IL79308A - Isoxazole and furan derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Isoxazole and furan derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL79308A
IL79308A IL79308A IL7930886A IL79308A IL 79308 A IL79308 A IL 79308A IL 79308 A IL79308 A IL 79308A IL 7930886 A IL7930886 A IL 7930886A IL 79308 A IL79308 A IL 79308A
Authority
IL
Israel
Prior art keywords
isoxazole
preparation
pharmaceutical compositions
compositions containing
furan derivatives
Prior art date
Application number
IL79308A
Other languages
English (en)
Other versions
IL79308A0 (en
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of IL79308A0 publication Critical patent/IL79308A0/xx
Publication of IL79308A publication Critical patent/IL79308A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
IL79308A 1985-07-02 1986-07-01 Isoxazole and furan derivatives,their preparation and pharmaceutical compositions containing them IL79308A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75134885A 1985-07-02 1985-07-02

Publications (2)

Publication Number Publication Date
IL79308A0 IL79308A0 (en) 1986-10-31
IL79308A true IL79308A (en) 1991-01-31

Family

ID=25021592

Family Applications (2)

Application Number Title Priority Date Filing Date
IL79308A IL79308A (en) 1985-07-02 1986-07-01 Isoxazole and furan derivatives,their preparation and pharmaceutical compositions containing them
IL79309A IL79309A (en) 1985-07-02 1986-07-01 (heterocyclic substituted-phenoxy)alkyl-isoxazoles and-furans,their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL79309A IL79309A (en) 1985-07-02 1986-07-01 (heterocyclic substituted-phenoxy)alkyl-isoxazoles and-furans,their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
EP (2) EP0207454B1 (de)
JP (2) JPH0768242B2 (de)
KR (2) KR900001314B1 (de)
AR (4) AR241705A1 (de)
AT (2) ATE80397T1 (de)
AU (2) AU589190B2 (de)
CA (2) CA1299176C (de)
DE (3) DE3689924D1 (de)
DK (2) DK171275B1 (de)
ES (5) ES8802517A1 (de)
FI (2) FI85021C (de)
GR (2) GR861697B (de)
IE (2) IE59755B1 (de)
IL (2) IL79308A (de)
MX (4) MX2954A (de)
MY (1) MY102908A (de)
NO (2) NO164977C (de)
NZ (1) NZ216678A (de)
PH (2) PH22321A (de)
PT (2) PT82892B (de)
ZA (2) ZA864872B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
US5051437A (en) * 1986-06-24 1991-09-24 Sterling Drug Inc. Thiazolylphenoxyalkylisoxazoles, related compounds, and their use as antiviral agents
GB8807275D0 (en) * 1988-03-26 1988-04-27 Synphar Lab Inc Chemical compounds
ATE186552T1 (de) 1988-09-01 1999-11-15 Bayer Ag Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
US5070090A (en) * 1989-05-15 1991-12-03 Janssen Pharmaceutica N.V. Antipicorpaviral herterocyclic-substituted morpholinyl alkylphenol ethers
GB8911158D0 (en) * 1989-05-16 1989-07-05 Janssen Pharmaceutica Nv Antiviral pyridazinamines
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US5110821A (en) * 1989-08-18 1992-05-05 Sterling Drug Inc. 1,3,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
DK0468257T3 (da) * 1990-07-20 2000-03-27 Bayer Ag Multimer form af human rhinovirusreceptorprotein
US5674982A (en) * 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
IT1247509B (it) * 1991-04-19 1994-12-17 Univ Cagliari Composti di sintesi atti all'impiego nella terapia delle infezioni da rhinovirus
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5514781A (en) * 1994-04-11 1996-05-07 Bayer Corporation Use of azoles as virucidal agents in solutions of biologically active proteins
US5453433A (en) * 1994-05-13 1995-09-26 Sterling Winthrop Inc. Thiadiazoles and antipicornaviral compositions
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
EP1644368B1 (de) 2003-07-02 2008-08-27 F. Hoffmann-La Roche Ag Indol-derivate, die durch einen thiazol ring substituiert sind und deren verwendung als ppar modulatoren
EP1866293A1 (de) 2005-03-31 2007-12-19 UCB Pharma, S.A. Eine oxazol- oder thiazolgruppe enthaltende verbindungen, verfahren zu deren herstellung und ihre anwendungen
JP2012532102A (ja) * 2009-06-30 2012-12-13 シガ・テクノロジーズ・インコーポレーテッド デングウイルス感染の治療法および予防法
US8993604B2 (en) 2009-06-30 2015-03-31 Siga Technologies, Inc. Treatment and prevention of dengue virus infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451476A (en) * 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
CA1280753C (en) 1991-02-26
JPH0819128B2 (ja) 1996-02-28
MX2954A (es) 1993-11-01
ES8802517A1 (es) 1988-07-01
EP0207454A3 (en) 1988-08-10
KR900001314B1 (ko) 1990-03-08
ES557778A0 (es) 1988-04-01
EP0207453A3 (en) 1988-11-23
EP0207453B1 (de) 1994-06-22
DE3686677D1 (de) 1992-10-15
DK173467B1 (da) 2000-12-04
IE59755B1 (en) 1994-03-23
NO164977C (no) 1990-12-05
DK171275B1 (da) 1996-08-19
FI85021C (fi) 1992-02-25
DE3686677T2 (de) 1993-03-11
IE861724L (en) 1987-01-02
ES8801649A1 (es) 1988-02-16
PH22321A (en) 1988-07-29
NZ216678A (en) 1989-10-27
PT82891B (pt) 1988-05-27
NO862651L (no) 1987-01-05
ES8802518A1 (es) 1988-07-01
NO862650D0 (no) 1986-07-01
FI862795A (fi) 1987-01-03
ATE107645T1 (de) 1994-07-15
IE66234B1 (en) 1995-12-13
AR242572A1 (es) 1993-04-30
DK312986D0 (da) 1986-07-01
ZA864872B (en) 1987-02-25
AR241705A1 (es) 1992-11-30
FI85021B (fi) 1991-11-15
ES8801651A1 (es) 1988-02-16
AR244686A1 (es) 1993-11-30
PT82891A (en) 1986-08-01
DE3689924D1 (de) 1994-07-28
ES557779A0 (es) 1988-02-16
AU587622B2 (en) 1989-08-24
MY102908A (en) 1993-03-31
NO862650L (no) 1987-01-05
FI862794A (fi) 1987-01-03
IL79309A0 (en) 1986-10-31
AU589190B2 (en) 1989-10-05
AR242573A1 (es) 1993-04-30
PH23197A (en) 1989-05-29
KR870001202A (ko) 1987-03-12
JPS6216479A (ja) 1987-01-24
JPH0768242B2 (ja) 1995-07-26
IL79308A0 (en) 1986-10-31
EP0207453A2 (de) 1987-01-07
ES556811A0 (es) 1988-07-01
MX9100032A (es) 1993-01-01
JPS6216480A (ja) 1987-01-24
MX9100029A (es) 1993-01-01
ES556812A0 (es) 1988-07-01
DK312986A (da) 1987-01-03
NO164977B (no) 1990-08-27
AU5945686A (en) 1987-01-08
KR870001205A (ko) 1987-03-12
DE3689924T2 (de) 1995-01-19
IE861723L (en) 1987-01-02
DK313086A (da) 1987-01-03
KR900001315B1 (ko) 1990-03-08
IL79309A (en) 1990-11-29
PT82892B (pt) 1994-09-30
ES8802153A1 (es) 1988-04-01
AU5945786A (en) 1987-01-08
GR861695B (en) 1986-11-04
MX9100033A (es) 1993-01-01
DK313086D0 (da) 1986-07-01
ZA864873B (en) 1987-02-25
CA1299176C (en) 1992-04-21
NO862651D0 (no) 1986-07-01
DE3689924T4 (de) 1995-05-11
GR861697B (en) 1986-11-04
NO165023C (no) 1990-12-12
FI862795A0 (fi) 1986-07-01
EP0207454A2 (de) 1987-01-07
FI862794A0 (fi) 1986-07-01
PT82892A (pt) 1987-01-26
ES557780A0 (es) 1988-02-16
ATE80397T1 (de) 1992-09-15
EP0207454B1 (de) 1992-09-09
NO165023B (no) 1990-09-03

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Legal Events

Date Code Title Description
KB Patent renewed
HP Change in proprietorship
HP Change in proprietorship
MM9K Patent not in force due to non-payment of renewal fees