IL141786A0 - A pharmaceutical composition for treating diabetes containing an ap2 inhibitor - Google Patents

A pharmaceutical composition for treating diabetes containing an ap2 inhibitor

Info

Publication number
IL141786A0
IL141786A0 IL14178699A IL14178699A IL141786A0 IL 141786 A0 IL141786 A0 IL 141786A0 IL 14178699 A IL14178699 A IL 14178699A IL 14178699 A IL14178699 A IL 14178699A IL 141786 A0 IL141786 A0 IL 141786A0
Authority
IL
Israel
Prior art keywords
inhibitor
pharmaceutical composition
treating diabetes
diabetes containing
pravastatin
Prior art date
Application number
IL14178699A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22280975&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL141786(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL141786A0 publication Critical patent/IL141786A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL14178699A 1998-09-17 1999-09-13 A pharmaceutical composition for treating diabetes containing an ap2 inhibitor IL141786A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10067798P 1998-09-17 1998-09-17
PCT/US1999/020946 WO2000015229A1 (en) 1998-09-17 1999-09-13 METHOD FOR TREATING DIABETES EMPLOYING AN aP2 INHIBITOR AND COMBINATION

Publications (1)

Publication Number Publication Date
IL141786A0 true IL141786A0 (en) 2002-03-10

Family

ID=22280975

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14178699A IL141786A0 (en) 1998-09-17 1999-09-13 A pharmaceutical composition for treating diabetes containing an ap2 inhibitor
IL14178599A IL141785A0 (en) 1998-09-17 1999-09-13 A pharmaceutical composition containing an ap2 inhibitor

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL14178599A IL141785A0 (en) 1998-09-17 1999-09-13 A pharmaceutical composition containing an ap2 inhibitor

Country Status (30)

Country Link
US (1) US20020035064A1 (es)
EP (2) EP1113801A4 (es)
JP (2) JP2002524517A (es)
KR (2) KR20010075150A (es)
CN (2) CN1317970A (es)
AT (1) ATE406898T1 (es)
AU (2) AU755563B2 (es)
BG (2) BG105431A (es)
BR (2) BR9913831A (es)
CA (2) CA2344309A1 (es)
CO (2) CO5130025A1 (es)
CZ (2) CZ2001965A3 (es)
DE (1) DE69939481D1 (es)
EE (2) EE04356B1 (es)
ES (1) ES2311306T3 (es)
GE (2) GEP20033045B (es)
HU (2) HUP0104108A2 (es)
ID (2) ID28450A (es)
IL (2) IL141786A0 (es)
LT (2) LT4871B (es)
LV (2) LV12686B (es)
NO (2) NO20011351L (es)
NZ (2) NZ510207A (es)
PE (2) PE20001047A1 (es)
PL (2) PL346661A1 (es)
SK (1) SK3202001A3 (es)
TR (2) TR200100773T2 (es)
UY (2) UY25714A1 (es)
WO (2) WO2000015230A1 (es)
ZA (2) ZA200207433B (es)

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AU2005201289B2 (en) * 1999-02-12 2008-04-17 President And Fellows Of Harvard College Inhibiting formation of atherosclerotic lesions
WO2000047734A1 (en) * 1999-02-12 2000-08-17 President And Fellows Of Harvard College Inhibiting formation of atherosclerotic lesions
US6548529B1 (en) 1999-04-05 2003-04-15 Bristol-Myers Squibb Company Heterocyclic containing biphenyl aP2 inhibitors and method
US6586438B2 (en) 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
JP2004501066A (ja) 2000-01-28 2004-01-15 ブリストル−マイヤーズ　スクイブ　カンパニー 脂肪酸結合タンパク質のテトラヒドロピリミドンインヒビターおよび方法
US6670380B2 (en) 2000-11-20 2003-12-30 Bristol-Myers Squibb Co. Pyridone inhibitors of fatty acid binding protein and method
WO2002072146A2 (en) * 2001-03-12 2002-09-19 Novartis Ag Combination of nateglinide or repaglinide with at least one further antidiabetic compound
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EP1443919A4 (en) 2001-11-16 2006-03-22 Bristol Myers Squibb Co DOUBLE INHIBITORS OF THE FATTY ACID BINDING PROTEIN OF THE ADIPOCYTES AND THE FATTY ACID BINDING PROTEIN OF KERATINOCYTES
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JP6223376B2 (ja) * 2014-03-24 2017-11-01 花王株式会社 Ｇｉｐ上昇抑制剤の評価又は選択方法
BR112017023158A2 (pt) 2015-04-30 2018-07-24 Harvard College anticorpos anti-ap2 e agentes de ligação de antígeno para tratar distúrbios metabólicos
EA201990136A1 (ru) * 2016-06-27 2019-05-31 Президент Энд Феллоуз Оф Гарвард Колледж Соединения, применимые для лечения нарушений обмена веществ
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Also Published As

Publication number Publication date
EP1121129B1 (en) 2008-09-03
CZ2001964A3 (cs) 2002-01-16
GEP20033045B (en) 2003-08-25
CN1317970A (zh) 2001-10-17
ATE406898T1 (de) 2008-09-15
HUP0104240A2 (hu) 2002-03-28
LT4871B (lt) 2001-12-27
LV12686B (lv) 2001-10-20
EP1113801A1 (en) 2001-07-11
EP1113801A4 (en) 2002-10-02
BR9913833A (pt) 2001-05-29
UY25713A1 (es) 2001-08-27
CO5130025A1 (es) 2002-02-27
CN1319012A (zh) 2001-10-24
NO20011352L (no) 2001-05-11
EP1121129A1 (en) 2001-08-08
UY25714A1 (es) 2001-08-27
AU755563B2 (en) 2002-12-12
AU6143799A (en) 2000-04-03
LV12687A (en) 2001-07-20
KR20010079842A (ko) 2001-08-22
LT2001023A (en) 2001-08-27
IL141785A0 (en) 2002-03-10
PL346661A1 (en) 2002-02-25
CA2344300A1 (en) 2000-03-23
BG105431A (en) 2001-12-29
GEP20033044B (en) 2003-08-25
NO20011352D0 (no) 2001-03-16
ZA200207430B (en) 2003-09-16
PE20001047A1 (es) 2000-12-24
JP2002524517A (ja) 2002-08-06
WO2000015230A1 (en) 2000-03-23
CO5130026A1 (es) 2002-02-27
LV12687B (lv) 2001-10-20
NZ510207A (en) 2003-08-29
EE04356B1 (et) 2004-10-15
BR9913831A (pt) 2001-05-29
NO20011351L (no) 2001-05-11
TR200100773T2 (tr) 2001-07-23
JP2002524518A (ja) 2002-08-06
TR200100774T2 (tr) 2001-12-21
LV12686A (en) 2001-07-20
EE200100154A (et) 2002-12-16
CZ2001965A3 (cs) 2002-02-13
KR20010075150A (ko) 2001-08-09
CA2344309A1 (en) 2000-03-23
SK3202001A3 (en) 2002-04-04
ES2311306T3 (es) 2009-02-01
LT4870B (lt) 2001-12-27
HUP0104108A2 (hu) 2002-03-28
AU754488B2 (en) 2002-11-14
US20020035064A1 (en) 2002-03-21
ID27833A (id) 2001-04-26
EE200100155A (et) 2002-08-15
BG105432A (en) 2001-12-29
PE20001056A1 (es) 2000-12-24
WO2000015229A1 (en) 2000-03-23
PL346660A1 (en) 2002-02-25
DE69939481D1 (de) 2008-10-16
ID28450A (id) 2001-05-24
NO20011351D0 (no) 2001-03-16
AU6387799A (en) 2000-04-03
NZ510209A (en) 2003-07-25
LT2001022A (en) 2001-08-27
ZA200207433B (en) 2003-10-27
EP1121129A4 (en) 2002-10-16

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