IL67291A0 - (4-oxo-4h-(1)-benzopyran-8-yl)alkanoic acids and salts and derivatives thereof,their manufacture and pharmaceutical compositions containing them - Google Patents

(4-oxo-4h-(1)-benzopyran-8-yl)alkanoic acids and salts and derivatives thereof,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL67291A0
IL67291A0 IL67291A IL6729182A IL67291A0 IL 67291 A0 IL67291 A0 IL 67291A0 IL 67291 A IL67291 A IL 67291A IL 6729182 A IL6729182 A IL 6729182A IL 67291 A0 IL67291 A0 IL 67291A0
Authority
IL
Israel
Prior art keywords
derivatives
benzopyran
oxo
salts
manufacture
Prior art date
Application number
IL67291A
Other languages
English (en)
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha filed Critical Lipha
Publication of IL67291A0 publication Critical patent/IL67291A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL67291A 1981-11-25 1982-11-17 (4-oxo-4h-(1)-benzopyran-8-yl)alkanoic acids and salts and derivatives thereof,their manufacture and pharmaceutical compositions containing them IL67291A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8122020A FR2516922A1 (fr) 1981-11-25 1981-11-25 Acides (oxo-4-4h-(1)-benzopyran-8-yl) alcanoiques, sels et derives, preparation et medicament les contenant

Publications (1)

Publication Number Publication Date
IL67291A0 true IL67291A0 (en) 1983-03-31

Family

ID=9264332

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67291A IL67291A0 (en) 1981-11-25 1982-11-17 (4-oxo-4h-(1)-benzopyran-8-yl)alkanoic acids and salts and derivatives thereof,their manufacture and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (2) US4602034A (enEXAMPLES)
EP (1) EP0080934B1 (enEXAMPLES)
JP (1) JPS5896082A (enEXAMPLES)
AT (1) ATE31927T1 (enEXAMPLES)
AU (1) AU563190B2 (enEXAMPLES)
CA (1) CA1213595A (enEXAMPLES)
CS (1) CS248035B2 (enEXAMPLES)
DD (1) DD204919A5 (enEXAMPLES)
DE (1) DE3277970D1 (enEXAMPLES)
DK (1) DK164163C (enEXAMPLES)
ES (1) ES8308323A1 (enEXAMPLES)
FR (1) FR2516922A1 (enEXAMPLES)
HU (1) HU192112B (enEXAMPLES)
IE (1) IE54130B1 (enEXAMPLES)
IL (1) IL67291A0 (enEXAMPLES)
IN (1) IN158843B (enEXAMPLES)
MA (1) MA19650A1 (enEXAMPLES)
MX (1) MX173498B (enEXAMPLES)
NO (1) NO159169C (enEXAMPLES)
NZ (1) NZ202596A (enEXAMPLES)
OA (1) OA07257A (enEXAMPLES)
SU (1) SU1250171A3 (enEXAMPLES)
YU (2) YU43726B (enEXAMPLES)
ZA (1) ZA828436B (enEXAMPLES)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2536397A2 (en) * 1981-11-25 1984-05-25 Lipha [4-oxo-4H-1-Benzopyran-8-yl]alkanoic acids, their salts and derivatives, their preparation and medicinal products containing them
DE3311004A1 (de) * 1983-03-25 1984-09-27 Bayer Ag, 5090 Leverkusen Chromon- und thiochromon-8-aldehyde, sowie ein verfahren zu ihrer herstellung
JPS62215581A (ja) * 1986-03-18 1987-09-22 Koichi Shiyudo フラボンカルボン酸誘導体
IL85554A0 (en) * 1987-03-02 1988-08-31 Takeda Chemical Industries Ltd Chromone derivatives
IL89840A (en) * 1988-04-06 1996-10-31 Lipha Substituted flavonoid compounds and salts thereof their preparation and pharmaceutical composition containing them
USH1427H (en) * 1988-04-06 1995-04-04 Briet; Phillipe Substituted flavonoid compounds, their salts, their manufacture and their use in combination with interleukin-2
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
US5126129A (en) * 1988-05-23 1992-06-30 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Cancer therapy using interleukin-2 and flavone compounds
ES2062507T3 (es) * 1989-01-19 1994-12-16 Upjohn Co Acido flavonacetico fluorado.
US5238954A (en) * 1989-01-19 1993-08-24 The Upjohn Company Fluorinated flavone acetic acid
NZ246593A (en) * 1992-02-05 1997-07-27 Boehringer Ingelheim Int Amidine derivatives; their preparation and medicaments containing them
US5703130A (en) * 1995-06-07 1997-12-30 Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences Chalcone retinoids and methods of use of same
US5716982A (en) * 1995-06-07 1998-02-10 Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences Retinoids and methods of use of same
US5968940A (en) * 1995-06-08 1999-10-19 Institute Of Materia Medica Retinoids and methods of use of same
ATE324888T1 (de) * 1999-06-14 2006-06-15 Cancer Rec Tech Ltd Krebstherapie
AU2001232917A1 (en) 2000-01-24 2001-07-31 Jozef S. Mruk Use of flavone 8-acetic acid in vascular and cardiovascular interventions and acute coronary syndromes
EP1311262A4 (en) * 2000-07-28 2005-06-01 Cancer Rec Tech Ltd COMBINED TREATMENT AGAINST CANCER
GB0121285D0 (en) * 2001-09-03 2001-10-24 Cancer Res Ventures Ltd Anti-cancer combinations
GB2386836B (en) * 2002-03-22 2006-07-26 Cancer Res Ventures Ltd Anti-cancer combinations
GB2394658A (en) * 2002-11-01 2004-05-05 Cancer Rec Tech Ltd Oral anti-cancer composition
GB0321999D0 (en) * 2003-09-19 2003-10-22 Cancer Rec Tech Ltd Anti-cancer combinations
KR20080047402A (ko) * 2005-08-26 2008-05-28 안티소마 피엘씨 Ｄｍｘａａ를 포함하는 암 치료용 조합물
EP2470174A1 (en) 2009-08-27 2012-07-04 Merck Patent GmbH Use of faa and its derivatives in cosmetics and dermatology
EA036876B1 (ru) * 2009-11-05 2020-12-30 Ризен Фармасьютикалз С.А. Ингибиторы pi3k киназы
CN103304531A (zh) * 2013-06-25 2013-09-18 南方医科大学 一种3-芳基黄酮乙酸
JP2019507796A (ja) * 2016-03-11 2019-03-22 エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド イカリイン及びイカリチン誘導体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921070A (en) * 1957-11-05 1960-01-12 Recordati Lab Farmacologico S Basic esters of 3-methylflavone-8-carboxylic acid
US3350411A (en) * 1963-10-10 1967-10-31 Pharma Seceph S A Soc D Expl C Process for preparing 3-methylflavone-8-carboxylic acid
BE757821A (fr) * 1970-08-01 1971-04-01 Recordati Chem Pharm Procede de preparation de l'acide 3-propionyl-salicylique et dederives de cet acide
GB1479518A (en) * 1973-12-27 1977-07-13 Erba Carlo Spa 5,6-benzo-ypsilon-pyrone derivatives
US4148900A (en) * 1973-12-27 1979-04-10 Carlo Erba S.P.A. 5:6-Benzo-γ-pyrone derivatives and process for their preparation
FR2281112A1 (fr) * 1974-08-05 1976-03-05 Lipha Nouveau medicament choleretique et anti-inflammatoire
GB1469823A (en) * 1974-08-13 1977-04-06 Farma Lepori Flavone derivatives
DE2549745A1 (de) * 1974-11-20 1976-05-26 Lipha Durch einen chromonylrest substituierte propionsaeuren sowie deren derivate und verwendungen

Also Published As

Publication number Publication date
JPS5896082A (ja) 1983-06-07
HU192112B (en) 1987-05-28
FR2516922B1 (enEXAMPLES) 1984-02-10
EP0080934A1 (fr) 1983-06-08
ATE31927T1 (de) 1988-01-15
AU563190B2 (en) 1987-07-02
YU163084A (en) 1985-03-20
DK164163C (da) 1992-10-19
DD204919A5 (de) 1983-12-14
ZA828436B (en) 1983-09-28
US4783533A (en) 1988-11-08
NO159169C (no) 1988-12-07
NO159169B (no) 1988-08-29
IN158843B (enEXAMPLES) 1987-01-31
YU43675B (en) 1989-10-31
SU1250171A3 (ru) 1986-08-07
NZ202596A (en) 1986-02-21
NO823940L (no) 1983-05-26
IE54130B1 (en) 1989-06-21
FR2516922A1 (fr) 1983-05-27
DE3277970D1 (en) 1988-02-18
MX173498B (es) 1994-03-10
EP0080934B1 (fr) 1988-01-13
JPH0214352B2 (enEXAMPLES) 1990-04-06
OA07257A (fr) 1984-04-30
US4602034A (en) 1986-07-22
YU264982A (en) 1984-12-31
YU43726B (en) 1989-10-31
ES517637A0 (es) 1983-08-16
ES8308323A1 (es) 1983-08-16
AU9073082A (en) 1983-06-02
IE822752L (en) 1983-05-25
CS248035B2 (en) 1987-01-15
CA1213595A (fr) 1986-11-04
DK164163B (da) 1992-05-18
MA19650A1 (fr) 1983-07-01
DK523082A (da) 1983-05-26

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Legal Events

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