX (1) MX9558A (no)
NO (1) NO166037C (no)
NZ (1) NZ222752A (no)
OA (1) OA08696A (no)
PT (1) PT86261B (no)
SU (3) SU1616515A3 (no)
ZA (1) ZA879001B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2607503B1 (fr) * 1986-12-02 1989-02-24 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
CZ309617B6 (cs) * 2019-04-05 2023-05-24 Ústav organické chemie a biochemie AV ČR, v. v. i 3α5ß-Neuroaktivní steroidy pro léčbu epilepsie a záchvatových onemocnění

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2101081B1 (no) * 1970-08-19 1974-01-11 Rhone Poulenc Sa
OA04285A (fr) * 1972-01-07 1979-12-31 Rhone Poulenc Sa Nouveaux dérivés de la pyrrolo (3,4-b) pyrazine et leur préparation.
AR207555A1 (es) * 1972-12-04 1976-10-15 Procedimiento para preparar aril-6-piperazinocarboniloxi-5 oxo-7 tetrahidro-2,3,6,7 ditiino(1,4)(2,3-c)pirroles
AR208414A1 (es) * 1974-11-07 1976-12-27 Rhone Poulenc Ind Procedimiento para obtener nuevos derivados de la((acil-4piperazinil-1)carboniloxi-5 pirrolinona-2)
ZA756953B (en) * 1974-11-07 1976-10-27 Rhone Poulenc Ind 1,4-oxathiino(2,3-c)pyrrole derivatives
US4590189A (en) * 1982-04-02 1986-05-20 Takeda Chemical Industries, Ltd. Condensed pyrrolinone derivatives, their production and use
FR2559484B2 (fr) * 1983-07-06 1986-09-26 Provesan Sa Nouveau derive 7-(pyrrol-1-yl) de l'acide 1-ethyl-1,4-dihydro-4-oxo-(1,8-naphtyridin)-3-carboxylique, sa preparation et son application en tant que medicament
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
JPS6169773A (ja) * 1984-09-14 1986-04-10 Takeda Chem Ind Ltd イソインドリノン誘導体
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
FR2607503B1 (fr) * 1986-12-02 1989-02-24 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
ES2038687T3 (es) 1993-08-01
HUT46007A (en) 1988-09-28
NO166037B (no) 1991-02-11
FI84723B (fi) 1991-09-30
AU594215B2 (en) 1990-03-01
AU8193687A (en) 1988-06-02
NO875012L (no) 1988-06-03
FI84723C (fi) 1992-01-10
IE873252L (en) 1988-06-02
SU1685264A3 (ru) 1991-10-15
ZA879001B (en) 1988-06-01
IE61089B1 (en) 1994-09-21
KR880007517A (ko) 1988-08-27
SU1657056A3 (ru) 1991-06-15
PT86261A (fr) 1988-01-01
NO875012D0 (no) 1987-12-01
PT86261B (pt) 1990-11-07
DK630487D0 (da) 1987-12-01
OA08696A (fr) 1989-03-31
MX9558A (es) 1993-11-01
GR3002490T3 (en) 1992-12-30
JPS63154682A (ja) 1988-06-27
FI875299A0 (fi) 1987-12-01
FI875299A (fi) 1988-06-03
EP0271404A3 (en) 1989-04-05
IL84658A0 (en) 1988-04-29
DK169969B1 (da) 1995-04-18
NZ222752A (en) 1989-10-27
DE3772172D1 (de) 1991-09-19
CA1298295C (fr) 1992-03-31
DK630487A (da) 1988-06-03
ATE66219T1 (de) 1991-08-15
EP0271404B1 (fr) 1991-08-14
FR2607504B1 (fr) 1989-01-27
EP0271404A2 (fr) 1988-06-15
FR2607504A1 (fr) 1988-06-03
HU197573B (en) 1989-04-28
SU1616515A3 (ru) 1990-12-23
NO166037C (no) 1991-05-22
MA21118A1 (fr) 1988-07-01

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