IL153703A0 - 9-alpha-chloro-6-alpha-fluoro-17-alpha-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17-alpha by a cyclic acyl group - Google Patents

9-alpha-chloro-6-alpha-fluoro-17-alpha-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17-alpha by a cyclic acyl group

Info

Publication number
IL153703A0
IL153703A0 IL15370301A IL15370301A IL153703A0 IL 153703 A0 IL153703 A0 IL 153703A0 IL 15370301 A IL15370301 A IL 15370301A IL 15370301 A IL15370301 A IL 15370301A IL 153703 A0 IL153703 A0 IL 153703A0
Authority
IL
Israel
Prior art keywords
alpha
androst
dienes
methoxycarbonyl
esterified
Prior art date
Application number
IL15370301A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL153703A0 publication Critical patent/IL153703A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL15370301A 2000-06-28 2001-06-26 9-alpha-chloro-6-alpha-fluoro-17-alpha-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17-alpha by a cyclic acyl group IL153703A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0015876.6A GB0015876D0 (en) 2000-06-28 2000-06-28 Organic compounds
PCT/EP2001/007249 WO2002000679A2 (en) 2000-06-28 2001-06-26 9.alpha.-chloro-6.alpha.-fluoro-17.alpha.-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17.alpha. by a cyclic acyl group

Publications (1)

Publication Number Publication Date
IL153703A0 true IL153703A0 (en) 2003-07-06

Family

ID=9894607

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15370301A IL153703A0 (en) 2000-06-28 2001-06-26 9-alpha-chloro-6-alpha-fluoro-17-alpha-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17-alpha by a cyclic acyl group
IL153703A IL153703A (en) 2000-06-28 2002-12-26 9 - Alpha - Chloro - 6 - Alpha - Fluoro - 17 - Alpha - Hydroxy - 16 - Methyl - 17 - Beta - Methoxycarbonyl - Androst - 4,1 - Dianes that have been sterilized in position 17 - Alpha by a group of ring nobles

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL153703A IL153703A (en) 2000-06-28 2002-12-26 9 - Alpha - Chloro - 6 - Alpha - Fluoro - 17 - Alpha - Hydroxy - 16 - Methyl - 17 - Beta - Methoxycarbonyl - Androst - 4,1 - Dianes that have been sterilized in position 17 - Alpha by a group of ring nobles

Country Status (30)

Country Link
US (1) US6921757B2 (ru)
EP (1) EP1299409B1 (ru)
JP (1) JP4065399B2 (ru)
KR (1) KR100483865B1 (ru)
CN (1) CN1214038C (ru)
AR (1) AR030707A1 (ru)
AT (1) ATE292639T1 (ru)
AU (2) AU8389101A (ru)
BR (1) BR0112068A (ru)
CA (1) CA2412541C (ru)
CZ (1) CZ302513B6 (ru)
DE (1) DE60109931T2 (ru)
EC (1) ECSP014101A (ru)
ES (1) ES2240499T3 (ru)
GB (1) GB0015876D0 (ru)
HK (1) HK1055974A1 (ru)
HU (1) HUP0300783A3 (ru)
IL (2) IL153703A0 (ru)
MX (1) MXPA02012830A (ru)
MY (1) MY129523A (ru)
NO (1) NO324055B1 (ru)
NZ (1) NZ523194A (ru)
PE (1) PE20020179A1 (ru)
PL (1) PL207722B1 (ru)
PT (1) PT1299409E (ru)
RU (1) RU2277100C2 (ru)
SK (1) SK286690B6 (ru)
TW (1) TWI232868B (ru)
WO (1) WO2002000679A2 (ru)
ZA (1) ZA200300202B (ru)

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MY129523A (en) 2007-04-30
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JP2004501930A (ja) 2004-01-22
HK1055974A1 (en) 2004-01-30
PT1299409E (pt) 2005-08-31
WO2002000679A3 (en) 2002-03-28
HUP0300783A3 (en) 2010-01-28
KR20030028768A (ko) 2003-04-10
EP1299409A2 (en) 2003-04-09
ZA200300202B (en) 2003-12-31
DE60109931D1 (de) 2005-05-12
IL153703A (en) 2007-05-15
MXPA02012830A (es) 2003-05-14
CZ302513B6 (cs) 2011-06-29
CZ20024203A3 (cs) 2003-04-16
TWI232868B (en) 2005-05-21
RU2277100C2 (ru) 2006-05-27
CN1214038C (zh) 2005-08-10
HUP0300783A2 (hu) 2003-07-28
US20030158163A1 (en) 2003-08-21
PL207722B1 (pl) 2011-01-31
AR030707A1 (es) 2003-09-03
NO20026253D0 (no) 2002-12-27
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ES2240499T3 (es) 2005-10-16
EP1299409B1 (en) 2005-04-06
CN1439018A (zh) 2003-08-27
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US6921757B2 (en) 2005-07-26
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