WO2008123093A1 - 鉄過剰症の予防または治療剤 - Google Patents

鉄過剰症の予防または治療剤 Download PDF

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Publication number
WO2008123093A1
WO2008123093A1 PCT/JP2008/055060 JP2008055060W WO2008123093A1 WO 2008123093 A1 WO2008123093 A1 WO 2008123093A1 JP 2008055060 W JP2008055060 W JP 2008055060W WO 2008123093 A1 WO2008123093 A1 WO 2008123093A1
Authority
WO
WIPO (PCT)
Prior art keywords
prevention
agent
treatment
iron overload
overload
Prior art date
Application number
PCT/JP2008/055060
Other languages
English (en)
French (fr)
Inventor
Hideaki Kagehara
Shoji Nishiyama
Original Assignee
Meiji Seika Kaisha, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha, Ltd. filed Critical Meiji Seika Kaisha, Ltd.
Priority to US12/532,361 priority Critical patent/US20100093871A1/en
Priority to JP2009509043A priority patent/JPWO2008123093A1/ja
Priority to EP08738668A priority patent/EP2128171A1/en
Publication of WO2008123093A1 publication Critical patent/WO2008123093A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Abstract

　２２β－メトキシオレアン－１２－エン－３β，２４（４β）－ジオール又はその薬理学的に許容される塩を含んでなる、鉄過剰症の予防又は治療剤を開示する。
PCT/JP2008/055060 2007-03-20 2008-03-19 鉄過剰症の予防または治療剤 WO2008123093A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/532,361 US20100093871A1 (en) 2007-03-20 2008-03-19 Agent for prevention or treatment of iron overload disorders
JP2009509043A JPWO2008123093A1 (ja) 2007-03-20 2008-03-19 鉄過剰症の予防または治療剤
EP08738668A EP2128171A1 (en) 2007-03-20 2008-03-19 Agent for prevention or treatment of iron overload

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007071877 2007-03-20
JP2007-071877 2007-03-20

Publications (1)

Publication Number Publication Date
WO2008123093A1 true WO2008123093A1 (ja) 2008-10-16

Family

ID=39830594

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/055060 WO2008123093A1 (ja) 2007-03-20 2008-03-19 鉄過剰症の予防または治療剤

Country Status (5)

Country Link
US (1) US20100093871A1 (ja)
EP (1) EP2128171A1 (ja)
JP (1) JPWO2008123093A1 (ja)
CN (1) CN101646686A (ja)
WO (1) WO2008123093A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010087447A1 (ja) * 2009-01-30 2010-08-05 明治製菓株式会社 微粉砕医薬組成物
WO2017068089A2 (en) 2015-10-23 2017-04-27 Vifor (International) Ag Novel ferroportin inhibitors
WO2018192973A1 (en) 2017-04-18 2018-10-25 Vifor (International) Ag Ferroportin-inhibitor salts
WO2020201305A1 (en) 2019-04-01 2020-10-08 Vifor (International) Ag 4-(2,4-bis(2-hydroxyphenyl)-1h-imidazol-1-yl)benzoic acid derivatives as novel iron chelators

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3203991A4 (en) * 2014-10-10 2018-06-20 The Board of Regents of The University of Texas System Hif-2 inhibitors for treating iron overload disorders
TW201739448A (zh) * 2016-05-06 2017-11-16 安成生物科技股份有限公司 用於治療及/或預防血液相關疾病之方法及配方

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997003088A1 (fr) 1995-07-07 1997-01-30 Meiji Seika Kabushiki Kaisha Derives triterpenes et medicament pour les maladies du foie

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997003088A1 (fr) 1995-07-07 1997-01-30 Meiji Seika Kabushiki Kaisha Derives triterpenes et medicament pour les maladies du foie
JP3279574B2 (ja) 1995-07-07 2002-04-30 明治製菓株式会社 トリテルペン誘導体および肝疾患治療剤

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
"STEDMAN'S Medical Dictionary", 1998, MEDICAL VIEW CO., LTD.
MARK H. BEERS; MASANORI FUKUSHIMA: "The Merck Manual", 10 December 1999, NIKKEI BUSINESS PUBLICATIONS, INC., pages: 883 - 885
MASAAKI TAKAHASHI: "Transfusional Iron Overload disorder and Iron Chelation Therapy", SAISHIN IGAKU, vol. 61, no. 3, March 2006 (2006-03-01), pages 453 - 457
SAISHIN IGAKU, vol. 61, no. 3, 2006, pages 453 - 457
TAKATOKU M.: "Yuketsugo Tetsu Kajosho to Keiko Tetsu Chelating Agent", SAISHIN IGAKU, vol. 61, no. 3, March 2006 (2006-03-01), pages 107(453) - 111(457), XP008133970 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010087447A1 (ja) * 2009-01-30 2010-08-05 明治製菓株式会社 微粉砕医薬組成物
CN102365098A (zh) * 2009-01-30 2012-02-29 明治制果药业株式会社 细粉状药物组合物
WO2017068089A2 (en) 2015-10-23 2017-04-27 Vifor (International) Ag Novel ferroportin inhibitors
WO2018192973A1 (en) 2017-04-18 2018-10-25 Vifor (International) Ag Ferroportin-inhibitor salts
WO2020201305A1 (en) 2019-04-01 2020-10-08 Vifor (International) Ag 4-(2,4-bis(2-hydroxyphenyl)-1h-imidazol-1-yl)benzoic acid derivatives as novel iron chelators

Also Published As

Publication number Publication date
CN101646686A (zh) 2010-02-10
US20100093871A1 (en) 2010-04-15
JPWO2008123093A1 (ja) 2010-07-15
EP2128171A1 (en) 2009-12-02

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