ATE406898T1 - Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet - Google Patents

Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet

Info

Publication number
ATE406898T1
ATE406898T1 AT99951438T AT99951438T ATE406898T1 AT E406898 T1 ATE406898 T1 AT E406898T1 AT 99951438 T AT99951438 T AT 99951438T AT 99951438 T AT99951438 T AT 99951438T AT E406898 T1 ATE406898 T1 AT E406898T1
Authority
AT
Austria
Prior art keywords
inhibitor
treating diabetes
associated combinations
combinations
pravastatin
Prior art date
Application number
AT99951438T
Other languages
English (en)
Inventor
Jeffrey Robl
Rex PARKER
Scott Biller
Haris Jamil
Bruce Jacobson
Krishna Kodukula
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22280975&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE406898(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE406898T1 publication Critical patent/ATE406898T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT99951438T 1998-09-17 1999-09-13 Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet ATE406898T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10067798P 1998-09-17 1998-09-17

Publications (1)

Publication Number Publication Date
ATE406898T1 true ATE406898T1 (de) 2008-09-15

Family

ID=22280975

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99951438T ATE406898T1 (de) 1998-09-17 1999-09-13 Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet

Country Status (30)

Country Link
US (1) US20020035064A1 (de)
EP (2) EP1113801A4 (de)
JP (2) JP2002524518A (de)
KR (2) KR20010075150A (de)
CN (2) CN1317970A (de)
AT (1) ATE406898T1 (de)
AU (2) AU754488B2 (de)
BG (2) BG105431A (de)
BR (2) BR9913833A (de)
CA (2) CA2344300A1 (de)
CO (2) CO5130025A1 (de)
CZ (2) CZ2001965A3 (de)
DE (1) DE69939481D1 (de)
EE (2) EE200100155A (de)
ES (1) ES2311306T3 (de)
GE (2) GEP20033044B (de)
HU (2) HUP0104240A2 (de)
ID (2) ID27833A (de)
IL (2) IL141786A0 (de)
LT (2) LT4870B (de)
LV (2) LV12687B (de)
NO (2) NO20011352L (de)
NZ (2) NZ510209A (de)
PE (2) PE20001056A1 (de)
PL (2) PL346661A1 (de)
SK (1) SK3202001A3 (de)
TR (2) TR200100774T2 (de)
UY (2) UY25714A1 (de)
WO (2) WO2000015230A1 (de)
ZA (2) ZA200207433B (de)

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JP6223376B2 (ja) 2014-03-24 2017-11-01 花王株式会社 Ｇｉｐ上昇抑制剤の評価又は選択方法
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JP2018515082A (ja) 2015-04-30 2018-06-14 プレジデント アンド フェローズ オブ ハーバード カレッジ 代謝障害を処置するための抗ａｐ２抗体及び抗原結合剤
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Also Published As

Publication number Publication date
US20020035064A1 (en) 2002-03-21
PE20001047A1 (es) 2000-12-24
CN1319012A (zh) 2001-10-24
DE69939481D1 (de) 2008-10-16
WO2000015230A1 (en) 2000-03-23
LT2001023A (en) 2001-08-27
KR20010079842A (ko) 2001-08-22
LV12687B (lv) 2001-10-20
BG105431A (en) 2001-12-29
PE20001056A1 (es) 2000-12-24
AU755563B2 (en) 2002-12-12
UY25713A1 (es) 2001-08-27
NO20011351L (no) 2001-05-11
JP2002524517A (ja) 2002-08-06
SK3202001A3 (en) 2002-04-04
CA2344309A1 (en) 2000-03-23
NZ510207A (en) 2003-08-29
EP1113801A1 (de) 2001-07-11
IL141785A0 (en) 2002-03-10
BR9913833A (pt) 2001-05-29
GEP20033045B (en) 2003-08-25
UY25714A1 (es) 2001-08-27
ID28450A (id) 2001-05-24
EP1121129A1 (de) 2001-08-08
PL346660A1 (en) 2002-02-25
CO5130025A1 (es) 2002-02-27
ID27833A (id) 2001-04-26
IL141786A0 (en) 2002-03-10
WO2000015229A1 (en) 2000-03-23
EP1121129B1 (de) 2008-09-03
LV12686A (en) 2001-07-20
EE200100155A (et) 2002-08-15
NO20011352D0 (no) 2001-03-16
ES2311306T3 (es) 2009-02-01
CZ2001964A3 (cs) 2002-01-16
LT4871B (lt) 2001-12-27
LV12686B (lv) 2001-10-20
EE200100154A (et) 2002-12-16
ZA200207433B (en) 2003-10-27
AU754488B2 (en) 2002-11-14
EP1121129A4 (de) 2002-10-16
PL346661A1 (en) 2002-02-25
CN1317970A (zh) 2001-10-17
EE04356B1 (et) 2004-10-15
AU6387799A (en) 2000-04-03
ZA200207430B (en) 2003-09-16
BR9913831A (pt) 2001-05-29
CA2344300A1 (en) 2000-03-23
TR200100774T2 (tr) 2001-12-21
GEP20033044B (en) 2003-08-25
CZ2001965A3 (cs) 2002-02-13
LT4870B (lt) 2001-12-27
BG105432A (en) 2001-12-29
EP1113801A4 (de) 2002-10-02
NO20011351D0 (no) 2001-03-16
HUP0104108A2 (hu) 2002-03-28
TR200100773T2 (tr) 2001-07-23
NZ510209A (en) 2003-07-25
JP2002524518A (ja) 2002-08-06
CO5130026A1 (es) 2002-02-27
HUP0104240A2 (hu) 2002-03-28
KR20010075150A (ko) 2001-08-09
AU6143799A (en) 2000-04-03
LT2001022A (en) 2001-08-27
NO20011352L (no) 2001-05-11
LV12687A (en) 2001-07-20

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