IL69993A - Derivatives of 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1 j-k)(1)-benzazepin-2(1h)-one,their salts,their preparation and pharmaceutical compositions containing them - Google Patents

Derivatives of 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1 j-k)(1)-benzazepin-2(1h)-one,their salts,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL69993A
IL69993A IL69993A IL6999383A IL69993A IL 69993 A IL69993 A IL 69993A IL 69993 A IL69993 A IL 69993A IL 6999383 A IL6999383 A IL 6999383A IL 69993 A IL69993 A IL 69993A
Authority
IL
Israel
Prior art keywords
amino
carbon atoms
benzazepin
hydroxy
derivatives
Prior art date
Application number
IL69993A
Other languages
English (en)
Other versions
IL69993A0 (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IL69993A0 publication Critical patent/IL69993A0/xx
Publication of IL69993A publication Critical patent/IL69993A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL69993A 1982-10-12 1983-10-18 Derivatives of 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1 j-k)(1)-benzazepin-2(1h)-one,their salts,their preparation and pharmaceutical compositions containing them IL69993A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8217054A FR2534257A1 (fr) 1982-10-12 1982-10-12 Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire

Publications (2)

Publication Number Publication Date
IL69993A0 IL69993A0 (en) 1984-01-31
IL69993A true IL69993A (en) 1987-10-30

Family

ID=9278183

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69993A IL69993A (en) 1982-10-12 1983-10-18 Derivatives of 6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1 j-k)(1)-benzazepin-2(1h)-one,their salts,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US4585770A (sv)
EP (1) EP0107569B1 (sv)
JP (1) JPS59130289A (sv)
KR (1) KR900006753B1 (sv)
AT (1) ATE25981T1 (sv)
AU (1) AU559422B2 (sv)
CA (2) CA1216847A (sv)
DD (1) DD215784A5 (sv)
DE (1) DE3370332D1 (sv)
DK (1) DK163734C (sv)
ES (1) ES526390A0 (sv)
FI (1) FI76340C (sv)
FR (1) FR2534257A1 (sv)
GR (1) GR78731B (sv)
HU (1) HU188499B (sv)
IE (1) IE59441B1 (sv)
IL (1) IL69993A (sv)
MX (1) MX8495A (sv)
NZ (1) NZ205918A (sv)
PH (1) PH20031A (sv)
PT (1) PT77469B (sv)
SU (2) SU1287753A3 (sv)
ZA (1) ZA837480B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU616390B2 (en) * 1986-12-11 1991-10-31 Hoechst Roussel Vet S.A. Zootechnical compositions containing a beta-adrenergic
FR2608046B1 (fr) * 1986-12-11 1989-03-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5, 1-j-k/ /1/benzazepin-2-(1h)-one
IE60964B1 (en) * 1986-12-11 1994-09-07 Roussel Uclaf Zootechnical compositions containing a beta-adrenergic
FR2608047B1 (fr) * 1986-12-11 1990-08-31 Roussel Uclaf Compositions zootechniques renfermant un derive de la 6-amino 7-hydroxy 4,5,6,7-tetrahydroimidazo /4,5,1-j-k/ /1/ benzazepin-2-(1h)-one
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
FR2735474B1 (fr) * 1995-06-13 1997-08-08 Roussel Uclaf Chlorhydrate de zilpaterol sous une forme cristallisee particuliere, son procede de preparation et les produits intermediaires mis en oeuvre
US7207289B2 (en) * 2004-05-20 2007-04-24 Intervet International B.V. Method of feeding the cattle with feed additives that increases beef production and reduces liver abscess
KR20090071632A (ko) * 2006-10-13 2009-07-01 화이자 리미티드 가축 동물에 대한 동화 제제로서 유용한 헤테로사이클릭 화합물
WO2008050207A1 (en) * 2006-10-25 2008-05-02 Pfizer Limited Heterocyclic compounds useful as anabolic agents for livestock animals
KR101150634B1 (ko) * 2007-02-01 2012-07-04 인터벳 인터내셔널 비.브이. 6-아미노-7-히드록시-4,5,6,7-테트라히드로-이미다조［4,5,1-ｊｋ］［1］-벤즈아제핀-2［1ｈ］-온 및 질파테롤의 에난시오선택적 합성
RU2442786C2 (ru) * 2007-03-31 2012-02-20 Интервет Интернэшнл Б.В. Способы получения зилпатерола и его солей
HK1136565A1 (en) * 2007-03-31 2010-07-02 Intervet Int Bv Processes for making zilpaterol and salts thereof
HUE028171T2 (en) * 2007-03-31 2016-12-28 Intervet Int Bv Methods for preparing zilpaterol and its salts
KR101240147B1 (ko) * 2007-03-31 2013-03-08 인터벳 인터내셔널 비.브이. 질파테롤 및 이의 염의 제조 방법
EP1995248A1 (en) * 2007-05-23 2008-11-26 Evonik Degussa GmbH Process for the production of amino alcohols by asymmetric hydrogenation
CN101918001B (zh) 2007-12-06 2016-11-16 英特威国际有限公司 使用醋酸美仑孕酮和齐帕特罗或其盐的联合治疗
TW201033217A (en) * 2008-12-17 2010-09-16 Intervet Int Bv Process for making a crystalline zilpaterol salt
CN104284598A (zh) 2012-05-18 2015-01-14 英特维特国际股份有限公司 增强肉用仔鸡性能的方法
AU2013363731B2 (en) 2012-12-18 2018-04-19 Intervet International B.V. An improved process for making zilpaterol
US20160022694A1 (en) 2013-03-15 2016-01-28 Intervet Inc. A Method of Improving the Efficiency of Beef Production from Bovine Animals
CN104418808A (zh) * 2013-09-11 2015-03-18 中美华世通生物医药科技（武汉）有限公司 一种适于工业化生产的中间体Buzolic acid的制备方法
CN103554113B (zh) * 2013-09-25 2016-04-27 湖北美天生物科技有限公司 一种盐酸齐帕特罗的合成方法
MX2018000862A (es) 2015-07-21 2018-05-15 Intervet Int Bv Una novedosa formulacion de premezcla animal de zilpaterol.
EP3488705A1 (en) 2017-11-23 2019-05-29 Saviela AG Solubilized growth promoting product to be applied orally to animals and method for the respective feed preparation
CN108752352B (zh) * 2018-04-18 2019-11-26 江苏凌云药业股份有限公司 一种盐酸齐帕特罗的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2320439A (en) * 1943-06-01 Bottle carrier
US3200123A (en) * 1962-01-26 1965-08-10 Richardson Merreil Inc Imidazoquinolines
DE3161072D1 (en) * 1980-02-26 1983-11-10 Roussel Uclaf Cycloheptindolol derivatives and their acid-addition salts, their preparation, their use as medicines and composition containing them

Also Published As

Publication number Publication date
DK163734C (da) 1992-08-31
DK466483D0 (da) 1983-10-11
IL69993A0 (en) 1984-01-31
FI833697A (fi) 1984-04-13
FR2534257B1 (sv) 1984-12-28
SU1384201A3 (ru) 1988-03-23
JPH0454671B2 (sv) 1992-08-31
PT77469A (fr) 1983-11-01
DK466483A (da) 1984-04-13
US4585770A (en) 1986-04-29
IE59441B1 (en) 1994-02-23
NZ205918A (en) 1985-12-13
KR840006484A (ko) 1984-11-30
SU1287753A3 (ru) 1987-01-30
ES8405802A1 (es) 1984-06-16
PH20031A (en) 1986-09-04
IE832387L (en) 1984-04-12
FR2534257A1 (fr) 1984-04-13
MX8495A (es) 1993-09-01
KR900006753B1 (ko) 1990-09-20
ES526390A0 (es) 1984-06-16
DE3370332D1 (en) 1987-04-23
CA1216847A (fr) 1987-01-20
ATE25981T1 (de) 1987-04-15
HU188499B (en) 1986-04-28
GR78731B (sv) 1984-10-02
PT77469B (fr) 1986-05-07
ZA837480B (en) 1984-11-28
DD215784A5 (de) 1984-11-21
FI833697A0 (fi) 1983-10-11
FI76340C (sv) 1988-10-10
EP0107569A1 (fr) 1984-05-02
AU2005383A (en) 1984-04-19
DK163734B (da) 1992-03-30
AU559422B2 (en) 1987-03-12
FI76340B (fi) 1988-06-30
EP0107569B1 (fr) 1987-03-18
CA1222246A (fr) 1987-05-26
JPS59130289A (ja) 1984-07-26

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