IL164677A0 - Isoquinoline derives - Google Patents

Isoquinoline derives

Info

Publication number
IL164677A0
IL164677A0 IL16467704A IL16467704A IL164677A0 IL 164677 A0 IL164677 A0 IL 164677A0 IL 16467704 A IL16467704 A IL 16467704A IL 16467704 A IL16467704 A IL 16467704A IL 164677 A0 IL164677 A0 IL 164677A0
Authority
IL
Israel
Prior art keywords
isoquinoline
derives
isoquinoline derives
Prior art date
Application number
IL16467704A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL164677A0 publication Critical patent/IL164677A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL16467704A 2002-04-26 2004-10-18 Isoquinoline derives IL164677A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02009253 2002-04-26
PCT/EP2003/003845 WO2003091219A1 (en) 2002-04-26 2003-04-14 Isoquinoline derivatives

Publications (1)

Publication Number Publication Date
IL164677A0 true IL164677A0 (en) 2005-12-18

Family

ID=29265896

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16467704A IL164677A0 (en) 2002-04-26 2004-10-18 Isoquinoline derives

Country Status (30)

Country Link
US (1) US6818774B2 (pl)
EP (1) EP1501804B1 (pl)
JP (1) JP4322685B2 (pl)
KR (1) KR100681585B1 (pl)
CN (1) CN1310890C (pl)
AR (1) AR039651A1 (pl)
AT (1) ATE440821T1 (pl)
AU (1) AU2003227614B2 (pl)
BR (1) BR0309562A (pl)
CA (1) CA2483461C (pl)
DE (1) DE60328978D1 (pl)
DK (1) DK1501804T3 (pl)
ES (1) ES2329354T3 (pl)
GT (1) GT200300095A (pl)
HR (1) HRP20040952A2 (pl)
IL (1) IL164677A0 (pl)
MX (1) MXPA04010537A (pl)
MY (1) MY133527A (pl)
NO (1) NO20044571L (pl)
NZ (1) NZ535885A (pl)
PA (1) PA8572001A1 (pl)
PE (1) PE20040594A1 (pl)
PL (1) PL373697A1 (pl)
PT (1) PT1501804E (pl)
RU (1) RU2318812C2 (pl)
SI (1) SI1501804T1 (pl)
TW (1) TWI278451B (pl)
UY (1) UY27786A1 (pl)
WO (1) WO2003091219A1 (pl)
ZA (1) ZA200408281B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150088A (en) 2003-05-19 2013-11-29 Irm Llc Immunosuppressant compounds and compositions
CN102174042B (zh) * 2003-05-19 2013-09-18 Irm有限责任公司 免疫抑制剂化合物和组合物
AU2004240649A1 (en) * 2003-05-19 2004-12-02 Irm, Llc Immunosuppressant compounds and compositions
AU2004268455B2 (en) * 2003-08-29 2009-12-17 Ono Pharmaceutical Co., Ltd. Compound capable of binding S1P receptor and pharmaceutical use thereof
US7825109B2 (en) 2003-08-29 2010-11-02 Ono Pharmaceutical Co., Ltd. Compound capable of binding S1P receptor and pharmaceutical use thereof
RU2006117366A (ru) * 2003-10-23 2007-12-10 Ф.Хоффманн-Ля Рош Аг (Ch) Производные бензазепина в качестве ингибиторов мао-в
RU2378257C2 (ru) 2004-03-01 2010-01-10 Актелион Фармасьютиклз Лтд Замещенные производные 1,2,3,4-тетрагидроизохинолина
CA2591399C (en) 2004-12-13 2014-05-20 Ono Pharmaceutical Co., Ltd. Aminocarboxylic acid derivative and medicinal use thereof
EP1844033B1 (de) * 2005-01-28 2011-07-27 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur herstellung von isochroman und derivaten davon
CA2598762A1 (en) 2005-02-25 2006-08-31 F. Hoffmann-La Roche Ag Tablets with improved drug substance dispersibility
IN266803B (pl) 2005-12-22 2015-06-03 Newron Pharm Spa
EA015256B1 (ru) * 2006-03-15 2011-06-30 Актелион Фармасьютикалз Лтд. Производные тетрагидроизохинолина для повышения функции памяти
DE602007012072D1 (de) 2006-04-26 2011-03-03 Actelion Pharmaceuticals Ltd Orantagonisten
KR101220182B1 (ko) 2009-02-25 2013-01-11 에스케이바이오팜 주식회사 치환된 아졸 유도체 화합물, 이를 포함하는 약제학적 조성물 및 이를 이용한 파킨슨씨 병 치료방법
CN105315204B (zh) * 2014-07-04 2018-02-09 中南大学 7‑氨基‑1,4‑二氢异喹啉‑3(2h)‑酮衍生物及其合成方法和用途
CN105461626B (zh) * 2015-12-17 2018-05-08 浙江工业大学 芳环或稠杂环联3,4-二氢异喹啉类共轭结构化合物及其应用
CN105585527B (zh) * 2015-12-17 2018-06-26 浙江工业大学 2-(3,4-二氢异喹啉-1(2h)-亚基)乙腈类化合物及其应用
JP7150745B2 (ja) * 2017-03-27 2022-10-11 ブリストル-マイヤーズ スクイブ カンパニー 免疫調節剤としての置換イソキノリン誘導体
US11992535B2 (en) * 2019-12-18 2024-05-28 Chdi Foundation, Inc. Compounds and probes for imaging huntingtin protein
CN114591238B (zh) * 2022-03-25 2022-11-15 邦恩泰(山东)生物医药科技集团股份有限公司 一种异喹啉类药物中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110172A (en) * 1993-07-22 2001-10-31 Lilly Co Eli Bicyclic compounds and pharmaceutical compositions containing them
US6448269B1 (en) * 1993-07-22 2002-09-10 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
US6137002A (en) * 1993-07-22 2000-10-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
CA2244253C (en) 1996-03-15 2002-11-12 Somerset Pharmaceuticals, Inc. Method for preventing and treating peripheral neuropathy by administering selegiline
WO2001034172A2 (en) 1999-11-05 2001-05-17 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
HK1080836A1 (en) 2006-05-04
PL373697A1 (pl) 2005-09-05
US6818774B2 (en) 2004-11-16
US20030225122A1 (en) 2003-12-04
DK1501804T3 (da) 2009-10-12
RU2318812C2 (ru) 2008-03-10
PA8572001A1 (es) 2003-12-10
ES2329354T3 (es) 2009-11-25
CA2483461C (en) 2010-12-21
ATE440821T1 (de) 2009-09-15
PT1501804E (pt) 2009-10-29
KR100681585B1 (ko) 2007-02-09
UY27786A1 (es) 2003-10-31
GT200300095A (es) 2004-01-15
PE20040594A1 (es) 2004-08-30
ZA200408281B (en) 2005-10-14
CA2483461A1 (en) 2003-11-06
MY133527A (en) 2007-11-30
CN1310890C (zh) 2007-04-18
TW200307670A (en) 2003-12-16
SI1501804T1 (sl) 2009-12-31
NZ535885A (en) 2007-05-31
RU2004134575A (ru) 2005-07-20
AR039651A1 (es) 2005-03-02
KR20040104628A (ko) 2004-12-10
TWI278451B (en) 2007-04-11
MXPA04010537A (es) 2005-01-25
EP1501804B1 (en) 2009-08-26
AU2003227614A1 (en) 2003-11-10
HRP20040952A2 (en) 2005-06-30
EP1501804A1 (en) 2005-02-02
WO2003091219A1 (en) 2003-11-06
JP2005533761A (ja) 2005-11-10
CN1649844A (zh) 2005-08-03
NO20044571L (no) 2004-10-22
DE60328978D1 (de) 2009-10-08
AU2003227614B2 (en) 2008-06-26
BR0309562A (pt) 2005-02-15
JP4322685B2 (ja) 2009-09-02

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees