IL79556A - Pharmaceutical preparations containing internal salts of naphthyridine and related compounds, their salts, solvates, hydrates and esters, new compounds of this type and their preparation - Google Patents

Pharmaceutical preparations containing internal salts of naphthyridine and related compounds, their salts, solvates, hydrates and esters, new compounds of this type and their preparation

Info

Publication number
IL79556A
IL79556A IL7955686A IL7955686A IL79556A IL 79556 A IL79556 A IL 79556A IL 7955686 A IL7955686 A IL 7955686A IL 7955686 A IL7955686 A IL 7955686A IL 79556 A IL79556 A IL 79556A
Authority
IL
Israel
Prior art keywords
carbon atoms
carbon
group
alkyl
hydroxy
Prior art date
Application number
IL7955686A
Other languages
English (en)
Hebrew (he)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL79556A publication Critical patent/IL79556A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Outer Garments And Coats (AREA)
IL7955686A 1985-07-29 1986-07-29 Pharmaceutical preparations containing internal salts of naphthyridine and related compounds, their salts, solvates, hydrates and esters, new compounds of this type and their preparation IL79556A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/760,196 US4684727A (en) 1985-07-29 1985-07-29 Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

Publications (1)

Publication Number Publication Date
IL79556A true IL79556A (en) 1995-05-26

Family

ID=25058394

Family Applications (1)

Application Number Title Priority Date Filing Date
IL7955686A IL79556A (en) 1985-07-29 1986-07-29 Pharmaceutical preparations containing internal salts of naphthyridine and related compounds, their salts, solvates, hydrates and esters, new compounds of this type and their preparation

Country Status (23)

Country Link
US (4) US4684727A (pt)
EP (1) EP0232328B1 (pt)
JP (1) JPH0794455B2 (pt)
KR (1) KR900003490B1 (pt)
AT (1) ATE74756T1 (pt)
AU (1) AU597587B2 (pt)
CA (1) CA1263654A (pt)
CZ (1) CZ413991A3 (pt)
DE (1) DE3684903D1 (pt)
DK (1) DK157787A (pt)
FI (1) FI871345A (pt)
HU (1) HU201550B (pt)
IE (1) IE59298B1 (pt)
IL (1) IL79556A (pt)
MX (1) MX9203320A (pt)
MY (1) MY101970A (pt)
NO (1) NO166862C (pt)
NZ (1) NZ217016A (pt)
OA (1) OA08501A (pt)
PH (1) PH23887A (pt)
PT (1) PT83080B (pt)
WO (1) WO1987000752A2 (pt)
ZA (1) ZA865631B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
US5045542A (en) * 1986-10-20 1991-09-03 Schering Corporation Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
US5350755A (en) * 1986-12-05 1994-09-27 Schering Corporation Compounds and methods for treating hyperproliferative skin disease
CA1309658C (en) * 1986-12-05 1992-11-03 David J. Blythin Pharmaceutical compositions for treatment of hyperproliferate skin disease
AU632461B2 (en) * 1987-07-22 1993-01-07 Schering Corporation Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
US4897487A (en) * 1988-04-06 1990-01-30 Schering Corporation Process for preparing intermediates for pharmaceutically useful bicyclic compounds
US5180823A (en) * 1988-04-06 1993-01-19 Schering Corporation Processes for preparing bicyclic compounds
US5079360A (en) * 1988-04-06 1992-01-07 Schering Corporation Processes for preparing bicyclic compounds and intermediates thereof
US5341575A (en) * 1989-11-01 1994-08-30 Chisum Finis L Apparatus to gather, display, and/or print vehicle chassis measurement data for accurate repair of collision damaged vehicles
US5412104A (en) * 1990-09-07 1995-05-02 Schering Corporation Ester and alkoxy substituted benzopyrans
US5175151A (en) * 1990-09-07 1992-12-29 Schering Corporation Antiviral compounds and antihypertensive compounds
US5760034A (en) * 1990-11-30 1998-06-02 Schering Corporation Heterocyclic substituted naphthyridinones and methods and compositions employing them
GB9026389D0 (en) * 1990-12-05 1991-01-23 Merck Sharp & Dohme Therapeutic agents
US5179093A (en) * 1991-05-10 1993-01-12 Schering Corporation Quinoline-diones
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
EP1638581A2 (en) 2003-03-31 2006-03-29 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
WO2007092451A2 (en) 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
JP6273200B2 (ja) 2011-07-12 2018-01-31 ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド 脂質含有ｐｓａ組成物、その単離の方法および使用の方法
EP3337321A4 (en) 2015-08-19 2019-07-17 President and Fellows of Harvard College LIPIDED PSA COMPOSITIONS AND METHOD
WO2018014012A1 (en) 2016-07-15 2018-01-18 President And Fellows Of Harvard College Glycolipid compositions and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264602A (en) * 1975-08-15 1981-04-28 Sandoz, Inc. 4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
FR2469962A1 (fr) * 1979-11-21 1981-05-29 Vallourec Procede et dispositif pour la fabrication d'un tube d'acier sans soudure par laminage a chaud sur mandrin
EP0092786B1 (en) * 1982-04-26 1987-01-07 Schering Corporation 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
US4452800A (en) * 1982-04-26 1984-06-05 Schering Corporation Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
US4551463A (en) * 1982-11-03 1985-11-05 Schering Corporation Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
US4628055A (en) * 1982-11-03 1986-12-09 Schering Corporation Method for treating allergic reactions and compositions therefore
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

Also Published As

Publication number Publication date
PH23887A (en) 1989-12-18
HU201550B (en) 1990-11-28
KR870700352A (ko) 1987-12-28
AU597587B2 (en) 1990-06-07
WO1987000752A3 (en) 1987-05-21
FI871345A0 (fi) 1987-03-27
DK157787D0 (da) 1987-03-27
MX9203320A (es) 1992-07-01
CZ413991A3 (en) 1993-01-13
NO166862C (no) 1991-09-11
US4782067A (en) 1988-11-01
WO1987000752A2 (en) 1987-02-12
JPS63500453A (ja) 1988-02-18
ZA865631B (en) 1987-03-25
US4902693A (en) 1990-02-20
CA1263654A (en) 1989-12-05
NZ217016A (en) 1989-11-28
PT83080B (pt) 1989-01-30
NO871311L (no) 1987-03-27
HUT42481A (en) 1987-07-28
MY101970A (en) 1992-02-29
EP0232328B1 (en) 1992-04-15
NO166862B (no) 1991-06-03
PT83080A (en) 1986-08-01
ATE74756T1 (de) 1992-05-15
DE3684903D1 (de) 1992-05-21
FI871345A (fi) 1987-03-27
NO871311D0 (no) 1987-03-27
JPH0794455B2 (ja) 1995-10-11
IE861997L (en) 1987-01-29
AU6147986A (en) 1987-03-05
EP0232328A1 (en) 1987-08-19
US4684727A (en) 1987-08-04
IE59298B1 (en) 1994-02-09
OA08501A (en) 1988-07-29
DK157787A (da) 1987-03-27
US4794116A (en) 1988-12-27
KR900003490B1 (ko) 1990-05-21

Similar Documents

Publication Publication Date Title
EP0232328B1 (en) Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters
AU656859B2 (en) Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent
AU654808B2 (en) Diaromatic substituted anti-aids compounds
US6737424B2 (en) Alpha-substituted pyridazino quinoline compounds
JPH0267282A (ja) 四環式ケトン
JPH06505979A (ja) ベンゾフラン誘導体
EP0115049B1 (en) 1-ethyl-6,8-difluoro-1,4-dihydro-7-(1-imidazolyl)-4-oxoquinoline-3-carboxylic acid derivatives, process for preparing the same and anti-microbial compositions
JPH02209876A (ja) イミダゾール誘導体
US4652564A (en) Substituted spiro pyridine derivatives as anti-allergy and antiinflammatory agents
JP5894164B2 (ja) クロメン誘導体
JPS62145049A (ja) アミノスチリル化合物及びそれを有効成分とするロイコトリエンきつ抗剤
IE860125L (en) Piperazinyl pyridines
JPH11512413A (ja) ジアリールアルケニルアミン誘導体
AU632461B2 (en) Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
US4780477A (en) Isatin compositions having anti-ulcer activities
KR940006285B1 (ko) 이환식 화합물, 이의 제조방법 및 이의 제조에 유용한 중간체
NZ235348A (en) Process for preparing substituted acetamide derivatives, and the acetamide derivatives when so prepared
US5760034A (en) Heterocyclic substituted naphthyridinones and methods and compositions employing them
JPS61249970A (ja) 新規な置換２−（ｎ−アルキニル−ｎ−フエニルアミノ）イミダゾリン誘導体
EP0309765A2 (en) 1(2H)-Phthalazinones as cytoprotective agents
JPS60174785A (ja) ピラゾロピリジン誘導体，その製法及びそれを含む医薬組成物
JPS59212469A (ja) 医薬としてのピロリン誘導体とその製法
DE3705933A1 (de) 3-n-arylamino-1-(4,5,6,7-tetrahydro-2- benzothiazolyl)-2-pyrazoline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
JPH1072439A (ja) ピリジン誘導体
JPH1059977A (ja) チエノピリジン誘導体およびそれらを含んでなる医薬

Legal Events

Date Code Title Description
RH Patent void