ATA257587A - 7-((m-subst.)-phenylglycin)-1-carba-1dethiacephalosporine - Google Patents
7-((m-subst.)-phenylglycin)-1-carba-1dethiacephalosporineInfo
- Publication number
- ATA257587A ATA257587A AT0257587A AT257587A ATA257587A AT A257587 A ATA257587 A AT A257587A AT 0257587 A AT0257587 A AT 0257587A AT 257587 A AT257587 A AT 257587A AT A257587 A ATA257587 A AT A257587A
- Authority
- AT
- Austria
- Prior art keywords
- phenylglycin
- carba
- subst
- chem
- pharmaceutically
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91517386A | 1986-10-03 | 1986-10-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA257587A true ATA257587A (de) | 1988-11-15 |
| AT388377B AT388377B (de) | 1989-06-12 |
Family
ID=25435354
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87308713T ATE79119T1 (de) | 1986-10-03 | 1987-10-01 | 7-((meta-substituiert)-phenylglycin>-1-carba-1dethia-cephalosporine. |
| AT0257587A AT388377B (de) | 1986-10-03 | 1987-10-08 | 7-((m-subst.)-phenylglycin)-1-carba-1dethiacephalosporine |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87308713T ATE79119T1 (de) | 1986-10-03 | 1987-10-01 | 7-((meta-substituiert)-phenylglycin>-1-carba-1dethia-cephalosporine. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0266896B1 (de) |
| JP (1) | JPS6396186A (de) |
| KR (1) | KR880005125A (de) |
| CN (1) | CN87107149A (de) |
| AT (2) | ATE79119T1 (de) |
| BG (1) | BG47034A3 (de) |
| DE (1) | DE3780909T2 (de) |
| DK (1) | DK518487A (de) |
| FI (1) | FI874311A7 (de) |
| GR (1) | GR3005920T3 (de) |
| HU (1) | HU200179B (de) |
| IE (1) | IE872646L (de) |
| IL (1) | IL84051A0 (de) |
| NZ (1) | NZ222015A (de) |
| PL (1) | PL151703B1 (de) |
| PT (1) | PT85850B (de) |
| ZA (1) | ZA877398B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ227842A (en) * | 1988-02-05 | 1990-12-21 | Lilly Co Eli | Crystalline 2.5-hydrate form of a beta-lactam |
| US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| AU2002247019C1 (en) | 2001-01-26 | 2017-05-11 | Organon Llc | Combinations of peroxisome proliferator-activated receptor (PPAR) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications |
| RU2756946C2 (ru) | 2001-01-26 | 2021-10-07 | Мерк Шарп И Доум Корп. | Применение замещенных азетидинонов для лечения ситостеролемии |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| PL205952B1 (pl) | 2001-03-28 | 2010-06-30 | Schering Corp | Sposób wytwarzania związków oksazolidynonowych |
| DE60216300T2 (de) | 2001-09-21 | 2007-06-28 | Schering Corp. | Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption |
| US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| US20030236243A1 (en) * | 2002-05-14 | 2003-12-25 | Shoichet Brian K. | Sterically-awkward beta-lactamase inhibitors |
| CA2504878A1 (en) | 2002-11-06 | 2004-05-27 | Schering Corporation | Cholesterol absorption inhibitors for the treatment of demyelination |
| MXPA05009502A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| MXPA05009501A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| EP1601668B1 (de) | 2003-03-07 | 2008-08-27 | Schering Corporation | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| CN102144992B (zh) * | 2011-03-10 | 2013-04-10 | 浙江大学 | 苯基甘氨酸衍生物制备对金黄色葡萄球菌有抑菌和杀菌活性的抗菌剂的用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3697515A (en) * | 1963-02-18 | 1972-10-10 | Ciba Geigy Corp | Process for splitting the 7-n-acyl group from cephalosporin compounds |
| NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
| JPS5672698A (en) * | 1979-11-14 | 1981-06-16 | Kyowa Hakko Kogyo Co Ltd | Preparation of optically active cephalosporin analogue |
| NO155547C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling. |
| JPS60174787A (ja) * | 1984-02-21 | 1985-09-09 | Kyowa Hakko Kogyo Co Ltd | ３位置換カルバセフエム化合物 |
| US4673737A (en) * | 1985-08-02 | 1987-06-16 | Harvard University | 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof |
-
1987
- 1987-10-01 CN CN198787107149A patent/CN87107149A/zh active Pending
- 1987-10-01 FI FI874311A patent/FI874311A7/fi not_active IP Right Cessation
- 1987-10-01 IL IL84051A patent/IL84051A0/xx unknown
- 1987-10-01 EP EP87308713A patent/EP0266896B1/de not_active Expired - Lifetime
- 1987-10-01 DE DE8787308713T patent/DE3780909T2/de not_active Expired - Fee Related
- 1987-10-01 PT PT85850A patent/PT85850B/pt unknown
- 1987-10-01 NZ NZ222015A patent/NZ222015A/xx unknown
- 1987-10-01 ZA ZA877398A patent/ZA877398B/xx unknown
- 1987-10-01 AT AT87308713T patent/ATE79119T1/de not_active IP Right Cessation
- 1987-10-02 IE IE872646A patent/IE872646L/xx unknown
- 1987-10-02 KR KR870011038A patent/KR880005125A/ko not_active Withdrawn
- 1987-10-02 JP JP62250552A patent/JPS6396186A/ja active Pending
- 1987-10-02 BG BG081345A patent/BG47034A3/xx unknown
- 1987-10-02 PL PL1987268034A patent/PL151703B1/pl unknown
- 1987-10-02 DK DK518487A patent/DK518487A/da not_active Application Discontinuation
- 1987-10-02 HU HU874452A patent/HU200179B/hu not_active IP Right Cessation
- 1987-10-08 AT AT0257587A patent/AT388377B/de active
-
1992
- 1992-10-08 GR GR920402240T patent/GR3005920T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3780909D1 (en) | 1992-09-10 |
| EP0266896A1 (de) | 1988-05-11 |
| FI874311A0 (fi) | 1987-10-01 |
| FI874311L (fi) | 1988-04-04 |
| KR880005125A (ko) | 1988-06-28 |
| AU7926987A (en) | 1988-04-14 |
| PL151703B1 (en) | 1990-09-28 |
| AT388377B (de) | 1989-06-12 |
| JPS6396186A (ja) | 1988-04-27 |
| AU591811B2 (en) | 1989-12-14 |
| DK518487A (da) | 1988-04-04 |
| PL268034A1 (en) | 1988-09-01 |
| FI874311A7 (fi) | 1988-04-04 |
| BG47034A3 (bg) | 1990-04-16 |
| DE3780909T2 (de) | 1993-03-04 |
| PT85850A (en) | 1987-11-01 |
| IL84051A0 (en) | 1988-03-31 |
| DK518487D0 (da) | 1987-10-02 |
| HUT45053A (en) | 1988-05-30 |
| CN87107149A (zh) | 1988-05-18 |
| HU200179B (en) | 1990-04-28 |
| IE872646L (en) | 1988-04-03 |
| GR3005920T3 (de) | 1993-06-07 |
| ZA877398B (en) | 1989-05-30 |
| NZ222015A (en) | 1989-10-27 |
| ATE79119T1 (de) | 1992-08-15 |
| PT85850B (en) | 1990-01-12 |
| EP0266896B1 (de) | 1992-08-05 |
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