IL147683A0 - Microarrays and their manufacture - Google Patents
Microarrays and their manufactureInfo
- Publication number
- IL147683A0 IL147683A0 IL14768300A IL14768300A IL147683A0 IL 147683 A0 IL147683 A0 IL 147683A0 IL 14768300 A IL14768300 A IL 14768300A IL 14768300 A IL14768300 A IL 14768300A IL 147683 A0 IL147683 A0 IL 147683A0
- Authority
- IL
- Israel
- Prior art keywords
- microarrays
- manufacture
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50857—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00513—Essentially linear supports
- B01J2219/00515—Essentially linear supports in the shape of strings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00513—Essentially linear supports
- B01J2219/0052—Essentially linear supports in the shape of elongated tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00513—Essentially linear supports
- B01J2219/00524—Essentially linear supports in the shape of fiber bundles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00617—Delimitation of the attachment areas by chemical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00617—Delimitation of the attachment areas by chemical means
- B01J2219/00619—Delimitation of the attachment areas by chemical means using hydrophilic or hydrophobic regions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
- B01J2219/00644—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being present in discrete locations, e.g. gel pads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00664—Three-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00673—Slice arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00731—Saccharides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/12—Libraries containing saccharides or polysaccharides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/809—Multifield plates or multicontainer arrays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
- Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Clinical Laboratory Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14665399P | 1999-07-30 | 1999-07-30 | |
US09/482,460 US6713309B1 (en) | 1999-07-30 | 2000-01-13 | Microarrays and their manufacture |
PCT/US2000/020695 WO2001009607A1 (en) | 1999-07-30 | 2000-07-28 | Microarrays and their manufacture |
Publications (1)
Publication Number | Publication Date |
---|---|
IL147683A0 true IL147683A0 (en) | 2002-08-14 |
Family
ID=26844141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14768300A IL147683A0 (en) | 1999-07-30 | 2000-07-28 | Microarrays and their manufacture |
Country Status (9)
Country | Link |
---|---|
US (3) | US6713309B1 (ja) |
EP (1) | EP1204867A4 (ja) |
JP (16) | JP2003527569A (ja) |
KR (1) | KR20020042632A (ja) |
AU (1) | AU6750200A (ja) |
CA (1) | CA2376489A1 (ja) |
IL (1) | IL147683A0 (ja) |
MX (1) | MXPA02000992A (ja) |
WO (1) | WO2001009607A1 (ja) |
Families Citing this family (168)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6794127B1 (en) * | 1997-06-16 | 2004-09-21 | Diversa Corporation | Capillary array-based sample screening |
US6251691B1 (en) | 1996-04-25 | 2001-06-26 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
US6893877B2 (en) | 1998-01-12 | 2005-05-17 | Massachusetts Institute Of Technology | Methods for screening substances in a microwell array |
ATE322341T1 (de) * | 1998-01-12 | 2006-04-15 | Massachusetts Inst Technology | Verfahren und vorrichtung zur mikrotestdurchführung |
US7132247B1 (en) * | 1998-09-17 | 2006-11-07 | Regents Of The University Of Minnesota | Composite devices incorporating biological material and methods |
KR100538502B1 (ko) * | 1999-03-05 | 2005-12-23 | 미쯔비시 레이온 가부시끼가이샤 | 생체 관련 물질 함유 담체 |
NZ513390A (en) * | 1999-03-19 | 2003-01-31 | Genencor Int | Multi-through hole testing plate for high throughput screening |
US6824987B1 (en) * | 1999-05-11 | 2004-11-30 | President And Fellows Of Harvard College | Small molecule printing |
US6713309B1 (en) * | 1999-07-30 | 2004-03-30 | Large Scale Proteomics Corporation | Microarrays and their manufacture |
US6406840B1 (en) | 1999-12-17 | 2002-06-18 | Biomosaic Systems, Inc. | Cell arrays and the uses thereof |
US20020151040A1 (en) | 2000-02-18 | 2002-10-17 | Matthew O' Keefe | Apparatus and methods for parallel processing of microvolume liquid reactions |
US20010055765A1 (en) | 2000-02-18 | 2001-12-27 | O'keefe Matthew | Apparatus and methods for parallel processing of micro-volume liquid reactions |
US20010031495A1 (en) * | 2000-03-13 | 2001-10-18 | Hideji Tajima | Integrated support, integrated minute vessels and permeable membrane and method of making and using same |
DE10023505A1 (de) * | 2000-05-13 | 2001-11-22 | Fraunhofer Ges Forschung | Reaktormodul mit Kapillarmembranen |
KR100626244B1 (ko) * | 2000-06-20 | 2006-09-20 | 미츠비시 레이온 가부시키가이샤 | 생체 관련 물질 마이크로어레이 및 그의 제조 방법 |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
WO2001098765A1 (en) | 2000-06-21 | 2001-12-27 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis |
GB0024276D0 (en) * | 2000-10-04 | 2000-11-15 | Univ Cranfield | Substrate specific materials |
US20020051995A1 (en) * | 2000-10-30 | 2002-05-02 | Rajan Kumar | Stacked arrays |
DE60111906D1 (de) * | 2000-11-07 | 2005-08-18 | Advanced Gene Technology Corp | Verfahren zum Screenen von Pflanzenextrakten nach Wirkstoffen |
DE10110511C1 (de) * | 2001-02-28 | 2002-10-10 | Attomol Gmbh Molekulare Diagno | Verfahren zur Herstellung eines Arrays zur Detektion von Komponenten aus einer biologischen Probe |
US20020129889A1 (en) * | 2001-03-15 | 2002-09-19 | Anderson Norman G. | Method and apparatus for making fibers for sectioned arrays |
JP3937742B2 (ja) * | 2001-03-28 | 2007-06-27 | キヤノン株式会社 | プローブ担体及びその製造方法 |
DE10117135A1 (de) * | 2001-04-05 | 2002-10-17 | Biotechnolog Forschung Gmbh | Verfahren zur Herstellung einer Vielzahl identischer Kopien einer planaren Testanordnung von Sondenmolekülen |
DE10117275B4 (de) * | 2001-04-06 | 2005-02-24 | Hte Ag The High Throughput Experimentation Company | Vorrichtung zur Archivierung und Analyse von Materialien |
US6872320B2 (en) * | 2001-04-19 | 2005-03-29 | Xerox Corporation | Method for printing etch masks using phase-change materials |
US20040171068A1 (en) * | 2001-04-19 | 2004-09-02 | Juergen Wehland | Method for producing stable, regeneratable antibody arrays |
US6742884B2 (en) | 2001-04-19 | 2004-06-01 | Xerox Corporation | Apparatus for printing etch masks using phase-change materials |
DE10122836A1 (de) * | 2001-05-11 | 2002-11-28 | November Ag Molekulare Medizin | Faser, Faden und Verfahren zur Markierung und Identifizierung |
KR100917731B1 (ko) | 2001-05-11 | 2009-09-15 | 파나소닉 주식회사 | 생체분자 기판 및 그것을 이용한 검사 및 진단의 방법 및장치 |
US7262063B2 (en) * | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
JP2003014746A (ja) * | 2001-06-27 | 2003-01-15 | Fuji Photo Film Co Ltd | 生物学的素材が固定された構造体及びその製造方法 |
EP1281966A3 (en) * | 2001-07-30 | 2003-06-18 | Fuji Photo Film Co., Ltd. | Method and apparatus for conducting a receptor-ligand reaction |
WO2003027673A1 (fr) * | 2001-07-31 | 2003-04-03 | Olympus Corporation | Appareil d'inspection genique et procede d'extraction d'acide nucleique cible faisant appel a cet appareil |
US20030108917A1 (en) | 2001-09-01 | 2003-06-12 | Nam Huh | Method for manufacturing hydrogel biochip by using star-like polyethylene glycol derivative having epoxy group |
JPWO2003031952A1 (ja) * | 2001-09-28 | 2005-01-27 | 株式会社日立製作所 | 発光検出装置、発光検出用マイクロアレイプレート |
GB0124338D0 (en) | 2001-10-10 | 2001-11-28 | Randox Lab Ltd | Biochips |
US7085404B2 (en) * | 2001-10-11 | 2006-08-01 | Industry-University Cooperation Foundation, Hangyang University | Image analysis system and method of biochip |
WO2003034029A2 (en) | 2001-10-15 | 2003-04-24 | Bioarray Solutions, Ltd. | Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection |
US6797393B2 (en) * | 2001-11-30 | 2004-09-28 | Eastman Kodak Company | Method for making biochip substrate |
EP1462454A4 (en) * | 2001-12-11 | 2007-05-23 | Mitsubishi Rayon Co | NETWORK FOR CRYSTALLIZING PROTEINS, DEVICE FOR CRYSTALLIZING PROTEINS, AND METHOD FOR SCREENING PROTEIN CRYSTALLIZATION USING THE SAME |
US7335153B2 (en) * | 2001-12-28 | 2008-02-26 | Bio Array Solutions Ltd. | Arrays of microparticles and methods of preparation thereof |
WO2003062824A1 (en) * | 2002-01-23 | 2003-07-31 | Boditech Inc. | Lateral flow quantitative assay method and strip and laser-induced fluoerescence detection device therefor |
EP1333281A3 (en) * | 2002-01-31 | 2004-01-14 | Fuji Photo Film Co., Ltd. | Method and reactor for conducting receptor-ligand association reactions |
JP3933058B2 (ja) * | 2002-02-25 | 2007-06-20 | 日立化成工業株式会社 | マイクロ流体システム用支持ユニット及びその製造方法 |
US20040009584A1 (en) * | 2002-03-13 | 2004-01-15 | Rahul Mitra | Method for manufacturing microarrays based on the immobilization of porous substrates on thermally modifiable surfaces |
US20040052412A1 (en) * | 2002-05-10 | 2004-03-18 | Large Scale Biology Corporation | Satellite image enhancement and feature identification using information theory radial-basis bio-marker filter |
JP2003337117A (ja) * | 2002-05-17 | 2003-11-28 | Hitachi High-Technologies Corp | キャピラリアレイ及びキャピラリアレイの生産方法 |
US7011971B2 (en) * | 2002-06-03 | 2006-03-14 | Eastman Kodak Company | Method of making random array of microspheres using enzyme digestion |
US8277753B2 (en) * | 2002-08-23 | 2012-10-02 | Life Technologies Corporation | Microfluidic transfer pin |
JP2005537486A (ja) * | 2002-09-03 | 2005-12-08 | ツェプトゼンス アクチエンゲゼルシャフト | 分析対象物が試料中で固定化された特異的結合パートナーとして測定される分析プラットフォーム及び検出法 |
US7364896B2 (en) * | 2002-10-31 | 2008-04-29 | Agilent Technologies, Inc. | Test strips including flexible array substrates and method of hybridization |
US7526114B2 (en) | 2002-11-15 | 2009-04-28 | Bioarray Solutions Ltd. | Analysis, secure access to, and transmission of array images |
US20060094108A1 (en) * | 2002-12-20 | 2006-05-04 | Karl Yoder | Thermal cycler for microfluidic array assays |
US7682565B2 (en) * | 2002-12-20 | 2010-03-23 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
GB0304515D0 (en) * | 2003-02-27 | 2003-04-02 | Dakocytomation Denmark As | Standard |
DE10316689A1 (de) * | 2003-04-10 | 2004-10-28 | Dimitrij Dr. Plachov | Dreidimensionaler Chip |
EP1627839A4 (en) * | 2003-05-19 | 2009-11-11 | Mitsubishi Rayon Co | WIRE ARRANGEMENT DEVICE AND WIRE ARRANGEMENT METHOD THEREFOR, WIRE ARRANGEMENT INSTRUMENT, WIRE ARRANGEMENT BODY MANUFACTURING METHOD, AND MICRO-NETWORK FABRICATION METHOD IMMOBILIZING SUBSTANCE CONNECTED WITH LIVING ORGANISM |
US7556660B2 (en) | 2003-06-11 | 2009-07-07 | James Kevin Shurtleff | Apparatus and system for promoting a substantially complete reaction of an anhydrous hydride reactant |
GB0315991D0 (en) * | 2003-07-08 | 2003-08-13 | Dakocytomation Denmark As | Standard |
WO2005014805A1 (en) * | 2003-08-08 | 2005-02-17 | Regents Of The University Of Minnesota | A structured material for the production of hydrogen |
US7280727B1 (en) * | 2003-09-05 | 2007-10-09 | Schott Corporation | Micro-well and methods of fabricating and selectively blackening the same |
US20090052850A1 (en) * | 2003-09-05 | 2009-02-26 | Loic Barbedette | Micro-well plates and methods of fabricating and selectively blackening the same |
US7927796B2 (en) | 2003-09-18 | 2011-04-19 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
ES2375962T3 (es) | 2003-09-22 | 2012-03-07 | Bioarray Solutions Ltd | Polielectrolito inmovilizado en superficie con múltiples grupos funcionales capaces de unirse covalentemente a biomoléculas. |
AU2004286252A1 (en) | 2003-10-28 | 2005-05-12 | Bioarray Solutions Ltd. | Optimization of gene expression analysis using immobilized capture probes |
WO2005045060A2 (en) | 2003-10-29 | 2005-05-19 | Bioarray Solutions, Ltd. | Multiplexed nucleic acid analysis by fragmentation of double-stranded dna |
JPWO2005064334A1 (ja) * | 2003-12-30 | 2007-12-20 | ユニバーサル・バイオ・リサーチ株式会社 | 粒子三次元配列体を利用した反応容器及び反応装置 |
ATE448018T1 (de) * | 2004-02-18 | 2009-11-15 | Hitachi Chemical Co Ltd | Mikrofluidische einheit mit hohlfaser-kanal |
WO2005080570A1 (ja) | 2004-02-24 | 2005-09-01 | Mitsubishi Rayon Co., Ltd. | 乳癌の術後予後予測に関与する遺伝子 |
JP2007529015A (ja) | 2004-03-12 | 2007-10-18 | バイオトローブ, インコーポレイテッド | ナノリットルのアレイローディング |
RU2252411C1 (ru) * | 2004-04-09 | 2005-05-20 | Общество с ограниченной ответственностью "Институт рентгеновской оптики" | Флюоресцентный сенсор на основе многоканальных структур |
EP1758981A4 (en) | 2004-05-28 | 2013-01-16 | Wafergen Inc | APPARATUS AND METHODS FOR PERFORMING MULTIPLEX ANALYZES |
US20090054255A1 (en) | 2004-07-01 | 2009-02-26 | The Regents Of The University Of California | Microfluidic devices and methods |
US20070045777A1 (en) * | 2004-07-08 | 2007-03-01 | Jennifer Gillies | Micronized semiconductor nanocrystal complexes and methods of making and using same |
US7697808B2 (en) * | 2004-07-27 | 2010-04-13 | Ut-Battelle, Llc | Multi-tipped optical component |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
US20060105453A1 (en) | 2004-09-09 | 2006-05-18 | Brenan Colin J | Coating process for microfluidic sample arrays |
US7595157B2 (en) * | 2004-08-19 | 2009-09-29 | Biocept, Inc. | Microarrays utilizing hydrogels |
CN100348324C (zh) * | 2004-11-10 | 2007-11-14 | 厦门大学 | 阵列微量多通道移液器 |
JP4006002B2 (ja) * | 2004-11-26 | 2007-11-14 | キヤノン株式会社 | Dna担持繊維及びdna担持繊維シート並びにこれらの製造方法 |
EP1832861B1 (en) * | 2004-11-30 | 2020-04-29 | Hitachi Chemical Company, Ltd. | Analytical pretreatment device |
JPWO2006062191A1 (ja) * | 2004-12-09 | 2008-06-12 | 日立化成工業株式会社 | マイクロ流体システム用支持ユニット及びその製造方法 |
US20060194215A1 (en) * | 2005-02-28 | 2006-08-31 | Kronick Mel N | Methods, reagents and kits for reusing arrays |
US7189522B2 (en) | 2005-03-11 | 2007-03-13 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
WO2006098804A2 (en) * | 2005-03-11 | 2006-09-21 | Chembio Diagnostic Systems, Inc. | Dual path immunoassay device |
US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
AU2006273702A1 (en) * | 2005-07-28 | 2007-02-01 | Biosystems International Sas | Normalization of complex analyte mixtures |
US9012207B2 (en) * | 2005-08-02 | 2015-04-21 | University Of Utah Research Foundation | Biosensors including metallic nanocavities |
US20080020260A1 (en) * | 2005-11-12 | 2008-01-24 | Brydon Chris A | Apparatus, system, and method for manifolded integration of a humidification chamber for input gas for a proton exchange membrane fuel cell |
US20070148677A1 (en) * | 2005-12-02 | 2007-06-28 | Chagovetz Alexander M | Methods and systems for acquiring real-time quantitative melt data |
US20070134814A1 (en) * | 2005-12-09 | 2007-06-14 | Kajander E O | Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease |
AU2007277445A1 (en) * | 2006-01-03 | 2008-01-31 | Dana-Farber Cancer Institute | Small molecule printing |
US7657070B2 (en) * | 2006-01-20 | 2010-02-02 | Sakura Finetek U.S.A., Inc. | Automated system of processing biological specimens and method |
US8460878B2 (en) | 2006-02-21 | 2013-06-11 | The Trustees Of Tufts College | Methods and arrays for detecting cells and cellular components in small defined volumes |
US11237171B2 (en) | 2006-02-21 | 2022-02-01 | Trustees Of Tufts College | Methods and arrays for target analyte detection and determination of target analyte concentration in solution |
MX2008014037A (es) * | 2006-05-10 | 2009-03-26 | Armark Authentication Technolo | Filamento extruido que tiene indicio / codificacion de seccion transversal de alta definicion, sistema de etiquetado microscopico formado del mismo, y metodo de uso del mismo para contra - falsificacion y autenticacion de producto. |
US7651542B2 (en) | 2006-07-27 | 2010-01-26 | Thulite, Inc | System for generating hydrogen from a chemical hydride |
US7648786B2 (en) | 2006-07-27 | 2010-01-19 | Trulite, Inc | System for generating electricity from a chemical hydride |
CN101578520B (zh) | 2006-10-18 | 2015-09-16 | 哈佛学院院长等 | 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法 |
US8252581B2 (en) | 2007-01-22 | 2012-08-28 | Wafergen, Inc. | Apparatus for high throughput chemical reactions |
US20080243865A1 (en) * | 2007-03-28 | 2008-10-02 | Oracle International Corporation | Maintaining global state of distributed transaction managed by an external transaction manager for clustered database systems |
US8357214B2 (en) | 2007-04-26 | 2013-01-22 | Trulite, Inc. | Apparatus, system, and method for generating a gas from solid reactant pouches |
AU2008279082A1 (en) | 2007-07-25 | 2009-01-29 | Trulite, Inc. | Apparatus, system, and method to manage the generation and use of hybrid electric power |
US20090025293A1 (en) * | 2007-07-25 | 2009-01-29 | John Patton | Apparatus, system, and method for processing hydrogen gas |
JP5503540B2 (ja) | 2007-08-30 | 2014-05-28 | トラスティーズ・オブ・タフツ・カレッジ | 溶液中の分析物濃度を決定する方法 |
US8340913B2 (en) * | 2008-03-03 | 2012-12-25 | Schlumberger Technology Corporation | Phase behavior analysis using a microfluidic platform |
US8735846B1 (en) | 2008-03-14 | 2014-05-27 | Advanced Technology Applications, Llc | Electromagnetic biosensor |
US7812318B1 (en) | 2008-03-14 | 2010-10-12 | Advanced Technology Applications, Llc | Electromagnetic biosensor |
EP2265958A4 (en) * | 2008-03-27 | 2016-10-19 | Harvard College | MICROFLUIDIC SYSTEMS BASED ON PAPER |
EP2257818B1 (en) * | 2008-03-27 | 2017-05-10 | President and Fellows of Harvard College | Cotton thread as a low-cost multi-assay diagnostic platform |
CA2719320A1 (en) | 2008-03-27 | 2009-10-01 | President And Fellows Of Harvard College | Three-dimensional microfluidic devices |
CN103203210A (zh) * | 2008-03-27 | 2013-07-17 | 哈佛学院院长等 | 基于纸的细胞阵列 |
US9518288B2 (en) | 2008-04-11 | 2016-12-13 | University Of Utah Research Foundation | Methods and compositions related to quantitative, array based methylation analysis |
US20100022916A1 (en) | 2008-07-24 | 2010-01-28 | Javanbakhsh Esfandiari | Method and Apparatus for Collecting and Preparing Biological Samples for Testing |
US8715590B2 (en) * | 2008-08-15 | 2014-05-06 | Prognosys LLC | Multiplexed lateral flow assay arrays |
US20100075862A1 (en) * | 2008-09-23 | 2010-03-25 | Quanterix Corporation | High sensitivity determination of the concentration of analyte molecules or particles in a fluid sample |
US20100075439A1 (en) * | 2008-09-23 | 2010-03-25 | Quanterix Corporation | Ultra-sensitive detection of molecules by capture-and-release using reducing agents followed by quantification |
US8222047B2 (en) * | 2008-09-23 | 2012-07-17 | Quanterix Corporation | Ultra-sensitive detection of molecules on single molecule arrays |
ES2652615T3 (es) | 2009-01-22 | 2018-02-05 | Biopath Automation, L.L.C. | Soporte de biopsia seccionable de micrótomo para orientar muestras de tejido |
ES2612507T3 (es) | 2009-03-06 | 2017-05-17 | President And Fellows Of Harvard College | Dispositivos microfluídicos y electroquímicos |
WO2011015359A1 (en) * | 2009-08-05 | 2011-02-10 | Eth Zurich | Bioanalytical device |
JP2012231678A (ja) * | 2009-09-11 | 2012-11-29 | Espinex:Kk | 微生物検出方法 |
CA2788113A1 (en) | 2010-02-03 | 2011-08-11 | President And Fellows Of Harvard College | Devices and methods for multiplexed assays |
DE102010001714A1 (de) * | 2010-02-09 | 2011-08-11 | Robert Bosch GmbH, 70469 | Vorrichtung und Verfahren zur optischen Parallelanalyse einer Probenanordnung und entsprechendes Herstellungsverfahren |
US8236574B2 (en) | 2010-03-01 | 2012-08-07 | Quanterix Corporation | Ultra-sensitive detection of molecules or particles using beads or other capture objects |
US8415171B2 (en) | 2010-03-01 | 2013-04-09 | Quanterix Corporation | Methods and systems for extending dynamic range in assays for the detection of molecules or particles |
ES2544635T3 (es) | 2010-03-01 | 2015-09-02 | Quanterix Corporation | Métodos para extender el rango dinámico en ensayos para la detección de moléculas o partículas |
US9678068B2 (en) * | 2010-03-01 | 2017-06-13 | Quanterix Corporation | Ultra-sensitive detection of molecules using dual detection methods |
KR101273453B1 (ko) * | 2010-05-20 | 2013-06-11 | 고려대학교 산학협력단 | 효소가 집적된 미세튜브를 이용한 정량분석법 |
US9952237B2 (en) | 2011-01-28 | 2018-04-24 | Quanterix Corporation | Systems, devices, and methods for ultra-sensitive detection of molecules or particles |
US8603835B2 (en) | 2011-02-10 | 2013-12-10 | Chembio Diagnostic Systems, Inc. | Reduced step dual path immunoassay device and method |
JP5609700B2 (ja) * | 2011-02-17 | 2014-10-22 | ソニー株式会社 | 電気泳動素子および表示装置 |
JP5660468B2 (ja) * | 2011-03-15 | 2015-01-28 | 三菱レイヨン株式会社 | 生体関連物質検出用ゲルマイクロアレイの製造方法 |
JP2012198417A (ja) * | 2011-03-22 | 2012-10-18 | Sony Corp | 電気泳動素子、表示装置および電子機器 |
JP5673269B2 (ja) * | 2011-03-22 | 2015-02-18 | ソニー株式会社 | 電気泳動素子、表示装置および電子機器 |
JP5741122B2 (ja) * | 2011-03-28 | 2015-07-01 | ソニー株式会社 | 電気泳動素子、表示装置および電子機器 |
WO2012142301A2 (en) | 2011-04-12 | 2012-10-18 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury |
US20120275753A1 (en) * | 2011-04-28 | 2012-11-01 | Reinhardt Sherrh C | Fiber assembly with tray feature |
US9599623B2 (en) * | 2011-06-09 | 2017-03-21 | Immucor Gti Diagnostics, Inc. | Diagnostic devices, methods and systems for detecting platelet factor 4 (PF4)/heparin antibodies |
JP2013045074A (ja) * | 2011-08-26 | 2013-03-04 | Sony Corp | 電気泳動素子およびその製造方法、表示装置、表示基板ならびに電子機器 |
US20130078616A1 (en) * | 2011-09-16 | 2013-03-28 | The Governors Of The University Of Alberta | Method and system for amplification of nucleic acids in microfluidic volume hydrogels |
JP5870605B2 (ja) * | 2011-10-13 | 2016-03-01 | ソニー株式会社 | 表示装置およびその駆動方法、ならびに電子機器 |
JP5942394B2 (ja) * | 2011-11-22 | 2016-06-29 | ソニー株式会社 | 電気泳動素子および表示装置 |
CN103135309B (zh) * | 2011-11-22 | 2017-11-17 | 索尼公司 | 电泳装置、电泳装置的制造方法、以及显示器 |
CN103975053A (zh) * | 2011-12-01 | 2014-08-06 | 三菱丽阳株式会社 | 核酸扩增用基材以及核酸扩增方法 |
JP5953128B2 (ja) * | 2012-06-01 | 2016-07-20 | 秀明 久本 | アッセイ用キャピラリアレイの製造方法 |
JP5884659B2 (ja) * | 2012-06-29 | 2016-03-15 | ソニー株式会社 | 電気泳動素子および表示装置 |
TWI622845B (zh) * | 2012-09-05 | 2018-05-01 | Sony Corp | Electrophoresis element, display device and electronic device |
JP2014106333A (ja) * | 2012-11-27 | 2014-06-09 | Sony Corp | 電気泳動素子、表示装置および電子機器 |
US9932626B2 (en) | 2013-01-15 | 2018-04-03 | Quanterix Corporation | Detection of DNA or RNA using single molecule arrays and other techniques |
CN108663344A (zh) | 2013-02-19 | 2018-10-16 | 艾博特健康公司 | 分析生物流体样品的方法 |
JP6230091B2 (ja) * | 2013-03-13 | 2017-11-15 | 国立研究開発法人産業技術総合研究所 | マイクロアレイ、その製造方法、及びその用途 |
US9828284B2 (en) | 2014-03-28 | 2017-11-28 | Ut-Battelle, Llc | Thermal history-based etching |
CN106574223B (zh) | 2014-04-02 | 2019-11-01 | 生化诊断系统公司 | 利用俘获缀合物的免疫测定 |
US9972224B2 (en) | 2014-06-27 | 2018-05-15 | Eastman Chemical Company | Fibers with multicomponent fibers used for coding |
US9863920B2 (en) | 2014-06-27 | 2018-01-09 | Eastman Chemical Company | Fibers with chemical markers and physical features used for coding |
US20150375149A1 (en) | 2014-06-27 | 2015-12-31 | Eastman Chemical Company | Acetate tow and filters with shape and size used for coding |
US20160116466A1 (en) | 2014-10-27 | 2016-04-28 | Chembio Diagnostic Systems, Inc. | Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses |
WO2016134342A1 (en) | 2015-02-20 | 2016-08-25 | Wafergen, Inc. | Method for rapid accurate dispensing, visualization and analysis of single cells |
US20180080929A1 (en) * | 2015-03-24 | 2018-03-22 | National University Corporation Nagoya University | Analytical device |
JP6631771B2 (ja) * | 2015-05-11 | 2020-01-15 | 国立研究開発法人情報通信研究機構 | 微生物分析装置及び微生物分析方法 |
EP3487616B1 (en) | 2016-07-21 | 2023-08-09 | Takara Bio USA, Inc. | Multi-z imaging of wells of multi-well devices and liquid dispensing into the wells |
JP7261481B2 (ja) * | 2017-12-23 | 2023-04-20 | 国立大学法人 東京大学 | アレイ及びその使用 |
CA3095292A1 (en) | 2018-04-02 | 2019-10-10 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
GB2582906B (en) * | 2019-04-01 | 2022-09-07 | Ip2Ipo Innovations Ltd | Electrochemical sensor cable |
WO2020206170A1 (en) | 2019-04-02 | 2020-10-08 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
CN114181804A (zh) * | 2022-02-15 | 2022-03-15 | 深圳市研元生物科技有限公司 | 一种基因芯片及其制备和使用方法 |
Family Cites Families (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4238757A (en) | 1976-03-19 | 1980-12-09 | General Electric Company | Field effect transistor for detection of biological reactions |
US4459360A (en) | 1981-10-05 | 1984-07-10 | Mast Medical Industries, Ltd. | Multiple-component binding assay system and method of making and using it |
US4623355A (en) | 1984-03-16 | 1986-11-18 | Sawruk Stephen D | Prosthetic axon |
US4708931A (en) | 1984-06-01 | 1987-11-24 | Regents Of University Of California | Laminated rod having alternating detection and spacer layers for binding assays |
US4859538A (en) | 1986-11-20 | 1989-08-22 | Ribi Hans O | Novel lipid-protein compositions and articles and methods for their preparation |
US4896363A (en) | 1987-05-28 | 1990-01-23 | Thumbscan, Inc. | Apparatus and method for matching image characteristics such as fingerprint minutiae |
US5540828A (en) | 1987-06-08 | 1996-07-30 | Yacynych; Alexander | Method for making electrochemical sensors and biosensors having a polymer modified surface |
US4914022A (en) | 1987-10-21 | 1990-04-03 | Amc Cancer Research Center | Method for preparing multiple tissue samples for microscopic investigation and testing |
US4981653A (en) | 1988-10-06 | 1991-01-01 | Miles Inc. | Self-indicating strip |
US5527681A (en) | 1989-06-07 | 1996-06-18 | Affymax Technologies N.V. | Immobilized molecular synthesis of systematically substituted compounds |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
US5252743A (en) | 1989-11-13 | 1993-10-12 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
DE4024545A1 (de) * | 1990-08-02 | 1992-02-06 | Boehringer Mannheim Gmbh | Verfahren und vorrichtung zum dosierten zufuehren einer biochemischen analysefluessigkeit auf ein target |
US5264565A (en) | 1991-01-22 | 1993-11-23 | Affymax Technologies, N.V. | Nucleic acid encoding the D2 /Ml chimeric receptor |
GB2262163B (en) | 1991-03-09 | 1995-12-20 | Flor Henry Michel | Whole cell sheet photometer |
US5186824A (en) | 1991-09-04 | 1993-02-16 | Large Scale Biology Corporation | System for solid phase reactions |
US5273656A (en) | 1991-09-04 | 1993-12-28 | Large Scale Biology Corporation | System for solid phase reactions |
US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
US5324633A (en) | 1991-11-22 | 1994-06-28 | Affymax Technologies N.V. | Method and apparatus for measuring binding affinity |
EP0624059A4 (en) | 1991-11-22 | 1994-12-21 | Affymax Technologies N.V. | Combinatorial strategies for polymer synthesis. |
US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
US5302707A (en) | 1992-03-26 | 1994-04-12 | Affymax Technologies N.V. | 5-fluorouridine nucleoside phosphate compounds |
US5728802A (en) | 1992-05-06 | 1998-03-17 | Affymax Technologies N.V. | Peptides and compounds that bind selectins including endothelium leukocyte adhesion molecule 1 (ELAM-1) |
US5648458A (en) | 1992-05-06 | 1997-07-15 | Affymax Technologies N.V. | Peptides and compounds that bind to ELAM-1 |
US5622944A (en) | 1992-06-12 | 1997-04-22 | Affymax Technologies N.V. | Testosterone prodrugs for improved drug delivery |
US5607691A (en) | 1992-06-12 | 1997-03-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
US5585275A (en) | 1992-09-02 | 1996-12-17 | Arris Pharmaceutical Corporation | Pilot apparatus for peptide synthesis and screening |
US5420328A (en) | 1992-09-11 | 1995-05-30 | Affymax Technologies, N.V. | Methods for the synthesis of phosphonate esters |
US5491074A (en) | 1993-04-01 | 1996-02-13 | Affymax Technologies Nv | Association peptides |
US5484639A (en) * | 1993-04-15 | 1996-01-16 | Shaw Industires, Inc. | Carpet and carpet backing with directional guide |
US6027880A (en) | 1995-08-02 | 2000-02-22 | Affymetrix, Inc. | Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis |
US20020048749A1 (en) | 1998-04-15 | 2002-04-25 | Robert J. Lipshutz | Methods for polymorphism identifcation and profiling |
US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
EP0711303B2 (en) | 1993-07-30 | 2009-06-10 | Affymax, Inc. | Biotinylation of proteins |
US5362899A (en) | 1993-09-09 | 1994-11-08 | Affymax Technologies, N.V. | Chiral synthesis of alpha-aminophosponic acids |
EP0725682B1 (en) | 1993-10-28 | 2002-03-20 | Houston Advanced Research Center | Microfabricated, flowthrough porous apparatus |
US5922545A (en) | 1993-10-29 | 1999-07-13 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
US5880096A (en) | 1994-02-02 | 1999-03-09 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-1 receptor |
US5786331A (en) | 1994-02-02 | 1998-07-28 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-1 receptor |
US5608035A (en) | 1994-02-02 | 1997-03-04 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-1 receptor |
US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
US5571639A (en) | 1994-05-24 | 1996-11-05 | Affymax Technologies N.V. | Computer-aided engineering system for design of sequence arrays and lithographic masks |
US5635597A (en) | 1994-05-27 | 1997-06-03 | Affymax Technologies, N.V. | Peptides that bind IL-2 receptors |
EP0695941B1 (en) | 1994-06-08 | 2002-07-31 | Affymetrix, Inc. | Method and apparatus for packaging a chip |
US5817751A (en) | 1994-06-23 | 1998-10-06 | Affymax Technologies N.V. | Method for synthesis of diketopiperazine and diketomorpholine derivatives |
US5990112A (en) | 1996-06-18 | 1999-11-23 | Affymax Technologies N.V. | Inhibitors of metalloproteases pharmaceutical compositions comprising same and methods of their use |
DE69531545T2 (de) | 1994-06-23 | 2004-06-24 | Affymax Technologies N.V., Willemstad | Photolabile verbindungen und verfahren für deren verwendung |
US6060288A (en) | 1994-08-03 | 2000-05-09 | Mosaic Technologies | Method for performing amplification of nucleic acid on supports |
US5506420A (en) | 1994-09-14 | 1996-04-09 | The Regents Of The University Of California | Semiconductor bio-electronic devices incorporating biochemical stabilization layers |
US5710000A (en) | 1994-09-16 | 1998-01-20 | Affymetrix, Inc. | Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping |
JP3342590B2 (ja) | 1994-10-20 | 2002-11-11 | 株式会社サンギ | 半導体集積回路 |
US6600996B2 (en) | 1994-10-21 | 2003-07-29 | Affymetrix, Inc. | Computer-aided techniques for analyzing biological sequences |
US6974666B1 (en) | 1994-10-21 | 2005-12-13 | Appymetric, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
US5795716A (en) | 1994-10-21 | 1998-08-18 | Chee; Mark S. | Computer-aided visualization and analysis system for sequence evaluation |
SE9404166D0 (sv) | 1994-11-30 | 1994-11-30 | Pharmacia Biotech Ab | Multifunctional surfaces |
US5655560A (en) | 1994-12-16 | 1997-08-12 | Affymax Technologies N.V. | Clog-free valving system |
US5599695A (en) | 1995-02-27 | 1997-02-04 | Affymetrix, Inc. | Printing molecular library arrays using deprotection agents solely in the vapor phase |
US5961923A (en) | 1995-04-25 | 1999-10-05 | Irori | Matrices with memories and uses thereof |
US6025129A (en) | 1995-04-25 | 2000-02-15 | Irori | Remotely programmable matrices with memories and uses thereof |
US5874214A (en) | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
US5751629A (en) | 1995-04-25 | 1998-05-12 | Irori | Remotely programmable matrices with memories |
US5925562A (en) | 1995-04-25 | 1999-07-20 | Irori | Remotely programmable matrices with memories |
US5624711A (en) | 1995-04-27 | 1997-04-29 | Affymax Technologies, N.V. | Derivatization of solid supports and methods for oligomer synthesis |
US5690894A (en) | 1995-05-23 | 1997-11-25 | The Regents Of The University Of California | High density array fabrication and readout method for a fiber optic biosensor |
US5654276A (en) | 1995-06-07 | 1997-08-05 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
US5668110A (en) | 1995-06-07 | 1997-09-16 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
US5968740A (en) | 1995-07-24 | 1999-10-19 | Affymetrix, Inc. | Method of Identifying a Base in a Nucleic Acid |
US5759779A (en) | 1995-08-29 | 1998-06-02 | Dehlinger; Peter J. | Polynucleotide-array assay and methods |
US5733729A (en) | 1995-09-14 | 1998-03-31 | Affymetrix, Inc. | Computer-aided probability base calling for arrays of nucleic acid probes on chips |
US5843655A (en) | 1995-09-18 | 1998-12-01 | Affymetrix, Inc. | Methods for testing oligonucleotide arrays |
US5763175A (en) | 1995-11-17 | 1998-06-09 | Lynx Therapeutics, Inc. | Simultaneous sequencing of tagged polynucleotides |
US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
US5814524A (en) * | 1995-12-14 | 1998-09-29 | Trustees Of Tufts College | Optical sensor apparatus for far-field viewing and making optical analytical measurements at remote locations |
US6022963A (en) | 1995-12-15 | 2000-02-08 | Affymetrix, Inc. | Synthesis of oligonucleotide arrays using photocleavable protecting groups |
US6013440A (en) | 1996-03-11 | 2000-01-11 | Affymetrix, Inc. | Nucleic acid affinity columns |
US6458530B1 (en) | 1996-04-04 | 2002-10-01 | Affymetrix Inc. | Selecting tag nucleic acids |
JPH1099085A (ja) | 1996-05-16 | 1998-04-21 | Affymetrix Inc | ヒトミトコンドリアdnaの多形性 |
US6057100A (en) * | 1996-06-07 | 2000-05-02 | Eos Biotechnology, Inc. | Oligonucleotide arrays |
US5932579A (en) | 1996-06-18 | 1999-08-03 | Affymax Technologies N.V. | Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use |
WO1998002601A1 (fr) | 1996-07-15 | 1998-01-22 | Sumitomo Metal Industries, Ltd. | Equipement de croissance de cristaux et procede pour la croissance de cristaux utilisant cet equipement |
AU5505498A (en) | 1996-12-19 | 1998-07-15 | Telefonaktiebolaget Lm Ericsson (Publ) | Flip-chip type connection with elastic contacts |
US5993627A (en) | 1997-06-24 | 1999-11-30 | Large Scale Biology Corporation | Automated system for two-dimensional electrophoresis |
US6037186A (en) * | 1997-07-16 | 2000-03-14 | Stimpson; Don | Parallel production of high density arrays |
US6177282B1 (en) | 1997-08-12 | 2001-01-23 | Mcintyre John A. | Antigens embedded in thermoplastic |
AU733589B2 (en) * | 1997-09-11 | 2001-05-17 | Bioventures, Inc. | Method of making high density arrays |
EP0926260A3 (en) | 1997-12-12 | 2001-04-11 | Matsushita Electric Industrial Co., Ltd. | Using antibody - antigen interaction for formation of a patterened metal film |
US5945522A (en) | 1997-12-22 | 1999-08-31 | Genset | Prostate cancer gene |
US6093302A (en) | 1998-01-05 | 2000-07-25 | Combimatrix Corporation | Electrochemical solid phase synthesis |
US20020006604A1 (en) * | 1998-02-21 | 2002-01-17 | Alan W Schwabacher | One dimensional compound arrays and a method for assaying them |
US6210910B1 (en) | 1998-03-02 | 2001-04-03 | Trustees Of Tufts College | Optical fiber biosensor array comprising cell populations confined to microcavities |
US6130046A (en) | 1998-05-04 | 2000-10-10 | Affymetrix, Inc. | Techniques for synthesis integrity evaluation utilizing cycle fidelity probes |
US6525185B1 (en) | 1998-05-07 | 2003-02-25 | Affymetrix, Inc. | Polymorphisms associated with hypertension |
DE19823454A1 (de) | 1998-05-18 | 1999-11-25 | Epigenomics Gmbh | Verfahren zur photolithographischen Herstellung von DNA, PNA und Protein Chips |
US6271957B1 (en) | 1998-05-29 | 2001-08-07 | Affymetrix, Inc. | Methods involving direct write optical lithography |
EP1632496A1 (en) | 1998-06-22 | 2006-03-08 | Affymetrix, Inc. | Reagents and methods for solid phase synthesis and display |
US6129896A (en) * | 1998-12-17 | 2000-10-10 | Drawn Optical Components, Inc. | Biosensor chip and manufacturing method |
US6103518A (en) | 1999-03-05 | 2000-08-15 | Beecher Instruments | Instrument for constructing tissue arrays |
US6713309B1 (en) * | 1999-07-30 | 2004-03-30 | Large Scale Proteomics Corporation | Microarrays and their manufacture |
-
2000
- 2000-01-13 US US09/482,460 patent/US6713309B1/en not_active Expired - Fee Related
- 2000-07-28 EP EP00955276A patent/EP1204867A4/en not_active Withdrawn
- 2000-07-28 MX MXPA02000992A patent/MXPA02000992A/es unknown
- 2000-07-28 KR KR1020027001337A patent/KR20020042632A/ko not_active Application Discontinuation
- 2000-07-28 IL IL14768300A patent/IL147683A0/xx unknown
- 2000-07-28 AU AU67502/00A patent/AU6750200A/en not_active Abandoned
- 2000-07-28 WO PCT/US2000/020695 patent/WO2001009607A1/en not_active Application Discontinuation
- 2000-07-28 CA CA 2376489 patent/CA2376489A1/en not_active Abandoned
- 2000-07-28 US US09/628,339 patent/US6846635B1/en not_active Expired - Fee Related
- 2000-07-28 JP JP2001514567A patent/JP2003527569A/ja active Pending
-
2001
- 2001-06-14 US US09/880,019 patent/US6887701B2/en not_active Expired - Fee Related
-
2002
- 2002-04-05 JP JP2002103652A patent/JP2003014756A/ja active Pending
- 2002-04-05 JP JP2002103649A patent/JP2003014753A/ja active Pending
- 2002-04-05 JP JP2002103642A patent/JP2003014750A/ja active Pending
- 2002-04-05 JP JP2002103654A patent/JP2003014758A/ja active Pending
- 2002-04-05 JP JP2002103647A patent/JP2003004738A/ja active Pending
- 2002-04-05 JP JP2002103644A patent/JP2003014752A/ja active Pending
- 2002-04-05 JP JP2002103648A patent/JP2003028869A/ja active Pending
- 2002-04-05 JP JP2002103655A patent/JP2003014759A/ja active Pending
- 2002-04-05 JP JP2002103645A patent/JP2003028868A/ja active Pending
- 2002-04-05 JP JP2002103643A patent/JP2003014751A/ja active Pending
- 2002-04-05 JP JP2002103653A patent/JP2003014757A/ja active Pending
- 2002-04-05 JP JP2002103650A patent/JP2003014754A/ja active Pending
- 2002-04-05 JP JP2002103651A patent/JP2003014755A/ja active Pending
- 2002-04-05 JP JP2002103656A patent/JP2003028870A/ja active Pending
- 2002-04-05 JP JP2002103646A patent/JP2003028879A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2003014758A (ja) | 2003-01-15 |
AU6750200A (en) | 2001-02-19 |
US6846635B1 (en) | 2005-01-25 |
JP2003028870A (ja) | 2003-01-29 |
CA2376489A1 (en) | 2001-02-08 |
JP2003014750A (ja) | 2003-01-15 |
JP2003028869A (ja) | 2003-01-29 |
WO2001009607A8 (en) | 2002-02-07 |
US20010041339A1 (en) | 2001-11-15 |
JP2003014759A (ja) | 2003-01-15 |
US6887701B2 (en) | 2005-05-03 |
JP2003014752A (ja) | 2003-01-15 |
JP2003527569A (ja) | 2003-09-16 |
EP1204867A1 (en) | 2002-05-15 |
EP1204867A4 (en) | 2006-05-10 |
JP2003004738A (ja) | 2003-01-08 |
JP2003014751A (ja) | 2003-01-15 |
US6713309B1 (en) | 2004-03-30 |
JP2003028868A (ja) | 2003-01-29 |
JP2003014755A (ja) | 2003-01-15 |
JP2003014754A (ja) | 2003-01-15 |
JP2003014756A (ja) | 2003-01-15 |
JP2003014753A (ja) | 2003-01-15 |
JP2003014757A (ja) | 2003-01-15 |
JP2003028879A (ja) | 2003-01-29 |
WO2001009607A1 (en) | 2001-02-08 |
KR20020042632A (ko) | 2002-06-05 |
MXPA02000992A (es) | 2003-07-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL147683A0 (en) | Microarrays and their manufacture | |
HRP20060251B1 (hr) | Supstituirani oksazolidinoni i njihova uporaba | |
GB9903584D0 (en) | Modified calycins | |
GB9919764D0 (en) | Thyristors and their manufacture | |
EP1077996A4 (en) | GENE EDG3sb HUMAN | |
IL128193A0 (en) | Rhamnosyl-transferase gene and uses thereof | |
EP1070497A4 (en) | METHOD OF MANUFACTURING TABLETS AND TABLETS | |
GB9927590D0 (en) | Microarray slides | |
EP1241256A4 (en) | NEW GENE AND USE | |
GB9912563D0 (en) | Polyketides and their synthesis | |
GB2356680B (en) | Tubes and their manufacture | |
PL354184A1 (en) | The prv-1 gene and use thereof | |
EP1189920A4 (en) | FAMILY OF GENES CAMELLO AND THE USE OF THE SAID GENES | |
AU140357S (en) | Section | |
HUP0104954A3 (en) | Prv-1 gene and the use thereof | |
GB9929581D0 (en) | Comjpositions and their use | |
GB9907469D0 (en) | Labels and manufacture thereof | |
IL146940A0 (en) | Novel calpains and their use | |
DE60034798D1 (en) | Mischer | |
GB9918833D0 (en) | Mat manufacture | |
GB0106063D0 (en) | Libraries and their use | |
IL149638A0 (en) | S-allylmercaptoglutathione and uses thereof | |
GB9916675D0 (en) | Enigma-sip and enigma-cell | |
GB2353743B (en) | Improvements in the manufacture of cases | |
GB9924508D0 (en) | Labels and manufacture thereof |