IL143441A0 - Non-naturally occuring antigen arrays and processes for the preparation thereof - Google Patents

Non-naturally occuring antigen arrays and processes for the preparation thereof

Info

Publication number
IL143441A0
IL143441A0 IL14344199A IL14344199A IL143441A0 IL 143441 A0 IL143441 A0 IL 143441A0 IL 14344199 A IL14344199 A IL 14344199A IL 14344199 A IL14344199 A IL 14344199A IL 143441 A0 IL143441 A0 IL 143441A0
Authority
IL
Israel
Prior art keywords
antigen
virus
production
particles
coated
Prior art date
Application number
IL14344199A
Other languages
English (en)
Original Assignee
Cytos Biotechnology Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytos Biotechnology Ag filed Critical Cytos Biotechnology Ag
Publication of IL143441A0 publication Critical patent/IL143441A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14344199A 1998-11-30 1999-11-30 Non-naturally occuring antigen arrays and processes for the preparation thereof IL143441A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11041498P 1998-11-30 1998-11-30
US14278899P 1999-07-08 1999-07-08
PCT/IB1999/001925 WO2000032227A2 (en) 1998-11-30 1999-11-30 Ordered molecular presentation of antigens, method of preparation and use

Publications (1)

Publication Number Publication Date
IL143441A0 true IL143441A0 (en) 2002-04-21

Family

ID=26808005

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14344199A IL143441A0 (en) 1998-11-30 1999-11-30 Non-naturally occuring antigen arrays and processes for the preparation thereof
IL143441A IL143441A (en) 1998-11-30 2001-05-29 Non-naturally occurring antigen arrays and processes for the preparation thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL143441A IL143441A (en) 1998-11-30 2001-05-29 Non-naturally occurring antigen arrays and processes for the preparation thereof

Country Status (17)

Country Link
US (1) US7229624B2 (zh)
EP (1) EP1135162B1 (zh)
JP (1) JP2010510960A (zh)
CN (2) CN100534529C (zh)
AT (1) ATE412434T1 (zh)
AU (1) AU768807B2 (zh)
BR (1) BR9915771A (zh)
CA (1) CA2354183A1 (zh)
DE (1) DE69939836D1 (zh)
DK (1) DK1135162T3 (zh)
ES (1) ES2317711T3 (zh)
IL (2) IL143441A0 (zh)
MX (1) MXPA01005389A (zh)
NZ (1) NZ512456A (zh)
PL (1) PL192016B1 (zh)
RU (1) RU2245163C2 (zh)
WO (1) WO2000032227A2 (zh)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2347411C (en) 1998-10-21 2012-04-03 The Government Of The United States Of America Virus-like particles for the induction of autoantibodies
US6913749B2 (en) 1998-11-02 2005-07-05 Resistentia Pharmaceuticals Ab Immunogenic polypeptides for inducing anti-self IgE responses
US7476517B2 (en) 1999-06-30 2009-01-13 Evotec Ag Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
US20040014033A1 (en) 1999-06-30 2004-01-22 Evotec Biosystems Ag, A Corporation Of Germany Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
EP1278542A2 (en) * 2000-05-05 2003-01-29 Cytos Biotechnology AG Molecular antigen arrays and vaccines
EP1219705B1 (en) * 2000-12-29 2007-11-28 Evotec AG Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
EP1362109B1 (en) 2001-01-18 2009-06-10 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Recombinant oligomeric protein complexes with enhanced immunogenic potential
US7128911B2 (en) 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
US7094409B2 (en) 2001-01-19 2006-08-22 Cytos Biotechnology Ag Antigen arrays for treatment of allergic eosinophilic diseases
AU2007202761B2 (en) * 2001-01-19 2010-01-21 Kuros Biosciences Ag Molecular antigen array
US7264810B2 (en) 2001-01-19 2007-09-04 Cytos Biotechnology Ag Molecular antigen array
AU2002347404A1 (en) * 2001-09-14 2003-04-01 Cytos Biotechnology Ag In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles
DE60234375D1 (de) * 2001-09-14 2009-12-24 Cytos Biotechnology Ag VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
JP4671389B2 (ja) * 2001-10-05 2011-04-13 サイトス バイオテクノロジー アーゲー アンジオテンシンペプチド−担体複合体およびその使用
MXPA04002644A (es) 2001-10-05 2004-07-08 Cytos Biotechnology Ag Conjugados que portan un peptido de angiotensina y usos de los mismos.
CN100509057C (zh) * 2001-11-07 2009-07-08 赛托斯生物技术公司 用于治疗骨病的抗原阵列
DE60230656D1 (de) * 2001-11-07 2009-02-12 Cytos Biotechnology Ag Antigenraster welche il-5, il-13 oder eotaxin präshilen erkrankungen
WO2003059386A2 (en) * 2002-01-18 2003-07-24 Cytos Biotechnology Ag Prion protein carrier-conjugates
AU2003237528A1 (en) 2002-06-07 2003-12-22 Kentucky Bioprocessing, Llc Flexible vaccine assembly and vaccine delivery platform
ATE489969T1 (de) * 2002-06-20 2010-12-15 Cytos Biotechnology Ag Verpackte virusartige partikel in kombination mit cpg zur verwendung als adjuvantien mit allergenen. herstellungsverfahren und verwendung
CN102061288A (zh) 2002-07-17 2011-05-18 希托斯生物技术股份公司 使用衍生自ap205外壳蛋白的病毒样颗粒的分子抗原阵列
EP2392345A3 (en) 2002-07-18 2012-03-07 Cytos Biotechnology AG Hapten-carrier conjugates comprising virus like particles and uses thereof
CN101711865A (zh) * 2002-07-19 2010-05-26 希托斯生物技术股份公司 含有淀粉样β1-6抗原阵列的疫苗组合物
PL375522A1 (en) * 2002-07-19 2005-11-28 Cytos Biotechnology Ag Ghrelin-carrier conjugates
US20070104726A1 (en) * 2002-08-14 2007-05-10 Avidis Sa Multimeric complexes of antigens and adjuvants
US7537767B2 (en) 2003-03-26 2009-05-26 Cytis Biotechnology Ag Melan-A- carrier conjugates
CA2517675A1 (en) 2003-03-26 2004-10-07 Cytos Biotechnology Ag Packaging of immunostimulatory oligonucleotides into virus-like particles: method of preparation and use
EP1623229A2 (en) * 2003-05-15 2006-02-08 Cytos Biotechnology AG Selection of b cells with specificity of interest: method of preparation and use
US7923109B2 (en) * 2004-01-05 2011-04-12 Board Of Regents, The University Of Texas System Inorganic nanowires
AU2005205181A1 (en) * 2004-01-20 2005-07-28 Cytos Biotechnology Ag Particle-induced ghrelin immune response
AR044603A1 (es) 2004-06-03 2005-09-21 Consejo Nac Invest Cient Tec Proteinas quimericas aisladas de lumazina sintetasa modificada para la presentacion multiple de moleculas y sus aplicaciones
US7862829B2 (en) * 2004-07-09 2011-01-04 University Of North Carolina At Chapel Hill Viral adjuvants
KR20070059207A (ko) 2004-10-05 2007-06-11 사이토스 바이오테크놀로지 아게 Ｖｌｐ-항원 컨쥬게이트 및 백신으로서 그의 용도
JP2008517975A (ja) 2004-10-25 2008-05-29 サイトス バイオテクノロジー アーゲー 胃酸分泌抑制ポリペプチド（ｇｉｐ）抗原アッセイ及びその使用
GB0424563D0 (en) 2004-11-05 2004-12-08 Novartis Ag Organic compounds
KR20070112225A (ko) * 2005-03-18 2007-11-22 사이토스 바이오테크놀로지 아게 고양이 알레르겐 컨쥬게이트 및 그의 용도
CA2623287A1 (en) 2005-09-28 2007-04-12 Cytos Biotechnology Ag Interleukin-1 conjugates and uses thereof
RU2451523C2 (ru) 2005-12-14 2012-05-27 Цитос Биотехнологи Аг Упакованные иммуностимулирующей нуклеиновой кислотой частицы, предназначенные для лечения гиперчувствительности
WO2007092315A2 (en) * 2006-02-03 2007-08-16 The Regents Of The University Of California Immunostimulation by cpg oligonucleotide-virus complexes
EP1987441B1 (en) 2006-02-07 2017-10-04 Ticketmaster Methods and systems for reducing burst usage of a networked computer system
PT2032592E (pt) 2006-06-12 2013-08-28 Cytos Biotechnology Ag Processos para o empacotamento de oligonucleótidos em partículas semelhantes a vírus de bacteriófagos de arn
EP2125854B1 (en) 2006-12-12 2016-10-26 Kuros Biosciences AG Oligonucleotides containing high concentrations of guanine monomers
JP6088123B2 (ja) * 2008-02-01 2017-03-01 アルファ−オー・ペプチドズ・アーゲーＡｌｐｈａ−Ｏ Ｐｅｐｔｉｄｅｓ Ａｇ ワクチンとして有用な自己会合ペプチドナノ粒子
NZ592977A (en) 2008-12-09 2013-01-25 Pfizer Vaccines Llc IgE CH3 PEPTIDE VACCINE
PL222497B1 (pl) 2009-06-26 2016-08-31 Inst Biochemii I Biofizyki Pan Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej
NZ618391A (en) 2009-07-30 2015-07-31 Pfizer Vaccines Llc Antigenic tau peptides and uses thereof
PE20161560A1 (es) 2009-09-03 2017-01-11 Pfizer Vaccines Llc Vacuna de pcsk9
EP2942061A3 (en) 2010-06-07 2016-01-13 Pfizer Vaccines LLC Ige ch3 peptide vaccine
WO2012048115A2 (en) 2010-10-06 2012-04-12 University Of Washington Through Its Center For Commercialization Polypeptides and their use in treating and limiting respiratory syncytial virus infection
CN102146411B (zh) * 2011-01-06 2013-01-02 中国人民解放军第三军医大学第三附属医院 新型双功能抗瘢痕和组织纤维化寡聚核苷酸药物
EP2680883B1 (en) 2011-03-02 2018-09-05 Pfizer Inc Pcsk9 vaccine
WO2013003752A2 (en) 2011-06-30 2013-01-03 University Of Washington Through Its Center For Commercialization Methods for design of epitope scaffolds
MX2014001142A (es) 2011-07-29 2014-02-27 Selecta Biosciences Inc Nanoportadores sinteticos que generan respuestas inmunitarias humorales y de linfocitos t citotoxicos (ctl).
EP2834263B9 (en) 2012-04-05 2019-02-27 University Of Washington Through Its Center For Commercialization Epitope-scaffold immunogens against respiratory syncytial virusm (rsv)
CA2927009C (en) * 2013-10-21 2019-04-23 Drexel University Use of sting agonists to treat chronic hepatitis b virus infection
WO2015123291A1 (en) 2014-02-11 2015-08-20 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Pcsk9 vaccine and methods of using the same
JP6409528B2 (ja) * 2014-11-27 2018-10-24 Jnc株式会社 アミノ基を含むイオン交換基とブチル基を含む疎水性基とを有する多孔性セルロース粒子及びそれを含むクロマトグラフィー担体ならびにｂ型肝炎ウィルスのウィルス様粒子の精製方法
WO2017179025A1 (en) 2016-04-15 2017-10-19 Alk-Abelló A/S Epitope polypeptides of ragweed pollen allergens
GB201616365D0 (en) * 2016-09-27 2016-11-09 Helsingin Yliopisto Non-genetic modification of enveloped viruses
US11633471B2 (en) 2018-03-06 2023-04-25 Unm Rainforest Innovations Compositions and methods for reducing serum triglycerides
CN119286871A (zh) 2018-04-19 2025-01-10 查美特制药公司 合成rig-i样受体激动剂
US12161710B2 (en) 2019-07-24 2024-12-10 Unm Rainforest Innovations Malaria immunogen and methods for using same
CA3155202A1 (en) 2019-10-23 2021-04-29 Arthur M. Krieg Synthetic rig-i-like receptor agonists
US12121574B2 (en) 2021-09-28 2024-10-22 Unm Rainforest Innovations Malaria immunogen and methods for using same
WO2024049946A1 (en) 2022-08-31 2024-03-07 Unm Rainforest Innovations Compositions targeting apoptosis-associated speck-like protein with caspase activation and recruitment domain (asc) and methods of use

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3160926D1 (en) * 1980-04-15 1983-10-27 Beecham Group Plc Allergens modified with polysarcosines
US4722840A (en) * 1984-09-12 1988-02-02 Chiron Corporation Hybrid particle immunogens
CA1319101C (en) 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
US5374426A (en) * 1986-09-03 1994-12-20 University Of Saskatchewan Rotavirus nucleocapsid protein VP6 in vaccine compositions
US5143726A (en) 1986-12-09 1992-09-01 The Scripps Research Institute T cell epitopes of the hepatitis B virus nucleocapsid protein
GB8903313D0 (en) * 1989-02-14 1989-04-05 Wellcome Found Conjugates
DE69018926T2 (de) 1989-09-04 1995-08-24 Wellcome Found Vakzine gegen Bordetella.
US5178882A (en) 1990-06-22 1993-01-12 The Regents Of The University Of California Viral decoy vaccine
US5334394A (en) * 1990-06-22 1994-08-02 The Regents Of The University Of California Human immunodeficiency virus decoy
SE9003978D0 (sv) * 1990-12-13 1990-12-13 Henrik Garoff Dna expressionssystem baserade paa ett virus replikon
AU9052091A (en) 1990-12-20 1992-07-22 Smithkline Beecham Biologicals (Sa) Vaccines based on hepatitis b surface antigen
CA2110899C (en) * 1991-06-21 2006-08-08 Jacob G. Michael Orally administrable therapeutic proteins and method of making
GB9114003D0 (en) * 1991-06-28 1991-08-14 Mastico Robert A Chimaeric protein
FR2695563B1 (fr) 1992-09-11 1994-12-02 Pasteur Institut Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires.
US6004763A (en) * 1992-09-11 1999-12-21 Institut Pasteur Antigen-carrying microparticles and their use in the induction of humoral or cellular responses
AU6172194A (en) * 1993-02-08 1994-08-29 Paravax, Inc. Defective sindbis virus vectors that express (toxoplasma gondii) p30 antigens
US6015686A (en) * 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
US6180771B1 (en) * 1993-12-08 2001-01-30 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor
AT402898B (de) 1994-08-08 1997-09-25 Int Centre Genetic Eng & Bio Molekulares präsentiersystem
CN1185811A (zh) 1995-03-31 1998-06-24 H·沃尔夫 依赖于逆转录病毒样颗粒的抗原呈递系统
US5792462A (en) * 1995-05-23 1998-08-11 University Of North Carolina At Chapel Hill Alphavirus RNA replicon systems
JPH09202735A (ja) * 1996-01-25 1997-08-05 Nof Corp リポソーム型アレルギー治療薬
KR100584051B1 (ko) 1996-03-01 2006-05-30 노파르티스 아게 알레르기에 대한 백신 접종 및 치료를 위한 펩티드임뮤노겐
US5786161A (en) * 1996-06-06 1998-07-28 Miltenyi Biotec. Gmbh Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity
US5770380A (en) * 1996-09-13 1998-06-23 University Of Pittsburgh Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
SE9604815D0 (sv) * 1996-12-20 1996-12-20 Pharmacia & Upjohn Ab A metod of diagnosis
ES2255181T3 (es) 1997-08-05 2006-06-16 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. Antigeno inmunoprotector contra la gripe y su uso en vacunacion.
DK1054689T3 (da) 1998-02-12 2004-01-26 Apovia Inc Strategisk modificerede hepatitis B-kerneproteiner og derivater deraf
TWI227241B (en) 1998-06-20 2005-02-01 United Biomedical Inc IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate
CA2347411C (en) * 1998-10-21 2012-04-03 The Government Of The United States Of America Virus-like particles for the induction of autoantibodies
KR100715954B1 (ko) * 1998-12-04 2007-05-09 바이오겐 아이덱 엠에이 인코포레이티드 펩티드 리간드에 의하여 부착된 다중 면역원성 성분을보유한 ｈｂｖ 코어 항원 입자
EP1278542A2 (en) * 2000-05-05 2003-01-29 Cytos Biotechnology AG Molecular antigen arrays and vaccines

Also Published As

Publication number Publication date
AU768807B2 (en) 2004-01-08
CN100534529C (zh) 2009-09-02
CN1679932A (zh) 2005-10-12
US20040136962A1 (en) 2004-07-15
JP2010510960A (ja) 2010-04-08
MXPA01005389A (es) 2003-03-27
PL192016B1 (pl) 2006-08-31
EP1135162B1 (en) 2008-10-29
BR9915771A (pt) 2001-12-26
RU2245163C2 (ru) 2005-01-27
ATE412434T1 (de) 2008-11-15
US7229624B2 (en) 2007-06-12
DE69939836D1 (de) 2008-12-11
IL143441A (en) 2006-10-31
WO2000032227A3 (en) 2000-10-12
DK1135162T3 (da) 2009-01-19
CN1193791C (zh) 2005-03-23
ES2317711T3 (es) 2009-04-16
NZ512456A (en) 2003-10-31
WO2000032227A2 (en) 2000-06-08
EP1135162A2 (en) 2001-09-26
PL348452A1 (en) 2002-05-20
AU1402000A (en) 2000-06-19
CA2354183A1 (en) 2000-06-08
CN1333693A (zh) 2002-01-30

Similar Documents

Publication Publication Date Title
IL143441A0 (en) Non-naturally occuring antigen arrays and processes for the preparation thereof
WO2001085208A3 (en) Molecular antigen arrays and vaccines
WO2004042001A3 (en) Virus-like particles, methods of preparation, and immonogenic compositions
EP1399183A4 (en) CHIMERAL ALPHAVIRUS REPLICANT PARTICLES
PL317234A1 (en) Vaccines against papilloma virus
BR0113577A (pt) Empacotamento de partìculas de replicon de vìrus de rna de filamento positivo
EP1820853A3 (en) Recombinant influenza viruses for vaccines and gene therapy
DE60234375D1 (de) VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
MX2007003171A (es) Particulas tipo virus que comprenden una proteina de fusion de la proteina de cubierta de ap205 y un polipeptido antigenico.
DE59611189D1 (de) Vp-antigene des jc-virus
AUPR011700A0 (en) Composition comprising immunogenic virus sized particles (VSP)
NZ503830A (en) Papilloma virus capsomere vaccine formulations and methods of use
ATE489969T1 (de) Verpackte virusartige partikel in kombination mit cpg zur verwendung als adjuvantien mit allergenen. herstellungsverfahren und verwendung
DE69934885D1 (de) Neue methoden und interferon defiziente substrate zur vermehrung von viren
WO2003039459A3 (en) Viral vector production methods and compositions
ZA956797B (en) Method for preparing influenza virus, antigens obtained and the applications.
MY150893A (en) Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines
AU2003250680A1 (en) Recombinant vesicular stomatitis virus vaccines for viral hemorrhagic fevers
AR004464A1 (es) Un metodo para producir una proteina de capside de papilomavirus
EP1749885B8 (en) Infectious and attenuated bovine viral diarrhea virus vaccine
MXPA02012593A (es) Particulas de tipo virus del virus de la diarrea viral bovina.
AU2002225509A1 (en) Production and of viruses, viral isolates and vaccines
ATE372129T1 (de) Impfstoff von umhüllten viren und verfahren zu seiner herstellung
CA2311336A1 (en) Enhanced immunogen for inactivated vaccine for infection with japanese encephalitis viruses and process for producing the same
HUP0101652A1 (hu) Új kompozíció

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed