IL159166A0 - Negatively charged amphiphilic block copolymer as drug carrier and complex thereof with positively charged drug - Google Patents

Negatively charged amphiphilic block copolymer as drug carrier and complex thereof with positively charged drug

Info

Publication number
IL159166A0
IL159166A0 IL15916602A IL15916602A IL159166A0 IL 159166 A0 IL159166 A0 IL 159166A0 IL 15916602 A IL15916602 A IL 15916602A IL 15916602 A IL15916602 A IL 15916602A IL 159166 A0 IL159166 A0 IL 159166A0
Authority
IL
Israel
Prior art keywords
drug
block copolymer
amphiphilic block
complex
positively charged
Prior art date
Application number
IL15916602A
Other languages
English (en)
Original Assignee
Samyang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samyang Corp filed Critical Samyang Corp
Publication of IL159166A0 publication Critical patent/IL159166A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C08G81/02—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B1/00—Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15916602A 2001-06-25 2002-06-05 Negatively charged amphiphilic block copolymer as drug carrier and complex thereof with positively charged drug IL159166A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020010036203A KR100566911B1 (ko) 2001-06-25 2001-06-25 약물 전달체용 음이온기-함유 양친성 블록 공중합체 및 그의 양이온성 약물과의 복합체
PCT/KR2002/001074 WO2003000778A1 (en) 2001-06-25 2002-06-05 Negatively charged amphiphilic block copolymer as drug carrier and complex thereof with positively charged drug

Publications (1)

Publication Number Publication Date
IL159166A0 true IL159166A0 (en) 2004-06-01

Family

ID=36792807

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15916602A IL159166A0 (en) 2001-06-25 2002-06-05 Negatively charged amphiphilic block copolymer as drug carrier and complex thereof with positively charged drug
IL159166A IL159166A (en) 2001-06-25 2003-12-03 Negatively charged amphiphilic copolymer block as a drug carrier and its complex with a positively charged drug

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL159166A IL159166A (en) 2001-06-25 2003-12-03 Negatively charged amphiphilic copolymer block as a drug carrier and its complex with a positively charged drug

Country Status (16)

Country Link
US (1) US6890560B2 (de)
EP (1) EP1399501B1 (de)
JP (1) JP4154328B2 (de)
KR (1) KR100566911B1 (de)
CN (1) CN1226332C (de)
AT (1) ATE337357T1 (de)
AU (1) AU2002303027C1 (de)
BR (1) BRPI0210335B8 (de)
CA (1) CA2449244C (de)
DE (1) DE60214173T2 (de)
ES (1) ES2269694T3 (de)
IL (2) IL159166A0 (de)
MX (1) MXPA03011619A (de)
NZ (1) NZ530176A (de)
WO (1) WO2003000778A1 (de)
ZA (1) ZA200309357B (de)

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US7763663B2 (en) * 2001-12-19 2010-07-27 University Of Massachusetts Polysaccharide-containing block copolymer particles and uses thereof
US7311901B2 (en) 2003-10-10 2007-12-25 Samyang Corporation Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery
JP2007509981A (ja) * 2003-10-31 2007-04-19 テバ ファーマシューティカル インダストリーズ リミティド 薬物デリバリー用ナノ粒子
ES2383300T3 (es) 2003-11-13 2012-06-20 Hanmi Holdings Co., Ltd Fragmento Fc de IgG para un vehículo de fármacos y procedimiento para su preparación
US7179867B2 (en) * 2003-11-26 2007-02-20 Industrial Technology Research Institute Thermosensitive biodegradable copolymer
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US20060260639A1 (en) * 2005-03-08 2006-11-23 Pejman Fani Method and system for processing substrates with sonic energy that reduces or eliminates damage to semiconductor devices
KR100773470B1 (ko) * 2005-04-25 2007-11-05 김태균 층간 소음 방지를 위한 방음판 구조
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
CA2645153A1 (en) 2006-03-09 2007-09-13 Coloplast A/S Degradable hydrophilic block copolymers with improved biocompatibility for soft tissue regeneration
SG179457A1 (en) 2006-12-01 2012-04-27 Anterios Inc Peptide nanoparticles and uses therefor
SG177184A1 (en) 2006-12-01 2012-01-30 Anterios Inc Amphiphilic entity nanoparticles
KR100918524B1 (ko) * 2007-02-14 2009-09-21 성균관대학교산학협력단 온도 및 피에치 민감성 블록공중합체 고분자 하이드로겔을이용한 주사가능한 약물전달체 및 약물전달방법
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
WO2009078756A1 (en) * 2007-12-19 2009-06-25 Ardenia Investments, Ltd. Drug delivery system for administration of a water soluble, cationic and amphiphilic pharmaceutically active substance
WO2009078755A1 (en) * 2007-12-19 2009-06-25 Ardenia Investments, Ltd. Drug delivery system for administration of a water soluble, cationic and amphiphilic pharmaceutically active substance
EP2285853B1 (de) * 2008-05-13 2013-02-27 University of Washington Micellenanordnungen
US8652506B2 (en) * 2008-06-05 2014-02-18 Boston Scientific Scimed, Inc. Bio-degradable block co-polymers for controlled release
KR101848095B1 (ko) * 2008-06-26 2018-04-11 안테리오스, 인코퍼레이티드 경피 운반
JP5866117B2 (ja) * 2009-04-06 2016-02-17 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 分子を送達するための方法および材料
KR101220162B1 (ko) * 2009-07-02 2013-01-14 한양대학교 산학협력단 아르기닌―기제 양친성 펩티드 마이셀
KR101249389B1 (ko) * 2010-10-28 2013-04-03 재단법인대구경북과학기술원 자극반응성 수화젤
KR101685646B1 (ko) * 2010-12-29 2016-12-13 한화케미칼 주식회사 홍합 접착단백질 모방을 통한 나노입자를 수계 매질에 분산시키는 생체적합성 분산 안정화제
KR101230598B1 (ko) 2011-02-28 2013-02-15 부산대학교 산학협력단 페하 응답성을 가지는 히스트딘이 공유결합된 덱스트란과 메톡시폴리에틸렌글리콜 블록공중합체
AU2014296278C1 (en) 2013-07-30 2023-02-02 Genevant Sciences Gmbh Block copolymers and their conjugates or complexes with oligonucleotides
EP3043810B1 (de) 2013-09-09 2019-10-23 CanImGuide Therapeutics AB Immunsystemmodulatoren
WO2016144650A1 (en) 2015-03-06 2016-09-15 Canimguide Therapeutics Ab Immune system modulators and compositions
CN105362251B (zh) * 2015-12-14 2019-02-26 四川大学 DOTAP-mPEG-PLA纳米粒及其纳米粒溶液、载药复合物和制备方法和应用
MX2019005833A (es) 2016-11-21 2019-10-30 Eirion Therapeutics Inc Administracion transdermica de agentes grandes.
EP3562510A4 (de) 2016-12-30 2021-01-06 Genevant Sciences GmbH Verzweigte peg-moleküle sowie zugehörige zusammensetzungen und verfahren
US12558308B2 (en) 2017-12-18 2026-02-24 C.R. Bard, Inc. Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents
US11590080B2 (en) 2017-12-18 2023-02-28 C.R. Bard, Inc. Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents
CN112004528B (zh) * 2017-12-18 2023-01-03 巴德股份有限公司 载药微珠组合物、栓塞组合物和相关方法
CN110742903B (zh) * 2019-11-22 2021-06-01 兰州大学 含铑(ⅰ)的聚合物胶束、其制备方法与应用
WO2023012357A1 (en) 2021-08-05 2023-02-09 Medincell Pharmaceutical composition
US12521347B2 (en) 2021-10-25 2026-01-13 The Secant Group, Llc Polymeric delivery systems

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Also Published As

Publication number Publication date
HK1067950A1 (en) 2005-04-22
ZA200309357B (en) 2005-05-25
CA2449244A1 (en) 2003-01-03
JP4154328B2 (ja) 2008-09-24
JP2004530768A (ja) 2004-10-07
BR0210335A (pt) 2004-07-20
MXPA03011619A (es) 2004-04-05
KR100566911B1 (ko) 2006-04-03
EP1399501B1 (de) 2006-08-23
EP1399501A4 (de) 2005-02-16
CN1520437A (zh) 2004-08-11
CA2449244C (en) 2007-10-02
EP1399501A1 (de) 2004-03-24
AU2002303027C1 (en) 2006-06-01
WO2003000778A1 (en) 2003-01-03
CN1226332C (zh) 2005-11-09
IL159166A (en) 2007-12-03
DE60214173T2 (de) 2007-08-23
KR20030000433A (ko) 2003-01-06
ES2269694T3 (es) 2007-04-01
AU2002303027B2 (en) 2005-06-09
US20030017206A1 (en) 2003-01-23
BRPI0210335B8 (pt) 2021-05-25
NZ530176A (en) 2005-06-24
DE60214173D1 (de) 2006-10-05
US6890560B2 (en) 2005-05-10
ATE337357T1 (de) 2006-09-15
BR0210335B1 (pt) 2014-06-24

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