NO862650D0 - Fremgangsmaate for fremstilling av heterocykliske substituert-fenoksyalkyl isoksazoler og -furaner. - Google Patents

Fremgangsmaate for fremstilling av heterocykliske substituert-fenoksyalkyl isoksazoler og -furaner.

Info

Publication number
NO862650D0
NO862650D0 NO862650A NO862650A NO862650D0 NO 862650 D0 NO862650 D0 NO 862650D0 NO 862650 A NO862650 A NO 862650A NO 862650 A NO862650 A NO 862650A NO 862650 D0 NO862650 D0 NO 862650D0
Authority
NO
Norway
Prior art keywords
phenoxylycyl
isoxsazols
furanes
procedure
preparation
Prior art date
Application number
NO862650A
Other languages
English (en)
Other versions
NO862650L (no
NO165023B (no
NO165023C (no
Inventor
Guy Dominic Diana
Philip Michael Carabateas
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of NO862650D0 publication Critical patent/NO862650D0/no
Publication of NO862650L publication Critical patent/NO862650L/no
Publication of NO165023B publication Critical patent/NO165023B/no
Publication of NO165023C publication Critical patent/NO165023C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
NO862650A 1985-07-02 1986-07-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive isoksazol- og furan derivater. NO165023C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75134885A 1985-07-02 1985-07-02

Publications (4)

Publication Number Publication Date
NO862650D0 true NO862650D0 (no) 1986-07-01
NO862650L NO862650L (no) 1987-01-05
NO165023B NO165023B (no) 1990-09-03
NO165023C NO165023C (no) 1990-12-12

Family

ID=25021592

Family Applications (2)

Application Number Title Priority Date Filing Date
NO862650A NO165023C (no) 1985-07-02 1986-07-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive isoksazol- og furan derivater.
NO862651A NO164977C (no) 1985-07-02 1986-07-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske substituert-fenoksyalkylisoksazoler og -furaner.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO862651A NO164977C (no) 1985-07-02 1986-07-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske substituert-fenoksyalkylisoksazoler og -furaner.

Country Status (21)

Country Link
EP (2) EP0207454B1 (no)
JP (2) JPH0819128B2 (no)
KR (2) KR900001314B1 (no)
AR (4) AR241705A1 (no)
AT (2) ATE80397T1 (no)
AU (2) AU589190B2 (no)
CA (2) CA1280753C (no)
DE (3) DE3686677T2 (no)
DK (2) DK173467B1 (no)
ES (5) ES8802517A1 (no)
FI (2) FI862795A (no)
GR (2) GR861695B (no)
IE (2) IE59755B1 (no)
IL (2) IL79309A (no)
MX (4) MX2954A (no)
MY (1) MY102908A (no)
NO (2) NO165023C (no)
NZ (1) NZ216678A (no)
PH (2) PH23197A (no)
PT (2) PT82891B (no)
ZA (2) ZA864873B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1280753C (en) * 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
US5051437A (en) * 1986-06-24 1991-09-24 Sterling Drug Inc. Thiazolylphenoxyalkylisoxazoles, related compounds, and their use as antiviral agents
GB8807275D0 (en) * 1988-03-26 1988-04-27 Synphar Lab Inc Chemical compounds
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
EP0362531B1 (en) 1988-09-01 1999-11-10 Bayer Corporation A human rhinovirus receptor protein that inhibits virus infectivity
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US5070090A (en) * 1989-05-15 1991-12-03 Janssen Pharmaceutica N.V. Antipicorpaviral herterocyclic-substituted morpholinyl alkylphenol ethers
GB8911158D0 (en) * 1989-05-16 1989-07-05 Janssen Pharmaceutica Nv Antiviral pyridazinamines
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5110821A (en) * 1989-08-18 1992-05-05 Sterling Drug Inc. 1,3,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US5871733A (en) * 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
ES2134762T3 (es) * 1990-07-20 1999-10-16 Bayer Ag Formas multimericas de proteinas receptoras de rinovirus humanos.
IT1247509B (it) * 1991-04-19 1994-12-17 Univ Cagliari Composti di sintesi atti all'impiego nella terapia delle infezioni da rhinovirus
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5514781A (en) * 1994-04-11 1996-05-07 Bayer Corporation Use of azoles as virucidal agents in solutions of biologically active proteins
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
US5453433A (en) * 1994-05-13 1995-09-26 Sterling Winthrop Inc. Thiadiazoles and antipicornaviral compositions
KR100796093B1 (ko) 2003-07-02 2008-01-21 에프. 호프만-라 로슈 아게 티아졸 고리로 치환된 인돌릴 유도체 및 ppar조절제로서 그의 용도
EP1866293A1 (en) 2005-03-31 2007-12-19 UCB Pharma, S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
US8993604B2 (en) 2009-06-30 2015-03-31 Siga Technologies, Inc. Treatment and prevention of dengue virus infections
EP2448410A4 (en) * 2009-06-30 2013-12-18 Siga Technologies Inc TREATMENT AND PREVENTION OF INFECTIONS WITH THE DENGUE VIRUS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451476A (en) * 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions
CA1280753C (en) * 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans

Also Published As

Publication number Publication date
DE3689924T2 (de) 1995-01-19
JPH0768242B2 (ja) 1995-07-26
IL79308A0 (en) 1986-10-31
EP0207453A3 (en) 1988-11-23
EP0207453B1 (en) 1994-06-22
DE3689924T4 (de) 1995-05-11
NO164977B (no) 1990-08-27
IE59755B1 (en) 1994-03-23
IL79308A (en) 1991-01-31
ATE80397T1 (de) 1992-09-15
DK313086A (da) 1987-01-03
DK312986A (da) 1987-01-03
EP0207453A2 (en) 1987-01-07
ES8801651A1 (es) 1988-02-16
DK313086D0 (da) 1986-07-01
KR870001202A (ko) 1987-03-12
IE66234B1 (en) 1995-12-13
KR900001315B1 (ko) 1990-03-08
IE861723L (en) 1987-01-02
KR870001205A (ko) 1987-03-12
EP0207454B1 (en) 1992-09-09
MX9100033A (es) 1993-01-01
JPH0819128B2 (ja) 1996-02-28
ES8802518A1 (es) 1988-07-01
DE3686677D1 (de) 1992-10-15
FI85021C (fi) 1992-02-25
IL79309A0 (en) 1986-10-31
PT82892B (pt) 1994-09-30
CA1299176C (en) 1992-04-21
IE861724L (en) 1987-01-02
ES557780A0 (es) 1988-02-16
ES556811A0 (es) 1988-07-01
IL79309A (en) 1990-11-29
EP0207454A3 (en) 1988-08-10
AU589190B2 (en) 1989-10-05
ATE107645T1 (de) 1994-07-15
FI862794A (fi) 1987-01-03
AR241705A1 (es) 1992-11-30
AU587622B2 (en) 1989-08-24
ZA864873B (en) 1987-02-25
DK171275B1 (da) 1996-08-19
ES556812A0 (es) 1988-07-01
FI862795A (fi) 1987-01-03
MY102908A (en) 1993-03-31
ES557778A0 (es) 1988-04-01
DE3689924D1 (de) 1994-07-28
MX9100029A (es) 1993-01-01
JPS6216480A (ja) 1987-01-24
GR861695B (en) 1986-11-04
MX9100032A (es) 1993-01-01
AU5945786A (en) 1987-01-08
FI85021B (fi) 1991-11-15
GR861697B (en) 1986-11-04
PH23197A (en) 1989-05-29
PT82891B (pt) 1988-05-27
AR244686A1 (es) 1993-11-30
NO862650L (no) 1987-01-05
PT82891A (en) 1986-08-01
ES8802517A1 (es) 1988-07-01
NO862651D0 (no) 1986-07-01
PT82892A (pt) 1987-01-26
AU5945686A (en) 1987-01-08
NO165023B (no) 1990-09-03
DE3686677T2 (de) 1993-03-11
KR900001314B1 (ko) 1990-03-08
PH22321A (en) 1988-07-29
EP0207454A2 (en) 1987-01-07
NZ216678A (en) 1989-10-27
MX2954A (es) 1993-11-01
NO165023C (no) 1990-12-12
AR242573A1 (es) 1993-04-30
ES8801649A1 (es) 1988-02-16
ZA864872B (en) 1987-02-25
CA1280753C (en) 1991-02-26
NO164977C (no) 1990-12-05
AR242572A1 (es) 1993-04-30
DK312986D0 (da) 1986-07-01
FI862795A0 (fi) 1986-07-01
JPS6216479A (ja) 1987-01-24
ES8802153A1 (es) 1988-04-01
FI862794A0 (fi) 1986-07-01
DK173467B1 (da) 2000-12-04
NO862651L (no) 1987-01-05
ES557779A0 (es) 1988-02-16

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Legal Events

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