ATE62021T1 - Menschliche monoklonale antikoerper gegen serotypische lipopolysaccharidische determinanten von gram-negativen bakterien und ihre produktion. - Google Patents

Menschliche monoklonale antikoerper gegen serotypische lipopolysaccharidische determinanten von gram-negativen bakterien und ihre produktion.

Info

Publication number
ATE62021T1
ATE62021T1 AT85303642T AT85303642T ATE62021T1 AT E62021 T1 ATE62021 T1 AT E62021T1 AT 85303642 T AT85303642 T AT 85303642T AT 85303642 T AT85303642 T AT 85303642T AT E62021 T1 ATE62021 T1 AT E62021T1
Authority
AT
Austria
Prior art keywords
crl
gram
monoclonal antibodies
human monoclonal
serotypic
Prior art date
Application number
AT85303642T
Other languages
English (en)
Inventor
Anthony W Siadak
Mark E Lostrom
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24460190&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE62021(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Application granted granted Critical
Publication of ATE62021T1 publication Critical patent/ATE62021T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/803—Antibody or antigen-binding fragment thereof that binds gram-negative bacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/806—Drug, bio-affecting and body treating compositions involving IgM
    • Y10S424/807—Monoclonal
    • Y10S424/808—Human
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
    • Y10S530/864—Monoclonal
    • Y10S530/865—Human

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT85303642T 1984-05-25 1985-05-23 Menschliche monoklonale antikoerper gegen serotypische lipopolysaccharidische determinanten von gram-negativen bakterien und ihre produktion. ATE62021T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61418484A 1984-05-25 1984-05-25
EP85303642A EP0163493B1 (de) 1984-05-25 1985-05-23 Menschliche monoklonale Antikörper gegen serotypische lipopolysaccharidische Determinanten von gram-negativen Bakterien und ihre Produktion

Publications (1)

Publication Number Publication Date
ATE62021T1 true ATE62021T1 (de) 1991-04-15

Family

ID=24460190

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85303642T ATE62021T1 (de) 1984-05-25 1985-05-23 Menschliche monoklonale antikoerper gegen serotypische lipopolysaccharidische determinanten von gram-negativen bakterien und ihre produktion.

Country Status (16)

Country Link
US (1) US4834975A (de)
EP (1) EP0163493B1 (de)
JP (1) JPS6169796A (de)
KR (1) KR850008282A (de)
AT (1) ATE62021T1 (de)
AU (1) AU600222B2 (de)
DE (1) DE3582274D1 (de)
DK (1) DK233385A (de)
ES (1) ES8702792A1 (de)
FI (1) FI89278C (de)
GR (1) GR851234B (de)
HU (1) HU202927B (de)
IE (1) IE58411B1 (de)
IL (1) IL75277A (de)
NO (1) NO167758C (de)
ZA (1) ZA853888B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
AU597877B2 (en) * 1984-12-26 1990-06-14 Teijin Limited Anti-pseudomonas aeruginosa human monoclonal antibody
JPS61155398A (ja) * 1984-12-28 1986-07-15 Teijin Ltd 抗緑膿菌ヒトモノクロ−ナル抗体及びその製造法並びにそれを有効成分とする治療剤
JPS61152280A (ja) * 1984-12-26 1986-07-10 Teijin Ltd 抗緑膿菌ヒト抗体を産生する形質転換細胞及びその製造法並びにその使用方法
EP0215131B1 (de) * 1985-03-11 1992-06-17 Teijin Limited E87ag-antigen des pseudomonas aeruginosa, monoklonale antikörper dagegen und hybridom
EP0494085A1 (de) 1985-09-27 1992-07-08 The Regents Of The University Of California Monoklonale Antikörper, die Determinanten von Gram-negativen Bakterien binden
US5179001A (en) * 1985-09-27 1993-01-12 The Regents Of The University Of California Detection and monitoring of chronic and gram-negative infection
US4777136A (en) * 1985-09-27 1988-10-11 The Regents Of The University Of California Monoclonal antibody reactive with Pseudomonas Aeruginosa
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
US4970070A (en) * 1986-02-07 1990-11-13 Genetic Systems Corporation Protective monoclonal antibody compositions for infections due to group B streptococcus
IL81370A (en) * 1986-02-07 1991-06-30 Genetic Systems Corp Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions
ZA87863B (en) * 1986-02-07 1987-09-30 Genetic Systems Corp Cross-protective human monoclonal antibody compositions
ES2009365A6 (es) * 1986-04-24 1989-09-16 Univ California Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas.
GB8610202D0 (en) * 1986-04-25 1986-05-29 Technology Licence Co Ltd Monoclonal antibodies
EP0256713A3 (de) * 1986-08-06 1989-02-15 Merck & Co. Inc. Therapeutische, menschliche Antipseudomonas-Aeruginosa-Antikörper
ZA878610B (en) * 1986-11-20 1989-06-28 Minnesota Mining & Mfg Method for the evaluation of oral microbes
US5521085A (en) * 1986-12-15 1996-05-28 Mitsui Toatsu Chemicals, Inc. Transformed cell lines producing human monoclonal antibodies specific for Pseudomonas aeruginosa serotypes
AU1807188A (en) * 1987-04-10 1988-11-04 Xoma Corporation Human monoclonal antibodies binding determinants of gram negative bacteria
ES2045027T3 (es) * 1987-08-10 1994-01-16 Miles Inc Igm purificadas.
JPH01197500A (ja) * 1988-01-29 1989-08-09 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
GB2218703B (en) * 1988-05-10 1992-10-28 Sumitomo Chemical Co Human monoclonal antibody to p.aeruginosa: its production and use
US5439665A (en) * 1988-07-29 1995-08-08 Immunomedics Detection and treatment of infectious and inflammatory lesions
CA1341375C (en) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions and methods for the treatment and prevention of gram-negative bacterial infections
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process
JPH02283294A (ja) * 1989-04-24 1990-11-20 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
US5233024A (en) * 1991-04-09 1993-08-03 The Brigham & Women's Hospital Anti-idiotypic monoclonal antibodies for mucoid pseudomonas aeruginosa, their preparation and use
US5824310A (en) * 1991-10-22 1998-10-20 The United States Of America As Represented By The Department Of Health And Human Services Lipopplysaccharide conjugate vaccines
DE69221453T2 (de) * 1991-12-24 1998-02-19 Wako Pure Chem Ind Ltd Verfahren zum Extrahieren von Endotoxinen
US5610031A (en) * 1993-10-27 1997-03-11 The General Hospital Corporation B1k chain of laminin and methods of use
US5562902A (en) * 1994-03-14 1996-10-08 Arp Biomed, Inc. Immunotherapeutic method of treating cancerous diseases by administration of intravenous immunoglobulin
US5807694A (en) * 1995-09-07 1998-09-15 Economic Innovation And Technology Council, University Of Manitoba Detection of salmonella enteritidis and other pathogenic microorganisms and monoclonal antibody useful therefor
US6818222B1 (en) * 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
AU742076B2 (en) * 1997-05-15 2001-12-13 Veritas Therapeutics Inc. Methods of modulating immune coagulation
US6790661B1 (en) 1999-07-16 2004-09-14 Verax Biomedical, Inc. System for detecting bacteria in blood, blood products, and fluids of tissues
EP1269186A2 (de) * 2000-02-15 2003-01-02 Finnish Immunotechnology Ltd. Immunochemische nachweisverfahren oder das gebrauchmachen von mindestens zwei gummi-latex-allergenen
EP1479695B1 (de) * 2003-05-14 2010-02-17 Kenta Biotech AG Humaner monoklonaler Antikörper spezifisch für Lipopolysacchariden (LPS) des Serotyps IATS O6 von Pseudomonas aeruginosa
EP2417157A1 (de) 2009-04-09 2012-02-15 Kenta Biotech AG Für lipopolysaccharide (lps) vom serotyp lats 01 aus pseudomonas aeruginosa spezifischer humaner monoklonaler antikörper
JP2013520159A (ja) * 2010-02-18 2013-06-06 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 緑膿菌の血清型ｅ型リポ多糖に対する抗体
EP2361989A1 (de) * 2010-02-26 2011-08-31 Kenta Biotech AG Verfahren und Kits zur Serotypisierung von Pseudomonas aeruginosa und Oligonukleotidsequenzen zur Verwendung in solchen Methoden und Kits

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO820248L (no) * 1981-01-28 1982-07-29 Coats Patons Plc Fremgangsmaate ved fremstilling av monoklone antistoffer og celler istand til aa produsere slike antistoffer
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
JPS5929622A (ja) * 1982-08-10 1984-02-16 Meiji Seika Kaisha Ltd モノクロ−ナル抗体、その製造法およびその用途
AU567693B2 (en) * 1982-09-30 1987-12-03 University Of Rochester Human monoclonal antibodies against bacterial toxins
WO1984004458A1 (en) * 1983-05-06 1984-11-22 Matthew Pollack Monoclonal antibodies reactive with endotoxin core
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria

Also Published As

Publication number Publication date
NO852093L (no) 1985-11-26
ES543474A0 (es) 1987-01-16
US4834975A (en) 1989-05-30
FI89278B (fi) 1993-05-31
IE58411B1 (en) 1993-09-22
ZA853888B (en) 1986-01-29
FI852029L (fi) 1985-11-26
GR851234B (de) 1985-07-01
KR850008282A (ko) 1985-12-16
EP0163493B1 (de) 1991-03-27
EP0163493A2 (de) 1985-12-04
AU4285885A (en) 1985-11-28
HU202927B (en) 1991-04-29
ES8702792A1 (es) 1987-01-16
IL75277A (en) 1990-02-09
FI89278C (fi) 1993-09-10
IL75277A0 (en) 1985-09-29
DK233385A (da) 1985-11-26
EP0163493A3 (en) 1986-07-02
NO167758C (no) 1991-12-04
FI852029A0 (fi) 1985-05-21
DK233385D0 (da) 1985-05-24
HUT38123A (en) 1986-04-28
AU600222B2 (en) 1990-08-09
IE851302L (en) 1985-11-25
JPS6169796A (ja) 1986-04-10
DE3582274D1 (de) 1991-05-02
NO167758B (no) 1991-08-26

Similar Documents

Publication Publication Date Title
ATE62021T1 (de) Menschliche monoklonale antikoerper gegen serotypische lipopolysaccharidische determinanten von gram-negativen bakterien und ihre produktion.
SE8605295L (sv) Monoklonala antikroppar som er korsreaktiva och korsprotektiva mot p. aeruginosa-sero-typer
NO162613C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive diarylacetylener.
ATE99358T1 (de) Alpha-1-antitrypsinmutante und dafuer kodierende dns und herstellung derselben, und solche mutante verwendende therapeutische zusammensetzungen und ihre herstellung.
MX9203403A (es) Carboxilatos heterociclicos 17-aromaticos de 3,20-dioxo-1,4-pregnadieno 17&-ol.
FR2470794A1 (fr) Nouvelles microparticules, leur preparation et leurs applications en biologie, notamment a la culture de cellules diploides humaines
IT8320548A0 (it) Anticorpi aventi doppie specificita', loro preparazione eloro impieghi.
IL112778A0 (en) Substituted heterocycles, their preparation and pharmaceutical compositions containing them
IT1210589B (it) Procedimento per la preparazione dicomposti pirimidinici dotati di attivita' farmacologica particolarmente per il trattamento di infezioni batteriche loro intermedi prodotto ottenuto e composizioni farmaceutiche che li contengono
DE59508864D1 (de) MONOKLONALER ANTIKÖRPER GEGEN CD44v6
BE882162A (fr) Culture thermophile anaerobie productrice d'ethanol
ATE226947T1 (de) 2-substituierte 1,2,5-thiadiazolidin-3-on-1,1- dioxiden, zusammensetzung und deren verwendung
DE3688038D1 (de) Verwendung von buspiron zur herstellung von pharmazeutischen zusammensetzungen zur linderung von krankhaften angst.
IT7926833A0 (it) Procedimento per la fabbricazione "in loco" di elettrodi di carbone.
ATE39694T1 (de) (pyrrol-1-yl)-phenyl-dihydropyridazinone, ihre herstellung und verwendung.
DE59507578D1 (de) Neuer peptidischer wirkstoff und dessen herstellung
RU98104739A (ru) Штамм культивируемых клеток мышиной гибридомы, используемый для получения моноклональных антител к ядрышковому антигену, ассоциированному с клеточной пролиферацией
FR2568585B1 (fr) Nouvelles cellules hybrides secretant des anticorps anti-idiotypiques, nouveaux anticorps monoclonaux secretes par lesdites cellules hybrides, leur preparation et leur application
OA06185A (fr) Nouvelles compositions pharmaceutiques à base d'enzyme bactérien.
ES2112562T3 (es) Nuevo difenilhexeno.
IT8348050A0 (it) Sostanze ss 12538 fisiologicamente attive, loro preparazione e microorganismo che le produce
IT8219456A0 (it) Composto ad attivita'analgesica e antiinfiammatoria ad azione protratta, procedimento per la sua preparazione e relative composizioni farmaceutiche.
ATE38666T1 (de) Diaminopyrimidine und deren herstellung.
ES8201133A1 (es) Un procedimiento para la produccion de 1-(1-metiletil)amino-3-(4-alquiltio)-1-naftalenil-oxi-2-propanol.
RO87440A2 (ro) Soi de ardei lung(capsicum annuum l.var longum)"cosmin"

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
RZN Patent revoked
RZN Patent revoked