AU2003253254A1 - Preparation of tetrahydrolipstatin by hydrogenation of lipstatin, solvent extraction and purification - Google Patents

Preparation of tetrahydrolipstatin by hydrogenation of lipstatin, solvent extraction and purification

Info

Publication number
AU2003253254A1
AU2003253254A1 AU2003253254A AU2003253254A AU2003253254A1 AU 2003253254 A1 AU2003253254 A1 AU 2003253254A1 AU 2003253254 A AU2003253254 A AU 2003253254A AU 2003253254 A AU2003253254 A AU 2003253254A AU 2003253254 A1 AU2003253254 A1 AU 2003253254A1
Authority
AU
Australia
Prior art keywords
lipstatin
tetrahydrolipstatin
hydrogenation
purification
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003253254A
Inventor
Sambasivam Ganesh
Joy Mathew
Tom Thomas Puthiaparampil
Kumar Veeranna Vijaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocon Ltd
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Publication of AU2003253254A1 publication Critical patent/AU2003253254A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2003253254A 2003-07-17 2003-07-17 Preparation of tetrahydrolipstatin by hydrogenation of lipstatin, solvent extraction and purification Abandoned AU2003253254A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2003/000243 WO2005007639A1 (en) 2003-07-17 2003-07-17 Preparation of tetrahydrolipstatin by hydrogenation of lipstatin, solvent extraction and purification

Publications (1)

Publication Number Publication Date
AU2003253254A1 true AU2003253254A1 (en) 2005-02-04

Family

ID=34074044

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003253254A Abandoned AU2003253254A1 (en) 2003-07-17 2003-07-17 Preparation of tetrahydrolipstatin by hydrogenation of lipstatin, solvent extraction and purification

Country Status (2)

Country Link
AU (1) AU2003253254A1 (en)
WO (1) WO2005007639A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1763021B (en) * 2005-09-29 2010-08-11 杭州华东医药集团生物工程研究所有限公司 Method for purifying orlistat
WO2009040827A1 (en) * 2007-09-24 2009-04-02 Biocon Limited A process for obtaining tetrahydrolipstatin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247547A (en) * 1983-06-22 1988-12-28 Paul Hadvary Leucine derivatives
MY116591A (en) * 1996-04-26 2004-02-28 Hoffmann La Roche Process for the production of lipstatin and tetrahydrolipstatin
DK1028115T3 (en) * 1999-01-29 2003-03-17 Hoffmann La Roche Purification of lipstatin

Also Published As

Publication number Publication date
WO2005007639A1 (en) 2005-01-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase