IL68913A - 3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL68913A
IL68913A IL68913A IL6891383A IL68913A IL 68913 A IL68913 A IL 68913A IL 68913 A IL68913 A IL 68913A IL 6891383 A IL6891383 A IL 6891383A IL 68913 A IL68913 A IL 68913A
Authority
IL
Israel
Prior art keywords
alkan
aminoalkyl
indole
preparation
pharmaceutical compositions
Prior art date
Application number
IL68913A
Other languages
English (en)
Other versions
IL68913A0 (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10530876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL68913(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL68913A0 publication Critical patent/IL68913A0/xx
Publication of IL68913A publication Critical patent/IL68913A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IL68913A 1982-06-07 1983-06-07 3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them IL68913A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8216526 1982-06-07

Publications (2)

Publication Number Publication Date
IL68913A0 IL68913A0 (en) 1983-10-31
IL68913A true IL68913A (en) 1987-08-31

Family

ID=10530876

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68913A IL68913A (en) 1982-06-07 1983-06-07 3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them

Country Status (33)

Country Link
US (1) US4816470A (pt)
JP (1) JPS5942366A (pt)
KR (1) KR900006681B1 (pt)
AT (1) AT381933B (pt)
AU (1) AU566149B2 (pt)
BE (1) BE896986A (pt)
CA (1) CA1199643A (pt)
CH (1) CH657359A5 (pt)
CY (1) CY1458A (pt)
CZ (1) CZ280529B6 (pt)
DE (2) DE19375045I2 (pt)
DK (1) DK260183D0 (pt)
DO (1) DOP1989476000A (pt)
ES (3) ES8407473A1 (pt)
FI (1) FI79530C (pt)
FR (1) FR2530625B1 (pt)
GB (1) GB2124210B (pt)
GR (1) GR79215B (pt)
HK (1) HK14789A (pt)
IE (1) IE55358B1 (pt)
IL (1) IL68913A (pt)
IT (1) IT1170387B (pt)
KE (1) KE3833A (pt)
LU (1) LU84852A1 (pt)
MX (1) MX9202623A (pt)
MY (1) MY8700179A (pt)
NL (1) NL193694C (pt)
NZ (1) NZ204482A (pt)
PH (1) PH19908A (pt)
PT (1) PT76830B (pt)
SE (1) SE452459B (pt)
SK (1) SK404091A3 (pt)
ZA (1) ZA834110B (pt)

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GB9013845D0 (en) * 1990-06-21 1990-08-15 Glaxo Group Ltd Process
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US5618816A (en) * 1995-03-02 1997-04-08 Bristol-Myers Squibb Company Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridnyl and pyrimidinylpiperazines
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US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
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ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
NZ197998A (en) * 1980-08-12 1985-08-16 Glaxo Group Ltd 5-amino(methyl)-1h-indol-3-ylalkaneamines
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
NZ197996A (en) * 1980-08-12 1985-08-16 Glaxo Group Ltd 1-(3-(omega-aminoalkyl)-1h-indol-5-yl)alkanamides

Also Published As

Publication number Publication date
GB2124210B (en) 1985-11-13
US4816470A (en) 1989-03-28
ES8609247A1 (es) 1986-07-16
KR900006681B1 (ko) 1990-09-17
GR79215B (pt) 1984-10-22
KE3833A (en) 1988-11-18
IT8348422A0 (it) 1983-06-03
DE19375045I2 (de) 2002-09-05
ES523039A0 (es) 1984-10-01
IE831335L (en) 1983-12-07
CY1458A (en) 1989-07-21
JPH0329069B2 (pt) 1991-04-23
ES8407473A1 (es) 1984-10-01
SE8303208L (sv) 1983-12-08
ES544281A0 (es) 1986-07-16
KR840005095A (ko) 1984-11-03
PT76830B (en) 1986-04-21
DE3320521A1 (de) 1983-12-08
FI79530B (fi) 1989-09-29
IL68913A0 (en) 1983-10-31
FR2530625B1 (fr) 1986-04-18
SK277877B6 (en) 1995-06-07
CZ404091A3 (en) 1993-04-14
JPS5942366A (ja) 1984-03-08
BE896986A (fr) 1983-12-07
CA1199643A (en) 1986-01-21
GB8315564D0 (en) 1983-07-13
IT1170387B (it) 1987-06-03
NZ204482A (en) 1986-09-10
MX9202623A (es) 1992-06-30
ATA208483A (de) 1986-05-15
MY8700179A (en) 1987-12-31
CH657359A5 (fr) 1986-08-29
GB2124210A (en) 1984-02-15
AU566149B2 (en) 1987-10-08
PH19908A (en) 1986-08-13
FI79530C (fi) 1990-01-10
PT76830A (en) 1983-07-01
NL8302031A (nl) 1984-01-02
FI832035L (fi) 1983-12-08
FR2530625A1 (fr) 1984-01-27
DK260183D0 (da) 1983-06-06
NL193694C (nl) 2000-07-04
SE452459B (sv) 1987-11-30
HK14789A (en) 1989-02-24
CZ280529B6 (cs) 1996-02-14
LU84852A1 (fr) 1985-03-29
DE3320521C2 (pt) 1992-06-25
AT381933B (de) 1986-12-10
IE55358B1 (en) 1990-08-29
ES529802A0 (es) 1985-11-16
FI832035A0 (fi) 1983-06-07
NL193694B (nl) 2000-03-01
SE8303208D0 (sv) 1983-06-07
ES8601880A1 (es) 1985-11-16
DOP1989476000A (es) 1996-02-03
SK404091A3 (en) 1995-06-07
ZA834110B (en) 1985-01-30
AU1544183A (en) 1983-12-15

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