IL71734A - Pyridyl carboxylic acid ester n-oxides,process for their preparation and pharmaceutical compositions comprising them - Google Patents

Pyridyl carboxylic acid ester n-oxides,process for their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL71734A
IL71734A IL71734A IL7173484A IL71734A IL 71734 A IL71734 A IL 71734A IL 71734 A IL71734 A IL 71734A IL 7173484 A IL7173484 A IL 7173484A IL 71734 A IL71734 A IL 71734A
Authority
IL
Israel
Prior art keywords
oxides
preparation
carboxylic acid
acid ester
pharmaceutical compositions
Prior art date
Application number
IL71734A
Other languages
English (en)
Other versions
IL71734A0 (en
Original Assignee
Merz & Co Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz & Co Gmbh & Co filed Critical Merz & Co Gmbh & Co
Publication of IL71734A0 publication Critical patent/IL71734A0/xx
Publication of IL71734A publication Critical patent/IL71734A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL71734A 1983-05-02 1984-05-02 Pyridyl carboxylic acid ester n-oxides,process for their preparation and pharmaceutical compositions comprising them IL71734A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833315877 DE3315877A1 (de) 1983-05-02 1983-05-02 N-oxide von pyridyl-carbonsaeureestern, ein verfahren zu ihrer herstellung und pharmazeutische mittel, die diese verbindungen enthalten

Publications (2)

Publication Number Publication Date
IL71734A0 IL71734A0 (en) 1984-09-30
IL71734A true IL71734A (en) 1988-02-29

Family

ID=6197884

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71734A IL71734A (en) 1983-05-02 1984-05-02 Pyridyl carboxylic acid ester n-oxides,process for their preparation and pharmaceutical compositions comprising them

Country Status (24)

Country Link
US (1) US4758581A (fr)
JP (1) JPS59206357A (fr)
KR (1) KR860001907B1 (fr)
AU (1) AU564780B2 (fr)
BE (1) BE899558A (fr)
CA (1) CA1247092A (fr)
CH (1) CH660005A5 (fr)
CS (1) CS241082B2 (fr)
DE (1) DE3315877A1 (fr)
DK (1) DK159105C (fr)
ES (1) ES8503660A1 (fr)
FI (1) FI80444C (fr)
FR (1) FR2545486B1 (fr)
GB (1) GB2139621B (fr)
GR (1) GR79862B (fr)
HU (1) HU191681B (fr)
IE (1) IE57393B1 (fr)
IL (1) IL71734A (fr)
IT (1) IT1206144B (fr)
LU (1) LU85344A1 (fr)
NL (1) NL8401357A (fr)
SE (1) SE454986B (fr)
YU (1) YU45900B (fr)
ZA (1) ZA843278B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1256M (fr) * 1961-06-26 1962-04-16 M I P Soc Amilloise De Prod Ch Médicament hypocholésterolémiant a base de n-oxyde de l'acide nicotinique.
GB1213162A (en) * 1966-11-16 1970-11-18 Astra Ab Serum lipid lowering pyridine derivatives and their preparation
AT291853B (de) * 1967-03-22 1971-08-10 Buero Patent Ag Automatische, gleislose Förderanlage
DE3009099A1 (de) * 1980-03-10 1981-09-17 Merz + Co GmbH & Co, 6000 Frankfurt Neue phenylester der nikotinsaeure und verfahren zu ihrer herstellung
US4321268A (en) * 1979-02-08 1982-03-23 Merz & Co. Certain substituted phenyl esters of nicotinic acid, compositions and methods of using same
GB2193359B (en) * 1986-07-31 1990-07-11 Multitone Electronics Plc Area communications systems
US4797656A (en) * 1987-01-28 1989-01-10 Keppler Charles N Appliance paging system
US5012749A (en) * 1988-12-27 1991-05-07 The Allen Group Inc. Radio controlled material handling apparatus
US4962377A (en) * 1989-02-09 1990-10-09 Motorola, Inc. Paging by text matching

Also Published As

Publication number Publication date
YU74384A (en) 1986-10-31
AU2760484A (en) 1984-11-08
JPS6127389B2 (fr) 1986-06-25
HUT34162A (en) 1985-02-28
IE841074L (en) 1984-11-02
CS325284A2 (en) 1985-06-13
SE8402297D0 (sv) 1984-04-26
FI80444B (fi) 1990-02-28
GB2139621B (en) 1986-10-29
FR2545486A1 (fr) 1984-11-09
IE57393B1 (en) 1992-08-26
GB8411081D0 (en) 1984-06-06
GB2139621A (en) 1984-11-14
DK216484D0 (da) 1984-05-01
KR840009091A (ko) 1984-12-24
CH660005A5 (de) 1987-03-13
CS241082B2 (en) 1986-03-13
DE3315877A1 (de) 1984-11-08
IT8420763A0 (it) 1984-05-02
ZA843278B (en) 1985-12-24
SE8402297L (sv) 1984-11-03
DK159105C (da) 1991-02-11
DK216484A (da) 1984-11-03
FR2545486B1 (fr) 1986-12-26
AU564780B2 (en) 1987-08-27
FI80444C (fi) 1990-06-11
JPS59206357A (ja) 1984-11-22
ES532079A0 (es) 1985-03-16
US4758581A (en) 1988-07-19
FI841736A0 (fi) 1984-05-02
NL8401357A (nl) 1984-12-03
HU191681B (en) 1987-03-30
YU45900B (sh) 1992-09-07
GR79862B (fr) 1984-10-31
ES8503660A1 (es) 1985-03-16
DE3315877C2 (fr) 1989-11-30
IT1206144B (it) 1989-04-14
KR860001907B1 (ko) 1986-10-24
CA1247092A (fr) 1988-12-20
LU85344A1 (fr) 1986-01-29
BE899558A (fr) 1984-11-05
FI841736A (fi) 1984-11-03
IL71734A0 (en) 1984-09-30
DK159105B (da) 1990-09-03
SE454986B (sv) 1988-06-13

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