IL258158B2 - Compounds for the use of profortin in the prevention and/or treatment of iron metabolism disorders - Google Patents
Compounds for the use of profortin in the prevention and/or treatment of iron metabolism disordersInfo
- Publication number
- IL258158B2 IL258158B2 IL258158A IL25815818A IL258158B2 IL 258158 B2 IL258158 B2 IL 258158B2 IL 258158 A IL258158 A IL 258158A IL 25815818 A IL25815818 A IL 25815818A IL 258158 B2 IL258158 B2 IL 258158B2
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- Israel
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- compound
- exp
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- compounds
- formula
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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| PT2968443T (pt) | 2013-03-15 | 2021-12-28 | Protagonist Therapeutics Inc | Análogos de hepcidina e seus usos |
| JP6810988B2 (ja) * | 2015-10-23 | 2021-01-13 | ヴィフォール (インターナショナル) アクチェンゲゼルシャフトVifor (International) AG | 新規なフェロポーチン阻害剤 |
| JOP20180036A1 (ar) * | 2017-04-18 | 2019-01-30 | Vifor Int Ag | أملاح لمثبطات فروبورتين جديدة |
| CN108314687A (zh) * | 2017-12-27 | 2018-07-24 | 重庆文理学院 | 1,2-二氢苯并[4,5]咪唑并[1,2-a]吡嗪-3(4H)-酮衍生物的合成 |
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| EP3788065B1 (en) | 2018-04-30 | 2025-08-27 | The Children's Hospital Of Philadelphia | Improving anemias by combining agents |
| EP3894416B1 (en) | 2018-12-13 | 2022-11-09 | Global Blood Therapeutics, Inc. | Ferroportin inhibitors and methods of use |
| TW202102478A (zh) | 2019-04-01 | 2021-01-16 | 瑞士商威佛(國際)股份有限公司 | 新穎的鐵螯合物 |
| US20220273634A1 (en) * | 2019-07-19 | 2022-09-01 | Vifor (International) Ag | Ferroportin-Inhibitors For The Use In The Treatment Of Transfusion-Dependent Beta-Thalassemia (TDT) |
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| EP3782702A1 (en) * | 2019-08-21 | 2021-02-24 | AC BioScience SA | Compounds and use thereof for the treatment of infectious diseases and cancer |
| BR112022003999A2 (pt) | 2019-09-03 | 2022-05-31 | Protagonist Therapeutics Inc | Miméticos de hepcidina conjugados |
| CA3154524A1 (en) | 2019-10-22 | 2021-04-21 | Vania Manolova | Methods and compositions for treating sickle cell disease with a ferroportin inhibitor (vit-2763) |
| CN115362154A (zh) * | 2020-03-24 | 2022-11-18 | 威佛(国际)股份公司 | 膜铁转运蛋白抑制剂的制备方法 |
| GB202012969D0 (en) * | 2020-08-19 | 2020-09-30 | Univ Of Oxford | Inhibitor compounds |
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| WO2022173818A1 (en) * | 2021-02-09 | 2022-08-18 | University Of Virginia Patent Foundation | Use of biliverdin reductase b inhibitors to allow malaria eradication in patients with g6pd deficiency |
| KR20230163464A (ko) * | 2021-03-26 | 2023-11-30 | 키에시 파르마슈티시 엣스. 피. 에이. | Ddr 억제제로서 테트라하이드로싸이에노 피리딘 유도체 |
| TW202304896A (zh) | 2021-04-22 | 2023-02-01 | 瑞士商威佛(國際)股份有限公司 | 經修飾的膜鐵運輸蛋白(ferroportin)抑制劑 |
| JP2024534538A (ja) | 2021-09-21 | 2024-09-20 | ビフォー (インターナショナル) エージー | N-置換フェロポーチン阻害剤 |
| CN120322439A (zh) | 2022-10-21 | 2025-07-15 | 威佛(国际)股份公司 | 双环铁转运蛋白抑制剂 |
| CN115974864B (zh) * | 2022-12-29 | 2025-09-16 | 苏州汉德创宏生化科技有限公司 | 一种2-(3-氮杂环丁基)噻唑盐的合成方法 |
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