ES2009140A6 - Un metodo de produccion de anticuerpos monoclonales humanos de proteccion cruzada y de composiciones que los contienen. - Google Patents

Un metodo de produccion de anticuerpos monoclonales humanos de proteccion cruzada y de composiciones que los contienen.

Info

Publication number
ES2009140A6
ES2009140A6 ES8700289A ES8700289A ES2009140A6 ES 2009140 A6 ES2009140 A6 ES 2009140A6 ES 8700289 A ES8700289 A ES 8700289A ES 8700289 A ES8700289 A ES 8700289A ES 2009140 A6 ES2009140 A6 ES 2009140A6
Authority
ES
Spain
Prior art keywords
crl
human monoclonal
antibodies
cross
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700289A
Other languages
English (en)
Inventor
Howard V Raff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetic Systems Corp
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of ES2009140A6 publication Critical patent/ES2009140A6/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN METODO DE PRODUCCION DE ANTICUERPOS MONOCLONALES HUMANOS DE PROTECCION CRUZADA Y DE COMPOSICIONES QUE LOS CONTIENEN. LOS ANTICUERPOS SE OBTIENEN MEDIANTE EL CULTIVO DE LINEAS CELULARES QUE SEGREGAN ANTICUERPOS MONOCLONALES HUMANOS CAPACES DE UNIRSE A MOLECULAS DE DIFERENTES ESPECIES BACTERIANAS Y SU POSTERIOR RECUPERACION. LOS ANTICUERPOS ASI OBTENIDOS PUEDEN FORMULARSE EN COMPOSICIONES FARMACEUTICAS EN COMBINACION CON OTROS ANTICUERPOS, FRACCIONES DE PLASMA O AGENTES ANTIMICROBIANOS. LOS ANTICUERPOS MONOCLONALES ASI OBTENIDOS PROTEGEN CONTRA LOS ATAQUES LETALES DE DIVERSOS GENEROS DE BACTERIAS.
ES8700289A 1986-02-07 1987-02-06 Un metodo de produccion de anticuerpos monoclonales humanos de proteccion cruzada y de composiciones que los contienen. Expired ES2009140A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82800586A 1986-02-07 1986-02-07
US94449586A 1986-12-19 1986-12-19

Publications (1)

Publication Number Publication Date
ES2009140A6 true ES2009140A6 (es) 1989-09-01

Family

ID=27125154

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8700289A Expired ES2009140A6 (es) 1986-02-07 1987-02-06 Un metodo de produccion de anticuerpos monoclonales humanos de proteccion cruzada y de composiciones que los contienen.

Country Status (28)

Country Link
US (2) US5717071A (es)
JP (1) JP2645343B2 (es)
KR (1) KR870007697A (es)
CN (1) CN87102167A (es)
AT (1) AT398781B (es)
BE (1) BE1000967A5 (es)
CA (1) CA1339013C (es)
CH (1) CH672072A5 (es)
DE (1) DE3703711A1 (es)
DK (1) DK63187A (es)
ES (1) ES2009140A6 (es)
FI (1) FI94489C (es)
FR (1) FR2595946B1 (es)
GB (1) GB2186592B (es)
GR (1) GR870194B (es)
HK (1) HK21795A (es)
HU (1) HU203583B (es)
IE (1) IE59627B1 (es)
IL (1) IL81370A (es)
IT (1) IT1207589B (es)
LU (1) LU86761A1 (es)
MX (1) MX9203629A (es)
NL (1) NL8700286A (es)
NO (1) NO176924C (es)
NZ (2) NZ219187A (es)
OA (1) OA08477A (es)
PT (1) PT84258B (es)
SE (1) SE468747B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0256713A3 (en) * 1986-08-06 1989-02-15 Merck & Co. Inc. Therapeutic human antipseudomonas aeruginosa antibodies
CA1341375C (en) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions and methods for the treatment and prevention of gram-negative bacterial infections
DE3925161A1 (de) * 1989-03-15 1990-09-27 Boehringer Mannheim Gmbh Monoklonale, gegen eca gerichtete antikoerper und ihre verwendung
JPH0329196A (ja) * 1989-05-09 1991-02-07 Advanced Micro Devicds Inc センス増幅器
US6315999B1 (en) 1989-08-10 2001-11-13 Solvay, S.A. Pharmaceutical product for the treatment of sepsis
GB8918232D0 (en) * 1989-08-10 1989-09-20 Opal Stephen M Pharmaceutical product for the treatment of septic shock
US20080139789A1 (en) * 1990-10-22 2008-06-12 Henry M. Jackson Foundation For The Advancement Of Military Medicine Isolated Broadly Reactive Opsonic Immunoglobulin for Treating a Pathogenic Coagulase-Negative Staphylococcus Infection
EP0635132B2 (en) * 1992-03-19 2008-05-14 Henry M. Jackson Foundation For The Advancement Of Military Medicine Broadly reactive opsonic antibodies that react with common staphylococcal antigens
CA2153661A1 (en) * 1993-01-12 1994-07-21 Anthony George Gristina Methods and compositions for the direct concentrated delivery of passive immunity
US5510264A (en) * 1993-09-28 1996-04-23 Insight Biotech Inc. Antibodies which bind meningitis related homologous antigenic sequences
ATE474849T1 (de) * 1998-04-14 2010-08-15 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein
CA2694466A1 (en) * 2007-07-23 2009-01-29 Sanofi Pasteur Limited Immunogenic polypeptides and monoclonal antibodies
US8444983B2 (en) * 2009-03-23 2013-05-21 Quark Pharmaceuticals, Inc. Composition of anti-ENDO180 antibodies and methods of use for the treatment of cancer and fibrotic diseases
BR112013013702A2 (pt) 2010-12-03 2016-09-13 Sanofi Pasteur Ltd composição para imunização contra streptococcus pneumoniae
US11168131B2 (en) 2015-11-10 2021-11-09 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
KR102697723B1 (ko) 2017-01-18 2024-08-21 비스테라, 인크. 항체 분자-약물 접합체 및 이의 용도
WO2021203024A1 (en) 2020-04-03 2021-10-07 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
CA1262238C (en) * 1982-09-30 1989-10-10 HUMAN MONOCLONAL ANTIBODIES AGAINST BACTERIAL TOXINS
US4587121A (en) * 1983-06-14 1986-05-06 Miles Laboratories, Inc. High titer Pseudomonas immune serum globulin
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
US4834975A (en) * 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
DE3426903A1 (de) * 1984-07-20 1986-01-23 Biotest Pharma GmbH, 6000 Frankfurt Eine immunglobulinpraeparation in kombination mit einer anderen pharmakologisch wirksamen praeparation zur verwendung bei der behandlung von krankheiten
US4675287A (en) * 1984-07-26 1987-06-23 Scripps Clinic And Research Foundation Monoclonal antibody directed to human ganglioside GD2
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
US4772464A (en) * 1985-08-01 1988-09-20 Miles Laboratories, Inc. Protective antibodies to serotypic determinants of flagellar antigens
US4777136A (en) * 1985-09-27 1988-10-11 The Regents Of The University Of California Monoclonal antibody reactive with Pseudomonas Aeruginosa
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
US4970070A (en) * 1986-02-07 1990-11-13 Genetic Systems Corporation Protective monoclonal antibody compositions for infections due to group B streptococcus

Also Published As

Publication number Publication date
IE870320L (en) 1987-08-07
NZ219187A (en) 1990-12-21
NO870476D0 (no) 1987-02-06
CN87102167A (zh) 1988-02-03
FI94489C (fi) 1995-09-25
HUT46062A (en) 1988-09-28
PT84258A (en) 1987-03-01
NO176924C (no) 1995-06-21
FI94489B (fi) 1995-06-15
IL81370A (en) 1991-06-30
IL81370A0 (en) 1987-08-31
HK21795A (en) 1995-02-24
FR2595946A1 (fr) 1987-09-25
DE3703711A1 (de) 1987-09-24
US5837541A (en) 1998-11-17
JPS62270535A (ja) 1987-11-24
CA1339013C (en) 1997-03-25
CH672072A5 (es) 1989-10-31
DK63187D0 (da) 1987-02-06
LU86761A1 (fr) 1987-09-15
DK63187A (da) 1987-08-08
NZ233920A (en) 1990-12-21
DE3703711C2 (es) 1993-06-24
IE59627B1 (en) 1994-03-09
IT1207589B (it) 1989-05-25
SE8700467D0 (sv) 1987-02-06
NL8700286A (nl) 1987-09-01
GB2186592B (en) 1990-08-01
KR870007697A (ko) 1987-09-21
NO870476L (no) 1987-08-10
HU203583B (en) 1991-08-28
GB8702689D0 (en) 1987-03-11
FI870502A (fi) 1987-08-08
JP2645343B2 (ja) 1997-08-25
GB2186592A (en) 1987-08-19
FR2595946B1 (fr) 1991-10-04
OA08477A (fr) 1988-07-29
ATA26287A (de) 1994-06-15
IT8719292A0 (it) 1987-02-06
BE1000967A5 (fr) 1989-05-30
SE8700467L (sv) 1987-08-08
GR870194B (en) 1987-06-10
MX9203629A (es) 1992-07-01
AT398781B (de) 1995-01-25
SE468747B (sv) 1993-03-15
FI870502A0 (fi) 1987-02-06
PT84258B (pt) 1989-09-14
NO176924B (no) 1995-03-13
US5717071A (en) 1998-02-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020401