IL143232A0 - Novel triazolo (4,5-d) pyrimidine compounds - Google Patents

Novel triazolo (4,5-d) pyrimidine compounds

Info

Publication number
IL143232A0
IL143232A0 IL14323299A IL14323299A IL143232A0 IL 143232 A0 IL143232 A0 IL 143232A0 IL 14323299 A IL14323299 A IL 14323299A IL 14323299 A IL14323299 A IL 14323299A IL 143232 A0 IL143232 A0 IL 143232A0
Authority
IL
Israel
Prior art keywords
pyrimidine compounds
novel triazolo
triazolo
novel
pyrimidine
Prior art date
Application number
IL14323299A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26663448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL143232(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE9804211A external-priority patent/SE9804211D0/xx
Priority claimed from SE9901271A external-priority patent/SE9901271D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IL143232A0 publication Critical patent/IL143232A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL14323299A 1998-12-04 1999-12-02 Novel triazolo (4,5-d) pyrimidine compounds IL143232A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9804211A SE9804211D0 (sv) 1998-12-04 1998-12-04 Novel compounds
SE9901271A SE9901271D0 (sv) 1999-04-09 1999-04-09 Novel compounds
PCT/SE1999/002256 WO2000034283A1 (en) 1998-12-04 1999-12-02 Novel triazolo(4,5-d)pyrimidine compounds

Publications (1)

Publication Number Publication Date
IL143232A0 true IL143232A0 (en) 2002-04-21

Family

ID=26663448

Family Applications (6)

Application Number Title Priority Date Filing Date
IL14323299A IL143232A0 (en) 1998-12-04 1999-12-02 Novel triazolo (4,5-d) pyrimidine compounds
IL143232A IL143232A (en) 1998-12-04 2001-05-17 5 - [7 - (2 - Phenylcyclopropyl) amino] - 5 - (Alkylthio) - 3H - 3,2,1 - Triazolo (5,4 – D) Pyrimidine - 3 - Il-Cyclopentane - 2,1 - Diols, their preparation , Pharmaceutical preparations containing them and a number of chemical intermediates for them
IL169013A IL169013A (en) 1998-12-04 2005-06-06 History of 2-Alkylthio-4-Cyclopentylamino-5-Amino-Pyrimidine as intermediates in the process of preparation of 3– [7– (2-phenylcyclopropyl) amino] –5– (Alkylthio) –3 h - [- [3,2,1 Triazolo [5, 4 – d] pyrimidine – 3 – il – cyclopentane – 2,1 – diols
IL183969A IL183969A (en) 1998-12-04 2007-06-14 Intermediates of 3 - (Transformed Cyclopentyl) - 3H - 3,2,1 - Triazolo (4,5 – D) Pyrimidine for antithrombotic compounds
IL198040A IL198040A (en) 1998-12-04 2009-04-06 Annotations 6α, 4α, 3aα, 6aα– Tetrahydro– h4– Cyclopenta – 3,1 – Dioxol
IL210398A IL210398A0 (en) 1998-12-04 2010-12-30 Novel triazolo (4, 5 - d) pyrimidine

Family Applications After (5)

Application Number Title Priority Date Filing Date
IL143232A IL143232A (en) 1998-12-04 2001-05-17 5 - [7 - (2 - Phenylcyclopropyl) amino] - 5 - (Alkylthio) - 3H - 3,2,1 - Triazolo (5,4 – D) Pyrimidine - 3 - Il-Cyclopentane - 2,1 - Diols, their preparation , Pharmaceutical preparations containing them and a number of chemical intermediates for them
IL169013A IL169013A (en) 1998-12-04 2005-06-06 History of 2-Alkylthio-4-Cyclopentylamino-5-Amino-Pyrimidine as intermediates in the process of preparation of 3– [7– (2-phenylcyclopropyl) amino] –5– (Alkylthio) –3 h - [- [3,2,1 Triazolo [5, 4 – d] pyrimidine – 3 – il – cyclopentane – 2,1 – diols
IL183969A IL183969A (en) 1998-12-04 2007-06-14 Intermediates of 3 - (Transformed Cyclopentyl) - 3H - 3,2,1 - Triazolo (4,5 – D) Pyrimidine for antithrombotic compounds
IL198040A IL198040A (en) 1998-12-04 2009-04-06 Annotations 6α, 4α, 3aα, 6aα– Tetrahydro– h4– Cyclopenta – 3,1 – Dioxol
IL210398A IL210398A0 (en) 1998-12-04 2010-12-30 Novel triazolo (4, 5 - d) pyrimidine

Country Status (36)

Country Link
US (12) USRE46276E1 (id)
EP (5) EP1386917B1 (id)
JP (4) JP4202607B2 (id)
KR (4) KR100776484B1 (id)
CN (1) CN1128801C (id)
AR (3) AR023920A1 (id)
AT (3) ATE418547T1 (id)
AU (1) AU766618B2 (id)
BR (1) BRPI9915883B8 (id)
CA (1) CA2351709C (id)
CY (3) CY1110501T1 (id)
CZ (3) CZ300373B6 (id)
DE (4) DE69915675D1 (id)
DK (3) DK1386921T3 (id)
EG (1) EG24814A (id)
ES (3) ES2216623T3 (id)
FR (1) FR11C0016I2 (id)
HK (3) HK1039933B (id)
HU (2) HU228589B1 (id)
ID (1) ID29927A (id)
IL (6) IL143232A0 (id)
LT (1) LTC1135391I2 (id)
LU (1) LU91819I2 (id)
MY (1) MY121867A (id)
NO (2) NO319806B1 (id)
NZ (1) NZ511778A (id)
PL (1) PL201283B1 (id)
PT (2) PT1135391E (id)
RU (3) RU2317990C2 (id)
SA (1) SA99200848B1 (id)
SI (3) SI1386921T1 (id)
SK (1) SK286007B6 (id)
TR (1) TR200101567T2 (id)
TW (1) TWI229674B (id)
WO (1) WO2000034283A1 (id)
ZA (1) ZA200104094B (id)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
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SE9903290D0 (sv) * 1999-09-15 1999-09-15 Astra Pharma Prod Novel compounds
SE9904129D0 (sv) 1999-11-15 1999-11-15 Astra Pharma Prod Novel compounds
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
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TWI391378B (zh) 2006-03-16 2013-04-01 Astellas Pharma Inc 喹啉酮衍生物或其製藥學上可被容許之鹽
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WO2008024044A1 (en) * 2006-08-21 2008-02-28 Astrazeneca Ab Compositions, suitable for oral administration, comprising a triazolo [4, 5] pyrimidin derivate
JP2010508350A (ja) 2006-10-31 2010-03-18 ヤンセン ファーマシューティカ エヌ．ベー． Ａｄｐｐ２ｙ１２レセプターアンタゴニストとしてのトリアゾロピリミジン誘導体
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