IL35916A - 1,2,3,4-tetrahydro-4-phenyl iso-quinoline derivatives and their preparation - Google Patents

1,2,3,4-tetrahydro-4-phenyl iso-quinoline derivatives and their preparation

Info

Publication number
IL35916A
IL35916A IL35916A IL3591670A IL35916A IL 35916 A IL35916 A IL 35916A IL 35916 A IL35916 A IL 35916A IL 3591670 A IL3591670 A IL 3591670A IL 35916 A IL35916 A IL 35916A
Authority
IL
Israel
Prior art keywords
tetrahydro
preparation
quinoline derivatives
phenyl iso
iso
Prior art date
Application number
IL35916A
Other languages
English (en)
Other versions
IL35916A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL35916A0 publication Critical patent/IL35916A0/xx
Publication of IL35916A publication Critical patent/IL35916A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL35916A 1970-01-06 1970-12-28 1,2,3,4-tetrahydro-4-phenyl iso-quinoline derivatives and their preparation IL35916A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (2)

Publication Number Publication Date
IL35916A0 IL35916A0 (en) 1971-02-25
IL35916A true IL35916A (en) 1973-11-28

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
IL35916A IL35916A (en) 1970-01-06 1970-12-28 1,2,3,4-tetrahydro-4-phenyl iso-quinoline derivatives and their preparation

Country Status (19)

Country Link
JP (1) JPS5515476B1 (instruction)
AT (1) AT303041B (instruction)
BE (1) BE761219A (instruction)
CA (1) CA999866A (instruction)
CH (2) CH527194A (instruction)
DE (1) DE2062001C2 (instruction)
DK (1) DK125021B (instruction)
ES (1) ES387016A1 (instruction)
FI (1) FI49503C (instruction)
FR (1) FR2081412B1 (instruction)
GB (1) GB1335261A (instruction)
IE (1) IE34859B1 (instruction)
IL (1) IL35916A (instruction)
NL (1) NL171444C (instruction)
NO (1) NO135315C (instruction)
PH (1) PH9682A (instruction)
SE (3) SE386672B (instruction)
YU (1) YU33660B (instruction)
ZA (1) ZA708590B (instruction)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
RU2309953C2 (ru) 1999-11-03 2007-11-10 Эймр Текнолоджи, Инк. Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
AU784280B2 (en) * 1999-11-03 2006-03-02 Albany Molecular Research, Inc. 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
CA2415532C (en) * 2000-07-11 2010-05-11 Albany Molecular Research, Inc. Novel 4-phenyl substituted tetrahydroisoquinolines therapeutic use thereof
WO2006020049A2 (en) 2004-07-15 2006-02-23 Amr Technology, Inc. Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
CN101243083A (zh) 2005-06-17 2008-08-13 詹森药业有限公司 萘啶化合物
CN101495184A (zh) 2005-07-15 2009-07-29 Amr科技公司 芳基和杂芳基取代的四氢苯并氮杂及其在阻断去甲肾上腺素多巴胺和血清素的重摄取中的应用
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
KR20120034644A (ko) 2009-05-12 2012-04-12 알바니 몰레큘라 리써치, 인크. 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
US8815894B2 (en) 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
DK2429296T3 (en) 2009-05-12 2018-03-12 Albany Molecular Res Inc 7 - ([1,2,4,] TRIAZOLO [1,5, -A] PYRIDIN-6-YL) -4- (3,4-DICHLORPHENYL) -1,2,3,4- TETRAHYDROISOQUINOLINE AND USE thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
DK125021B (da) 1972-12-18
IE34859B1 (en) 1975-09-03
CH527194A (de) 1972-08-31
ES387016A1 (es) 1976-05-01
NL171444C (nl) 1983-04-05
YU33660B (en) 1977-12-31
NL7018956A (instruction) 1971-07-08
ZA708590B (en) 1971-09-29
PH9682A (en) 1976-02-10
JPS5515476B1 (instruction) 1980-04-23
CH538477A (de) 1973-06-30
FR2081412B1 (instruction) 1974-04-12
FI49503C (fi) 1975-07-10
IL35916A0 (en) 1971-02-25
IE34859L (en) 1971-07-06
NO135315C (instruction) 1977-03-23
GB1335261A (en) 1973-10-24
BE761219A (fr) 1971-07-05
NL171444B (nl) 1982-11-01
DE2062001C2 (de) 1986-10-16
YU1971A (en) 1977-06-30
CA999866A (en) 1976-11-16
DE2062001A1 (de) 1971-07-15
SE368401B (instruction) 1974-07-01
AT303041B (de) 1972-11-10
NO135315B (instruction) 1976-12-13
FI49503B (instruction) 1975-04-01
FR2081412A1 (instruction) 1971-12-03
SE386672B (sv) 1976-08-16
SE399879B (sv) 1978-03-06

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