DK157787D0 - Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estere - Google Patents
Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estereInfo
- Publication number
- DK157787D0 DK157787D0 DK157787A DK157787A DK157787D0 DK 157787 D0 DK157787 D0 DK 157787D0 DK 157787 A DK157787 A DK 157787A DK 157787 A DK157787 A DK 157787A DK 157787 D0 DK157787 D0 DK 157787D0
- Authority
- DK
- Denmark
- Prior art keywords
- esters
- switterionic
- solvates
- hydrates
- salts
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000004677 hydrates Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 239000012453 solvate Substances 0.000 title 1
- -1 acetal ethers Chemical group 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001120 cytoprotective effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Chemical group 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 150000003568 thioethers Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Professional, Industrial, Or Sporting Protective Garments (AREA)
- Outer Garments And Coats (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/760,196 US4684727A (en) | 1985-07-29 | 1985-07-29 | Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents |
| PCT/US1986/001518 WO1987000752A2 (en) | 1985-07-29 | 1986-07-25 | Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK157787A DK157787A (da) | 1987-03-27 |
| DK157787D0 true DK157787D0 (da) | 1987-03-27 |
Family
ID=25058394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK157787A DK157787D0 (da) | 1985-07-29 | 1987-03-27 | Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estere |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US4684727A (da) |
| EP (1) | EP0232328B1 (da) |
| JP (1) | JPH0794455B2 (da) |
| KR (1) | KR900003490B1 (da) |
| AT (1) | ATE74756T1 (da) |
| AU (1) | AU597587B2 (da) |
| CA (1) | CA1263654A (da) |
| CZ (1) | CZ413991A3 (da) |
| DE (1) | DE3684903D1 (da) |
| DK (1) | DK157787D0 (da) |
| FI (1) | FI871345A0 (da) |
| HU (1) | HU201550B (da) |
| IE (1) | IE59298B1 (da) |
| IL (1) | IL79556A (da) |
| MX (1) | MX9203320A (da) |
| MY (1) | MY101970A (da) |
| NO (1) | NO166862C (da) |
| NZ (1) | NZ217016A (da) |
| OA (1) | OA08501A (da) |
| PH (1) | PH23887A (da) |
| PT (1) | PT83080B (da) |
| WO (1) | WO1987000752A2 (da) |
| ZA (1) | ZA865631B (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4684727A (en) * | 1985-07-29 | 1987-08-04 | Schering Corporation | Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents |
| US5037826A (en) * | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
| US5045542A (en) * | 1986-10-20 | 1991-09-03 | Schering Corporation | Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives |
| US5350755A (en) * | 1986-12-05 | 1994-09-27 | Schering Corporation | Compounds and methods for treating hyperproliferative skin disease |
| CA1309658C (en) * | 1986-12-05 | 1992-11-03 | David J. Blythin | Pharmaceutical compositions for treatment of hyperproliferate skin disease |
| US4897487A (en) * | 1988-04-06 | 1990-01-30 | Schering Corporation | Process for preparing intermediates for pharmaceutically useful bicyclic compounds |
| JPH07116187B2 (ja) * | 1987-07-22 | 1995-12-13 | シェリング・コーポレーション | 二環式化合物、それらを薬剤として使用すること、それらの製法、およびそれらの製造に有用な中間体 |
| US5079360A (en) * | 1988-04-06 | 1992-01-07 | Schering Corporation | Processes for preparing bicyclic compounds and intermediates thereof |
| US5180823A (en) * | 1988-04-06 | 1993-01-19 | Schering Corporation | Processes for preparing bicyclic compounds |
| US5341575A (en) * | 1989-11-01 | 1994-08-30 | Chisum Finis L | Apparatus to gather, display, and/or print vehicle chassis measurement data for accurate repair of collision damaged vehicles |
| US5412104A (en) * | 1990-09-07 | 1995-05-02 | Schering Corporation | Ester and alkoxy substituted benzopyrans |
| US5175151A (en) * | 1990-09-07 | 1992-12-29 | Schering Corporation | Antiviral compounds and antihypertensive compounds |
| US5760034A (en) * | 1990-11-30 | 1998-06-02 | Schering Corporation | Heterocyclic substituted naphthyridinones and methods and compositions employing them |
| GB9026389D0 (en) * | 1990-12-05 | 1991-01-23 | Merck Sharp & Dohme | Therapeutic agents |
| US5179093A (en) * | 1991-05-10 | 1993-01-12 | Schering Corporation | Quinoline-diones |
| JP2683783B2 (ja) * | 1992-07-10 | 1997-12-03 | 雪印乳業株式会社 | シェーグレン症候群治療剤 |
| US7083777B1 (en) * | 1999-04-02 | 2006-08-01 | The Brigham And Women's Hospital, Inc. | Immunomodulating polymers |
| SV2003000753A (es) | 2000-12-05 | 2003-06-16 | Brigham & Womens Hospital | Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico |
| WO2004089407A2 (en) * | 2003-03-31 | 2004-10-21 | The Brigham And Women's Hospital, Inc. | Zwitterionic immunomodulators for the treatment of asthma and allergy |
| US8206726B2 (en) | 2006-02-06 | 2012-06-26 | The Brigham And Women's Hospital, Inc. | Zwitterionic polysaccharides for promotion of immune system maturation and health |
| JP6273200B2 (ja) | 2011-07-12 | 2018-01-31 | ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド | 脂質含有ｐｓａ組成物、その単離の方法および使用の方法 |
| CN113637040A (zh) | 2015-08-19 | 2021-11-12 | 哈佛学院院长及董事 | 脂化psa组合物和方法 |
| EP3484441A4 (en) | 2016-07-15 | 2020-03-18 | President and Fellows of Harvard College | GLYCOLIPID COMPOSITIONS AND METHOD FOR USE |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4264602A (en) * | 1975-08-15 | 1981-04-28 | Sandoz, Inc. | 4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones |
| FR2469962A1 (fr) * | 1979-11-21 | 1981-05-29 | Vallourec | Procede et dispositif pour la fabrication d'un tube d'acier sans soudure par laminage a chaud sur mandrin |
| EP0092786B1 (en) * | 1982-04-26 | 1987-01-07 | Schering Corporation | 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives |
| US4452800A (en) * | 1982-04-26 | 1984-06-05 | Schering Corporation | Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases |
| US4628055A (en) * | 1982-11-03 | 1986-12-09 | Schering Corporation | Method for treating allergic reactions and compositions therefore |
| US4551463A (en) * | 1982-11-03 | 1985-11-05 | Schering Corporation | Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug |
| US4684727A (en) * | 1985-07-29 | 1987-08-04 | Schering Corporation | Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents |
-
1985
- 1985-07-29 US US06/760,196 patent/US4684727A/en not_active Expired - Lifetime
-
1986
- 1986-07-25 AU AU61479/86A patent/AU597587B2/en not_active Ceased
- 1986-07-25 WO PCT/US1986/001518 patent/WO1987000752A2/en not_active Ceased
- 1986-07-25 KR KR1019870700274A patent/KR900003490B1/ko not_active Expired
- 1986-07-25 HU HU862869A patent/HU201550B/hu not_active IP Right Cessation
- 1986-07-25 AT AT86904707T patent/ATE74756T1/de not_active IP Right Cessation
- 1986-07-25 PH PH34069A patent/PH23887A/en unknown
- 1986-07-25 JP JP61504059A patent/JPH0794455B2/ja not_active Expired - Lifetime
- 1986-07-25 EP EP86904707A patent/EP0232328B1/en not_active Expired - Lifetime
- 1986-07-25 DE DE8686904707T patent/DE3684903D1/de not_active Expired - Lifetime
- 1986-07-28 ZA ZA865631A patent/ZA865631B/xx unknown
- 1986-07-28 PT PT83080A patent/PT83080B/pt not_active IP Right Cessation
- 1986-07-28 IE IE199786A patent/IE59298B1/en not_active IP Right Cessation
- 1986-07-29 IL IL7955686A patent/IL79556A/en not_active IP Right Cessation
- 1986-07-29 NZ NZ217016A patent/NZ217016A/xx unknown
- 1986-07-29 CA CA000514897A patent/CA1263654A/en not_active Expired
-
1987
- 1987-03-16 OA OA59087A patent/OA08501A/xx unknown
- 1987-03-27 FI FI871345A patent/FI871345A0/fi not_active Application Discontinuation
- 1987-03-27 DK DK157787A patent/DK157787D0/da not_active IP Right Cessation
- 1987-03-27 NO NO871311A patent/NO166862C/no unknown
- 1987-07-22 US US07/076,450 patent/US4794116A/en not_active Expired - Fee Related
- 1987-07-22 US US07/076,469 patent/US4782067A/en not_active Expired - Fee Related
- 1987-08-10 MY MYPI87001247A patent/MY101970A/en unknown
-
1988
- 1988-07-22 US US07/223,458 patent/US4902693A/en not_active Expired - Fee Related
-
1991
- 1991-12-30 CZ CS914139A patent/CZ413991A3/cs unknown
-
1992
- 1992-06-25 MX MX9203320A patent/MX9203320A/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK157787A (da) | Zwitterioniske, bicykliske forbindelser og deres salte, solvater, hydrater og estere | |
| IT1205849B (it) | Derivati di indolo,procedimenti per prepararli e composizioni farmaceutiche che li contengono per il trattamento di emicrania | |
| SE8602723D0 (sv) | Thiazoles, their production and pharmaceutical compositions containing them | |
| DK249389A (da) | 2-acylamino-benzothiazol-forbindelser og deres anvendelse til fremstilling af laegemidler til behandling af tumorer | |
| ES521422A0 (es) | Procedimiento para la obtencion de derivados de carboxilamida n-glicosilados. | |
| DK0471756T3 (da) | Saccharinderivater, der er egnede som proteolytiske enzyminhibitorer, og fremstilling deraf | |
| NO891703L (no) | Farmasoeytiske sammensetninger for behandling av psoriasis. | |
| IT1216772B (it) | Derivati di indolo ,procedimento per prepararli e composizioni farmaceutiche che li contengono per il trattamento di emicrania | |
| DK23289A (da) | Disubstituerede pyridinderivater, fremgangsmaade og mellemprodukter til deres fremstilling samt deres anvendelse | |
| ES2128348T3 (es) | Obtencion de composiciones para el tratamiento de alteraciones de la proliferacion celular. | |
| IL58103A0 (en) | Sila-substituted 1,4-dihydropyridine derivatives their production and pharmaceutical compositions containing them | |
| IT1227456B (it) | Nuovi alcossi derivati di ginkgolidi, loro preparazione e composizioni terapeutiche che li contengono | |
| DK627289D0 (da) | Anvendelse af bicyclononanderivater | |
| SE8306225D0 (sv) | 2-piperazinyl-quinazoline derivatives, their production and pharmaceutical compositions containing them | |
| DK0607129T3 (da) | Methylpiperazinoazepinderivater, deres fremstilling og deres anvendelse | |
| MY103593A (en) | Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation | |
| DK478485A (da) | 4-oxo-pyrido(2,3-d)pyrimidin-derivater, deres fremstilling og anvendelse | |
| ES550285A0 (es) | Procedimiento para preparar derivados de acidos aziridin-2- carboxilicos substituidos en n | |
| SE8201308D0 (sv) | Alkylendiaminderivat och forfarande for framstellning derav | |
| SE8206217D0 (sv) | N-substituerade ergolin- och 9,10-didehydro-ergolin-8-karboxamid- och -8-aminometyl-derivat, deras framstellning och farmaceutiska kompositioner derav | |
| IT8867820A0 (it) | Procedimento di preparazione di derivati dell'1,4-benzodiazepina-4-one | |
| ES2037116T3 (es) | Procedimiento para la obtencion de bencilaminoarildihidropiridinlactonas. | |
| DK239084A (da) | 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitriler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment | ||
| PBP | Patent lapsed |