IL66606A - 4-oxo-3h-imizado(5,1-d)1,2,3,5-tetrazine-8-carboxamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

4-oxo-3h-imizado(5,1-d)1,2,3,5-tetrazine-8-carboxamide derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL66606A
IL66606A IL66606A IL6660682A IL66606A IL 66606 A IL66606 A IL 66606A IL 66606 A IL66606 A IL 66606A IL 6660682 A IL6660682 A IL 6660682A IL 66606 A IL66606 A IL 66606A
Authority
IL
Israel
Prior art keywords
imizado
tetrazine
oxo
preparation
pharmaceutical compositions
Prior art date
Application number
IL66606A
Other languages
English (en)
Other versions
IL66606A0 (en
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of IL66606A0 publication Critical patent/IL66606A0/xx
Publication of IL66606A publication Critical patent/IL66606A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL66606A 1981-08-24 1982-08-12 4-oxo-3h-imizado(5,1-d)1,2,3,5-tetrazine-8-carboxamide derivatives,their preparation and pharmaceutical compositions containing them IL66606A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
IL66606A0 IL66606A0 (en) 1982-12-31
IL66606A true IL66606A (en) 1987-07-31

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66606A IL66606A (en) 1981-08-24 1982-08-12 4-oxo-3h-imizado(5,1-d)1,2,3,5-tetrazine-8-carboxamide derivatives,their preparation and pharmaceutical compositions containing them

Country Status (29)

Country Link
JP (1) JPS5843975A (en:Method)
KR (1) KR890000094B1 (en:Method)
AT (1) AT380256B (en:Method)
AU (1) AU571430B2 (en:Method)
BE (1) BE894175A (en:Method)
CA (1) CA1197247A (en:Method)
CH (1) CH655114A5 (en:Method)
DE (2) DE3231255A1 (en:Method)
DK (1) DK161147C (en:Method)
ES (1) ES8400438A1 (en:Method)
FI (1) FI73434C (en:Method)
FR (1) FR2511679A1 (en:Method)
GB (1) GB2104522B (en:Method)
GE (1) GEP19960641B (en:Method)
GR (1) GR76863B (en:Method)
HU (1) HU186107B (en:Method)
IE (1) IE53408B1 (en:Method)
IL (1) IL66606A (en:Method)
IT (1) IT1152505B (en:Method)
LT (1) LT2436B (en:Method)
LU (1) LU84347A1 (en:Method)
LV (2) LV5511A3 (en:Method)
NL (2) NL192739C (en:Method)
NZ (1) NZ201668A (en:Method)
OA (1) OA07174A (en:Method)
SE (1) SE448543B (en:Method)
SU (1) SU1447284A3 (en:Method)
UA (1) UA5971A1 (en:Method)
ZA (1) ZA826120B (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
GR78688B (en:Method) * 1982-08-17 1984-09-27 May & Baker Ltd
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
JPH11511479A (ja) * 1995-09-25 1999-10-05 サノフィ ファーマシューティカルズ，インコーポレイティド １，２，４−ベンゾトリアジンオキシド製剤
BRPI0417117A (pt) * 2003-12-30 2007-03-06 Chemagis Ltd temozolomida cristalizada, processo de preparação de temozolomida cristalizada, composição farmacêutica, método de produção de medicamento contendo temozolomida e método de tratamento de uma condição médica para a qual a termozolomida é benéfica
CA2594477C (en) 2005-01-21 2016-07-12 Astex Therapeutics Limited Pharmaceutical compounds
PE20080695A1 (es) 2006-04-27 2008-06-28 Banyu Pharma Co Ltd Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US8329711B2 (en) 2007-10-23 2012-12-11 Msd K.K. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
US8716471B2 (en) * 2008-11-24 2014-05-06 Reliance Life Sciences Pvt. Ltd. Process for the preparation of tetrazine derivatives
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
CA2763766A1 (en) 2009-06-23 2010-12-29 Pharminox Limited 3-substituted-8-substituted-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
ES3057783T3 (en) 2016-03-15 2026-03-04 Oryzon Genomics Sa Combinations of lsd1 inhibitors for use in the treatment of neoplastic diseases
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Also Published As

Publication number Publication date
KR840001175A (ko) 1984-03-28
SE448543B (sv) 1987-03-02
SU1447284A3 (ru) 1988-12-23
BE894175A (fr) 1983-02-23
ES515176A0 (es) 1983-11-01
FI822921A0 (fi) 1982-08-23
DE3231255A1 (de) 1983-03-03
FR2511679B1 (en:Method) 1985-02-01
GB2104522B (en) 1985-06-12
AU8749382A (en) 1983-03-03
NZ201668A (en) 1985-08-16
FI73434B (fi) 1987-06-30
FI73434C (fi) 1987-10-09
ATA319182A (de) 1985-09-15
LV5621A3 (lv) 1994-05-10
UA5971A1 (uk) 1994-12-29
LU84347A1 (fr) 1983-06-07
NL8203286A (nl) 1983-03-16
KR890000094B1 (ko) 1989-03-07
IT8222938A1 (it) 1984-02-23
AT380256B (de) 1986-05-12
IE53408B1 (en) 1988-11-09
CA1197247A (fr) 1985-11-26
GB2104522A (en) 1983-03-09
JPS5843975A (ja) 1983-03-14
DK161147C (da) 1991-11-18
IL66606A0 (en) 1982-12-31
ES8400438A1 (es) 1983-11-01
NL192739C (nl) 1998-01-06
CH655114A5 (fr) 1986-03-27
NL990010I1 (nl) 1999-07-01
SE8204817L (sv) 1983-02-25
AU571430B2 (en) 1988-04-21
DE3231255C2 (en:Method) 1992-02-27
DE19975037I2 (de) 2001-06-13
FR2511679A1 (fr) 1983-02-25
NL990010I2 (nl) 1999-09-01
NL192739B (nl) 1997-09-01
GR76863B (en:Method) 1984-09-04
DK161147B (da) 1991-06-03
HU186107B (en) 1985-06-28
ZA826120B (en) 1983-07-27
JPH045029B2 (en:Method) 1992-01-30
OA07174A (fr) 1984-04-30
IE822026L (en) 1983-02-24
FI822921L (fi) 1983-02-25
IT1152505B (it) 1987-01-07
DK377882A (da) 1983-02-25
SE8204817D0 (sv) 1982-08-23
LT2436B (lt) 1994-02-15
LV5511A3 (lv) 1994-03-10
IT8222938A0 (it) 1982-08-23
GEP19960641B (en) 1996-11-15

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