BR0215585A - Processo de produção de fator de desenvolvimento placentário - Google Patents

Processo de produção de fator de desenvolvimento placentário

Info

Publication number
BR0215585A
BR0215585A BR0215585-0A BR0215585A BR0215585A BR 0215585 A BR0215585 A BR 0215585A BR 0215585 A BR0215585 A BR 0215585A BR 0215585 A BR0215585 A BR 0215585A
Authority
BR
Brazil
Prior art keywords
development factor
production process
factor production
placental development
purification
Prior art date
Application number
BR0215585-0A
Other languages
English (en)
Inventor
Domenico Maglione
Mauri Battisiti
Ettore Conti
Guiseppe Salvia
Marina Tucci
Original Assignee
Geymonat Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27676896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0215585(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geymonat Spa filed Critical Geymonat Spa
Publication of BR0215585A publication Critical patent/BR0215585A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"PROCESSO DE PRODUçãO DE FATOR DE DESENVOLVIMENTO PLACENTáRIO". Processo para a extração e purificação do Fator de Desenvolvimento Placentário recombinante (PLGF) expresso em sistemas de expressão procarióticos passíveis de indução compreendendo as seguintes etapas: I) fermentação das células bacterianas, II) extração e purificação dos corpos de inclusão, III) renaturação da proteína expressa, IV) cromatografia de troca iónica, V) cromatografia de fase reversa.
BR0215585-0A 2002-02-05 2002-02-05 Processo de produção de fator de desenvolvimento placentário BR0215585A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2002/000065 WO2003066676A1 (en) 2002-02-05 2002-02-05 Production process of recombinant placental growth factor

Publications (1)

Publication Number Publication Date
BR0215585A true BR0215585A (pt) 2004-12-21

Family

ID=27676896

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215585-0A BR0215585A (pt) 2002-02-05 2002-02-05 Processo de produção de fator de desenvolvimento placentário

Country Status (23)

Country Link
US (1) US7744862B2 (pt)
EP (1) EP1472286B1 (pt)
JP (1) JP4458850B2 (pt)
KR (1) KR100869400B1 (pt)
CN (1) CN100588661C (pt)
AT (1) ATE358681T1 (pt)
AU (1) AU2002236197B2 (pt)
BR (1) BR0215585A (pt)
CA (1) CA2475235C (pt)
CY (1) CY1106681T1 (pt)
CZ (1) CZ2004892A3 (pt)
DE (1) DE60219361T2 (pt)
DK (1) DK1472286T3 (pt)
EE (1) EE05407B1 (pt)
ES (1) ES2284816T3 (pt)
HK (1) HK1076633A1 (pt)
HR (1) HRP20040795A2 (pt)
HU (1) HU229056B1 (pt)
MX (1) MXPA04007589A (pt)
PT (1) PT1472286E (pt)
SI (1) SI1472286T1 (pt)
SK (1) SK287965B6 (pt)
WO (1) WO2003066676A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
US8048003B2 (en) * 2003-10-14 2011-11-01 Suros Surgical Systems, Inc. Vacuum assisted biopsy device
US8921518B2 (en) 2005-12-23 2014-12-30 Novo Nordisk A/S Purification of proteins using preparative reverse phase chromatography (RPC)
CN101497883B (zh) * 2008-01-30 2013-02-27 苏州思坦维生物技术有限责任公司 重组胎盘生长因子的表达生产、分离纯化及其化学标记
US20090254411A1 (en) * 2008-04-04 2009-10-08 Kamal Bhattacharya System and method for automated decision support for service transition management
US8741287B2 (en) 2008-06-18 2014-06-03 Abbott Laboratories PlGF-1 assay and kits and components thereof
US20100004306A1 (en) * 2008-06-18 2010-01-07 Abbott Laboratories PIGF-1 Assay and kits and components thereof
EP2295449A1 (en) 2009-09-09 2011-03-16 Dompe PHA.R.MA S.p.A. PLGF-1 in homodimeric form
WO2014117155A1 (en) * 2013-01-28 2014-07-31 Shire Human Genetic Therapies, Inc. Placenta growth factor in treating duchenne muscular dystrophy
CN106589100B (zh) * 2016-12-14 2020-04-21 辽宁师范大学 可抗血管新生的七鳃鳗重组pr-1蛋白及制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1129478B (it) * 1980-12-23 1986-06-04 Olivetti & Co Spa Stampante termica seriale a punti
JPH0227993A (ja) * 1988-07-15 1990-01-30 Nippon Shinyaku Co Ltd ｈＥＧＦの製法
JPH03285677A (ja) * 1989-05-08 1991-12-16 Res Assoc Util Of Light Oil 形質転換された微生物の培養方法
GB8927008D0 (en) * 1989-11-29 1990-01-17 Ciba Geigy Novel process for the production of unfused protein in e.coli
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
IT1242149B (it) * 1990-09-27 1994-02-16 Consiglio Nazionale Ricerche Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
JP2002513283A (ja) * 1997-01-17 2002-05-08 ザ スクリップス リサーチ インスティテュート 組換え分子の発現に有用なｒｎａ結合タンパク質及び結合部位
US6221608B1 (en) * 1997-01-22 2001-04-24 Ortho Pharmaceutical Corporation Methods for identifying erythropoietin receptor binding protein
FR2766192B1 (fr) * 1997-07-17 2001-07-13 Pf Medicament Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie
DE19748734A1 (de) * 1997-11-05 1999-05-06 Biotechnolog Forschung Gmbh Verfahren zur Gewinnung von biologisch aktiven Dimeren von rekombinanten humanen Wachstumsfaktoren aus der Cystein-Knoten-Familie sowie Verwendung der gewonnenen Dimere
US6218181B1 (en) * 1998-03-18 2001-04-17 The Salk Institute For Biological Studies Retroviral packaging cell line
AU3959499A (en) * 1998-05-28 1999-12-13 Korea Green Cross Corporation Process of purifying angiogenesis inhibitors
JP5031967B2 (ja) * 2000-03-22 2012-09-26 イントレキソン コーポレーション 新規エクジソン受容体ベースの誘導性遺伝子発現系

Also Published As

Publication number Publication date
AU2002236197B2 (en) 2008-08-07
AU2002236197A1 (en) 2003-09-02
EP1472286B1 (en) 2007-04-04
HRP20040795A2 (en) 2004-12-31
DE60219361T2 (de) 2007-12-13
HK1076633A1 (en) 2006-01-20
JP2005535286A (ja) 2005-11-24
HUP0500029A2 (hu) 2005-03-29
US20050070696A1 (en) 2005-03-31
EE05407B1 (et) 2011-04-15
SK287965B6 (sk) 2012-07-03
ES2284816T3 (es) 2007-11-16
HU229056B1 (en) 2013-07-29
US7744862B2 (en) 2010-06-29
SI1472286T1 (sl) 2007-08-31
ATE358681T1 (de) 2007-04-15
EP1472286A1 (en) 2004-11-03
KR100869400B1 (ko) 2008-11-21
DK1472286T3 (da) 2007-08-20
CZ2004892A3 (cs) 2005-02-16
CA2475235C (en) 2013-04-30
SK3282004A3 (sk) 2005-01-03
CN100588661C (zh) 2010-02-10
EE200400108A (et) 2004-10-15
CN1620465A (zh) 2005-05-25
MXPA04007589A (es) 2005-06-08
PT1472286E (pt) 2007-06-28
WO2003066676A1 (en) 2003-08-14
KR20040091008A (ko) 2004-10-27
JP4458850B2 (ja) 2010-04-28
DE60219361D1 (de) 2007-05-16
CA2475235A1 (en) 2003-08-14
CY1106681T1 (el) 2012-05-23
HUP0500029A3 (en) 2010-01-28

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O C/C 11, 8O C/C 13, 10 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.