CA1328881C
(fr)
*
|
1984-12-21 |
1994-04-26 |
Pierre Barbier |
Procede pour la fabrication d'oxetanones
|
ZA859574B
(en)
*
|
1984-12-21 |
1986-08-27 |
Hoffmann La Roche |
Process for the manufacture of oxetanones
|
CA1270837A
(fr)
*
|
1984-12-21 |
1990-06-26 |
Hoffmann-La Roche Limited |
Oxetanones
|
JPH0618793Y2
(ja)
*
|
1986-06-13 |
1994-05-18 |
パイオニア株式会社 |
作業台
|
US4806564A
(en)
*
|
1987-05-26 |
1989-02-21 |
Merck & Co., Inc. |
Antihypercholesterolemic beta-lactones
|
US4816477A
(en)
*
|
1987-05-26 |
1989-03-28 |
Merck & Co., Inc. |
Antihypercholesterolemic β-lactones
|
US5063210A
(en)
*
|
1989-04-20 |
1991-11-05 |
Lange Iii Louis G |
Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
|
US5017565A
(en)
*
|
1989-04-20 |
1991-05-21 |
Lange Iii Louis G |
Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
|
US5484777A
(en)
*
|
1989-04-20 |
1996-01-16 |
Lange, Iii; Louis G. |
Pancreatic cholesterol esterase inhibitor
|
JP2960947B2
(ja)
*
|
1989-12-25 |
1999-10-12 |
日清製粉株式会社 |
脂質分解酵素阻害剤
|
US5376640A
(en)
*
|
1989-12-25 |
1994-12-27 |
Nisshin Flour Milling Co., Ltd. |
Lipolytic enzyme inhibitors
|
CA2098167C
(fr)
*
|
1992-06-24 |
2006-12-19 |
Dorothea Isler |
Aliments pour humains et animaux contenant un inhibiteur de la lipase
|
CA2128044C
(fr)
*
|
1993-08-05 |
2007-02-20 |
Klaus-Dieter Bremer |
Compositions pharmaceutiques comportant un glucosidase et/ou un inhibiteur d'amylase, et un inhibiteur des lipases
|
US6262277B1
(en)
|
1994-09-13 |
2001-07-17 |
G.D. Searle And Company |
Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
US6268392B1
(en)
|
1994-09-13 |
2001-07-31 |
G. D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
|
US6642268B2
(en)
|
1994-09-13 |
2003-11-04 |
G.D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
|
MY116591A
(en)
*
|
1996-04-26 |
2004-02-28 |
Hoffmann La Roche |
Process for the production of lipstatin and tetrahydrolipstatin
|
KR100479968B1
(ko)
*
|
1997-02-05 |
2005-03-30 |
에프. 호프만-라 로슈 아게 |
위장 리파아제 억제제의 용도
|
US6004996A
(en)
*
|
1997-02-05 |
1999-12-21 |
Hoffman-La Roche Inc. |
Tetrahydrolipstatin containing compositions
|
US7344713B1
(en)
*
|
1997-07-07 |
2008-03-18 |
Pimentel Julio L |
Decreased fat absorption with an anti-lipase antibody
|
GB9727131D0
(en)
*
|
1997-12-24 |
1998-02-25 |
Knoll Ag |
Therapeutic agents
|
US6264937B1
(en)
|
1998-01-09 |
2001-07-24 |
Geltex Pharmaceuticals, Inc. |
Fat-binding polymers
|
US6299868B1
(en)
|
1999-07-14 |
2001-10-09 |
Geltex Pharmaceuticals, Inc. |
Fat-binding polymers
|
US7048917B1
(en)
|
1998-01-09 |
2006-05-23 |
Genzyme Corporation |
Fat-binding polymers
|
ATE263558T1
(de)
*
|
1998-08-14 |
2004-04-15 |
Hoffmann La Roche |
Lipasehemmer und chitosan enthaltende pharmazeutische zusammensetzungen
|
JP3774118B2
(ja)
|
1998-08-14 |
2006-05-10 |
エフ.ホフマン−ラ ロシュ アーゲー |
リパーゼ阻害剤を含む製薬学的組成物
|
ES2200587T3
(es)
|
1998-12-23 |
2004-03-01 |
G.D. Searle Llc |
Combinaciones de inhibidors del transporte de acidos biliares del ileon e inhibidores de la proteina de transferencia de colesteril ester para indicaciones cardiovasculares.
|
EA009466B1
(ru)
|
1998-12-23 |
2007-12-28 |
Джи.Ди. Сирл Ллс |
Ингибитор белка, переносящего эфир холестерила
|
DE69907960T2
(de)
|
1998-12-23 |
2004-02-26 |
G.D. Searle Llc, Chicago |
Kombinationen von ileumgallensäuretransports inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen
|
AU2157400A
(en)
|
1998-12-23 |
2000-07-31 |
G.D. Searle & Co. |
Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
|
JP2002533414A
(ja)
|
1998-12-23 |
2002-10-08 |
ジー.ディー.サール エルエルシー |
心臓血管に適用するための回腸胆汁酸輸送阻害剤および胆汁酸隔離剤の組み合わせ
|
US6569905B1
(en)
|
1998-12-23 |
2003-05-27 |
G.D. Searle, Llc |
Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications
|
WO2000038721A1
(fr)
|
1998-12-23 |
2000-07-06 |
G.D. Searle Llc |
Combinaisons d'inhibiteurs de la proteine de transfert du cholesteryle-ester et de derives de l'acide nicotinique utilisees dans le cadre de troubles cardio-vasculaires
|
ATE228118T1
(de)
*
|
1999-01-29 |
2002-12-15 |
Hoffmann La Roche |
Reinigung von lipstatin
|
EP1196181A1
(fr)
*
|
1999-07-14 |
2002-04-17 |
Geltex Pharmaceuticals, Inc. |
Polymeres fixant la graisse, combines eventuellement avec des inhibiteurs de lipase
|
AR025609A1
(es)
|
1999-09-13 |
2002-12-04 |
Hoffmann La Roche |
Formulaciones lipidas solidas
|
AR025587A1
(es)
*
|
1999-09-13 |
2002-12-04 |
Hoffmann La Roche |
Formulaciones en dispersion que contienen inhibidores de lipasa
|
EP1132389A1
(fr)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
Nouveaux dérivés de l'azaindole pour le traitement de l'obésité
|
EP1286984A2
(fr)
|
2000-03-10 |
2003-03-05 |
Pharmacia Corporation |
Procede de preparation de tetrahydrobenzothiepines
|
EP1142572A1
(fr)
*
|
2000-04-04 |
2001-10-10 |
Volker Dr. Helmstädter |
Composés contenant de l'oxetanon destinés au traitement des maladies intestinales
|
DE10021618A1
(de)
*
|
2000-05-04 |
2001-11-15 |
Volker Helmstaedter |
Präparat für Darmerkrankungen und dessen Verwendung
|
CZ301813B6
(cs)
|
2000-06-27 |
2010-06-30 |
F. Hoffmann-La Roche Ag |
Zpusob prípravy farmaceutické kompozice
|
ES2240516T3
(es)
*
|
2000-07-28 |
2005-10-16 |
F. Hoffmann-La Roche Ag |
Nuevo uso de los inhibidores de lipasa.
|
PL204443B1
(pl)
*
|
2000-07-28 |
2010-01-29 |
Hoffmann La Roche |
Kompozycja farmaceutyczna zawierająca inhibitor lipazy, sposób wytwarzania kompozycji farmaceutycznej, zestaw do leczenia otyłości, zastosowanie kompozycji farmaceutycznej oraz zastosowanie orlistatu i substancji wiążącej kwasy żółciowe
|
CA2417607C
(fr)
*
|
2000-08-09 |
2008-01-29 |
Christine Feinle |
Utilisation d'inhibiteurs de lipase
|
US6900226B2
(en)
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
CA2422698C
(fr)
|
2000-10-16 |
2009-12-15 |
F. Hoffmann-La Roche Ag |
Derives d'indoline et leur utilisation en tant que ligands de recepteur 5-ht2
|
GB0030710D0
(en)
*
|
2000-12-15 |
2001-01-31 |
Hoffmann La Roche |
Piperazine derivatives
|
CA2432085C
(fr)
|
2000-12-27 |
2009-02-24 |
F. Hoffmann-La Roche Ag |
Derives d'indole et leur utilisation en tant que ligands de recepteurs 5-ht2b et 5-ht2c
|
GB0106177D0
(en)
*
|
2001-03-13 |
2001-05-02 |
Hoffmann La Roche |
Piperazine derivatives
|
US20030091610A1
(en)
*
|
2001-03-19 |
2003-05-15 |
The Procter & Gamble Company |
Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
|
US20030072804A1
(en)
*
|
2001-03-19 |
2003-04-17 |
The Procter & Gamble Company |
Use of non-digestible polymeric foams to sequester ingested materials thereby inhibiting their absorption by the body
|
MXPA03010565A
(es)
|
2001-05-21 |
2004-03-02 |
Hoffmann La Roche |
Derivados de quinolina como ligandos para receptor del neuropeptido y.
|
US20030027786A1
(en)
|
2001-06-06 |
2003-02-06 |
Karsten Maeder |
Lipase inhibiting composition
|
US6730319B2
(en)
|
2001-06-06 |
2004-05-04 |
Hoffmann-La Roche Inc. |
Pharmaceutical compositions having depressed melting points
|
US7041280B2
(en)
*
|
2001-06-29 |
2006-05-09 |
Genzyme Corporation |
Aryl boronate functionalized polymers for treating obesity
|
US7049345B2
(en)
*
|
2001-06-29 |
2006-05-23 |
Genzyme Corporation |
Fat-binding polymers
|
PL368994A1
(en)
*
|
2001-08-30 |
2005-04-04 |
Alizyme Therapeutics Limited |
Thieno-(1,3)-oxazin-4-ones with lipase inhibiting activity
|
US6787558B2
(en)
*
|
2001-09-28 |
2004-09-07 |
Hoffmann-La Roche Inc. |
Quinoline derivatives
|
US20070281003A1
(en)
|
2001-10-12 |
2007-12-06 |
Fuisz Richard C |
Polymer-Based Films and Drug Delivery Systems Made Therefrom
|
US8603514B2
(en)
|
2002-04-11 |
2013-12-10 |
Monosol Rx, Llc |
Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
|
US20110033542A1
(en)
|
2009-08-07 |
2011-02-10 |
Monosol Rx, Llc |
Sublingual and buccal film compositions
|
US8765167B2
(en)
|
2001-10-12 |
2014-07-01 |
Monosol Rx, Llc |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
US11207805B2
(en)
|
2001-10-12 |
2021-12-28 |
Aquestive Therapeutics, Inc. |
Process for manufacturing a resulting pharmaceutical film
|
US7357891B2
(en)
|
2001-10-12 |
2008-04-15 |
Monosol Rx, Llc |
Process for making an ingestible film
|
US20190328679A1
(en)
|
2001-10-12 |
2019-10-31 |
Aquestive Therapeutics, Inc. |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
US8900498B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for manufacturing a resulting multi-layer pharmaceutical film
|
US10285910B2
(en)
|
2001-10-12 |
2019-05-14 |
Aquestive Therapeutics, Inc. |
Sublingual and buccal film compositions
|
US8900497B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for making a film having a substantially uniform distribution of components
|
GB0125659D0
(en)
*
|
2001-10-25 |
2001-12-19 |
Ssl Int Plc |
Spermicides
|
US6740663B2
(en)
|
2001-11-02 |
2004-05-25 |
G.D. Searle, Llc |
Mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
|
AU2002362061A1
(en)
*
|
2001-12-04 |
2003-06-17 |
Biogal Gyogyszergyar Rt |
Preparation of orlistat and orlistat crystalline forms
|
AU2002359601A1
(en)
|
2001-12-04 |
2003-06-17 |
Biogal Gyogyszergyar Rt |
A fermentation process for lipstatin and method of extracting lipstatin from a fermentation broth
|
EP1467978A4
(fr)
|
2001-12-20 |
2005-11-02 |
Osi Pharm Inc |
Composes inhibiteurs de la lipase pancreatique, leur synthese et leur utilisation
|
US6852753B2
(en)
|
2002-01-17 |
2005-02-08 |
Pharmacia Corporation |
Alkyl/aryl hydroxy or keto thiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
|
GB0202015D0
(en)
*
|
2002-01-29 |
2002-03-13 |
Hoffmann La Roche |
Piperazine Derivatives
|
PL372295A1
(en)
*
|
2002-02-04 |
2005-07-11 |
F.Hoffmann-La Roche Ag |
Quinoline derivatives as npy antagonists
|
JP2005526732A
(ja)
*
|
2002-02-28 |
2005-09-08 |
エフ.ホフマン−ラ ロシュ アーゲー |
Npy受容体拮抗剤としてのチアゾール誘導体
|
AU2003226370A1
(en)
*
|
2002-04-17 |
2003-11-03 |
The Burnham Institute |
Inhibition of fatty acid synthase by beta-lactones and other compounds for inhibition of cellular proliferation
|
US7728153B2
(en)
*
|
2002-04-17 |
2010-06-01 |
The Burnham Institute For Medical Research |
Method for the asymmetric synthesis of beta-lactone compounds
|
WO2003090742A1
(fr)
*
|
2002-04-26 |
2003-11-06 |
F. Hoffmann-La Roche Ag |
Composition pharmaceutique comportant un inhibiteur des lipases et du glucomannan
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
BR0312461A
(pt)
*
|
2002-07-05 |
2005-04-26 |
Hoffmann La Roche |
Compostos, processo para a preparação de um composto, composição farmacêutica que compreende o mesmo, sua utilização e métodos para tratamento e profilaxia
|
EP1539722A1
(fr)
*
|
2002-08-07 |
2005-06-15 |
F. Hoffmann-La Roche Ag |
Derives de thiazole
|
MXPA05002704A
(es)
*
|
2002-09-12 |
2005-05-05 |
Hoffmann La Roche |
Compuestos de acido n-sustituido-1h-indol-5-propionico como agonistas de los receptores activados proliferadores de peroxisomas (ppar) utiles para el tratamiento de diabetes.
|
ES2312819T3
(es)
*
|
2002-11-25 |
2009-03-01 |
F. Hoffmann-La Roche Ag |
Derivados de indolilo.
|
US8372430B2
(en)
*
|
2002-12-17 |
2013-02-12 |
The Procter & Gamble Company |
Compositions, methods, and kits useful for the alleviation of gastrointestinal effects
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
US20040178058A1
(en)
*
|
2003-03-10 |
2004-09-16 |
Hsueh-Chung Chen |
Electro-chemical deposition apparatus and method of preventing cavities in an ECD copper film
|
EP1457206A1
(fr)
*
|
2003-03-13 |
2004-09-15 |
Fournier Laboratories Ireland Limited |
Utilisation combinée d'un fibrate et de l'orlistat pour le traitement de l'obésité
|
KR20110117731A
(ko)
*
|
2003-05-30 |
2011-10-27 |
랜박시 래보러터리스 리미티드 |
치환된 피롤 유도체와 hmg―co 억제제로서의 이의 용도
|
WO2004113314A1
(fr)
*
|
2003-06-23 |
2004-12-29 |
Biocon Limited |
Nouveaux esters de boronate
|
GB0314967D0
(en)
*
|
2003-06-26 |
2003-07-30 |
Hoffmann La Roche |
Piperazine derivatives
|
US20060025337A1
(en)
*
|
2003-07-01 |
2006-02-02 |
President And Fellows Of Harvard College |
Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
|
AU2003253254A1
(en)
*
|
2003-07-17 |
2005-02-04 |
Biocon Limited |
Preparation of tetrahydrolipstatin by hydrogenation of lipstatin, solvent extraction and purification
|
BRPI0413458A
(pt)
*
|
2003-08-12 |
2006-10-17 |
Hoffmann La Roche |
compostos, processo para a sua preparação, composição farmacêutica que compreende os mesmos, utilização de um composto, métodos para o tratamento e profilaxia de artrite, diabetes, distúrbios alimentares e obesidade
|
ES2297437T3
(es)
*
|
2003-08-12 |
2008-05-01 |
F. Hoffmann-La Roche Ag |
Npy-antagonistas de 2-amino-5-benzoiltiazol.
|
US20050239859A2
(en)
*
|
2003-09-03 |
2005-10-27 |
Solvay Pharmaceuticals Gmbh |
Novel medical uses of 4,5-dihydro-1h-pyrazole derivatives having cb1- antagonistic activity
|
CN1902177A
(zh)
|
2003-09-22 |
2007-01-24 |
万有制药株式会社 |
新哌啶衍生物
|
US20050143441A1
(en)
*
|
2003-10-27 |
2005-06-30 |
Jochen Antel |
Novel medical combination treatment of obesity involving 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity
|
US20050124660A1
(en)
*
|
2003-10-27 |
2005-06-09 |
Jochen Antel |
Novel medical uses of compounds showing CB1-antagonistic activity and combination treatment involving said compounds
|
WO2005051298A2
(fr)
|
2003-11-19 |
2005-06-09 |
Metabasis Therapeutics, Inc. |
Nouvelles substances thyromimetiques contenant du phosphore
|
US8017634B2
(en)
|
2003-12-29 |
2011-09-13 |
President And Fellows Of Harvard College |
Compositions for treating obesity and insulin resistance disorders
|
CA2548671C
(fr)
*
|
2003-12-29 |
2015-02-24 |
President And Fellows Of Harvard College |
Compositions pour traiter ou prevenir l'obesite et les troubles de resistance a l'insuline
|
PL209905B1
(pl)
*
|
2004-01-15 |
2011-11-30 |
Bringwell Internat Ab |
Preparat do leczenia otyłości i związanego z nią syndromu metabolicznego
|
EP2298293A1
(fr)
|
2004-01-16 |
2011-03-23 |
Fuji Oil Company, Limited |
Inhibiteur de lipase
|
US7074822B2
(en)
|
2004-02-23 |
2006-07-11 |
Solvay Pharmaceuticals Gmbh |
Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them
|
EP1734963A4
(fr)
|
2004-04-02 |
2008-06-18 |
Merck & Co Inc |
Methode destinee a traiter des hommes presentant des troubles metaboliques et anthropometriques
|
EP1744772B1
(fr)
|
2004-05-10 |
2017-08-16 |
University of Copenhagen |
Graines de lin permettant de gerer le poids du corps
|
WO2006007851A2
(fr)
*
|
2004-07-19 |
2006-01-26 |
Novo Nordisk A/S |
Inhibition de l'activite du recepteur de la capsaicine dans le traitement de l'obesite ou de maladies et de troubles associe(e)s a l'obesite
|
JP2008517976A
(ja)
|
2004-10-25 |
2008-05-29 |
ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb1カンナビノイド受容体拮抗薬及びカリウムチャンネルオープナーから成る、真性糖尿病1型、肥満及び関連症状の治療用の医薬組成物
|
AP2007003979A0
(en)
*
|
2004-11-23 |
2007-06-30 |
Warner Lambert Co |
7-(2h-pyrazol-3-yl)-3,5-dihyroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for thetreatment of lipidemia
|
US20060246141A1
(en)
*
|
2005-04-12 |
2006-11-02 |
Elan Pharma International, Limited |
Nanoparticulate lipase inhibitor formulations
|
ATE514698T1
(de)
*
|
2005-05-03 |
2011-07-15 |
Hoffmann La Roche |
Tetracyclische azapyrazinoindoline als 5-ht2- liganden
|
RU2417985C2
(ru)
|
2005-05-30 |
2011-05-10 |
Баниу Фармасьютикал Ко., Лтд. |
Новые производные пиперидина
|
WO2006138418A2
(fr)
*
|
2005-06-14 |
2006-12-28 |
President And Fellows Of Harvard College |
Amelioration de la performance cognitive avec des activateurs de sirtuine
|
US20070149466A1
(en)
*
|
2005-07-07 |
2007-06-28 |
Michael Milburn |
Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
|
CA2618112A1
(fr)
|
2005-08-10 |
2007-02-15 |
Banyu Pharmaceutical Co., Ltd. |
Compose de pyridone
|
EP1945635B1
(fr)
*
|
2005-08-18 |
2009-05-06 |
F.Hoffmann-La Roche Ag |
Derives de thiazolyle piperidine utile comme modulateurs du recepteur h3
|
AU2006282260A1
(en)
|
2005-08-24 |
2007-03-01 |
Msd K.K. |
Phenylpyridone derivative
|
EP1939194A4
(fr)
|
2005-09-07 |
2010-12-08 |
Banyu Pharma Co Ltd |
Dérivé de pyridone substitué aromatique bicylique
|
US7355055B2
(en)
*
|
2005-09-08 |
2008-04-08 |
Reliance Life Sciences Pvt. Ltd. |
Compounds for treatment of lipase-mediated diseases
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
WO2007048027A2
(fr)
|
2005-10-21 |
2007-04-26 |
Novartis Ag |
Combinaison de composes organiques
|
AU2006307046A1
(en)
|
2005-10-27 |
2007-05-03 |
Msd K.K. |
Novel benzoxathiin derivative
|
AU2006313430B2
(en)
*
|
2005-11-08 |
2012-09-06 |
Ranbaxy Laboratories Limited |
Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
|
NZ568292A
(en)
|
2005-11-10 |
2011-08-26 |
Msd Kk |
Spiro[cyclohexane-1,1'-(3'H)-4'-azaisobenzofuran]-4-carboxamide derivatives
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
JP4879996B2
(ja)
*
|
2005-11-30 |
2012-02-22 |
エフ.ホフマン−ラ ロシュ アーゲー |
H3調節剤として使用するための1,1−ジオキソ−チオモルホリニルインドリルメタノン誘導体
|
ES2342979T3
(es)
*
|
2005-11-30 |
2010-07-20 |
F. Hoffmann-La Roche Ag |
Derivados de indol-2-carboxamida sustituidos en 5.
|
DE602006020482D1
(de)
*
|
2005-11-30 |
2011-04-14 |
Hoffmann La Roche |
1,5-substituierte indol-2-yl amidderivative
|
ATE448230T1
(de)
*
|
2005-12-09 |
2009-11-15 |
Hoffmann La Roche |
Für die behandlung von obesitas geeignete tricyclische amidderivate
|
AU2006326135A1
(en)
*
|
2005-12-15 |
2007-06-21 |
F. Hoffmann-La Roche Ag |
Pyrrolo[2,3-c]pyridine derivatives
|
CN101331131A
(zh)
*
|
2005-12-16 |
2008-12-24 |
霍夫曼-拉罗奇有限公司 |
用作H3受体调节剂的吡咯并[2,3-b]吡啶衍生物
|
SK22006A3
(sk)
*
|
2006-01-03 |
2007-08-02 |
Biotika, A. S. |
Kmeň Streptomyces toxytricini produkujúci lipstatín a príprava lipstatínu s uvedeným kmeňom
|
US20080021092A1
(en)
*
|
2006-01-06 |
2008-01-24 |
Deepak Murpani |
Stable pharmaceutical compositions of orlistat
|
JP2009523150A
(ja)
*
|
2006-01-13 |
2009-06-18 |
エフ.ホフマン−ラ ロシュ アーゲー |
シクロヘキシルピペラジニルメタノン誘導体及びh3受容体調節剤としてのそれらの使用
|
WO2007082840A1
(fr)
*
|
2006-01-23 |
2007-07-26 |
F. Hoffmann-La Roche Ag |
Dérivés de cyclohexylsulfonamide présentant une activité vis-à-vis des récepteurs h3
|
WO2008020314A2
(fr)
*
|
2006-03-14 |
2008-02-21 |
Ranbaxy Laboratories Limited |
Formulations de dosage stabilisantes à base de statine
|
KR101252635B1
(ko)
|
2006-04-20 |
2013-04-10 |
(주)아모레퍼시픽 |
리파아제 저해제 및 친유성 오일흡수제를 포함하는 약학조성물 및 이로부터 제조된 경구 투여용 제제
|
US7432255B2
(en)
*
|
2006-05-16 |
2008-10-07 |
Hoffmann-La Roche Inc. |
1H-indol-5-yl-piperazin-1-yl-methanone derivatives
|
EP2032554A1
(fr)
*
|
2006-05-30 |
2009-03-11 |
F. Hoffmann-Roche AG |
Dérivés de pipéridinylpyrimidine
|
WO2008010087A2
(fr)
*
|
2006-07-14 |
2008-01-24 |
Ranbaxy Laboratories Limited |
FORMES POLYMORPHES D'UN INHIBITEUR DE LA HMG-CoA-RÉDUCTASE ET LEURS UTILISATIONS
|
US7514433B2
(en)
|
2006-08-03 |
2009-04-07 |
Hoffmann-La Roche Inc. |
1H-indole-6-yl-piperazin-1-yl-methanone derivatives
|
JPWO2008038692A1
(ja)
|
2006-09-28 |
2010-01-28 |
萬有製薬株式会社 |
ジアリールケチミン誘導体
|
AR063275A1
(es)
*
|
2006-10-12 |
2009-01-14 |
Epix Delaware Inc |
Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2.
|
JP5498168B2
(ja)
|
2006-12-01 |
2014-05-21 |
ブリストル−マイヤーズ スクイブ カンパニー |
アテローム性動脈硬化および循環器疾患の治療のためのcetp阻害剤としてのn−((3−ベンジル)−2,2−(ビス−フェニル)−プロパン−1−アミン誘導体
|
US20080146559A1
(en)
|
2006-12-08 |
2008-06-19 |
Li Chen |
4,5,6,7-Tetrahydro-Thieno [2,3-C] Pyridine Derivatives
|
US20080200422A1
(en)
*
|
2007-01-09 |
2008-08-21 |
Cavener Douglas R |
Methods for reduction of adipose tissue mass
|
CA2682727C
(fr)
|
2007-04-02 |
2016-03-22 |
Banyu Pharmaceutical Co., Ltd. |
Derive d'indoledione
|
US20080249156A1
(en)
*
|
2007-04-09 |
2008-10-09 |
Palepu Nageswara R |
Combinations of statins and anti-obesity agent and glitazones
|
AP2009005026A0
(en)
*
|
2007-04-09 |
2009-12-31 |
Scidose Llc |
Combinations of statins and anti-obesity agent
|
JP5616220B2
(ja)
*
|
2007-06-01 |
2014-10-29 |
ザ トラスティーズ オブ プリンストン ユニバーシティ |
宿主細胞代謝経路の調節によるウイルス感染治療
|
MX354786B
(es)
|
2007-06-04 |
2018-03-21 |
Synergy Pharmaceuticals Inc |
Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
KR101504777B1
(ko)
*
|
2007-06-06 |
2015-03-20 |
랜박시 래보러터리스 리미티드 |
오르리스타트의 제조 방법
|
EP2625968A1
(fr)
*
|
2007-09-12 |
2013-08-14 |
Københavns Universitet |
Compositions et procédés pour mieux supprimer la sensation de faim et réduire la digestibilité d'une énergie non grasse et prolonger l'effet de satiété
|
BRPI0817053A2
(pt)
*
|
2007-09-17 |
2015-03-24 |
Reddys Lab Ltd Dr |
Formulações farmacêuticas de orlistat
|
WO2009044380A2
(fr)
|
2007-10-05 |
2009-04-09 |
Ranbaxy Laboratories Limited |
Formulations contenant des particules d'orlistat à dimension de particule contrôlée
|
MX2010004072A
(es)
*
|
2007-10-15 |
2010-09-14 |
Inventis Dds Pvt Ltd |
Composicion farmaceutica de orlistat.
|
US8298583B2
(en)
|
2007-10-19 |
2012-10-30 |
Monosol Rx, Llc |
Film delivery system for tetrahydrolipstatin
|
WO2009076512A1
(fr)
|
2007-12-11 |
2009-06-18 |
Epix Delaware, Inc. |
Composés à base de carboxamide et leur utilisation en tant qu'agonistes du récepteur des chimiokines
|
US20090214682A1
(en)
*
|
2008-02-22 |
2009-08-27 |
Heuer Marvin A |
Composition and methods for weight loss in a subject
|
CA2714617A1
(fr)
|
2008-03-06 |
2009-09-11 |
Banyu Pharmaceutical Co., Ltd. |
Derive d'alkylaminopyridine
|
CA2719581C
(fr)
*
|
2008-03-26 |
2013-11-12 |
Biocon Limited |
Procede de fermentation perfectionne pour obtenir un taux de rendement superieur d'inhibiteur de lipase par rapport a l'acide gras consomme
|
US20110015198A1
(en)
|
2008-03-28 |
2011-01-20 |
Banyu Pharmaceutical Co., Inc. |
Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
|
CA2726917C
(fr)
|
2008-06-04 |
2018-06-26 |
Synergy Pharmaceuticals Inc. |
Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles
|
EP2301936A1
(fr)
|
2008-06-19 |
2011-03-30 |
Banyu Pharmaceutical Co., Ltd. |
Dérivé de spirodiamine-diarylcétoxime
|
EP2141236A1
(fr)
|
2008-07-03 |
2010-01-06 |
KRKA, D.D., Novo Mesto |
Procédé de production de lipstatine et microorganismes correspondant
|
WO2010009319A2
(fr)
|
2008-07-16 |
2010-01-21 |
Synergy Pharmaceuticals Inc. |
Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres
|
EP2319841A1
(fr)
|
2008-07-30 |
2011-05-11 |
Msd K.K. |
Dérivé de cycloalkylamine à noyaux fusionnés à (5 chaînons)-(5 chaînons) ou (5 chaînons) (6 chaînons)
|
WO2010039019A1
(fr)
|
2008-10-03 |
2010-04-08 |
Sigma Alimentos, S.A. De C.V. |
Composition facilitant la régulation du cholestérol total et des lipoprotéines de basse densité (ldl) et/ou la perte de poids et/ou la thermogenèse
|
WO2010042499A1
(fr)
*
|
2008-10-06 |
2010-04-15 |
Banner Pharmacaps, Inc. |
Solutions stables d'orlistat pour formes galéniques pharmaceutiques
|
WO2010043592A1
(fr)
*
|
2008-10-15 |
2010-04-22 |
Revotar Biopharmaceuticals Ag |
Inhibiteurs de la lipase destinés à être utilisés dans le traitement de l’obésité
|
CA2741125A1
(fr)
|
2008-10-22 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
Nouveaux derives de benzimidazole cycliques utiles comme agents anti-diabetiques
|
CN102271509A
(zh)
|
2008-10-31 |
2011-12-07 |
默沙东公司 |
用于抗糖尿病药的新型环苯并咪唑衍生物
|
US20120046364A1
(en)
|
2009-02-10 |
2012-02-23 |
Metabasis Therapeutics, Inc. |
Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
|
WO2010093243A1
(fr)
|
2009-02-12 |
2010-08-19 |
Coöperatieve Mirzorg U.A., Arnhem |
Utilisation d'une combinaison de diazoxyde et de metformine pour le traitement de l'obésité ou des troubles liés à l'obésité
|
US20100215635A1
(en)
*
|
2009-02-23 |
2010-08-26 |
Zoltan Kiss |
Small molecules to induce weight loss or to reduce weight gain
|
WO2010112569A1
(fr)
|
2009-03-31 |
2010-10-07 |
Robert Zimmermann |
Modulation de lipase de triglycérides d'adipose pour la prévention et le traitement d'une cachexie, d'une perte de poids et d'une atrophie musculaire et procédés de criblage s'y rapportant
|
EP2414830A2
(fr)
|
2009-03-31 |
2012-02-08 |
Robert Zimmermann |
Modulation de l'adipose triglycéride lipase pour prévenir et traiter la cachexie, la perte de poids et l'atrophie musculaire et procédés de criblage à des fins d'identification
|
BRPI0901602B8
(pt)
|
2009-04-03 |
2021-05-25 |
Ems S/A |
formulação farmacêuticas
|
EP2473515A4
(fr)
|
2009-09-04 |
2013-11-27 |
Univ Toledo |
Procédés de fabrication de bêta-lactones optiquement pures à partir d'aldéhydes et compositions obtenues par ces procédés
|
JP5696156B2
(ja)
|
2009-11-02 |
2015-04-08 |
ファイザー・インク |
ジオキサ−ビシクロ[3.2.1]オクタン−2,3,4−トリオール誘導体
|
UA107369C2
(en)
|
2010-02-01 |
2014-12-25 |
Lab Bago S A |
Pharmaceutical composition with anti-obesity activity comprising a premixture of pure orlistat and preparation process
|
US8524909B2
(en)
|
2010-02-02 |
2013-09-03 |
Hoffmann-La Roche Inc. |
Tetrahydro-pyran derivatives
|
US8895596B2
(en)
|
2010-02-25 |
2014-11-25 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
US8450350B2
(en)
|
2010-05-05 |
2013-05-28 |
Infinity Pharmaceuticals, Inc. |
Triazoles as inhibitors of fatty acid synthase
|
WO2011140190A1
(fr)
|
2010-05-05 |
2011-11-10 |
Infinity Pharmaceuticals |
Tétrazolones utilisés en tant qu'inhibiteurs d'acide gras synthase (fasn)
|
JP2013528172A
(ja)
|
2010-05-21 |
2013-07-08 |
ファイザー・インク |
2−フェニルベンゾイルアミド
|
US9237762B2
(en)
|
2010-05-24 |
2016-01-19 |
Swedish Oat Fiber Ab |
Aqueous dispersion comprising galactolipids and method for production thereof
|
EP2392327A1
(fr)
|
2010-06-04 |
2011-12-07 |
Universitätsmedizin der Johannes Gutenberg-Universität Mainz |
Utilisation d'orlistat pour le traitement antiparasite d'une maladie de parasite
|
BR112013000296A2
(pt)
|
2010-07-06 |
2019-09-24 |
Astrazeneca Ab |
agentes terapêuticos 976
|
CN101885713B
(zh)
*
|
2010-07-19 |
2011-11-30 |
大邦(湖南)生物制药有限公司 |
一种毒三素链霉菌发酵液中分离提取利普司他汀的工艺
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
CN101948450B
(zh)
*
|
2010-10-13 |
2013-04-24 |
鲁南制药集团股份有限公司 |
一种生产制备奥利司他的方法
|
US9149959B2
(en)
|
2010-10-22 |
2015-10-06 |
Monosol Rx, Llc |
Manufacturing of small film strips
|
MX345040B
(es)
|
2010-11-08 |
2017-01-16 |
Albireo Ab |
Una combinacion farmaceutica que comprende un inhibidor de ibat y un aglutinante de acido biliar.
|
RS60901B1
(sr)
|
2010-11-08 |
2020-11-30 |
Albireo Ab |
Ibat inhibitori za lečenje oboljenja jetre
|
EP2677869B1
(fr)
|
2011-02-25 |
2017-11-08 |
Merck Sharp & Dohme Corp. |
Nouveaux dérivés d'azabenzimidazole cyclique utiles en tant qu'agents antidiabétiques
|
JP2014513923A
(ja)
|
2011-03-04 |
2014-06-19 |
ファイザー・インク |
Edn3様ペプチドおよびその使用
|
CN102304105B
(zh)
*
|
2011-07-15 |
2013-07-10 |
鲁南新时代生物技术有限公司 |
一种制备高纯度奥利司他的方法
|
UY34194A
(es)
|
2011-07-15 |
2013-02-28 |
Astrazeneca Ab |
?(3-(4-(espiroheterocíclico)metil)fenoxi)azetidin-1-il)(5-(fenil)-1,3,4-oxadiazol-2-il)metanona en el tratamiento de la obesidad?
|
CN103030613B
(zh)
*
|
2011-09-29 |
2014-11-12 |
北大方正集团有限公司 |
一种利普司他汀的提纯方法
|
JP2013249293A
(ja)
*
|
2012-06-04 |
2013-12-12 |
Kao Corp |
リパーゼ活性阻害剤、抗真菌剤、及びフケ抑制剤
|
CA2880901A1
(fr)
|
2012-08-02 |
2014-02-06 |
Merck Sharp & Dohme Corp. |
Composes tricycliques antidiabetiques
|
WO2014060445A1
(fr)
|
2012-10-19 |
2014-04-24 |
Akzo Nobel Chemicals International B.V. |
Procédé de préparation d'orlistat à haut degré de pureté
|
CN102936234B
(zh)
*
|
2012-11-15 |
2015-04-01 |
江苏阿尔法药业有限公司 |
一种制备脂肪酶抑制剂奥利司他的方法
|
CN102993134B
(zh)
*
|
2012-12-31 |
2015-08-05 |
鲁南新时代生物技术有限公司 |
一种利普司他汀的提纯方法
|
WO2014130608A1
(fr)
|
2013-02-22 |
2014-08-28 |
Merck Sharp & Dohme Corp. |
Composés bicycliques antidiabétiques
|
EP2970119B1
(fr)
|
2013-03-14 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Nouveaux dérivés d'indole utiles en tant qu'agents antidiabétiques
|
EP2970384A1
(fr)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Agonistes de la guanylate cyclase et leurs utilisations
|
WO2014151200A2
(fr)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions utiles pour le traitement de troubles gastro-intestinaux
|
EP2986599A1
(fr)
|
2013-04-17 |
2016-02-24 |
Pfizer Inc. |
Dérivés de n-pipéridin-3-ylbenzamide dans le traitement des maladies cardiovasculaires
|
JP6606491B2
(ja)
|
2013-06-05 |
2019-11-13 |
シナジー ファーマシューティカルズ インコーポレイテッド |
グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法
|
WO2015051496A1
(fr)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Composés tricycliques antidiabétiques
|
DK3186242T3
(da)
|
2014-08-29 |
2021-12-20 |
Tes Pharma S R L |
Alfa-amino-beta-carboxymuconsyre-semialdehyd-decarboxylasehæmmere
|
US10743813B2
(en)
|
2014-09-11 |
2020-08-18 |
Rattan Nath |
Diabetes control using postprandial feedback
|
WO2016055901A1
(fr)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Composés d'amide substitué
|
JP2019519487A
(ja)
|
2016-05-05 |
2019-07-11 |
アクエスティブ セラピューティクス インコーポレイテッド |
送達増強エピネフリン組成物
|
US11273131B2
(en)
|
2016-05-05 |
2022-03-15 |
Aquestive Therapeutics, Inc. |
Pharmaceutical compositions with enhanced permeation
|
AR109950A1
(es)
|
2016-10-14 |
2019-02-06 |
Tes Pharma S R L |
INHIBIDORES DE LA ÁCIDO a-AMINO-b-CARBOXIMUCÓNICO SEMIALDEHÍDO DESCARBOXILASA
|
EP3551176A4
(fr)
|
2016-12-06 |
2020-06-24 |
Merck Sharp & Dohme Corp. |
Composés hétérocycliques antidiabétiques
|
WO2018118670A1
(fr)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Composés de spirochromane antidiabétiques
|
KR20210111248A
(ko)
|
2018-11-20 |
2021-09-10 |
테스 파마 에스.알.엘. |
α-아미노-β-카르복시뮤콘산 세미알데하이드 데카르복실라제의 저해제
|
BR112021013807A2
(pt)
|
2019-01-18 |
2021-11-30 |
Astrazeneca Ab |
Inibidores de pcsk9 e seus métodos de uso
|
NL2022615B1
(en)
|
2019-02-21 |
2020-08-31 |
Patrick Alexander Unger |
Pharmaceutical composition comprising tetrahydrocannabivarin for the prevention and treatment of overweight
|
JPWO2021157619A1
(fr)
|
2020-02-05 |
2021-08-12 |
|
|