IL70880A - N-methyl-s-methyl-n'(2-(2-dimethylaminomethylthiazol-4-ylmethylthio)ethyl)-isothiourea,its preparation and use in the preparation of nizatidine - Google Patents
N-methyl-s-methyl-n'(2-(2-dimethylaminomethylthiazol-4-ylmethylthio)ethyl)-isothiourea,its preparation and use in the preparation of nizatidineInfo
- Publication number
- IL70880A IL70880A IL70880A IL7088084A IL70880A IL 70880 A IL70880 A IL 70880A IL 70880 A IL70880 A IL 70880A IL 7088084 A IL7088084 A IL 7088084A IL 70880 A IL70880 A IL 70880A
- Authority
- IL
- Israel
- Prior art keywords
- methyl
- preparation
- ylmethylthio
- isothiourea
- nizatidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46429683A | 1983-02-07 | 1983-02-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL70880A0 IL70880A0 (en) | 1984-05-31 |
IL70880A true IL70880A (en) | 1987-01-30 |
Family
ID=23843341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL70880A IL70880A (en) | 1983-02-07 | 1984-02-06 | N-methyl-s-methyl-n'(2-(2-dimethylaminomethylthiazol-4-ylmethylthio)ethyl)-isothiourea,its preparation and use in the preparation of nizatidine |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP0116452B1 (es) |
JP (1) | JPS59152378A (es) |
KR (1) | KR860000767B1 (es) |
AT (1) | ATE84530T1 (es) |
AU (1) | AU559639B2 (es) |
BG (1) | BG45216A3 (es) |
CA (1) | CA1221369A (es) |
CS (1) | CS240994B2 (es) |
DD (1) | DD216459A5 (es) |
DE (1) | DE3486032T2 (es) |
DK (2) | DK164501C (es) |
EG (1) | EG17702A (es) |
ES (1) | ES529492A0 (es) |
FI (1) | FI840474A (es) |
GB (1) | GB2134521B (es) |
GR (1) | GR81755B (es) |
HU (2) | HU190527B (es) |
IE (1) | IE56763B1 (es) |
IL (1) | IL70880A (es) |
NZ (1) | NZ207046A (es) |
PH (1) | PH19941A (es) |
PL (1) | PL138793B1 (es) |
PT (1) | PT78063A (es) |
RO (1) | RO87706A (es) |
SU (1) | SU1303028A3 (es) |
UA (1) | UA6020A1 (es) |
ZA (1) | ZA84869B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL80961A0 (en) * | 1985-12-18 | 1987-03-31 | Lilly Co Eli | Synthesis of nizatidine |
ES2038922B1 (es) * | 1991-12-30 | 1994-04-16 | Fermentaciones Y Sintesis Espa | Procedimiento para la obtencion de nizatidina. |
US5470865A (en) * | 1994-08-30 | 1995-11-28 | Eli Lilly And Company | Pharmaceutical composition |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4200578A (en) * | 1978-12-18 | 1980-04-29 | Bristol-Myers Company | Thiazole derivatives |
US4375547A (en) * | 1980-10-02 | 1983-03-01 | Eli Lilly And Company | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
-
1984
- 1984-02-06 BG BG8464154A patent/BG45216A3/xx unknown
- 1984-02-06 GR GR73715A patent/GR81755B/el unknown
- 1984-02-06 DD DD84259880A patent/DD216459A5/de unknown
- 1984-02-06 EP EP84300720A patent/EP0116452B1/en not_active Expired - Lifetime
- 1984-02-06 FI FI840474A patent/FI840474A/fi not_active Application Discontinuation
- 1984-02-06 PT PT78063A patent/PT78063A/pt not_active IP Right Cessation
- 1984-02-06 IE IE274/84A patent/IE56763B1/en not_active IP Right Cessation
- 1984-02-06 GB GB08403109A patent/GB2134521B/en not_active Expired
- 1984-02-06 CS CS84812A patent/CS240994B2/cs unknown
- 1984-02-06 ZA ZA84869A patent/ZA84869B/xx unknown
- 1984-02-06 SU SU843700902A patent/SU1303028A3/ru active
- 1984-02-06 AU AU24215/84A patent/AU559639B2/en not_active Ceased
- 1984-02-06 IL IL70880A patent/IL70880A/xx not_active IP Right Cessation
- 1984-02-06 CA CA000446798A patent/CA1221369A/en not_active Expired
- 1984-02-06 AT AT84300720T patent/ATE84530T1/de not_active IP Right Cessation
- 1984-02-06 HU HU84477A patent/HU190527B/hu not_active IP Right Cessation
- 1984-02-06 DK DK051984A patent/DK164501C/da not_active IP Right Cessation
- 1984-02-06 RO RO84113523A patent/RO87706A/ro unknown
- 1984-02-06 UA UA3700902A patent/UA6020A1/uk unknown
- 1984-02-06 DE DE8484300720T patent/DE3486032T2/de not_active Expired - Lifetime
- 1984-02-06 HU HU86873A patent/HU194198B/hu unknown
- 1984-02-06 PH PH30202A patent/PH19941A/en unknown
- 1984-02-06 ES ES529492A patent/ES529492A0/es active Granted
- 1984-02-07 NZ NZ207046A patent/NZ207046A/en unknown
- 1984-02-07 JP JP59021529A patent/JPS59152378A/ja active Granted
- 1984-02-07 PL PL1984246097A patent/PL138793B1/pl unknown
- 1984-02-07 KR KR1019840000567A patent/KR860000767B1/ko not_active IP Right Cessation
- 1984-02-07 EG EG92/84A patent/EG17702A/xx active
-
1992
- 1992-02-19 DK DK021292A patent/DK164906C/da not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
EXP | Patent expired |