IL156136A0 - Therapeutic combination of amlodipine and benazepril - Google Patents

Therapeutic combination of amlodipine and benazepril

Info

Publication number
IL156136A0
IL156136A0 IL15613600A IL15613600A IL156136A0 IL 156136 A0 IL156136 A0 IL 156136A0 IL 15613600 A IL15613600 A IL 15613600A IL 15613600 A IL15613600 A IL 15613600A IL 156136 A0 IL156136 A0 IL 156136A0
Authority
IL
Israel
Prior art keywords
amlodipine
pharmaceutically acceptable
benazepril
disease
corresponds
Prior art date
Application number
IL15613600A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21742073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL156136(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL156136A0 publication Critical patent/IL156136A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
IL15613600A 2000-12-18 2000-12-18 Therapeutic combination of amlodipine and benazepril IL156136A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/034246 WO2002049645A1 (en) 2000-12-18 2000-12-18 Therapeutic combination of amlodipine and benazepril

Publications (1)

Publication Number Publication Date
IL156136A0 true IL156136A0 (en) 2003-12-23

Family

ID=21742073

Family Applications (4)

Application Number Title Priority Date Filing Date
IL15613600A IL156136A0 (en) 2000-12-18 2000-12-18 Therapeutic combination of amlodipine and benazepril
IL15626701A IL156267A0 (en) 2000-12-18 2001-12-17 Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190802A IL190802A0 (en) 2000-12-18 2008-04-10 Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190801A IL190801A0 (en) 2000-12-18 2008-04-10 Therapeutic combination of amlodipine and benazepril/benazeprilat

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL15626701A IL156267A0 (en) 2000-12-18 2001-12-17 Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190802A IL190802A0 (en) 2000-12-18 2008-04-10 Therapeutic combination of amlodipine and benazepril/benazeprilat
IL190801A IL190801A0 (en) 2000-12-18 2008-04-10 Therapeutic combination of amlodipine and benazepril/benazeprilat

Country Status (26)

Country Link
EP (3) EP1365761A1 (es)
JP (3) JP2004516266A (es)
KR (3) KR20040007420A (es)
CN (2) CN1461218A (es)
AT (1) ATE338549T1 (es)
AU (4) AU2581601A (es)
BR (2) BR0017386A (es)
CA (2) CA2432638A1 (es)
CY (1) CY1106275T1 (es)
CZ (2) CZ20031678A3 (es)
DE (1) DE60122928T2 (es)
DK (1) DK1345607T3 (es)
EC (1) ECSP034658A (es)
ES (1) ES2272565T3 (es)
HU (2) HUP0302455A3 (es)
IL (4) IL156136A0 (es)
MX (2) MXPA03005462A (es)
NO (2) NO20032765L (es)
NZ (1) NZ526467A (es)
PL (2) PL362252A1 (es)
PT (1) PT1345607E (es)
RU (1) RU2292206C2 (es)
SI (1) SI1345607T1 (es)
SK (2) SK7652003A3 (es)
WO (2) WO2002049645A1 (es)
ZA (1) ZA200304514B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005511631A (ja) * 2001-11-23 2005-04-28 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング 脳血管障害発作の急性期における高血圧症の治療
US20040229901A1 (en) * 2003-02-24 2004-11-18 Lauren Otsuki Method of treatment of disease using an adenosine A1 receptor antagonist
MXPA05011371A (es) 2003-04-25 2005-12-01 Novacardia Inc Metodo para mejorar la diuresis en individuos con la funcion renal deteriorada.
CN101137367A (zh) * 2003-10-20 2008-03-05 诺瓦提斯公司 用于降低心血管发病率的贝那普利和氨氯地平
WO2005074927A1 (en) * 2004-02-09 2005-08-18 Novartis Ag Therapeutic combination of amlodipine and benazepril/ benazeprilat for the treatment of hypertension
WO2005079772A2 (en) * 2004-02-18 2005-09-01 Sepracor Inc. Combination of (s)-amlodipine and an ace inhibitor, and methods for reducing hypertension
DE102004011512B4 (de) 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmazeutische Zubereitung enthaltend Pimobendan
EP1579862A1 (en) * 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
US20080268049A1 (en) * 2005-02-11 2008-10-30 Dhaliwal Mona Stable Solid Dosage Forms of Amlodipine and Benazepril
WO2006092732A2 (en) * 2005-03-04 2006-09-08 Aurobindo Pharma Ltd Stable solid dosage form of antihypertensive agent
WO2006097943A2 (en) 2005-03-15 2006-09-21 Lupin Limited Pharmaceutical compositions of amlodipine and benazepril
CA2620018A1 (en) * 2005-09-28 2007-04-12 Mali Kadosh Stable combinations of amlodipine besylate and benazepril hydrochloride
US8158146B2 (en) 2005-09-28 2012-04-17 Teva Pharmaceutical Industries Ltd. Stable combinations of amlodipine besylate and benazepril hydrochloride
PT1797885E (pt) * 2005-09-28 2008-05-20 Teva Pharma Combinações estáveis de besilato de amlodipina e cloridrato de benazepril
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
IT1398168B1 (it) * 2010-02-16 2013-02-14 Chiesi Farma Spa Uso di ingredienti attivi in combinazione per il trattamento delle complicanze del diabete.
SI2585051T2 (sl) 2010-06-23 2020-07-31 Krka, D.D., Novo Mesto Farmacevtske oralne odmerne oblike,ki obsegajo lerkanidipin in enalapril in njune farmacevtsko sprejemljive soli
CN102389431A (zh) * 2011-09-28 2012-03-28 济南龙华医药技术有限公司 一种含有盐酸贝尼地平和盐酸贝那普利的复方制剂及其应用
ES2656412T3 (es) * 2011-12-21 2018-02-27 Elanco Tiergesundheit Ag Nueva combinación
HUE060093T2 (hu) 2012-03-15 2023-01-28 Boehringer Ingelheim Vetmedica Gmbh Gyógyszerészeti tablettakészítmény az állatgyógyászati ágazat számára, eljárás annak elõállítására és annak alkalmazása
US20150218103A1 (en) * 2012-08-25 2015-08-06 The Johns Hopkins University Gapdh cascade inhibitor compounds and methods of use and treatment of stress induced disorders including mental illness
PL3865120T3 (pl) 2013-07-19 2025-10-13 Boehringer Ingelheim Vetmedica Gmbh Konserwowane eteryfikowane pochodne cyklodekstyrny zawierające ciekłą wodną kompozycję farmaceutyczną
DK3106150T3 (da) 2013-12-04 2021-11-01 Boehringer Ingelheim Vetmedica Gmbh Forbedrede farmaceutiske sammensætninger af pimobendan
JP6934859B2 (ja) * 2016-03-24 2021-09-15 第一三共株式会社 腎疾患の治療のための医薬
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
EP3541807B1 (en) 2016-11-16 2021-09-29 H. Lundbeck A/S A crystalline form of a magl inhibitor
CN110290791A (zh) 2016-11-16 2019-09-27 灵北拉荷亚研究中心公司 药物制剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162802A (en) * 1992-03-10 2000-12-19 Papa; Joseph Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
ES2193233T3 (es) * 1995-03-16 2003-11-01 Pfizer Uso de amiodipina, una sal de la misma o felodipina en combinacion con un inhibidor ace en la fabricacion de un medicamento para el tratamiento de insuficiencia cardiaca conjuntiva no isquemica.
CZ313897A3 (cs) * 1995-04-07 1998-01-14 Novartis Ag Farmaceutické kompozice obsahující benazepril nebo benazeprilát a valsartan
EP0795327A1 (en) * 1996-03-13 1997-09-17 Pfizer Inc. Use of Amlodipine for the treatment and prophylaxis of congestive cardiac failure of non-ischaemic origin

Also Published As

Publication number Publication date
RU2003121019A (ru) 2005-01-20
SI1345607T1 (sl) 2007-02-28
HK1059566A1 (en) 2004-07-09
DK1345607T3 (da) 2006-12-27
JP2010043111A (ja) 2010-02-25
PL360989A1 (en) 2004-09-20
CA2432638A1 (en) 2002-06-27
DE60122928T2 (de) 2007-09-06
EP1345607A1 (en) 2003-09-24
NO20032765D0 (no) 2003-06-17
AU2581601A (en) 2002-07-01
NO20032766D0 (no) 2003-06-17
CN1461218A (zh) 2003-12-10
SK7652003A3 (en) 2003-12-02
NO20032765L (no) 2003-08-14
CA2432282A1 (en) 2002-06-27
JP2004516266A (ja) 2004-06-03
SK7642003A3 (en) 2003-11-04
EP1345607B1 (en) 2006-09-06
EP1365761A1 (en) 2003-12-03
JP2004519440A (ja) 2004-07-02
KR20030061840A (ko) 2003-07-22
HUP0302455A2 (hu) 2003-11-28
ECSP034658A (es) 2003-07-25
ZA200304514B (en) 2004-05-10
RU2292206C2 (ru) 2007-01-27
CZ301424B6 (cs) 2010-02-24
MXPA03005463A (es) 2003-09-25
CZ20031678A3 (cs) 2003-10-15
IL156267A0 (en) 2004-01-04
KR20040007420A (ko) 2004-01-24
PT1345607E (pt) 2007-01-31
HUP0302456A2 (hu) 2003-11-28
KR20090033914A (ko) 2009-04-06
HUP0302455A3 (en) 2005-05-30
AU3262002A (en) 2002-07-01
ATE338549T1 (de) 2006-09-15
EP1674099A1 (en) 2006-06-28
WO2002049646A1 (en) 2002-06-27
IL190801A0 (en) 2008-11-03
AU2002232620B9 (en) 2005-11-24
CY1106275T1 (el) 2011-10-12
CZ20031677A3 (cs) 2003-10-15
HUP0302456A3 (en) 2004-05-28
WO2002049645A1 (en) 2002-06-27
AU2002232620B2 (en) 2005-11-03
BR0116228A (pt) 2003-12-30
NZ526467A (en) 2005-04-29
IL190802A0 (en) 2008-11-03
BR0017386A (pt) 2004-01-13
AU2001225816B2 (en) 2005-10-13
CN1481241A (zh) 2004-03-10
PL362252A1 (en) 2004-10-18
NO20032766L (no) 2003-08-14
ES2272565T3 (es) 2007-05-01
MXPA03005462A (es) 2003-09-25
DE60122928D1 (de) 2006-10-19

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