IL84051A0 - 7-((meta-substituted)phenylglycine)1-carba-1-dethiacephalosporins - Google Patents
7-((meta-substituted)phenylglycine)1-carba-1-dethiacephalosporinsInfo
- Publication number
- IL84051A0 IL84051A0 IL84051A IL8405187A IL84051A0 IL 84051 A0 IL84051 A0 IL 84051A0 IL 84051 A IL84051 A IL 84051A IL 8405187 A IL8405187 A IL 8405187A IL 84051 A0 IL84051 A0 IL 84051A0
- Authority
- IL
- Israel
- Prior art keywords
- dethiacephalosporins
- carba
- phenylglycine
- meta
- substituted
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91517386A | 1986-10-03 | 1986-10-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL84051A0 true IL84051A0 (en) | 1988-03-31 |
Family
ID=25435354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL84051A IL84051A0 (en) | 1986-10-03 | 1987-10-01 | 7-((meta-substituted)phenylglycine)1-carba-1-dethiacephalosporins |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0266896B1 (enExample) |
| JP (1) | JPS6396186A (enExample) |
| KR (1) | KR880005125A (enExample) |
| CN (1) | CN87107149A (enExample) |
| AT (2) | ATE79119T1 (enExample) |
| BG (1) | BG47034A3 (enExample) |
| DE (1) | DE3780909T2 (enExample) |
| DK (1) | DK518487A (enExample) |
| FI (1) | FI874311L (enExample) |
| GR (1) | GR3005920T3 (enExample) |
| HU (1) | HU200179B (enExample) |
| IE (1) | IE872646L (enExample) |
| IL (1) | IL84051A0 (enExample) |
| NZ (1) | NZ222015A (enExample) |
| PL (1) | PL151703B1 (enExample) |
| PT (1) | PT85850B (enExample) |
| ZA (1) | ZA877398B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0327364A1 (en) * | 1988-02-05 | 1989-08-09 | Eli Lilly And Company | Crystalline beta-lactam solvate |
| US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| HU230253B1 (hu) | 2001-01-26 | 2015-11-30 | Merck Sharp & Dohme Corp | Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére |
| ATE331512T1 (de) | 2001-01-26 | 2006-07-15 | Schering Corp | Verwendung azetidinone-substituierter verbindungen zur behandlung der sitosterolhämie |
| JP4145663B2 (ja) | 2001-03-28 | 2008-09-03 | シェーリング コーポレイション | アゼチジノン中間体化合物のエナンチオ選択性合成 |
| EP1429756B1 (en) | 2001-09-21 | 2006-11-22 | Schering Corporation | Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors |
| US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| WO2004037163A2 (en) * | 2002-05-14 | 2004-05-06 | Northwestern University | STERICALLY-AWKWARD β-LACTAMASE INHIBITORS |
| JP2006508189A (ja) | 2002-11-06 | 2006-03-09 | シェーリング コーポレイション | 自己免疫障害の処置のためのコレステロール吸収インヒビター |
| US7192944B2 (en) | 2003-03-07 | 2007-03-20 | Schering Corp. | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| JP4589919B2 (ja) | 2003-03-07 | 2010-12-01 | シェーリング コーポレイション | 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用 |
| DE602004016123D1 (de) | 2003-03-07 | 2008-10-09 | Schering Corp | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| CN102144992B (zh) * | 2011-03-10 | 2013-04-10 | 浙江大学 | 苯基甘氨酸衍生物制备对金黄色葡萄球菌有抑菌和杀菌活性的抗菌剂的用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3697515A (en) * | 1963-02-18 | 1972-10-10 | Ciba Geigy Corp | Process for splitting the 7-n-acyl group from cephalosporin compounds |
| JPS5672698A (en) * | 1979-11-14 | 1981-06-16 | Kyowa Hakko Kogyo Co Ltd | Preparation of optically active cephalosporin analogue |
| NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
| NO155547C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling. |
| JPS60174787A (ja) * | 1984-02-21 | 1985-09-09 | Kyowa Hakko Kogyo Co Ltd | ３位置換カルバセフエム化合物 |
| US4673737A (en) * | 1985-08-02 | 1987-06-16 | Harvard University | 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof |
-
1987
- 1987-10-01 IL IL84051A patent/IL84051A0/xx unknown
- 1987-10-01 FI FI874311A patent/FI874311L/fi not_active IP Right Cessation
- 1987-10-01 ZA ZA877398A patent/ZA877398B/xx unknown
- 1987-10-01 AT AT87308713T patent/ATE79119T1/de not_active IP Right Cessation
- 1987-10-01 PT PT85850A patent/PT85850B/pt unknown
- 1987-10-01 CN CN198787107149A patent/CN87107149A/zh active Pending
- 1987-10-01 EP EP87308713A patent/EP0266896B1/en not_active Expired - Lifetime
- 1987-10-01 DE DE8787308713T patent/DE3780909T2/de not_active Expired - Fee Related
- 1987-10-01 NZ NZ222015A patent/NZ222015A/xx unknown
- 1987-10-02 DK DK518487A patent/DK518487A/da not_active Application Discontinuation
- 1987-10-02 IE IE872646A patent/IE872646L/xx unknown
- 1987-10-02 HU HU874452A patent/HU200179B/hu not_active IP Right Cessation
- 1987-10-02 JP JP62250552A patent/JPS6396186A/ja active Pending
- 1987-10-02 KR KR870011038A patent/KR880005125A/ko not_active Withdrawn
- 1987-10-02 PL PL1987268034A patent/PL151703B1/pl unknown
- 1987-10-02 BG BG081345A patent/BG47034A3/xx unknown
- 1987-10-08 AT AT0257587A patent/AT388377B/de active
-
1992
- 1992-10-08 GR GR920402240T patent/GR3005920T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6396186A (ja) | 1988-04-27 |
| EP0266896A1 (en) | 1988-05-11 |
| FI874311A7 (fi) | 1988-04-04 |
| PT85850A (en) | 1987-11-01 |
| ATA257587A (de) | 1988-11-15 |
| AU7926987A (en) | 1988-04-14 |
| PT85850B (en) | 1990-01-12 |
| HUT45053A (en) | 1988-05-30 |
| IE872646L (en) | 1988-04-03 |
| CN87107149A (zh) | 1988-05-18 |
| DE3780909D1 (en) | 1992-09-10 |
| HU200179B (en) | 1990-04-28 |
| ATE79119T1 (de) | 1992-08-15 |
| AT388377B (de) | 1989-06-12 |
| PL268034A1 (en) | 1988-09-01 |
| DE3780909T2 (de) | 1993-03-04 |
| EP0266896B1 (en) | 1992-08-05 |
| GR3005920T3 (enExample) | 1993-06-07 |
| FI874311A0 (fi) | 1987-10-01 |
| PL151703B1 (en) | 1990-09-28 |
| KR880005125A (ko) | 1988-06-28 |
| ZA877398B (en) | 1989-05-30 |
| DK518487A (da) | 1988-04-04 |
| FI874311L (fi) | 1988-04-04 |
| BG47034A3 (bg) | 1990-04-16 |
| NZ222015A (en) | 1989-10-27 |
| AU591811B2 (en) | 1989-12-14 |
| DK518487D0 (da) | 1987-10-02 |
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