CY1106681T1 - Διεργασια παραγωγης του ανασυνδyασμενου πλακουντιου αυξητικου παραγοντα - Google Patents

Διεργασια παραγωγης του ανασυνδyασμενου πλακουντιου αυξητικου παραγοντα

Info

Publication number
CY1106681T1
CY1106681T1 CY20071100847T CY071100847T CY1106681T1 CY 1106681 T1 CY1106681 T1 CY 1106681T1 CY 20071100847 T CY20071100847 T CY 20071100847T CY 071100847 T CY071100847 T CY 071100847T CY 1106681 T1 CY1106681 T1 CY 1106681T1
Authority
CY
Cyprus
Prior art keywords
growth factor
placental growth
production process
factor production
recombinant placental
Prior art date
Application number
CY20071100847T
Other languages
English (en)
Inventor
Domenico Maglione
Mauro Battisti
Ettore Conti
Giuseppe Salvia
Marina Tucci
Original Assignee
Geymonat S.P.A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27676896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1106681(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geymonat S.P.A filed Critical Geymonat S.P.A
Publication of CY1106681T1 publication Critical patent/CY1106681T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Διεργασία για την εκχύλιση και τον καθαρισμό του ανασυνδυασμένου Πλακούντιου Αυξητικού Παράγοντα (PLGF) που εκφράζεται μέσα σε επαγώγιμα προκαρυωτικά συστήματα έκφρασης, περιλαμβάνοντας τα παρακάτω βήματα: Ι) ζύμωση των βακτηριδιακών κυττάρων, ΙΙ) εκχύλιση και καθαρισμός των σωμάτων εγκλεισμού, ΙΙΙ) επαναδιάταξη της εκπεφρασθείσας πρωτεΐνης, IV) ιοντοανταλλακτική χρωμογραφία V) χρωματογραφία αντίστροφης-φάσης.
CY20071100847T 2002-02-05 2007-06-26 Διεργασια παραγωγης του ανασυνδyασμενου πλακουντιου αυξητικου παραγοντα CY1106681T1 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2002/000065 WO2003066676A1 (en) 2002-02-05 2002-02-05 Production process of recombinant placental growth factor

Publications (1)

Publication Number Publication Date
CY1106681T1 true CY1106681T1 (el) 2012-05-23

Family

ID=27676896

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100847T CY1106681T1 (el) 2002-02-05 2007-06-26 Διεργασια παραγωγης του ανασυνδyασμενου πλακουντιου αυξητικου παραγοντα

Country Status (23)

Country Link
US (1) US7744862B2 (el)
EP (1) EP1472286B1 (el)
JP (1) JP4458850B2 (el)
KR (1) KR100869400B1 (el)
CN (1) CN100588661C (el)
AT (1) ATE358681T1 (el)
AU (1) AU2002236197B2 (el)
BR (1) BR0215585A (el)
CA (1) CA2475235C (el)
CY (1) CY1106681T1 (el)
CZ (1) CZ2004892A3 (el)
DE (1) DE60219361T2 (el)
DK (1) DK1472286T3 (el)
EE (1) EE05407B1 (el)
ES (1) ES2284816T3 (el)
HK (1) HK1076633A1 (el)
HR (1) HRP20040795A2 (el)
HU (1) HU229056B1 (el)
MX (1) MXPA04007589A (el)
PT (1) PT1472286E (el)
SI (1) SI1472286T1 (el)
SK (1) SK287965B6 (el)
WO (1) WO2003066676A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
US8048003B2 (en) * 2003-10-14 2011-11-01 Suros Surgical Systems, Inc. Vacuum assisted biopsy device
US8921518B2 (en) 2005-12-23 2014-12-30 Novo Nordisk A/S Purification of proteins using preparative reverse phase chromatography (RPC)
CN101497883B (zh) * 2008-01-30 2013-02-27 苏州思坦维生物技术有限责任公司 重组胎盘生长因子的表达生产、分离纯化及其化学标记
US20090254411A1 (en) * 2008-04-04 2009-10-08 Kamal Bhattacharya System and method for automated decision support for service transition management
US20100004306A1 (en) * 2008-06-18 2010-01-07 Abbott Laboratories PIGF-1 Assay and kits and components thereof
US8741287B2 (en) 2008-06-18 2014-06-03 Abbott Laboratories PlGF-1 assay and kits and components thereof
EP2295449A1 (en) 2009-09-09 2011-03-16 Dompe PHA.R.MA S.p.A. PLGF-1 in homodimeric form
US10729746B2 (en) 2013-01-28 2020-08-04 Shire Human Genetic Therapies, Inc. Recombinant placenta growth factor for treating Duchenne muscular dystrophy
CN106589100B (zh) * 2016-12-14 2020-04-21 辽宁师范大学 可抗血管新生的七鳃鳗重组pr-1蛋白及制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1129478B (it) * 1980-12-23 1986-06-04 Olivetti & Co Spa Stampante termica seriale a punti
JPH0227993A (ja) * 1988-07-15 1990-01-30 Nippon Shinyaku Co Ltd ｈＥＧＦの製法
JPH03285677A (ja) * 1989-05-08 1991-12-16 Res Assoc Util Of Light Oil 形質転換された微生物の培養方法
GB8927008D0 (en) * 1989-11-29 1990-01-17 Ciba Geigy Novel process for the production of unfused protein in e.coli
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
IT1242149B (it) * 1990-09-27 1994-02-16 Consiglio Nazionale Ricerche Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
JP2002513283A (ja) * 1997-01-17 2002-05-08 ザ スクリップス リサーチ インスティテュート 組換え分子の発現に有用なｒｎａ結合タンパク質及び結合部位
US6221608B1 (en) * 1997-01-22 2001-04-24 Ortho Pharmaceutical Corporation Methods for identifying erythropoietin receptor binding protein
FR2766192B1 (fr) * 1997-07-17 2001-07-13 Pf Medicament Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie
DE19748734A1 (de) * 1997-11-05 1999-05-06 Biotechnolog Forschung Gmbh Verfahren zur Gewinnung von biologisch aktiven Dimeren von rekombinanten humanen Wachstumsfaktoren aus der Cystein-Knoten-Familie sowie Verwendung der gewonnenen Dimere
US6218181B1 (en) * 1998-03-18 2001-04-17 The Salk Institute For Biological Studies Retroviral packaging cell line
WO1999061464A1 (en) * 1998-05-28 1999-12-02 Korea Green Cross Corporation Process of purifying angiogenesis inhibitors
CN1304578C (zh) * 2000-03-22 2007-03-14 罗姆和哈斯公司 新的基于蜕皮激素受体的可诱导的基因表达系统

Also Published As

Publication number Publication date
HU229056B1 (en) 2013-07-29
PT1472286E (pt) 2007-06-28
DE60219361D1 (de) 2007-05-16
SK287965B6 (sk) 2012-07-03
WO2003066676A1 (en) 2003-08-14
AU2002236197A1 (en) 2003-09-02
MXPA04007589A (es) 2005-06-08
KR20040091008A (ko) 2004-10-27
HRP20040795A2 (en) 2004-12-31
CN100588661C (zh) 2010-02-10
DK1472286T3 (da) 2007-08-20
US20050070696A1 (en) 2005-03-31
CA2475235A1 (en) 2003-08-14
ATE358681T1 (de) 2007-04-15
JP2005535286A (ja) 2005-11-24
EE200400108A (et) 2004-10-15
CZ2004892A3 (cs) 2005-02-16
SI1472286T1 (sl) 2007-08-31
BR0215585A (pt) 2004-12-21
KR100869400B1 (ko) 2008-11-21
EE05407B1 (et) 2011-04-15
EP1472286A1 (en) 2004-11-03
US7744862B2 (en) 2010-06-29
EP1472286B1 (en) 2007-04-04
CA2475235C (en) 2013-04-30
CN1620465A (zh) 2005-05-25
JP4458850B2 (ja) 2010-04-28
HK1076633A1 (en) 2006-01-20
AU2002236197B2 (en) 2008-08-07
ES2284816T3 (es) 2007-11-16
HUP0500029A2 (hu) 2005-03-29
HUP0500029A3 (en) 2010-01-28
DE60219361T2 (de) 2007-12-13
SK3282004A3 (sk) 2005-01-03

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