IL164844A - Method for albumin purification - Google Patents

Method for albumin purification

Info

Publication number
IL164844A
IL164844A IL164844A IL16484404A IL164844A IL 164844 A IL164844 A IL 164844A IL 164844 A IL164844 A IL 164844A IL 16484404 A IL16484404 A IL 16484404A IL 164844 A IL164844 A IL 164844A
Authority
IL
Israel
Prior art keywords
matrix
rhsa
cation exchange
bimodal
cell culture
Prior art date
Application number
IL164844A
Other languages
English (en)
Other versions
IL164844A0 (en
Original Assignee
Ge Healthcare Bio Sciences Ab
North China Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences Ab, North China Pharmaceutical filed Critical Ge Healthcare Bio Sciences Ab
Publication of IL164844A0 publication Critical patent/IL164844A0/xx
Publication of IL164844A publication Critical patent/IL164844A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL164844A 2002-05-15 2004-10-26 Method for albumin purification IL164844A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0201518A SE526227C2 (sv) 2002-05-15 2002-05-15 Metod för rening av rekombinant humant serumalbumin
PCT/SE2003/000766 WO2003097692A1 (en) 2002-05-15 2003-05-09 Method for albumin purification

Publications (2)

Publication Number Publication Date
IL164844A0 IL164844A0 (en) 2005-12-18
IL164844A true IL164844A (en) 2009-09-01

Family

ID=20287916

Family Applications (1)

Application Number Title Priority Date Filing Date
IL164844A IL164844A (en) 2002-05-15 2004-10-26 Method for albumin purification

Country Status (13)

Country Link
US (2) US7423124B2 (cg-RX-API-DMAC7.html)
EP (2) EP1504031B1 (cg-RX-API-DMAC7.html)
JP (2) JP2006502098A (cg-RX-API-DMAC7.html)
CN (1) CN100463921C (cg-RX-API-DMAC7.html)
AT (1) ATE335006T1 (cg-RX-API-DMAC7.html)
AU (2) AU2003228193B2 (cg-RX-API-DMAC7.html)
BR (2) BRPI0309992B8 (cg-RX-API-DMAC7.html)
CA (2) CA2483612A1 (cg-RX-API-DMAC7.html)
DE (1) DE60307262T2 (cg-RX-API-DMAC7.html)
ES (1) ES2268362T3 (cg-RX-API-DMAC7.html)
IL (1) IL164844A (cg-RX-API-DMAC7.html)
SE (1) SE526227C2 (cg-RX-API-DMAC7.html)
WO (2) WO2003097692A1 (cg-RX-API-DMAC7.html)

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US8802146B2 (en) * 1998-11-06 2014-08-12 Neomend, Inc. Systems, methods, and compositions for prevention of tissue adhesion
RU2343151C3 (ru) * 2003-01-28 2019-10-01 ЭфЭмСи Корпорейшн Цианоантраниламидные инсектициды
JP2006522752A (ja) * 2003-03-12 2006-10-05 フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 肝不全後の透析における組換えアルブミンの使用
CA2564031A1 (en) * 2004-04-23 2005-11-03 Conjuchem Biotechnologies Inc. Method for the purification of albumin conjugates
CN1854155B (zh) * 2005-04-29 2010-11-17 华北制药集团新药研究开发有限责任公司 一种纯化rHSA的方法
AR067537A1 (es) * 2007-07-17 2009-10-14 Hoffmann La Roche Purificacion de polipeptidos pegilados
CL2008002054A1 (es) * 2007-07-17 2009-05-29 Hoffmann La Roche Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico.
JP4452324B2 (ja) * 2008-03-31 2010-04-21 積水メディカル株式会社 精製血清アルブミン及び免疫学的測定方法
US8753868B2 (en) 2008-08-04 2014-06-17 General Electric Company Method and system for selective isolation of target biological molecules in a general purpose system
CN101768206B (zh) * 2008-12-31 2013-05-15 华北制药集团新药研究开发有限责任公司 一种重组人血清白蛋白的纯化方法及其应用
US20120315697A1 (en) 2009-02-20 2012-12-13 Ventria Bioscience Cell Culture Media Containing Combinations of Proteins
SI2575847T2 (sl) * 2010-05-25 2022-08-31 F. Hoffmann-La Roche Ag Tehnike čiščenja polipeptidov
CN102127164B (zh) 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) * 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
CN104812491B (zh) * 2012-03-08 2018-06-19 生物辐射实验室股份有限公司 阴离子交换-疏水性混合模式
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
CN103923211A (zh) * 2014-05-08 2014-07-16 齐智 一种医药级重组人血清白蛋白的纯化方法
CN107709552B (zh) 2015-06-10 2022-05-13 南克维斯特公司 用于治疗癌症的修饰的nk-92细胞
CN106117326A (zh) * 2015-12-09 2016-11-16 烟台大学 一种离心法结合阴离子交换层析介质制备藻红蛋白的方法
CN106146631A (zh) * 2015-12-09 2016-11-23 烟台大学 一种离心技术结合疏水层析介质制备藻红蛋白的方法
CN106117347A (zh) * 2015-12-09 2016-11-16 烟台大学 一种疏水层析制备高纯度藻红蛋白的方法
KR20220066393A (ko) 2019-09-24 2022-05-24 리제너론 파아마슈티컬스, 인크. 크로마토그래피의 사용 및 재생을 위한 시스템 및 방법
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
US20230331772A1 (en) 2020-12-08 2023-10-19 Tonghua Anrate Biopharmaceutical Co., Ltd Method for purification of recombinant proteins
WO2022146917A1 (en) 2020-12-28 2022-07-07 Davol Inc. Reactive dry powdered hemostatic materials comprising a protein and a multifunctionalized modified polyethylene glycol based crosslinking agent
CN113461804A (zh) * 2021-08-09 2021-10-01 山东健通生物科技有限公司 减少重组人血白蛋白发酵过程中色素的方法
CN113880908B (zh) * 2021-08-25 2024-05-14 北京伟德杰生物科技有限公司 纯化重组人血清白蛋白的融合蛋白的方法
CN113735962B (zh) * 2021-08-27 2023-11-10 常熟纳微生物科技有限公司 一种从猪血中纯化重组人血清白蛋白的方法及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093612A (en) * 1975-08-04 1978-06-06 Research Corporation Selective removal of albumin from blood fluids and compositions therefore
FR2403098A1 (fr) * 1977-09-19 1979-04-13 Merieux Inst Nouveau materiau capable de fixer de facon reversible des macromolecules biologiques, sa preparation et son application
EP0933083A1 (en) * 1991-07-12 1999-08-04 Dsm N.V. Process for the purification of serum albumin
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
JPH07102148B2 (ja) * 1992-05-20 1995-11-08 株式会社ミドリ十字 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
CA2116385A1 (en) * 1993-02-25 1994-08-26 Akinori Sumi Human serum albumin and process for producing the same
DK0658569T3 (da) * 1993-12-17 2005-02-07 Mitsubishi Pharma Corp Fremgangsmåde til affarvning af humant serumalbumin
JP3840674B2 (ja) * 1994-08-31 2006-11-01 三菱ウェルファーマ株式会社 遺伝子操作に由来するヒト血清アルブミンの精製方法
DK0699687T3 (da) * 1994-08-31 2004-04-26 Mitsubishi Pharma Corp Fremgangsmåde til oprensning af rekombinant humant serumalbumin
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
SE0002688D0 (sv) * 2000-07-17 2000-07-17 Amersham Pharm Biotech Ab Adsorption method and ligands
JP4798832B2 (ja) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法

Also Published As

Publication number Publication date
ATE335006T1 (de) 2006-08-15
US20050215765A1 (en) 2005-09-29
JP2006512283A (ja) 2006-04-13
DE60307262T2 (de) 2007-06-28
SE0201518D0 (sv) 2002-05-15
EP1504031A1 (en) 2005-02-09
IL164844A0 (en) 2005-12-18
WO2003097693A1 (en) 2003-11-27
BR0309992A (pt) 2005-03-01
BRPI0309992B1 (pt) 2020-12-22
US7351801B2 (en) 2008-04-01
EP1504031B1 (en) 2006-08-02
AU2003228193B2 (en) 2009-05-07
DE60307262D1 (de) 2006-09-14
AU2003228193A1 (en) 2003-12-02
EP1504032A1 (en) 2005-02-09
SE526227C2 (sv) 2005-08-02
CN100463921C (zh) 2009-02-25
JP2006502098A (ja) 2006-01-19
CN1496993A (zh) 2004-05-19
WO2003097692A1 (en) 2003-11-27
US7423124B2 (en) 2008-09-09
BRPI0309992B8 (pt) 2023-03-21
ES2268362T3 (es) 2007-03-16
US20050214902A1 (en) 2005-09-29
CA2483616A1 (en) 2003-11-27
AU2003232704A1 (en) 2003-12-02
CA2483612A1 (en) 2003-11-27
JP4559216B2 (ja) 2010-10-06

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Legal Events

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