AR089201A1 - Sistema de suministro transdermico - Google Patents

Sistema de suministro transdermico

Info

Publication number
AR089201A1
AR089201A1 ARP120104673A ARP120104673A AR089201A1 AR 089201 A1 AR089201 A1 AR 089201A1 AR P120104673 A ARP120104673 A AR P120104673A AR P120104673 A ARP120104673 A AR P120104673A AR 089201 A1 AR089201 A1 AR 089201A1
Authority
AR
Argentina
Prior art keywords
buprenorphine
adhesive layer
acid
pressure
sensitive adhesive
Prior art date
Application number
ARP120104673A
Other languages
English (en)
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47754872&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR089201(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of AR089201A1 publication Critical patent/AR089201A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Abstract

Un sistema terapéutico transdérmico para la administración transdérmica de buprenorfina, que comprende una estructura de capa autoadhesiva que contiene buprenorfina que comprende A) una capa de refuerzo impermeable de buprenorfina, y B) una capa adhesiva sensible a la presión que contiene buprenorfina en dicha capa de refuerzo impermeable de buprenorfina, donde la capa adhesiva comprende a) al menos un adhesivo sensible a la presión en base a polímero, b) una cantidad analgésicamente efectiva de buprenorfina base o una sal farmacéuticamente aceptable de la misma, y c) un ácido carboxílico seleccionado del grupo que consiste en ácido oleico, ácido linoleico y ácido linolénico, ácido levulínico y mezclas de los mismos, en una cantidad suficiente de manera que dicha cantidad analgésicamente efectiva de buprenorfina sea solubilizada en éste para formar una mezcla y la mezcla de buprenorfina en ácido carboxílico forme depósitos dispersos en dicho adhesivo sensible a la presión, donde dicha capa adhesiva sensible a la presión que contiene buprenorfina es la capa en contacto con la piel y métodos de elaboración del mismo.
ARP120104673A 2011-12-12 2012-12-12 Sistema de suministro transdermico AR089201A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161569609P 2011-12-12 2011-12-12

Publications (1)

Publication Number Publication Date
AR089201A1 true AR089201A1 (es) 2014-08-06

Family

ID=47754872

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120104673A AR089201A1 (es) 2011-12-12 2012-12-12 Sistema de suministro transdermico

Country Status (27)

Country Link
US (4) US20140363487A1 (es)
EP (1) EP2790685B1 (es)
JP (2) JP6289378B2 (es)
KR (1) KR102014565B1 (es)
CN (2) CN107669662A (es)
AP (1) AP4036A (es)
AR (1) AR089201A1 (es)
AU (1) AU2012327247B2 (es)
BR (1) BR112014014137A2 (es)
CA (1) CA2858531C (es)
CL (1) CL2014001559A1 (es)
CO (1) CO7000779A2 (es)
CR (1) CR20140321A (es)
DE (1) DE112012005185T5 (es)
EA (1) EA201491164A1 (es)
ES (1) ES2647516T3 (es)
GB (1) GB2512007B8 (es)
HK (2) HK1201760A1 (es)
IL (1) IL233025A0 (es)
MX (1) MX352795B (es)
PE (1) PE20142341A1 (es)
PH (1) PH12014501231A1 (es)
PL (1) PL2790685T3 (es)
SG (2) SG11201403162XA (es)
TN (1) TN2014000233A1 (es)
TW (1) TW201338813A (es)
WO (1) WO2013088254A1 (es)

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Also Published As

Publication number Publication date
CL2014001559A1 (es) 2014-10-03
MX2014007020A (es) 2014-07-14
GB2512007A8 (en) 2017-06-28
AU2012327247A1 (en) 2013-06-27
GB2512007B8 (en) 2017-06-28
JP2015500329A (ja) 2015-01-05
PL2790685T3 (pl) 2018-04-30
TN2014000233A1 (en) 2015-09-30
ES2647516T3 (es) 2017-12-22
SG11201403162XA (en) 2014-10-30
AU2012327247B2 (en) 2015-12-24
EP2790685A1 (en) 2014-10-22
SG10201604754VA (en) 2016-08-30
HK1203048A1 (en) 2015-10-16
EP2790685B1 (en) 2017-08-16
CA2858531A1 (en) 2013-06-20
NZ626535A (en) 2017-02-24
GB2512007A (en) 2014-09-17
GB2512007B (en) 2017-04-26
US20140363487A1 (en) 2014-12-11
US20170049713A1 (en) 2017-02-23
AP2014007779A0 (en) 2014-07-31
CR20140321A (es) 2014-11-13
US20200306204A1 (en) 2020-10-01
CN104114161A (zh) 2014-10-22
WO2013088254A1 (en) 2013-06-20
JP2017036304A (ja) 2017-02-16
CA2858531C (en) 2019-12-17
CN107669662A (zh) 2018-02-09
MX352795B (es) 2017-12-07
CO7000779A2 (es) 2014-07-21
GB201412385D0 (en) 2014-08-27
PE20142341A1 (es) 2015-01-17
EA201491164A1 (ru) 2014-10-30
IL233025A0 (en) 2014-07-31
HK1201760A1 (en) 2015-09-11
JP6289378B2 (ja) 2018-03-07
PH12014501231A1 (en) 2014-09-08
TW201338813A (zh) 2013-10-01
AP4036A (en) 2017-02-22
US20160120823A1 (en) 2016-05-05
KR102014565B1 (ko) 2019-08-26
KR20140101858A (ko) 2014-08-20
US9549903B2 (en) 2017-01-24
BR112014014137A2 (pt) 2017-06-13
DE112012005185T5 (de) 2014-08-28

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