IL78301A - 7-beta-(2-(2-amino-4-thiazolyl)-2-alkenoylamino)-3-cephem-4-carboxylic acid esters,processes for the preparation thereof and anti-bacterial compositions containing the same - Google Patents

7-beta-(2-(2-amino-4-thiazolyl)-2-alkenoylamino)-3-cephem-4-carboxylic acid esters,processes for the preparation thereof and anti-bacterial compositions containing the same

Info

Publication number
IL78301A
IL78301A IL78301A IL7830186A IL78301A IL 78301 A IL78301 A IL 78301A IL 78301 A IL78301 A IL 78301A IL 7830186 A IL7830186 A IL 7830186A IL 78301 A IL78301 A IL 78301A
Authority
IL
Israel
Prior art keywords
alkenoylamino
cephem
thiazolyl
beta
amino
Prior art date
Application number
IL78301A
Other languages
English (en)
Other versions
IL78301A0 (en
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of IL78301A0 publication Critical patent/IL78301A0/xx
Publication of IL78301A publication Critical patent/IL78301A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL78301A 1985-03-29 1986-03-28 7-beta-(2-(2-amino-4-thiazolyl)-2-alkenoylamino)-3-cephem-4-carboxylic acid esters,processes for the preparation thereof and anti-bacterial compositions containing the same IL78301A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6728085 1985-03-29

Publications (2)

Publication Number Publication Date
IL78301A0 IL78301A0 (en) 1986-07-31
IL78301A true IL78301A (en) 1991-07-18

Family

ID=13340398

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78301A IL78301A (en) 1985-03-29 1986-03-28 7-beta-(2-(2-amino-4-thiazolyl)-2-alkenoylamino)-3-cephem-4-carboxylic acid esters,processes for the preparation thereof and anti-bacterial compositions containing the same

Country Status (19)

Country Link
US (1) US4731361A (es)
JP (1) JPS6289A (es)
KR (1) KR870001983B1 (es)
AT (1) AT392471B (es)
AU (1) AU580855B2 (es)
BE (1) BE904517A (es)
BR (1) BR1100475A (es)
CA (1) CA1269655A (es)
CH (1) CH669600A5 (es)
DE (1) DE3610581A1 (es)
ES (2) ES8800237A1 (es)
FR (1) FR2579597B1 (es)
GB (1) GB2173194B (es)
GR (1) GR860838B (es)
HK (1) HK47993A (es)
IL (1) IL78301A (es)
IT (1) IT1191997B (es)
NL (1) NL192926C (es)
SU (3) SU1581223A3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
US5017380A (en) * 1986-07-02 1991-05-21 Shionogi & Co., Ltd. Gelatin hard capsule containing crystalline hydrate of oral cephalosporin
US5242913A (en) * 1987-03-11 1993-09-07 Pfizer Inc. Substituted 3-cephem compounds as antibacterial agents
MA21530A1 (fr) * 1988-04-06 1989-12-31 Beecham Group Plc Nouveaux composes contenant le cycle betalactame, et leur procede de preparation .
US5245027A (en) * 1989-11-21 1993-09-14 Bristol-Myers Squibb Company 3-fluorosulfonyloxyceph-3-em compounds
TW203552B (en) * 1992-02-18 1993-04-11 J Baroody Lloyd Compositions of clindamycin and benzoyl peroxide for acne treatment
JP2002356427A (ja) * 2001-05-30 2002-12-13 Shionogi & Co Ltd β−ラクタマーゼ阻害剤
TWI364282B (en) * 2005-01-31 2012-05-21 Shionogi & Co Cefcapene pivoxil methanesulfonic acid salt
WO2008155615A2 (en) * 2007-06-18 2008-12-24 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of cephalosporin antibiotic
CN101747344B (zh) * 2009-12-22 2012-07-04 山东润泽制药有限公司 盐酸头孢卡品酯的合成方法
CN103087080B (zh) * 2011-11-03 2016-08-31 石药集团中奇制药技术（石家庄）有限公司 一种盐酸头孢卡品酯的制备方法及其合成中间体

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575803A (en) * 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
DE2760484C2 (es) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
GB2076801A (en) * 1980-04-14 1981-12-09 Erba Farmitalia alpha , beta -Disubstituted Acrylamido Cephalosporins
DE3037997A1 (de) * 1980-10-08 1982-05-13 Bayer Ag (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
DE3145727A1 (de) * 1981-11-19 1983-05-26 Bayer Ag, 5090 Leverkusen Zwischenprodukte, verfahren zu deren herstellung und verfahren zur herstellung von cephalosporinen
CA1201431A (en) * 1981-12-17 1986-03-04 Daiei Tunemoto .beta.-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF
DE3239365A1 (de) * 1982-10-23 1984-04-26 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
JPS5984890A (ja) * 1982-11-05 1984-05-16 Hisayasu Ishimaru 経口用セフアロスポリン化合物
DE3300593A1 (de) * 1983-01-11 1984-07-12 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
JPS6051193A (ja) * 1983-08-31 1985-03-22 Kyoto Yakuhin Kogyo Kk セフェム系化合物
AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
DE3343208A1 (de) * 1983-11-30 1985-06-05 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
EP0187456A1 (en) * 1984-11-29 1986-07-16 Ici Pharma Cephalosporin derivatives

Also Published As

Publication number Publication date
GB8607855D0 (en) 1986-04-30
GR860838B (en) 1986-07-29
US4731361A (en) 1988-03-15
GB2173194A (en) 1986-10-08
ES8800237A1 (es) 1987-11-01
IL78301A0 (en) 1986-07-31
IT1191997B (it) 1988-03-31
CH669600A5 (es) 1989-03-31
AU5520486A (en) 1986-10-02
ATA82386A (de) 1990-09-15
AT392471B (de) 1991-04-10
GB2173194B (en) 1989-06-28
IT8667257A0 (it) 1986-03-28
DE3610581C2 (es) 1993-04-01
BR1100475A (pt) 1999-10-05
FR2579597A1 (fr) 1986-10-03
SU1575941A3 (ru) 1990-06-30
SU1581223A3 (ru) 1990-07-23
KR860007266A (ko) 1986-10-10
ES553426A0 (es) 1987-11-01
BE904517A (fr) 1986-07-16
NL8600804A (nl) 1986-10-16
AU580855B2 (en) 1989-02-02
ES8801922A1 (es) 1988-03-16
CA1269655A (en) 1990-05-29
JPS6289A (ja) 1987-01-06
KR870001983B1 (ko) 1987-10-24
SU1556541A3 (ru) 1990-04-07
FR2579597B1 (fr) 1991-04-12
NL192926C (nl) 1998-05-07
HK47993A (en) 1993-05-27
NL192926B (nl) 1998-01-05
DE3610581A1 (de) 1986-10-02
JPH0588715B2 (es) 1993-12-24
ES557640A0 (es) 1988-03-16

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Legal Events

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