IL254384A0 - Acetate salt of buprenorphine and methods of preparing buprenorphine - Google Patents
Acetate salt of buprenorphine and methods of preparing buprenorphineInfo
- Publication number
- IL254384A0 IL254384A0 IL254384A IL25438417A IL254384A0 IL 254384 A0 IL254384 A0 IL 254384A0 IL 254384 A IL254384 A IL 254384A IL 25438417 A IL25438417 A IL 25438417A IL 254384 A0 IL254384 A0 IL 254384A0
- Authority
- IL
- Israel
- Prior art keywords
- buprenorphine
- methods
- acetate salt
- preparing
- acetate
- Prior art date
Links
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 title 2
- 229960001736 buprenorphine Drugs 0.000 title 2
- 159000000021 acetate salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
- C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
- C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562131114P | 2015-03-10 | 2015-03-10 | |
| PCT/IB2016/051332 WO2016142877A1 (en) | 2015-03-10 | 2016-03-09 | Acetate salt of buprenorphine and methods for preparing buprenorphine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL254384A0 true IL254384A0 (en) | 2017-11-30 |
Family
ID=55524412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL254384A IL254384A0 (en) | 2015-03-10 | 2017-09-07 | Acetate salt of buprenorphine and methods of preparing buprenorphine |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US10406152B2 (enExample) |
| EP (1) | EP3283490A1 (enExample) |
| JP (2) | JP6660399B2 (enExample) |
| KR (2) | KR20200045010A (enExample) |
| CN (1) | CN107660207B (enExample) |
| AR (1) | AR103902A1 (enExample) |
| AU (2) | AU2016230750B2 (enExample) |
| BR (1) | BR112017019357A2 (enExample) |
| CA (2) | CA2977732C (enExample) |
| CO (1) | CO2017009130A2 (enExample) |
| EA (1) | EA201792014A1 (enExample) |
| IL (1) | IL254384A0 (enExample) |
| MA (1) | MA45902A (enExample) |
| MX (1) | MX2017011606A (enExample) |
| NZ (1) | NZ735736A (enExample) |
| PH (1) | PH12017501641A1 (enExample) |
| SG (1) | SG11201707350TA (enExample) |
| TW (2) | TW202037597A (enExample) |
| WO (1) | WO2016142877A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016512046A (ja) | 2013-03-15 | 2016-04-25 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ベンジルイソキノリンアルカロイド（ｂｉａ）産生微生物、ならびにそれらを作製および使用する方法 |
| US11124814B2 (en) | 2013-11-04 | 2021-09-21 | The Board Of Trustees Of The Leland Stanford Junior University | Benzylisoquinoline alkaloid (BIA) precursor producing microbes, and methods of making and using the same |
| SG11201707350TA (en) * | 2015-03-10 | 2017-10-30 | Rhodes Tech | Acetate salt of buprenorphine and methods for preparing buprenorphine |
| CN107614688B (zh) | 2015-05-04 | 2023-02-28 | 小利兰·斯坦福大学托管委员会 | 产生苄基异喹啉生物碱(bia)前体的微生物及其制备和使用方法 |
| JP7266966B2 (ja) | 2015-05-08 | 2023-05-01 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | エピメラーゼ及びベンジルイソキノリンアルカロイドを産生する方法 |
| EP3529355A4 (en) | 2016-10-18 | 2020-07-08 | Antheia, Inc. | PROCESSES FOR THE PRODUCTION OF NOR-OPIOID AND NAL-OPIOID BENZYLISOQUINOLINE ALKALOIDS |
| JP7199417B2 (ja) | 2017-08-03 | 2023-01-05 | アンテイア インコーポレイテッド | 遺伝子操作されたベンジルイソキノリンアルカロイドエピメラーゼおよびベンジルイソキノリンアルカロイドの生成方法 |
| KR102839314B1 (ko) * | 2018-05-11 | 2025-07-29 | 에일러 파마슈티컬스 아이엔씨. | 오래 지속되는 주사용 제제와 부프레노핀 유도체 |
| KR20210138642A (ko) | 2019-03-08 | 2021-11-19 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 비-식물 숙주 세포를 생산하는 트로판 알칼로이드(ta), 및 이의 제조 및 사용 방법 |
| CN119421713A (zh) * | 2022-06-24 | 2025-02-11 | 昱展新药生技股份有限公司 | 丁丙诺啡的稳定医药组合物、其制备方法及其用途 |
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| SG11201707350TA (en) * | 2015-03-10 | 2017-10-30 | Rhodes Tech | Acetate salt of buprenorphine and methods for preparing buprenorphine |
-
2016
- 2016-03-09 SG SG11201707350TA patent/SG11201707350TA/en unknown
- 2016-03-09 CA CA2977732A patent/CA2977732C/en not_active Expired - Fee Related
- 2016-03-09 MA MA045902A patent/MA45902A/fr unknown
- 2016-03-09 US US15/507,453 patent/US10406152B2/en active Active
- 2016-03-09 EA EA201792014A patent/EA201792014A1/ru unknown
- 2016-03-09 CN CN201680027202.2A patent/CN107660207B/zh not_active Expired - Fee Related
- 2016-03-09 NZ NZ735736A patent/NZ735736A/en not_active IP Right Cessation
- 2016-03-09 MX MX2017011606A patent/MX2017011606A/es unknown
- 2016-03-09 BR BR112017019357A patent/BR112017019357A2/pt not_active IP Right Cessation
- 2016-03-09 CA CA3104099A patent/CA3104099A1/en not_active Abandoned
- 2016-03-09 WO PCT/IB2016/051332 patent/WO2016142877A1/en not_active Ceased
- 2016-03-09 KR KR1020207011729A patent/KR20200045010A/ko not_active Ceased
- 2016-03-09 KR KR1020177028535A patent/KR20170137738A/ko not_active Ceased
- 2016-03-09 EP EP16709607.2A patent/EP3283490A1/en not_active Withdrawn
- 2016-03-09 JP JP2017547399A patent/JP6660399B2/ja not_active Expired - Fee Related
- 2016-03-09 AU AU2016230750A patent/AU2016230750B2/en not_active Ceased
- 2016-03-10 TW TW109106564A patent/TW202037597A/zh unknown
- 2016-03-10 AR ARP160100641A patent/AR103902A1/es unknown
- 2016-03-10 TW TW105107434A patent/TWI699367B/zh not_active IP Right Cessation
-
2017
- 2017-03-01 US US15/446,197 patent/US9926329B2/en active Active
- 2017-09-07 CO CONC2017/0009130A patent/CO2017009130A2/es unknown
- 2017-09-07 IL IL254384A patent/IL254384A0/en unknown
- 2017-09-08 PH PH12017501641A patent/PH12017501641A1/en unknown
-
2018
- 2018-02-12 US US15/894,520 patent/US10278967B2/en active Active
-
2019
- 2019-05-10 AU AU2019203308A patent/AU2019203308A1/en not_active Abandoned
- 2019-06-19 US US16/446,373 patent/US10835528B2/en active Active
- 2019-06-19 US US16/446,397 patent/US10874662B2/en active Active
- 2019-10-10 JP JP2019186901A patent/JP2020033359A/ja active Pending
-
2020
- 2020-10-29 US US17/084,588 patent/US20210046066A1/en not_active Abandoned
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