IL73822A - Method of resolving bicyclic imino-carboxylic acid ester racemates,and novel intermediates therefor - Google Patents

Method of resolving bicyclic imino-carboxylic acid ester racemates,and novel intermediates therefor

Info

Publication number
IL73822A
IL73822A IL73822A IL7382284A IL73822A IL 73822 A IL73822 A IL 73822A IL 73822 A IL73822 A IL 73822A IL 7382284 A IL7382284 A IL 7382284A IL 73822 A IL73822 A IL 73822A
Authority
IL
Israel
Prior art keywords
carboxylic acid
resolving
formula
acid ester
diastereoisomeric
Prior art date
Application number
IL73822A
Other languages
English (en)
Other versions
IL73822A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL73822A0 publication Critical patent/IL73822A0/xx
Publication of IL73822A publication Critical patent/IL73822A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL73822A 1983-12-15 1984-12-14 Method of resolving bicyclic imino-carboxylic acid ester racemates,and novel intermediates therefor IL73822A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833345355 DE3345355A1 (de) 1983-12-15 1983-12-15 Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester

Publications (2)

Publication Number Publication Date
IL73822A0 IL73822A0 (en) 1985-03-31
IL73822A true IL73822A (en) 1989-02-28

Family

ID=6216990

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73822A IL73822A (en) 1983-12-15 1984-12-14 Method of resolving bicyclic imino-carboxylic acid ester racemates,and novel intermediates therefor

Country Status (15)

Country Link
US (1) US4659838A (fr)
EP (1) EP0146080B1 (fr)
JP (2) JPH062734B2 (fr)
KR (1) KR910009935B1 (fr)
AT (1) ATE44953T1 (fr)
CA (1) CA1232910A (fr)
DE (2) DE3345355A1 (fr)
DK (1) DK163819C (fr)
ES (1) ES538556A0 (fr)
FI (1) FI81783C (fr)
GR (1) GR82456B (fr)
HU (1) HU195952B (fr)
IE (1) IE57752B1 (fr)
IL (1) IL73822A (fr)
PT (1) PT79669B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
IE55867B1 (en) * 1981-12-29 1991-02-14 Hoechst Ag New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
GB0216416D0 (en) * 2002-07-15 2002-08-21 Novartis Ag Organic compounds
WO2004092132A1 (fr) * 2003-04-15 2004-10-28 Warner-Lambert Company Llc Derives bicycliques [b]-fusionnes de proline et leur utilisation pour traiter des etats arthritiques
MXPA05010165A (es) * 2003-04-15 2005-11-16 Warner Lambert Co Derivados de prolina biciclicos [c]-condensados y su uso para el tratamiento de estados artriticos.
JP5247466B2 (ja) * 2005-12-22 2013-07-24 メルク・シャープ・アンド・ドーム・コーポレーション ６，６−ジメチル−３−アザビシクロ−［３．１．０］−ヘキサン化合物およびその鏡像異性体塩を調製するプロセス
ES2537759T3 (es) * 2006-06-19 2015-06-11 Merck Patent Gmbh Compuestos enriquecidos enantioméricamente y proceso
WO2011133651A1 (fr) * 2010-04-20 2011-10-27 Chiral Quest , Inc. Procédé énantiosélectif de production de cycloalcénylalanines bêta-substituées

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880866A (en) * 1972-05-01 1975-04-29 American Home Prod 7-Azaindole fused heterocyclic compounds
JPS50101355A (fr) * 1974-01-17 1975-08-11
SU573480A1 (ru) * 1976-01-12 1977-09-25 Предприятие П/Я М-5043 Способ получени -пролина
JPS5346967A (en) * 1976-10-08 1978-04-27 Kyowa Hakko Kogyo Co Ltd R-2-(beta-halogenoethyl)-1-methyl-pyrrolidine
US4111951A (en) * 1977-01-17 1978-09-05 Hoffmann-La Roche Inc. Process for L-3,4-dehydroproline
YU93877A (en) * 1977-04-08 1982-06-30 Krka Process for the resolution of racemic alpha-aminonitrils
CA1117127A (fr) * 1978-06-27 1982-01-26 Janet A. Day Derives du 3-azabicyclo(3.1.0)hexane et methode de preparation
ZA811493B (en) * 1980-04-02 1982-03-31 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
HU191120B (en) * 1983-01-31 1987-01-28 Hoechts Ag,De Process for raceme separation of optically active byciclic imino-alpha-carbonic acid esthers

Also Published As

Publication number Publication date
PT79669B (de) 1986-11-24
ES8601884A1 (es) 1985-11-01
DE3345355A1 (de) 1985-06-27
IE843222L (en) 1985-06-15
DK602084A (da) 1985-06-16
JPH06312977A (ja) 1994-11-08
DK163819B (da) 1992-04-06
KR910009935B1 (ko) 1991-12-06
DE3479118D1 (en) 1989-08-31
GR82456B (en) 1985-04-08
ES538556A0 (es) 1985-11-01
EP0146080A2 (fr) 1985-06-26
PT79669A (de) 1985-01-01
DK163819C (da) 1992-09-07
EP0146080B1 (fr) 1989-07-26
JPH062734B2 (ja) 1994-01-12
FI844929A0 (fi) 1984-12-13
HUT39427A (en) 1986-09-29
JPH0723359B2 (ja) 1995-03-15
DK602084D0 (da) 1984-12-14
CA1232910A (fr) 1988-02-16
US4659838A (en) 1987-04-21
EP0146080A3 (en) 1985-08-07
FI81783B (fi) 1990-08-31
FI81783C (fi) 1990-12-10
IL73822A0 (en) 1985-03-31
KR850004461A (ko) 1985-07-15
ATE44953T1 (de) 1989-08-15
IE57752B1 (en) 1993-03-24
HU195952B (en) 1988-08-29
JPS60146871A (ja) 1985-08-02
FI844929L (fi) 1985-06-16

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Legal Events

Date Code Title Description
KB Patent renewed
HP Change in proprietorship
KB Patent renewed
EXP Patent expired