MX2017011606A - Metodos para preparar buprenorfina. - Google Patents

Metodos para preparar buprenorfina.

Info

Publication number
MX2017011606A
MX2017011606A MX2017011606A MX2017011606A MX2017011606A MX 2017011606 A MX2017011606 A MX 2017011606A MX 2017011606 A MX2017011606 A MX 2017011606A MX 2017011606 A MX2017011606 A MX 2017011606A MX 2017011606 A MX2017011606 A MX 2017011606A
Authority
MX
Mexico
Prior art keywords
buprenorphine
preparing
methods
acetate salt
acetate salts
Prior art date
Application number
MX2017011606A
Other languages
English (en)
Spanish (es)
Inventor
Frederick M Huntley C
Wayne Kataisto Erik
Alfred REISCH Helge
Sharma Archana
Larry STYMIEST Jake
Original Assignee
Rhodes Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodes Tech filed Critical Rhodes Tech
Publication of MX2017011606A publication Critical patent/MX2017011606A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
MX2017011606A 2015-03-10 2016-03-09 Metodos para preparar buprenorfina. MX2017011606A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562131114P 2015-03-10 2015-03-10
PCT/IB2016/051332 WO2016142877A1 (en) 2015-03-10 2016-03-09 Acetate salt of buprenorphine and methods for preparing buprenorphine

Publications (1)

Publication Number Publication Date
MX2017011606A true MX2017011606A (es) 2017-10-26

Family

ID=55524412

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011606A MX2017011606A (es) 2015-03-10 2016-03-09 Metodos para preparar buprenorfina.

Country Status (19)

Country Link
US (6) US10406152B2 (enExample)
EP (1) EP3283490A1 (enExample)
JP (2) JP6660399B2 (enExample)
KR (2) KR20200045010A (enExample)
CN (1) CN107660207B (enExample)
AR (1) AR103902A1 (enExample)
AU (2) AU2016230750B2 (enExample)
BR (1) BR112017019357A2 (enExample)
CA (2) CA2977732C (enExample)
CO (1) CO2017009130A2 (enExample)
EA (1) EA201792014A1 (enExample)
IL (1) IL254384A0 (enExample)
MA (1) MA45902A (enExample)
MX (1) MX2017011606A (enExample)
NZ (1) NZ735736A (enExample)
PH (1) PH12017501641A1 (enExample)
SG (1) SG11201707350TA (enExample)
TW (2) TW202037597A (enExample)
WO (1) WO2016142877A1 (enExample)

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JP2016512046A (ja) 2013-03-15 2016-04-25 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー ベンジルイソキノリンアルカロイド（ｂｉａ）産生微生物、ならびにそれらを作製および使用する方法
US11124814B2 (en) 2013-11-04 2021-09-21 The Board Of Trustees Of The Leland Stanford Junior University Benzylisoquinoline alkaloid (BIA) precursor producing microbes, and methods of making and using the same
SG11201707350TA (en) * 2015-03-10 2017-10-30 Rhodes Tech Acetate salt of buprenorphine and methods for preparing buprenorphine
CN107614688B (zh) 2015-05-04 2023-02-28 小利兰·斯坦福大学托管委员会 产生苄基异喹啉生物碱(bia)前体的微生物及其制备和使用方法
JP7266966B2 (ja) 2015-05-08 2023-05-01 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー エピメラーゼ及びベンジルイソキノリンアルカロイドを産生する方法
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KR102839314B1 (ko) * 2018-05-11 2025-07-29 에일러 파마슈티컬스 아이엔씨. 오래 지속되는 주사용 제제와 부프레노핀 유도체
KR20210138642A (ko) 2019-03-08 2021-11-19 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 비-식물 숙주 세포를 생산하는 트로판 알칼로이드(ta), 및 이의 제조 및 사용 방법
CN119421713A (zh) * 2022-06-24 2025-02-11 昱展新药生技股份有限公司 丁丙诺啡的稳定医药组合物、其制备方法及其用途

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Also Published As

Publication number Publication date
CO2017009130A2 (es) 2017-11-21
US20180162866A1 (en) 2018-06-14
AU2016230750B2 (en) 2019-05-30
TWI699367B (zh) 2020-07-21
US9926329B2 (en) 2018-03-27
US10874662B2 (en) 2020-12-29
EP3283490A1 (en) 2018-02-21
US20210046066A1 (en) 2021-02-18
MA45902A (fr) 2019-06-19
JP6660399B2 (ja) 2020-03-11
AU2019203308A1 (en) 2019-05-30
CA2977732C (en) 2021-02-23
JP2018507882A (ja) 2018-03-22
NZ735736A (en) 2019-02-22
US20190314364A1 (en) 2019-10-17
TW202037597A (zh) 2020-10-16
TW201639856A (zh) 2016-11-16
PH12017501641A1 (en) 2018-02-12
US10406152B2 (en) 2019-09-10
US20180235955A1 (en) 2018-08-23
AR103902A1 (es) 2017-06-14
US20190298713A1 (en) 2019-10-03
CN107660207A (zh) 2018-02-02
CA3104099A1 (en) 2016-09-15
AU2016230750A1 (en) 2017-10-12
KR20200045010A (ko) 2020-04-29
US20170197975A1 (en) 2017-07-13
CA2977732A1 (en) 2016-09-15
CN107660207B (zh) 2020-09-29
WO2016142877A1 (en) 2016-09-15
SG11201707350TA (en) 2017-10-30
US10835528B2 (en) 2020-11-17
IL254384A0 (en) 2017-11-30
JP2020033359A (ja) 2020-03-05
US10278967B2 (en) 2019-05-07
EA201792014A1 (ru) 2018-01-31
BR112017019357A2 (pt) 2018-06-05
KR20170137738A (ko) 2017-12-13

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