NO871311D0 - Zwitterioniske bicykliske forbindelser og deres salter, solvater, hydrater og estere. - Google Patents

Zwitterioniske bicykliske forbindelser og deres salter, solvater, hydrater og estere.

Info

Publication number
NO871311D0
NO871311D0 NO871311A NO871311A NO871311D0 NO 871311 D0 NO871311 D0 NO 871311D0 NO 871311 A NO871311 A NO 871311A NO 871311 A NO871311 A NO 871311A NO 871311 D0 NO871311 D0 NO 871311D0
Authority
NO
Norway
Prior art keywords
esters
switterionic
solvates
hydrates
bicyclic
Prior art date
Application number
NO871311A
Other languages
English (en)
Other versions
NO166862C (no
NO166862B (no
NO871311L (no
Inventor
David John Blythin
Ho-Jane Shue
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO871311L publication Critical patent/NO871311L/no
Publication of NO871311D0 publication Critical patent/NO871311D0/no
Publication of NO166862B publication Critical patent/NO166862B/no
Publication of NO166862C publication Critical patent/NO166862C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Outer Garments And Coats (AREA)
NO871311A 1985-07-29 1987-03-27 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,8-nafthyridinderivater og deres salter, solvater, hydrater og estere. NO166862C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/760,196 US4684727A (en) 1985-07-29 1985-07-29 Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
PCT/US1986/001518 WO1987000752A2 (en) 1985-07-29 1986-07-25 Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters

Publications (4)

Publication Number Publication Date
NO871311L NO871311L (no) 1987-03-27
NO871311D0 true NO871311D0 (no) 1987-03-27
NO166862B NO166862B (no) 1991-06-03
NO166862C NO166862C (no) 1991-09-11

Family

ID=25058394

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871311A NO166862C (no) 1985-07-29 1987-03-27 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,8-nafthyridinderivater og deres salter, solvater, hydrater og estere.

Country Status (23)

Country Link
US (4) US4684727A (no)
EP (1) EP0232328B1 (no)
JP (1) JPH0794455B2 (no)
KR (1) KR900003490B1 (no)
AT (1) ATE74756T1 (no)
AU (1) AU597587B2 (no)
CA (1) CA1263654A (no)
CZ (1) CZ413991A3 (no)
DE (1) DE3684903D1 (no)
DK (1) DK157787A (no)
FI (1) FI871345A (no)
HU (1) HU201550B (no)
IE (1) IE59298B1 (no)
IL (1) IL79556A (no)
MX (1) MX9203320A (no)
MY (1) MY101970A (no)
NO (1) NO166862C (no)
NZ (1) NZ217016A (no)
OA (1) OA08501A (no)
PH (1) PH23887A (no)
PT (1) PT83080B (no)
WO (1) WO1987000752A2 (no)
ZA (1) ZA865631B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
US5045542A (en) * 1986-10-20 1991-09-03 Schering Corporation Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
CA1309658C (en) * 1986-12-05 1992-11-03 David J. Blythin Pharmaceutical compositions for treatment of hyperproliferate skin disease
US5350755A (en) * 1986-12-05 1994-09-27 Schering Corporation Compounds and methods for treating hyperproliferative skin disease
WO1989000571A2 (en) * 1987-07-22 1989-01-26 Schering Corporation Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
US4897487A (en) * 1988-04-06 1990-01-30 Schering Corporation Process for preparing intermediates for pharmaceutically useful bicyclic compounds
US5079360A (en) * 1988-04-06 1992-01-07 Schering Corporation Processes for preparing bicyclic compounds and intermediates thereof
US5180823A (en) * 1988-04-06 1993-01-19 Schering Corporation Processes for preparing bicyclic compounds
US5341575A (en) * 1989-11-01 1994-08-30 Chisum Finis L Apparatus to gather, display, and/or print vehicle chassis measurement data for accurate repair of collision damaged vehicles
US5175151A (en) * 1990-09-07 1992-12-29 Schering Corporation Antiviral compounds and antihypertensive compounds
AU8665991A (en) * 1990-09-07 1992-03-30 Schering Corporation Antiviral compounds and antihypertensive compounds
US5760034A (en) * 1990-11-30 1998-06-02 Schering Corporation Heterocyclic substituted naphthyridinones and methods and compositions employing them
GB9026389D0 (en) * 1990-12-05 1991-01-23 Merck Sharp & Dohme Therapeutic agents
US5179093A (en) * 1991-05-10 1993-01-12 Schering Corporation Quinoline-diones
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
EP1638581A2 (en) * 2003-03-31 2006-03-29 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
WO2007092451A2 (en) 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
EP2731617A4 (en) 2011-07-12 2015-07-01 Brigham & Womens Hospital LIPID-CONTAINING PSA COMPOSITIONS, METHODS OF ISOLATION AND METHODS OF USING SAME
JP6918365B2 (ja) 2015-08-19 2021-08-11 プレジデント アンド フェローズ オブ ハーバード カレッジ 脂質化ｐｓａ組成物および方法
CA3030974A1 (en) 2016-07-15 2018-01-18 President And Fellows Of Harvard College Glycolipid compositions and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264602A (en) * 1975-08-15 1981-04-28 Sandoz, Inc. 4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
FR2469962A1 (fr) * 1979-11-21 1981-05-29 Vallourec Procede et dispositif pour la fabrication d'un tube d'acier sans soudure par laminage a chaud sur mandrin
DE3368929D1 (de) * 1982-04-26 1987-02-12 Schering Corp 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
US4452800A (en) * 1982-04-26 1984-06-05 Schering Corporation Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
US4628055A (en) * 1982-11-03 1986-12-09 Schering Corporation Method for treating allergic reactions and compositions therefore
US4551463A (en) * 1982-11-03 1985-11-05 Schering Corporation Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

Also Published As

Publication number Publication date
WO1987000752A3 (en) 1987-05-21
DK157787D0 (da) 1987-03-27
KR900003490B1 (ko) 1990-05-21
NO166862C (no) 1991-09-11
CA1263654A (en) 1989-12-05
CZ413991A3 (en) 1993-01-13
US4684727A (en) 1987-08-04
DK157787A (da) 1987-03-27
ATE74756T1 (de) 1992-05-15
AU597587B2 (en) 1990-06-07
ZA865631B (en) 1987-03-25
JPH0794455B2 (ja) 1995-10-11
EP0232328B1 (en) 1992-04-15
EP0232328A1 (en) 1987-08-19
US4902693A (en) 1990-02-20
US4782067A (en) 1988-11-01
KR870700352A (ko) 1987-12-28
DE3684903D1 (de) 1992-05-21
IE861997L (en) 1987-01-29
HU201550B (en) 1990-11-28
MX9203320A (es) 1992-07-01
NO166862B (no) 1991-06-03
PH23887A (en) 1989-12-18
IL79556A (en) 1995-05-26
NO871311L (no) 1987-03-27
FI871345A0 (fi) 1987-03-27
PT83080A (en) 1986-08-01
JPS63500453A (ja) 1988-02-18
PT83080B (pt) 1989-01-30
HUT42481A (en) 1987-07-28
WO1987000752A2 (en) 1987-02-12
FI871345A (fi) 1987-03-27
US4794116A (en) 1988-12-27
NZ217016A (en) 1989-11-28
OA08501A (en) 1988-07-29
MY101970A (en) 1992-02-29
IE59298B1 (en) 1994-02-09
AU6147986A (en) 1987-03-05

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