IL144269A0 - Schizochytrium pks genes - Google Patents

Schizochytrium pks genes

Info

Publication number
IL144269A0
IL144269A0 IL14426900A IL14426900A IL144269A0 IL 144269 A0 IL144269 A0 IL 144269A0 IL 14426900 A IL14426900 A IL 14426900A IL 14426900 A IL14426900 A IL 14426900A IL 144269 A0 IL144269 A0 IL 144269A0
Authority
IL
Israel
Prior art keywords
pks genes
schizochytrium pks
schizochytrium
genes
pks
Prior art date
Application number
IL14426900A
Other languages
English (en)
Original Assignee
Omegatech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omegatech Inc filed Critical Omegatech Inc
Publication of IL144269A0 publication Critical patent/IL144269A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IL14426900A 1999-01-14 2000-01-14 Schizochytrium pks genes IL144269A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/231,899 US6566583B1 (en) 1997-06-04 1999-01-14 Schizochytrium PKS genes
PCT/US2000/000956 WO2000042195A2 (en) 1999-01-14 2000-01-14 Schizochytrium pks genes

Publications (1)

Publication Number Publication Date
IL144269A0 true IL144269A0 (en) 2002-05-23

Family

ID=22871074

Family Applications (4)

Application Number Title Priority Date Filing Date
IL14426900A IL144269A0 (en) 1999-01-14 2000-01-14 Schizochytrium pks genes
IL144269A IL144269A (en) 1999-01-14 2001-07-11 Schizochytrium pks genes
IL188590A IL188590A (en) 1999-01-14 2008-01-03 Genes for pks proteins having a chain length factor and a noble transfer activity, plant and antimicrobial cells containing them and their methods.
IL224871A IL224871A (en) 1999-01-14 2013-02-21 Genes - Schizectrium pks

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL144269A IL144269A (en) 1999-01-14 2001-07-11 Schizochytrium pks genes
IL188590A IL188590A (en) 1999-01-14 2008-01-03 Genes for pks proteins having a chain length factor and a noble transfer activity, plant and antimicrobial cells containing them and their methods.
IL224871A IL224871A (en) 1999-01-14 2013-02-21 Genes - Schizectrium pks

Country Status (10)

Country Link
US (6) US6566583B1 (enExample)
EP (4) EP2333072B1 (enExample)
JP (3) JP2002534123A (enExample)
BR (1) BR0008760A (enExample)
CA (1) CA2359629C (enExample)
ES (1) ES2427017T3 (enExample)
HK (1) HK1041292A1 (enExample)
IL (4) IL144269A0 (enExample)
MX (1) MX252154B (enExample)
WO (1) WO2000042195A2 (enExample)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
AU774306B2 (en) 1999-01-05 2004-06-24 Trustees Of Boston University Improved nucleic acid cloning
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7217856B2 (en) * 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7271315B2 (en) * 1999-01-14 2007-09-18 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US20070244192A1 (en) * 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7247461B2 (en) 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US7211418B2 (en) * 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
DK1252324T3 (da) 2000-01-19 2010-12-20 Martek Biosciences Corp Solventfri ekstraktionsfremgangsmåde
WO2001054510A1 (en) 2000-01-28 2001-08-02 Omegatech, Inc. Enhanced production of lipids containing polyenoic fatty acids by high density cultures of eukaryotic microbes in fermentors
TWI426126B (zh) * 2001-04-16 2014-02-11 Dsm Ip Assets Bv 多不飽和脂肪酸（ｐｕｆａ）聚乙醯合成酶系統及其用途（二）
EP2368445A1 (en) 2002-06-18 2011-09-28 Martek Biosciences Corporation Stable Emulsions of Oils in Aqueous Solutions and Methods for Producing Same
AU2003296638B2 (en) 2002-12-19 2009-06-11 University Of Bristol Method for the production of polyunsaturated fatty acids
EP1599582B1 (de) 2003-02-27 2011-07-27 BASF Plant Science GmbH Verfahren zur herstellung mehrfach ungesättigter fettsäuren
WO2004080196A2 (en) * 2003-03-07 2004-09-23 Advanced Bionutrition Corporation Feed formulation for terrestrial and aquatic animals
EP1623008B1 (en) * 2003-03-26 2014-07-30 DSM IP Assets B.V. Pufa polyketide synthase systems and uses thereof
ES2421138T3 (es) 2003-03-31 2013-08-29 University Of Bristol Nuevas aciltransferasas vegetales específicas para ácidos grasos poliinsaturados de cadena larga
US7646815B2 (en) * 2003-07-15 2010-01-12 Lsi Corporation Intra estimation chroma mode 0 sub-block dependent prediction
US7208590B2 (en) * 2003-07-15 2007-04-24 Abbott Laboratories Genes involved in polyketide synthase pathways and uses thereof
DE102004017369A1 (de) * 2004-04-08 2005-11-03 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Screeningverfahren zur Identifizierung von PUFA-PKS in Proben
DE102004017370A1 (de) * 2004-04-08 2005-10-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh PUFA-PKS Gene aus Ulkenia
CN103451246B (zh) 2004-04-22 2018-02-16 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
CA2563875C (en) 2004-04-22 2015-06-30 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
WO2006092449A2 (en) * 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
EP3467096B1 (en) 2005-06-07 2022-01-12 DSM Nutritional Products AG Eukaryotic microorganisms for producing lipids and antioxidants
JP4819888B2 (ja) 2005-07-01 2011-11-24 マーテック バイオサイエンシーズ コーポレーション 多価不飽和脂肪酸含有油産物ならびにその使用および産生
JP4943678B2 (ja) * 2005-08-01 2012-05-30 国立大学法人北海道大学 細胞の脂肪酸組成を改変する方法およびその利用
CA2630173C (en) 2005-11-18 2018-01-09 Commonwealth Scientific And Industrial Research Organisation Feedstuffs for aquaculture comprising stearidonic acid
EP2653557A1 (en) 2006-03-15 2013-10-23 DSM IP Assets B.V. Plant seed oils containing polyunsaturated fatty acids
EP2007215A4 (en) * 2006-04-11 2011-04-13 Martek Biosciences Corp FOODSTUFFS WITH LONG-CHAIN MULTIPLE-UNSATURATED FATTY ACIDS AND METHOD FOR THE PRODUCTION THEREOF
EP2034973B2 (en) 2006-06-22 2022-01-19 DSM IP Assets B.V. Encapsulated labile compound compositions and methods of making the same
US9023616B2 (en) * 2006-08-01 2015-05-05 Dsm Nutritional Products Ag Oil producing microbes and method of modification thereof
AU2007289233A1 (en) 2006-08-29 2008-03-06 Dsm Ip Assets B.V. Use of DPA(n-6) oils in infant formula
BRPI0716075A2 (pt) 2006-08-29 2013-08-06 Commw Scient Ind Res Org sÍntese de Ácidos graxos
AU2008206403A1 (en) * 2007-01-12 2008-07-24 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms
US20090023808A1 (en) * 2007-06-29 2009-01-22 Martek Biosciences Corporation Production and Purification of Esters of Polyunsaturated Fatty Acids
CN101802220B (zh) 2007-07-26 2013-07-31 加利福尼亚太平洋生物科学股份有限公司 分子冗余测序法
ES2748136T3 (es) 2007-10-15 2020-03-13 United Animal Health Inc Método para aumentar el rendimiento de las crías
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
US20110076379A1 (en) * 2008-06-13 2011-03-31 Means Michael M High omega saturated fat free meat products
BR122021003836B1 (pt) 2008-11-18 2022-02-01 Commonwealth Scientific And Industrial Research Organisation Polinucleotídeo isolado e/ou exógeno que não ocorre de forma natural, vetor e método para produzir óleo contendo ácidos graxos insaturados
TWI600762B (zh) 2009-03-19 2017-10-01 Ｄｓｍ智慧財產有限公司 多不飽和脂肪酸合成酶核酸分子及多肽，組成物，以及其製造方法與用途
AU2010247438B2 (en) 2009-05-13 2015-01-29 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
AU2010298004B2 (en) 2009-09-27 2016-02-25 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
WO2011063363A2 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
US20130122541A1 (en) * 2010-01-27 2013-05-16 The Regents Of The University Of Colorado Microorganism production of high-value chemical products, and related compositions, methods and systems
TW201144442A (en) 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
WO2011153246A2 (en) * 2010-06-01 2011-12-08 Martek Biosciences Corporation Extraction of lipid from cells and products therefrom
NO2585603T3 (enExample) 2010-06-25 2018-05-19
TW201307553A (zh) 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術
KR102197208B1 (ko) 2012-06-15 2021-01-04 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 식물 세포에서 장쇄 다중불포화 지방산의 생성
CN104520313A (zh) 2012-08-03 2015-04-15 巴斯夫植物科学有限公司 新的酶、酶组合物及其用途
MX2015001780A (es) 2012-08-10 2015-09-28 Opx Biotechnologies Inc Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos.
US9873880B2 (en) 2013-03-13 2018-01-23 Dsm Nutritional Products Ag Engineering microorganisms
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
BR112015023583A2 (pt) 2013-03-15 2017-08-22 Dow Global Technologies Llc Método para vaporização 3-hp a partir de uma solução, vapor, solução 3-hp condensada, composição, produto químico à jusante, produto de consumo, sistema para purificação de 3-hp, método para produzir uma solução de 3-hp, método para decompor a amônia de 3-hp (a3-hp) e método para decompor a3-hp
JP6603658B2 (ja) 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
TW201525136A (zh) 2013-11-26 2015-07-01 Dow Agrosciences Llc 利用破囊壺菌ＰＵＦＡ合成酶於油籽作物中生成ω－３長鏈多不飽和脂肪酸
EA037817B1 (ru) 2013-12-18 2021-05-25 Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты
NZ721415A (en) 2013-12-20 2022-08-26 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
MX370606B (es) 2013-12-20 2019-12-18 Dsm Ip Assets Bv Procedimientos para obtener aceite microbiano a partir de células microbianas.
EP3083546B1 (en) 2013-12-20 2022-03-02 DSM IP Assets B.V. Processes for obtaining microbial oil from microbial cells
SG11201605052XA (en) 2013-12-20 2016-07-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
JP2017500037A (ja) 2013-12-20 2017-01-05 ディーエスエム アイピー アセッツ ビー．ブイ． 微生物細胞から微生物油を入手するための方法
ES2721269T3 (es) 2014-01-28 2019-07-30 Dsm Ip Assets Bv Factores para la producción y acumulación de ácidos grasos poliinsaturados (PUFA) obtenidos con PUFA sintasas
US10131897B2 (en) 2014-03-03 2018-11-20 Synthetics Genomics, Inc. Molecules associated with fatty acid biosynthetic pathways and uses thereof
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
AU2016228545A1 (en) * 2015-03-12 2017-09-21 Synthetic Genomics. Inc. Microorganisms for fatty acid production using elongase and desaturase enzymes
AR109245A1 (es) 2016-05-12 2018-11-14 Basf Plant Science Co Gmbh Métodos para optimizar la producción de metabolitos en plantas genéticamente modificadas y para procesar estas plantas
JP6966040B2 (ja) 2016-05-12 2021-11-10 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. 微細藻類中でのオメガ−３多価不飽和脂肪酸産生を増加させる方法
JP2020506702A (ja) 2017-02-02 2020-03-05 カーギル インコーポレイテッド Ｃ６−ｃ１０脂肪酸誘導体を生成する遺伝子組み換え細胞
US11248244B2 (en) * 2017-05-10 2022-02-15 Nanjing University Of Technology Schizochytrium limacinum strain, building method therefor and application thereof
US11866788B2 (en) 2018-05-08 2024-01-09 Sanford Burnham Prebys Medical Discovery Institute Role of PVT1 in the diagnosis and treatment of MYC-driven cancer
WO2020032261A1 (ja) * 2018-08-10 2020-02-13 協和発酵バイオ株式会社 エイコサペンタエン酸を生産する微生物及びエイコサペンタエン酸の製造法
JP7540943B2 (ja) * 2018-08-10 2024-08-27 協和発酵バイオ株式会社 多価不飽和脂肪酸を生産する微生物及び多価不飽和脂肪酸の製造法
EP4031253B1 (en) 2019-09-19 2025-11-05 Sanford Burnham Prebys Medical Discovery Institute Methods and compositions for treating myc-driven cancers

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034322A (en) 1983-01-17 1991-07-23 Monsanto Company Chimeric genes suitable for expression in plant cells
US4792523A (en) 1984-08-31 1988-12-20 Cetus Corporation 3'Expression enhancing fragments and method
US4743548A (en) 1984-09-25 1988-05-10 Calgene, Inc. Plant cell microinjection technique
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
US4943674A (en) 1987-05-26 1990-07-24 Calgene, Inc. Fruit specific transcriptional factors
GB2178752B (en) 1985-07-12 1989-10-11 Unilever Plc Substitute milk fat
US4940835A (en) 1985-10-29 1990-07-10 Monsanto Company Glyphosate-resistant plants
US5068193A (en) 1985-11-06 1991-11-26 Calgene, Inc. Novel method and compositions for introducing alien DNA in vivo
US4795855A (en) 1985-11-14 1989-01-03 Joanne Fillatti Transformation and foreign gene expression with woody species
US5188958A (en) 1986-05-29 1993-02-23 Calgene, Inc. Transformation and foreign gene expression in brassica species
US5565347A (en) 1986-06-10 1996-10-15 Calgene, Inc. Transformation and foreign gene expression with plant species
US5246841A (en) 1986-12-26 1993-09-21 Sagami Chemical Research Center Microbial process for production of eicosapentaenoic acid
AU612133B2 (en) 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
DE3719097C1 (de) 1987-06-06 1988-06-09 Fratzer Uwe Arzneimittel,enthaltend Eicosapentaensaeure und Docosahexaensaeure als ungesaettigte Fettsaeuren sowie Vitamin E
US5011770A (en) 1987-09-04 1991-04-30 Molecular Devices, Inc. DNA detection method
US4999422A (en) 1988-04-15 1991-03-12 Biogen, N.V. Continuous method of refolding proteins
US5565346A (en) 1988-07-27 1996-10-15 Calgene, Inc. Transformation and regeneration system for legumes
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5162215A (en) 1988-09-22 1992-11-10 Amgen Inc. Method of gene transfer into chickens and other avian species
DE69033816T2 (de) 1989-02-24 2002-08-08 Monsanto Technology Llc., St. Louis Synthetische pflanzengene und verfahren zu ihrer herstellung
US5106739A (en) 1989-04-18 1992-04-21 Calgene, Inc. CaMv 355 enhanced mannopine synthase promoter and method for using same
US5175095A (en) 1989-07-19 1992-12-29 Calgene, Inc. Ovary-tissue transcriptional factors
US5639790A (en) 1991-05-21 1997-06-17 Calgene, Inc. Plant medium-chain thioesterases
US5798259A (en) 1992-05-15 1998-08-25 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
CA2113557A1 (en) 1992-05-15 1993-11-25 Kazunaga Yazawa Gene which codes for eicosapentaenoic acid synthetase group and process for producing eicosapentaenoic acid
US5683898A (en) 1992-05-15 1997-11-04 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
US5310242A (en) 1992-09-28 1994-05-10 Golder Kimberly A Portable infant seat
ES2148323T3 (es) 1993-02-26 2000-10-16 Calgene Llc Sistema de expresion de un gen a base de geminivirus.
DE4323727A1 (de) * 1993-07-15 1995-03-09 Boehringer Mannheim Gmbh Verfahren zur Identifizierung von menschlichen und tierischen Zellen mit der Fähigkeit zu unbegrenzter Proliferation oder zur Tumorbildung
US5672491A (en) 1993-09-20 1997-09-30 The Leland Stanford Junior University Recombinant production of novel polyketides
CA2184687A1 (en) 1994-03-09 1995-09-14 Pedro Antonio Prieto Humanized milk
WO1996006160A1 (en) 1994-08-24 1996-02-29 Meiji Milk Products Co., Ltd. Method of culturing avian cells and cell line obtained thereby
FR2726003B1 (fr) 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
AU4400196A (en) 1995-01-13 1996-07-31 Sagami Chemical Research Center Genes coding for biosynthetic enzyme group for icosapentaenoic acid and process for producing icosapentaenoic acid
US6582941B1 (en) * 1995-04-17 2003-06-24 Japan As Represented By Director-General Of Agency Of Industrial Science And Technology Microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fatty acids by using the microorganisms
GB9508023D0 (en) 1995-04-20 1995-06-07 Scotia Holdings Plc Fatty acid derivatives
WO1998001565A1 (en) * 1996-07-10 1998-01-15 Sagami Chemical Research Center Process for producing icosapentaenoic acid by genetic recombination
US6033883A (en) 1996-12-18 2000-03-07 Kosan Biosciences, Inc. Production of polyketides in bacteria and yeast
EP0996732B1 (en) * 1997-04-11 2005-06-15 Calgene LLC Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
WO1998055625A1 (en) 1997-06-04 1998-12-10 Calgene, Llc Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
US6677145B2 (en) 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US20070244192A1 (en) 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US7271315B2 (en) 1999-01-14 2007-09-18 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
AU2001268296B2 (en) 2000-06-08 2006-05-25 Miami University Fatty acid elongase 3-ketoacyl coa synthase polypeptides
US20040010817A1 (en) 2000-07-21 2004-01-15 Washington State University Research Foundation Plant acyl-CoA synthetases
ES2399806T3 (es) 2000-09-28 2013-04-03 Bioriginal Food & Science Corp. Miembro de la familia de desaturasa de ácido graso fad6 y usos del mismo
TWI426126B (zh) 2001-04-16 2014-02-11 Dsm Ip Assets Bv 多不飽和脂肪酸（ｐｕｆａ）聚乙醯合成酶系統及其用途（二）
TWI377253B (en) 2001-04-16 2012-11-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
US7045683B2 (en) * 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
EP1392623A4 (en) * 2001-05-14 2005-05-04 Martek Biosciences Corp PREPARATION AND USE OF A POLAR LIPID RICH FRACTION CONTAINING HIGHLY UNSATURATED OMEGA-3 AND / OR OMEGA-6 FATTY ACIDS FROM MICROBES, SEEDS OF GENETICALLY MODIFIED PLANTS AND MARINE ORGANISMS
US20040005672A1 (en) 2002-02-22 2004-01-08 Santi Daniel V. Heterologous production of polyketides
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
EP2302060B1 (en) 2002-03-16 2012-07-25 The University of York Desaturases
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US8084074B2 (en) * 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
EP1623008B1 (en) 2003-03-26 2014-07-30 DSM IP Assets B.V. Pufa polyketide synthase systems and uses thereof
ES2421138T3 (es) 2003-03-31 2013-08-29 University Of Bristol Nuevas aciltransferasas vegetales específicas para ácidos grasos poliinsaturados de cadena larga
US7125672B2 (en) 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US7208590B2 (en) 2003-07-15 2007-04-24 Abbott Laboratories Genes involved in polyketide synthase pathways and uses thereof
DE102004060340A1 (de) 2004-07-16 2006-02-09 Basf Plant Science Gmbh Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
EP2345730A1 (en) 2004-09-20 2011-07-20 BASF Plant Science GmbH Arabidopsis genes encoding proteins involved in sugar and lipid metabolism and methods of use
US20080260933A1 (en) * 2004-10-08 2008-10-23 Dow Agroscience Llc Certain Plants with "No Saturate" or Reduced Saturate Levels of Fatty Acids in Seeds, and Oil Derived from the Seeds
AU2005304670B2 (en) * 2004-11-04 2012-03-22 Monsanto Technology Llc Seed oil compositions
AR059376A1 (es) * 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
EP2653557A1 (en) 2006-03-15 2013-10-23 DSM IP Assets B.V. Plant seed oils containing polyunsaturated fatty acids
CA2698311C (en) * 2007-08-31 2016-07-12 Martek Biosciences Corporation Polyunsaturated fatty acid-containing solid fat compositions and uses and production thereof

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