IL75277A - Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gramnegative bacteria,pharmaceutical formulations composing them and lyphocyte cell lines secreting them - Google Patents
Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gramnegative bacteria,pharmaceutical formulations composing them and lyphocyte cell lines secreting themInfo
- Publication number
- IL75277A IL75277A IL75277A IL7527785A IL75277A IL 75277 A IL75277 A IL 75277A IL 75277 A IL75277 A IL 75277A IL 7527785 A IL7527785 A IL 7527785A IL 75277 A IL75277 A IL 75277A
- Authority
- IL
- Israel
- Prior art keywords
- crl
- cell lines
- monoclonal antibodies
- human monoclonal
- serotypic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/803—Antibody or antigen-binding fragment thereof that binds gram-negative bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/806—Drug, bio-affecting and body treating compositions involving IgM
- Y10S424/807—Monoclonal
- Y10S424/808—Human
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/948—Microorganisms using viruses or cell lines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
- Y10S530/864—Monoclonal
- Y10S530/865—Human
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61418484A | 1984-05-25 | 1984-05-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL75277A0 IL75277A0 (en) | 1985-09-29 |
IL75277A true IL75277A (en) | 1990-02-09 |
Family
ID=24460190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL75277A IL75277A (en) | 1984-05-25 | 1985-05-22 | Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gramnegative bacteria,pharmaceutical formulations composing them and lyphocyte cell lines secreting them |
Country Status (16)
Country | Link |
---|---|
US (1) | US4834975A (el) |
EP (1) | EP0163493B1 (el) |
JP (1) | JPS6169796A (el) |
KR (1) | KR850008282A (el) |
AT (1) | ATE62021T1 (el) |
AU (1) | AU600222B2 (el) |
DE (1) | DE3582274D1 (el) |
DK (1) | DK233385A (el) |
ES (1) | ES8702792A1 (el) |
FI (1) | FI89278C (el) |
GR (1) | GR851234B (el) |
HU (1) | HU202927B (el) |
IE (1) | IE58411B1 (el) |
IL (1) | IL75277A (el) |
NO (1) | NO167758C (el) |
ZA (1) | ZA853888B (el) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
JPS61152280A (ja) * | 1984-12-26 | 1986-07-10 | Teijin Ltd | 抗緑膿菌ヒト抗体を産生する形質転換細胞及びその製造法並びにその使用方法 |
WO1986003754A1 (en) * | 1984-12-26 | 1986-07-03 | Teijin Limited | Anti-pseudomonas aeruginosa human monoclonal antibody |
JPS61155398A (ja) * | 1984-12-28 | 1986-07-15 | Teijin Ltd | 抗緑膿菌ヒトモノクロ−ナル抗体及びその製造法並びにそれを有効成分とする治療剤 |
EP0215131B1 (en) * | 1985-03-11 | 1992-06-17 | Teijin Limited | E87ag antigen of pseudomonas aeruginosa, monoclonal antibody against it, and hybridoma |
US4918163A (en) * | 1985-09-27 | 1990-04-17 | Pfizer Inc. | Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria |
US4777136A (en) * | 1985-09-27 | 1988-10-11 | The Regents Of The University Of California | Monoclonal antibody reactive with Pseudomonas Aeruginosa |
US5179001A (en) * | 1985-09-27 | 1993-01-12 | The Regents Of The University Of California | Detection and monitoring of chronic and gram-negative infection |
EP0494085A1 (en) | 1985-09-27 | 1992-07-08 | The Regents Of The University Of California | Monoclonal antibodies binding determinants of gram negative bacteria |
NZ218499A (en) * | 1985-12-10 | 1990-04-26 | Genetic Systems Corp | Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods |
ZA87863B (en) * | 1986-02-07 | 1987-09-30 | Genetic Systems Corp | Cross-protective human monoclonal antibody compositions |
IL81370A (en) * | 1986-02-07 | 1991-06-30 | Genetic Systems Corp | Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions |
US4970070A (en) * | 1986-02-07 | 1990-11-13 | Genetic Systems Corporation | Protective monoclonal antibody compositions for infections due to group B streptococcus |
ES2009366A6 (es) * | 1986-04-24 | 1989-09-16 | Univ California | Procedimiento de obtencion de anticuerpos monoclonales para bacterias gram-negativas. |
GB8610202D0 (en) * | 1986-04-25 | 1986-05-29 | Technology Licence Co Ltd | Monoclonal antibodies |
EP0256713A3 (en) * | 1986-08-06 | 1989-02-15 | Merck & Co. Inc. | Therapeutic human antipseudomonas aeruginosa antibodies |
ZA878610B (en) * | 1986-11-20 | 1989-06-28 | Minnesota Mining & Mfg | Method for the evaluation of oral microbes |
US5521085A (en) * | 1986-12-15 | 1996-05-28 | Mitsui Toatsu Chemicals, Inc. | Transformed cell lines producing human monoclonal antibodies specific for Pseudomonas aeruginosa serotypes |
WO1988008135A1 (en) * | 1987-04-10 | 1988-10-20 | Xoma Corporation | Human monoclonal antibodies binding determinants of gram negative bacteria |
DE3875852T2 (de) * | 1987-08-10 | 1993-03-18 | Miles Inc | Gereinigtes igm. |
JPH01197500A (ja) * | 1988-01-29 | 1989-08-09 | Sumitomo Chem Co Ltd | ヒトモノクローナル抗体 |
GB2218703B (en) * | 1988-05-10 | 1992-10-28 | Sumitomo Chemical Co | Human monoclonal antibody to p.aeruginosa: its production and use |
US5439665A (en) * | 1988-07-29 | 1995-08-08 | Immunomedics | Detection and treatment of infectious and inflammatory lesions |
CA1341375C (en) * | 1988-10-12 | 2002-07-09 | Baxter International Inc. | Compositions and methods for the treatment and prevention of gram-negative bacterial infections |
US4939176A (en) * | 1988-12-20 | 1990-07-03 | Miles Inc. | Viral inactivation process |
JPH02283294A (ja) * | 1989-04-24 | 1990-11-20 | Sumitomo Chem Co Ltd | ヒトモノクローナル抗体 |
US5233024A (en) * | 1991-04-09 | 1993-08-03 | The Brigham & Women's Hospital | Anti-idiotypic monoclonal antibodies for mucoid pseudomonas aeruginosa, their preparation and use |
US5824310A (en) * | 1991-10-22 | 1998-10-20 | The United States Of America As Represented By The Department Of Health And Human Services | Lipopplysaccharide conjugate vaccines |
CA2085448C (en) * | 1991-12-24 | 2003-11-18 | Masakazu Tsuchiya | Process for extracting endotoxin |
US5610031A (en) * | 1993-10-27 | 1997-03-11 | The General Hospital Corporation | B1k chain of laminin and methods of use |
US5562902A (en) * | 1994-03-14 | 1996-10-08 | Arp Biomed, Inc. | Immunotherapeutic method of treating cancerous diseases by administration of intravenous immunoglobulin |
US5807694A (en) * | 1995-09-07 | 1998-09-15 | Economic Innovation And Technology Council, University Of Manitoba | Detection of salmonella enteritidis and other pathogenic microorganisms and monoclonal antibody useful therefor |
US6818222B1 (en) * | 1997-03-21 | 2004-11-16 | Chiron Corporation | Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants |
JP4499839B2 (ja) * | 1997-05-15 | 2010-07-07 | ベリタス・セラピューティクス・インコーポレイテッド | 免疫性凝固を調節する方法 |
US6790661B1 (en) | 1999-07-16 | 2004-09-14 | Verax Biomedical, Inc. | System for detecting bacteria in blood, blood products, and fluids of tissues |
AU2001237471A1 (en) * | 2000-02-15 | 2001-08-27 | Finnish Immunotechnology Ltd | Immunochemical methods |
DE60331292D1 (de) * | 2003-05-14 | 2010-04-01 | Kenta Biotech Ag | Humaner monoklonaler Antikörper spezifisch für Lipopolysacchariden (LPS) des Serotyps IATS O6 von Pseudomonas aeruginosa |
JP2012523221A (ja) | 2009-04-09 | 2012-10-04 | ケンタ バイオテク アーゲー | 緑膿菌(Pseudomonasaeruginosa)のIATSO1血清型のリポ多糖類(LPS)に対して特異的なヒトモノクローナル抗体 |
CN102858799A (zh) * | 2010-02-18 | 2013-01-02 | 明治制果药业株式会社 | 抗铜绿假单胞菌的i血清型脂多糖的抗体 |
EP2361989A1 (en) * | 2010-02-26 | 2011-08-31 | Kenta Biotech AG | Assays and kits for serotyping Pseudomonas aeruginosa and oligonucleotide sequences useful in such methods and kits |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE57107T1 (de) * | 1981-01-28 | 1983-04-14 | Coats Patons Plc, Glasgow, Scotland | Verfahren zur herstellung von monoklonalen antikoerpern und zellen, faehig diese antikoerper herzustellen. |
US4464465A (en) * | 1982-04-05 | 1984-08-07 | Genetic Systems Corporation | Cell-driven viral transfer in eukaryotes |
JPS5929622A (ja) * | 1982-08-10 | 1984-02-16 | Meiji Seika Kaisha Ltd | モノクロ−ナル抗体、その製造法およびその用途 |
AU567693B2 (en) * | 1982-09-30 | 1987-12-03 | University Of Rochester | Human monoclonal antibodies against bacterial toxins |
JPH0776240B2 (ja) * | 1983-05-06 | 1995-08-16 | ベロス グル−プ | エンドトキシンコア−と反応性のモノクロ−ナル抗体 |
US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
-
1985
- 1985-05-15 US US06/734,624 patent/US4834975A/en not_active Expired - Fee Related
- 1985-05-21 FI FI852029A patent/FI89278C/fi not_active IP Right Cessation
- 1985-05-21 GR GR851234A patent/GR851234B/el unknown
- 1985-05-22 ZA ZA853888A patent/ZA853888B/xx unknown
- 1985-05-22 IL IL75277A patent/IL75277A/xx unknown
- 1985-05-23 DE DE8585303642T patent/DE3582274D1/de not_active Revoked
- 1985-05-23 EP EP85303642A patent/EP0163493B1/en not_active Expired - Lifetime
- 1985-05-23 AT AT85303642T patent/ATE62021T1/de not_active IP Right Cessation
- 1985-05-24 DK DK233385A patent/DK233385A/da not_active Application Discontinuation
- 1985-05-24 AU AU42858/85A patent/AU600222B2/en not_active Ceased
- 1985-05-24 HU HU851986A patent/HU202927B/hu not_active IP Right Cessation
- 1985-05-24 JP JP60110583A patent/JPS6169796A/ja active Pending
- 1985-05-24 IE IE130285A patent/IE58411B1/en not_active IP Right Cessation
- 1985-05-24 NO NO85852093A patent/NO167758C/no unknown
- 1985-05-24 ES ES543474A patent/ES8702792A1/es not_active Expired
- 1985-05-25 KR KR1019850003622A patent/KR850008282A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HU202927B (en) | 1991-04-29 |
NO852093L (no) | 1985-11-26 |
NO167758B (no) | 1991-08-26 |
IE851302L (en) | 1985-11-25 |
DK233385D0 (da) | 1985-05-24 |
EP0163493B1 (en) | 1991-03-27 |
FI89278C (fi) | 1993-09-10 |
EP0163493A2 (en) | 1985-12-04 |
FI852029L (fi) | 1985-11-26 |
FI852029A0 (fi) | 1985-05-21 |
KR850008282A (ko) | 1985-12-16 |
US4834975A (en) | 1989-05-30 |
DE3582274D1 (de) | 1991-05-02 |
GR851234B (el) | 1985-07-01 |
IE58411B1 (en) | 1993-09-22 |
ZA853888B (en) | 1986-01-29 |
ATE62021T1 (de) | 1991-04-15 |
HUT38123A (en) | 1986-04-28 |
FI89278B (fi) | 1993-05-31 |
EP0163493A3 (en) | 1986-07-02 |
ES543474A0 (es) | 1987-01-16 |
ES8702792A1 (es) | 1987-01-16 |
AU4285885A (en) | 1985-11-28 |
JPS6169796A (ja) | 1986-04-10 |
NO167758C (no) | 1991-12-04 |
AU600222B2 (en) | 1990-08-09 |
DK233385A (da) | 1985-11-26 |
IL75277A0 (en) | 1985-09-29 |
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