IL136100A - Biphenylamidine derivatives and pharmaceutical compositions containing the same - Google Patents
Biphenylamidine derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL136100A IL136100A IL13610098A IL13610098A IL136100A IL 136100 A IL136100 A IL 136100A IL 13610098 A IL13610098 A IL 13610098A IL 13610098 A IL13610098 A IL 13610098A IL 136100 A IL136100 A IL 136100A
- Authority
- IL
- Israel
- Prior art keywords
- same
- pharmaceutical compositions
- compositions containing
- biphenylamidine derivatives
- biphenylamidine
- Prior art date
Links
- LNUYLGUBVHEHEL-UHFFFAOYSA-N 2-phenylbenzenecarboximidamide Chemical class NC(=N)C1=CC=CC=C1C1=CC=CC=C1 LNUYLGUBVHEHEL-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/18—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31969897 | 1997-11-20 | ||
| JP12749898 | 1998-05-11 | ||
| PCT/JP1998/005209 WO1999026918A1 (en) | 1997-11-20 | 1998-11-19 | Biphenylamidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL136100A0 IL136100A0 (en) | 2001-05-20 |
| IL136100A true IL136100A (en) | 2005-05-17 |
Family
ID=26463455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13610098A IL136100A (en) | 1997-11-20 | 1998-11-19 | Biphenylamidine derivatives and pharmaceutical compositions containing the same |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6706745B1 (de) |
| EP (1) | EP1043310B1 (de) |
| KR (1) | KR100581506B1 (de) |
| CN (1) | CN1150162C (de) |
| AT (1) | ATE268751T1 (de) |
| AU (1) | AU744567B2 (de) |
| BG (1) | BG63536B1 (de) |
| BR (1) | BR9814983A (de) |
| CA (1) | CA2310331A1 (de) |
| DE (1) | DE69824450T2 (de) |
| DK (1) | DK1043310T3 (de) |
| EE (1) | EE04564B1 (de) |
| ES (1) | ES2218866T3 (de) |
| HR (1) | HRP20000304B1 (de) |
| HU (1) | HUP0100085A3 (de) |
| ID (1) | ID24846A (de) |
| IL (1) | IL136100A (de) |
| IS (1) | IS5497A (de) |
| NO (1) | NO20002589L (de) |
| NZ (1) | NZ504407A (de) |
| PL (1) | PL340658A1 (de) |
| PT (1) | PT1043310E (de) |
| RU (1) | RU2197478C2 (de) |
| SK (1) | SK7612000A3 (de) |
| TR (1) | TR200001452T2 (de) |
| TW (1) | TW523504B (de) |
| UA (1) | UA52797C2 (de) |
| WO (1) | WO1999026918A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ504324A (en) * | 1997-11-20 | 2002-02-01 | Teijin Ltd | Biphenylamidine derivatives and pharmaceutical compositions thereof; which can be useful as anticoagulant inhibitors, and thrombus or embolus preventing agents |
| CA2360686A1 (en) * | 1999-01-28 | 2000-08-03 | Teijin Limited | Release-regulating preparations |
| HK1040510A1 (en) | 1999-05-17 | 2002-06-14 | Teijin Limited | Cyanobiphenyl derivatives |
| AU2001234689A1 (en) * | 2000-02-01 | 2001-08-14 | Cor Therapeutics, Inc. | Bivalent phenylene inhibitors of factor xa |
| PL206094B1 (pl) * | 2000-10-04 | 2010-06-30 | Kissei Pharmaceutical | Pochodne 5-amidyno-2- hydroksybenzenosulfonamidu, zawierająca je kompozycja farmaceutyczna oraz zastosowanie takiej pochodnej |
| US6316475B1 (en) * | 2000-11-17 | 2001-11-13 | Abbott Laboratories | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications |
| CN1610665A (zh) * | 2001-01-26 | 2005-04-27 | 帝人株式会社 | 氰基苯基苯甲酸衍生物的制备方法 |
| KR20030069226A (ko) * | 2001-01-29 | 2003-08-25 | 데이진 가부시키가이샤 | 벤즈아미딘 유도체 및 이의 제조 방법 |
| AR035425A1 (es) * | 2001-01-30 | 2004-05-26 | Teijin Ltd | Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo |
| JPWO2002060448A1 (ja) * | 2001-01-30 | 2004-05-27 | 帝人株式会社 | 医薬組成物 |
| JPWO2003040086A1 (ja) * | 2001-11-09 | 2005-03-03 | キッセイ薬品工業株式会社 | ５−アミジノ−２−ヒドロキシベンゼンスルホンアミド誘導体、それを含有する医薬組成物、その医薬用途およびその製造中間体 |
| CN1582272A (zh) | 2001-11-30 | 2005-02-16 | 帝人株式会社 | 制备5－(3－氰基苯基)－3－甲酰基苯甲酸化合物的方法 |
| WO2004050637A2 (en) | 2002-12-03 | 2004-06-17 | Axys Pharmaceuticals, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
| BRPI0512661B8 (pt) * | 2004-06-30 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivado de arilamidina ou um sal do mesmo, composto ou um sal do mesmo, e, composto antifúngico |
| KR20080034517A (ko) | 2005-08-18 | 2008-04-21 | 데이진 화-마 가부시키가이샤 | 정확한 용량 분할 기능을 갖는 제제 |
| CA2619745A1 (en) | 2005-08-18 | 2007-02-22 | Teijin Pharma Limited | Tablet with multiple drug-containing sections |
| PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
| EP3307725A1 (de) | 2015-06-11 | 2018-04-18 | Basilea Pharmaceutica International AG | Effluxpumpenhemmer und therapeutische verwendungen davon |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2550192B1 (fr) * | 1983-08-03 | 1986-04-04 | Sanofi Sa | Nouveaux derives de la benzamidine a activite antimicrobienne, leur procede de preparation, leur utilisation en tant que medicaments desinfectants ou conservateurs |
| DE4102024A1 (de) | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| ATE140225T1 (de) | 1992-04-28 | 1996-07-15 | Thomae Gmbh Dr K | Tritiumarkierte fibrinogen-rezeptor-antagonisten, deren verwendung und verfahren zur ihrer herstellung |
| DE4219158A1 (de) * | 1992-06-11 | 1993-12-16 | Thomae Gmbh Dr K | Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE19546452A1 (de) * | 1995-12-13 | 1997-06-19 | Boehringer Ingelheim Kg | Neue Phenylamidinderivate, Verfahren zu ihrer Herstelung und ihre Verwendung als Arzneimittel |
| JPH101467A (ja) * | 1996-06-13 | 1998-01-06 | Banyu Pharmaceut Co Ltd | ビフェニルアミジン誘導体 |
| DE19636689A1 (de) * | 1996-09-10 | 1998-03-12 | Boehringer Ingelheim Kg | Neue Benzamidinderivate |
| NZ504324A (en) | 1997-11-20 | 2002-02-01 | Teijin Ltd | Biphenylamidine derivatives and pharmaceutical compositions thereof; which can be useful as anticoagulant inhibitors, and thrombus or embolus preventing agents |
-
1998
- 1998-11-19 AT AT98954747T patent/ATE268751T1/de not_active IP Right Cessation
- 1998-11-19 CN CNB988132206A patent/CN1150162C/zh not_active Expired - Fee Related
- 1998-11-19 AU AU11740/99A patent/AU744567B2/en not_active Ceased
- 1998-11-19 TR TR2000/01452T patent/TR200001452T2/xx unknown
- 1998-11-19 PT PT98954747T patent/PT1043310E/pt unknown
- 1998-11-19 HU HU0100085A patent/HUP0100085A3/hu unknown
- 1998-11-19 US US09/554,799 patent/US6706745B1/en not_active Expired - Fee Related
- 1998-11-19 NZ NZ504407A patent/NZ504407A/en unknown
- 1998-11-19 KR KR1020007005463A patent/KR100581506B1/ko not_active Expired - Fee Related
- 1998-11-19 TW TW087119208A patent/TW523504B/zh not_active IP Right Cessation
- 1998-11-19 SK SK761-2000A patent/SK7612000A3/sk unknown
- 1998-11-19 ID IDW20000955A patent/ID24846A/id unknown
- 1998-11-19 CA CA002310331A patent/CA2310331A1/en not_active Abandoned
- 1998-11-19 PL PL98340658A patent/PL340658A1/xx not_active Application Discontinuation
- 1998-11-19 IL IL13610098A patent/IL136100A/xx not_active IP Right Cessation
- 1998-11-19 BR BR9814983-0A patent/BR9814983A/pt not_active Application Discontinuation
- 1998-11-19 EP EP98954747A patent/EP1043310B1/de not_active Expired - Lifetime
- 1998-11-19 RU RU2000115947/04A patent/RU2197478C2/ru not_active IP Right Cessation
- 1998-11-19 DK DK98954747T patent/DK1043310T3/da active
- 1998-11-19 WO PCT/JP1998/005209 patent/WO1999026918A1/ja not_active Ceased
- 1998-11-19 UA UA2000063535A patent/UA52797C2/uk unknown
- 1998-11-19 HR HR20000304A patent/HRP20000304B1/xx not_active IP Right Cessation
- 1998-11-19 ES ES98954747T patent/ES2218866T3/es not_active Expired - Lifetime
- 1998-11-19 EE EEP200000298A patent/EE04564B1/xx not_active IP Right Cessation
- 1998-11-19 DE DE69824450T patent/DE69824450T2/de not_active Expired - Fee Related
-
2000
- 2000-05-15 IS IS5497A patent/IS5497A/is unknown
- 2000-05-17 BG BG104447A patent/BG63536B1/bg unknown
- 2000-05-19 NO NO20002589A patent/NO20002589L/no unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |