IL135949A0 - Substituted porphyrins - Google Patents

Substituted porphyrins

Info

Publication number
IL135949A0
IL135949A0 IL13594998A IL13594998A IL135949A0 IL 135949 A0 IL135949 A0 IL 135949A0 IL 13594998 A IL13594998 A IL 13594998A IL 13594998 A IL13594998 A IL 13594998A IL 135949 A0 IL135949 A0 IL 135949A0
Authority
IL
Israel
Prior art keywords
substituted porphyrins
oxidants
relates
processes
modulating
Prior art date
Application number
IL13594998A
Other languages
English (en)
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Publication of IL135949A0 publication Critical patent/IL135949A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL13594998A 1997-11-03 1998-11-03 Substituted porphyrins IL135949A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6411697P 1997-11-03 1997-11-03
PCT/US1998/023287 WO1999023097A1 (fr) 1997-11-03 1998-11-03 Porphyrines substituees

Publications (1)

Publication Number Publication Date
IL135949A0 true IL135949A0 (en) 2001-05-20

Family

ID=22053669

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13594998A IL135949A0 (en) 1997-11-03 1998-11-03 Substituted porphyrins

Country Status (10)

Country Link
US (4) US6916799B2 (fr)
EP (1) EP1045851B1 (fr)
JP (2) JP2001521939A (fr)
AT (1) ATE238307T1 (fr)
AU (1) AU737650B2 (fr)
CA (1) CA2309154C (fr)
DE (1) DE69813898T2 (fr)
ES (1) ES2198767T3 (fr)
IL (1) IL135949A0 (fr)
WO (1) WO1999023097A1 (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
EP1045851B1 (fr) * 1997-11-03 2003-04-23 Duke University Porphyrines substituees
JP4648542B2 (ja) 1998-04-24 2011-03-09 デューク ユニバーシティ 置換ポルフィリン
WO2000023568A2 (fr) * 1998-10-06 2000-04-27 Albert Einstein College Of Medicine Of Yeshiva University Procedes et compositions permettant de reduire la surproduction de mitochondries des especes oxygene reactives dans les cellules
ES2385486T3 (es) 1999-01-25 2012-07-25 National Jewish Health Porfirinas sustituidas y su uso terapéutico
FR2806911B1 (fr) * 2000-03-28 2003-01-10 Univ Rene Descartes Utilisation de mimetiques de la sod dans le traitement d'insuffisances hepatocellulaires
DE60233317D1 (de) 2001-01-19 2009-09-24 Nat Jewish Med & Res Center Medikament zum schutz in der radiotherapie
US20040137638A1 (en) * 2002-03-04 2004-07-15 Slomczynska Urszula J. Chromatography of metal complexes
EP1439842A4 (fr) * 2001-06-01 2009-09-02 Nat Jewish Med & Res Center Capteurs oxydants destines au traitement du diabete ou a etre utilises dans une transplantation ou a induire une tolerance immunitaire
KR100951606B1 (ko) * 2001-12-14 2010-04-09 알콘 인코포레이티드 안과 질환 및 질병의 치료를 위한 과산화물 디스뮤타제모방체
EP1513537A4 (fr) * 2002-06-07 2006-09-06 Univ Duke Porphyrines substituees
EP1581212A4 (fr) * 2002-12-06 2008-11-05 Alcon Inc Analogues de dismutase de superoxyde destines au traitement de troubles et maladies oculaires
MXPA05005937A (es) * 2002-12-06 2005-08-18 Alcon Inc Imitaciones de superoxido de dismutasa para el tratamiento de trastornos y enfermedades oculares.
GB2397067B (en) * 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
NL1022597C2 (nl) * 2003-02-05 2004-08-06 Photobiochem N V Toepassing van een fotosensitizerverbinding voor de bereiding van een farmaceutisch preparaat, werkwijze voor het bereiden van een farmaceutisch preparaat en een werkwijze voor het behandelen van een zoogdier.
JP4741205B2 (ja) * 2003-07-07 2011-08-03 真 湯浅 金属ポルフィリン錯体包埋リポソーム、その製造方法およびこれを利用する医薬
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US8165651B2 (en) * 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
EP1718201B1 (fr) 2004-02-09 2016-09-14 Duke University Porphyrines substituees
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
EA010834B1 (ru) * 2004-03-29 2008-12-30 Инотек Фармасьютикалз Корпорейшн Пиридилзамещённые порфириновые соединения и способы их применения
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
EP1928467A4 (fr) * 2005-09-28 2009-11-04 Inotek Pharmaceuticals Corp Composes de pyridyle porphyrine a substitution n-benzyle et leurs procedes d'utilisation
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
EP3527079A1 (fr) 2006-10-12 2019-08-21 Galera Labs, LLC Procédés de traitement de la mucosite orale
US20080289053A1 (en) * 2007-05-15 2008-11-20 The Regents Of The University Of California Methods and systems for identifying modulators of longevity
US8598150B1 (en) 2008-04-02 2013-12-03 Jonathan R. Brestoff Composition and method for affecting obesity and related conditions
US8987245B2 (en) 2008-04-02 2015-03-24 Jonathan R. Brestoff Parker Composition and method for affecting obesity and related conditions
KR101646066B1 (ko) * 2008-05-23 2016-08-05 내셔날 쥬이쉬 헬스 알킬화 종으로의 노출과 관련된 상해를 치료하는 방법
US8608950B2 (en) * 2009-12-30 2013-12-17 Uop Llc Process for removing metals from resid
DK2625180T3 (en) * 2010-10-06 2016-06-06 Aeolus Sciences Inc Porphyrinbehandling neurodegenerative diseases
JP5823988B2 (ja) * 2011-01-31 2015-11-25 国立大学法人宇都宮大学 ポルフィリン型骨格を有する化合物の金属錯体の製造方法
CA2849456C (fr) 2011-09-26 2021-12-07 Galera Therapeutics, Llc Methodes de traitement de maladies
AU2012371568B2 (en) 2011-12-02 2017-06-08 The Regents Of The University Of Colorado, A Body Corporate Metalloporphyrin neurological treatments
US9999627B2 (en) 2013-09-03 2018-06-19 BioMimetix, JV, LLC Methods of treating erectile dysfunction
WO2015102745A1 (fr) 2013-12-31 2015-07-09 Abbott Diabetes Care Inc. Capteur d'analytes auto-alimenté et dispositifs utilisant ce dernier
US10064871B2 (en) 2014-01-22 2018-09-04 Biomimetix Jv, Llc Methods of treating skin disorders
US10080759B2 (en) 2014-01-22 2018-09-25 Duke University Methods of treating pruritus
AU2016306568B2 (en) 2015-08-11 2021-01-07 Galera Labs, Llc Pentaaza macrocyclic ring complexes possessing oral bioavailability
US11246950B2 (en) 2017-04-13 2022-02-15 Galera Labs, Llc Combination cancer immunotherapy with pentaaza macrocyclic ring complex
WO2018237249A1 (fr) * 2017-06-22 2018-12-27 Biomimetix Jv, Llc Méthodes, compositions et kits pour traiter et prévenir des affections cutanées inflammatoires
US11918549B2 (en) 2017-08-25 2024-03-05 AZ Solutions LLC System and method for wound treatment and irrigation
EP3687551A4 (fr) 2017-09-29 2021-06-23 Duke University Composés de porphyrine fluorosubstitué, compositions les comprenant et procédés de préparation et d'utilisation associés
CN111100133B (zh) * 2019-12-30 2020-12-01 云南大学 一种金属卟啉化合物及其制法和应用
WO2022235781A1 (fr) * 2021-05-04 2022-11-10 AZ solutions, LLC Traitement de maladies et de troubles pulmonaires et respiratoires

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2951799A (en) 1957-11-13 1960-09-06 Monsanto Chemicals Photoxidation processes using heterocyclic photosensitizers
DE3464252D1 (en) 1983-06-03 1987-07-23 Hoffmann La Roche Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation
US4829984A (en) 1983-12-15 1989-05-16 Gordon Robert T Method for the improvement of transplantation techniques and for the preservation of tissue
US4963367A (en) 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US5087438A (en) 1984-07-03 1992-02-11 Gordon Robert T Method for affecting intracellular and extracellular electric and magnetic dipoles
GB8429845D0 (en) 1984-11-26 1985-01-03 Efamol Ltd Porphyrins & cancer treatment
US4758422A (en) 1985-01-04 1988-07-19 Salutar Inc. Ferrioxamine paramagnetic contrast agents for MR imaging
US4657902A (en) 1985-03-25 1987-04-14 The Rockefeller University Therapeutic use of tin mesoporphyrin
WO1986006959A1 (fr) 1985-05-22 1986-12-04 Liposome Technology, Inc. Procede et systeme d'inhalation de liposomes
US5248603A (en) 1985-09-03 1993-09-28 Symbicom Aktiebolag Superoxide dismutase
DK402785D0 (da) 1985-09-03 1985-09-03 Syn Tek Ab Fremgangsmaade til fremstilling af et enzym
US4866054A (en) 1986-05-13 1989-09-12 Chai-Tech Corporation Antioxidant metallo-organic treatment of inflammation
US4746735A (en) 1986-11-21 1988-05-24 The Dow Chemical Company Regiospecific aryl nitration of meso-substituted tetraarylporphyrins
US5162231A (en) 1989-10-25 1992-11-10 Cole Dean A Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung
EP0676472A1 (fr) 1987-03-14 1995-10-11 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Manganèse-superoxyde dismutase humaine (hMn-SOD)
US5223538A (en) 1987-03-31 1993-06-29 Duke University Superoxide dismutase mimic
US5227405A (en) 1987-03-31 1993-07-13 Duke University Superoxide dismutase mimic
US4892941A (en) 1987-04-17 1990-01-09 Dolphin David H Porphyrins
US4851403A (en) 1987-04-21 1989-07-25 Johnson Matthey, Inc. Radiation sensitizers
US4885114A (en) 1987-04-22 1989-12-05 Barnes Engineering Co. Metallized tetra((meso)-5-methyl-2-thiophene)porphines, platinum (5-bromo octaethylporphine) and optical filters containing same
US5051337A (en) 1987-06-10 1991-09-24 Director-General Of Agency Of Industrial Science And Technology Optical recording material
GB8805849D0 (en) 1988-03-11 1988-04-13 Efamol Holdings Porphyrins & cancer treatment
US5162519A (en) 1988-03-11 1992-11-10 Efamol Holdings Plc Porphyrins and cancer treatment
US5284647A (en) 1988-03-18 1994-02-08 Schering Aktiengesellschaft Mesotetraphenylporphyrin complex compounds, process for their production and pharmaceutical agents containing them
DE3809671A1 (de) 1988-03-18 1989-09-28 Schering Ag Porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5192788A (en) 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
US5109016A (en) 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
FR2632187B1 (fr) 1988-06-02 1990-09-14 Centre Nat Rech Scient Derives de metalloporphyrines, leur preparation, leur application en therapeutique et leur utilisation pour la preparation de molecules hybrides
US5171680A (en) 1988-06-14 1992-12-15 Chiron Corporation Superoxide dismutase analogs having novel binding properties
EP0414915B1 (fr) 1989-03-06 1996-06-12 Suntory Limited Nouvelle superoxyde dismutase
JPH0341441A (ja) * 1989-07-07 1991-02-21 Konica Corp スポット故障の改良されたハロゲン化銀写真感光材料
DK455789D0 (da) 1989-09-15 1989-09-15 Symbicom Ab Polypeptid
US5010073A (en) 1989-10-05 1991-04-23 The Rockefeller University Use of liposomes as carriers for metalloporphyrins
EP0424033A3 (en) 1989-10-19 1991-07-31 Pola Chemical Industries Inc External skin preparation
US5236915A (en) 1990-05-31 1993-08-17 Health Research, Inc. Meso poly(4-sulfonatophenyl) porphines as MRI image enhancing agents
EP0462836A3 (en) 1990-06-20 1992-08-26 Mitsui Toatsu Chemicals, Inc. Recombinant vector plasmid capable of expressing human manganese superoxide dismutase, and process of producing this enzyme
US5202317A (en) 1990-09-13 1993-04-13 The Regents Of The University Of California Synthetic drug molecules that mimic metalloenzymes
US5217966A (en) 1990-09-13 1993-06-08 The Regents Of The University Of California Synthetic drug molecules that mimic metalloenzymes
WO1992007935A1 (fr) 1990-11-01 1992-05-14 The Scripps Research Institute Proteines de fusion ciblees par clycosaminoglycane, leurs conception, construction et compositions
JPH06504041A (ja) 1990-11-14 1994-05-12 ユー・エー・ビー・リサーチ　ファウンデーション 虚血性傷害を減少させる方法と組成
US5192757A (en) 1990-12-20 1993-03-09 Glaxo Inc. Cobalt porphyrins
GB9103991D0 (en) 1991-02-26 1991-04-10 Nat Res Dev Molecular electronic devices
FR2676738B1 (fr) 1991-05-22 1995-05-05 Ir2M Nouveau derive organique de metal de transition a structure porphyrinique, composition therapeutique le contenant, en particulier a activite hypoglycemiante.
KR0145953B1 (ko) 1991-07-19 1998-08-17 제임스 클리프튼 보올딩 슈퍼옥사이드의 불균화촉매로서 효과적인 질소를 포함하는 마크로사이클 릭리간드의 망간착물
CA2072934C (fr) 1991-07-19 2007-08-28 Karl William Aston Complexes de manganese et de ligands macrocycliques contenant de l'azote, efficaces comme catalyseurs de la dismutation de superoxydes
US5262532A (en) 1991-07-22 1993-11-16 E.R. Squibb & Sons, Inc. Paramagnetic metalloporphyrins as contrast agents for magnetic resonance imaging
US5212300A (en) 1991-09-12 1993-05-18 Sun Company, Inc. (R&M) Cyano- and polycyanometallo-porphyrins as catalysts for alkane oxidation
US6011146A (en) 1991-11-15 2000-01-04 Institut Pasteur Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
US5599924A (en) 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
US5493017A (en) 1992-08-14 1996-02-20 The Trustees Of The University Of Pennsylvania Ring-metalated porphyrins
US5371199B1 (en) 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
ATE201595T1 (de) 1992-09-03 2001-06-15 Univ California Metallporphyrinzusammensetzungen
US5696109A (en) 1992-12-07 1997-12-09 Eukarion, Inc. Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
US5403834A (en) 1992-12-07 1995-04-04 Eukarion, Inc. Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
US5834509A (en) 1992-12-07 1998-11-10 Eukarion, Inc. Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
US6204259B1 (en) 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
DE4305523A1 (de) 1993-02-17 1994-08-18 Diagnostikforschung Inst Meso-Tetraphenylporphyrin-Komplexverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US6417182B1 (en) 1993-08-25 2002-07-09 Anormed Inc. Pharmaceutical compositions comprising metal complexes
US5994339A (en) 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
US5608054A (en) 1993-12-29 1997-03-04 Sun Company, Inc. (R&M) Porphyrins and metal complexes thereof having haloalkyl side chains
US5405369A (en) 1994-01-25 1995-04-11 Medical College Of Ohio Photochemical ablation of gastro-intestinal tissue for augmentation of an organ
US5604199A (en) 1994-03-29 1997-02-18 The Nemours Foundation Method of treating fibrosis in skeletal muscle tissue
HUT76327A (en) 1994-05-13 1997-08-28 Monsanto Co Pharmaceutical compositions catalyzing decomposition of peroxy-nitrite
US6245758B1 (en) 1994-05-13 2001-06-12 Michael K. Stern Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor
US5563132A (en) 1994-06-21 1996-10-08 Bodaness; Richard S. Two-step cancer treatment method
FR2723694B1 (fr) * 1994-08-19 1996-09-27 Oreal Utilisation de sels de derives cationiques de porphine comme agents photosensibilisants de bacteries de type gram-negatif
WO1996009053A1 (fr) 1994-09-20 1996-03-28 Duke University Activite d'oxydoreductase de porphyrines manganiques
CA2132690A1 (fr) 1994-09-22 1996-03-23 Dean Willis Controle et modulation de la reponse inflammatoire chez les sujets qui en ont besoin
US6013241A (en) 1995-01-23 2000-01-11 Schering Aktiengesellschaft Use of porphyrin-complex or expanded porphyrin-complex compounds as an infarction localization diagnosticum
DE69635304T2 (de) * 1995-06-07 2006-07-20 Duke University Faenger fuer oxidantien
EP0844889A1 (fr) 1995-08-17 1998-06-03 Monsanto Company Methodes d'analyse d'images diagnostiques par conjugues biologique de complexes metalliques de ligands macrocycliques renfermant de l'azote
US5648523A (en) 1995-10-26 1997-07-15 Chiang Long Y Fullerene derivatives as free-radical scavengers
US5948771A (en) 1996-01-31 1999-09-07 The Trustees Of Columbia University In The City Of New York Method for treating heart failure using tetrapyrroles and metallotetrapyrroles
US5756492A (en) 1996-09-09 1998-05-26 Sangstat Medical Corporation Graft survival prolongation with porphyrins
EP0988037A1 (fr) * 1997-02-05 2000-03-29 Board Of Regents, The University Of Texas System Composes de porphyrine utilises comme inhibiteurs de telomerase
US6180620B1 (en) 1997-06-20 2001-01-30 G.D. Searle & Co. Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals
US6214817B1 (en) 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity
EP1045851B1 (fr) * 1997-11-03 2003-04-23 Duke University Porphyrines substituees
ES2385486T3 (es) 1999-01-25 2012-07-25 National Jewish Health Porfirinas sustituidas y su uso terapéutico
US6608050B2 (en) 1999-07-20 2003-08-19 Pharmacia & Upjohn Company Lyophilizate of lipid complex of water insoluble porphyrins
AU1087401A (en) 1999-10-13 2001-04-23 Uab Research Foundation Metalloporphyrin treatment of neurologic disease
WO2001040233A1 (fr) 1999-11-30 2001-06-07 Photochemical Co., Ltd. Complexe porphyrine servant de support a un nitroimidazole
JP3383839B2 (ja) 2000-03-13 2003-03-10 奈良先端科学技術大学院大学長 新規なメルカプト置換イミダゾリルポルフィリン金属錯体単量体及びこれを繰り返し単位として有する重合体並びにこれらの製造方法
US6624187B1 (en) 2000-06-12 2003-09-23 Health Research, Inc. Long wave length absorbing bacteriochlorin alkyl ether analogs
US6403788B1 (en) 2000-07-11 2002-06-11 Eukarion, Inc. Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species
US6573258B2 (en) * 2000-09-27 2003-06-03 Frontier Scientific, Inc. Photodynamic porphyrin antimicrobial agents
US6566517B2 (en) 2001-06-06 2003-05-20 Brookhaven Science Associates, Llc Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy

Also Published As

Publication number Publication date
ATE238307T1 (de) 2003-05-15
JP5312404B2 (ja) 2013-10-09
EP1045851A4 (fr) 2001-05-09
DE69813898D1 (de) 2003-05-28
US6916799B2 (en) 2005-07-12
US20020042407A1 (en) 2002-04-11
US20080113956A1 (en) 2008-05-15
JP2010229145A (ja) 2010-10-14
EP1045851A1 (fr) 2000-10-25
CA2309154C (fr) 2010-02-16
ES2198767T3 (es) 2004-02-01
DE69813898T2 (de) 2004-03-11
CA2309154A1 (fr) 1999-05-14
US20060074062A1 (en) 2006-04-06
US20070179124A1 (en) 2007-08-02
WO1999023097A1 (fr) 1999-05-14
AU1297999A (en) 1999-05-24
AU737650B2 (en) 2001-08-23
JP2001521939A (ja) 2001-11-13
EP1045851B1 (fr) 2003-04-23

Similar Documents

Publication Publication Date Title
IL135949A0 (en) Substituted porphyrins
MXPA01007451A (es) Porfirinas sustituidas.
EP1071474A4 (fr) Porphyrines substituees
MX9700557A (es) Dihidrobenzofuranos.
AU5624699A (en) Use of 5ht-6 antagonists
IL122451A0 (en) Oxidant scavengers
PL332432A1 (en) Oxadiazoles, method of obtaining them as well as their application as therapeutic agents
AP2001002225A0 (en) 1-heterocycle substituted diarylamines.
CY2538B1 (en) Tetrahydropyrido compounds
PL344475A1 (en) Bridged indenopyrrolocarbazoles
MX9804588A (es) Uso de composiciones que comprenden blanqueador de halogeno para suavidad mejorada a la piel.
ZA986363B (en) Novel method of treatment.
EP1019092A4 (fr) Outils therapeutiques et diagnostiques pour desordres lies a une mauvaise tolerance glucidique
ZA986364B (en) Novel method of treatment.
ZA986365B (en) Novel method of treatment.
ZA200007396B (en) Method of treatment.
AP2005003432A0 (en) Novel method of treatment.
ZA985235B (en) Novel method of treatment.
MY127539A (en) Bridged indenopyrrolocarbazoles
YU47301A (sh) Diarilamini sa supstituisanim 1-heterociklom

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired