GR3005920T3 - - Google Patents

Info

Publication number
GR3005920T3
GR3005920T3 GR920402240T GR920402240T GR3005920T3 GR 3005920 T3 GR3005920 T3 GR 3005920T3 GR 920402240 T GR920402240 T GR 920402240T GR 920402240 T GR920402240 T GR 920402240T GR 3005920 T3 GR3005920 T3 GR 3005920T3
Authority
GR
Greece
Prior art keywords
chem
pharmaceutically
alkyl
compounds
formula
Prior art date
Application number
GR920402240T
Other languages
Greek (el)
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3005920T3 publication Critical patent/GR3005920T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR920402240T 1986-10-03 1992-10-08 GR3005920T3 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91517386A 1986-10-03 1986-10-03

Publications (1)

Publication Number Publication Date
GR3005920T3 true GR3005920T3 (enExample) 1993-06-07

Family

ID=25435354

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920402240T GR3005920T3 (enExample) 1986-10-03 1992-10-08

Country Status (17)

Country Link
EP (1) EP0266896B1 (enExample)
JP (1) JPS6396186A (enExample)
KR (1) KR880005125A (enExample)
CN (1) CN87107149A (enExample)
AT (2) ATE79119T1 (enExample)
BG (1) BG47034A3 (enExample)
DE (1) DE3780909T2 (enExample)
DK (1) DK518487A (enExample)
FI (1) FI874311L (enExample)
GR (1) GR3005920T3 (enExample)
HU (1) HU200179B (enExample)
IE (1) IE872646L (enExample)
IL (1) IL84051A0 (enExample)
NZ (1) NZ222015A (enExample)
PL (1) PL151703B1 (enExample)
PT (1) PT85850B (enExample)
ZA (1) ZA877398B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0327364A1 (en) * 1988-02-05 1989-08-09 Eli Lilly And Company Crystalline beta-lactam solvate
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
IL156445A0 (en) 2001-01-26 2004-01-04 Schering Corp Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
KR20070120617A (ko) 2001-01-26 2007-12-24 쉐링 코포레이션 치환된 아제티딘온 화합물을 포함하는 약제학적 조성물
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
BRPI0208384B1 (pt) 2001-03-28 2016-05-31 Merck Sharp & Dohme síntese enantiosseletiva de compostos intermediários de azetidinona
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
EP1429756B1 (en) 2001-09-21 2006-11-22 Schering Corporation Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030236243A1 (en) * 2002-05-14 2003-12-25 Shoichet Brian K. Sterically-awkward beta-lactamase inhibitors
CA2504916A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
WO2004081002A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
DE602004018617D1 (de) 2003-03-07 2009-02-05 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
WO2004081004A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
CN102144992B (zh) * 2011-03-10 2013-04-10 浙江大学 苯基甘氨酸衍生物制备对金黄色葡萄球菌有抑菌和杀菌活性的抗菌剂的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697515A (en) * 1963-02-18 1972-10-10 Ciba Geigy Corp Process for splitting the 7-n-acyl group from cephalosporin compounds
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
NO155547C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling.
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd 3位置換カルバセフエム化合物
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof

Also Published As

Publication number Publication date
ATE79119T1 (de) 1992-08-15
BG47034A3 (bg) 1990-04-16
AT388377B (de) 1989-06-12
PT85850B (en) 1990-01-12
PL268034A1 (en) 1988-09-01
HUT45053A (en) 1988-05-30
DE3780909T2 (de) 1993-03-04
PL151703B1 (en) 1990-09-28
KR880005125A (ko) 1988-06-28
AU591811B2 (en) 1989-12-14
DE3780909D1 (en) 1992-09-10
EP0266896A1 (en) 1988-05-11
JPS6396186A (ja) 1988-04-27
FI874311A0 (fi) 1987-10-01
DK518487A (da) 1988-04-04
EP0266896B1 (en) 1992-08-05
ZA877398B (en) 1989-05-30
DK518487D0 (da) 1987-10-02
AU7926987A (en) 1988-04-14
IL84051A0 (en) 1988-03-31
CN87107149A (zh) 1988-05-18
FI874311A7 (fi) 1988-04-04
IE872646L (en) 1988-04-03
HU200179B (en) 1990-04-28
FI874311L (fi) 1988-04-04
NZ222015A (en) 1989-10-27
ATA257587A (de) 1988-11-15
PT85850A (en) 1987-11-01

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