IL134046A0 - Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide - Google Patents

Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide

Info

Publication number
IL134046A0
IL134046A0 IL13404698A IL13404698A IL134046A0 IL 134046 A0 IL134046 A0 IL 134046A0 IL 13404698 A IL13404698 A IL 13404698A IL 13404698 A IL13404698 A IL 13404698A IL 134046 A0 IL134046 A0 IL 134046A0
Authority
IL
Israel
Prior art keywords
diguanide
thiazolidinedione
diabetes
treatment
insulin secretagogue
Prior art date
Application number
IL13404698A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL134046A0 publication Critical patent/IL134046A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13404698A 1997-07-18 1998-07-16 Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide IL134046A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9715295A GB9715295D0 (en) 1997-07-18 1997-07-18 Novel method of treatment
PCT/GB1998/002110 WO1999003477A1 (en) 1997-07-18 1998-07-16 Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide

Publications (1)

Publication Number Publication Date
IL134046A0 true IL134046A0 (en) 2001-04-30

Family

ID=10816167

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13404698A IL134046A0 (en) 1997-07-18 1998-07-16 Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide

Country Status (39)

Country Link
EP (1) EP1001783B1 (forum.php)
JP (2) JP2001510159A (forum.php)
KR (1) KR100671918B1 (forum.php)
CN (1) CN1264303A (forum.php)
AP (1) AP1352A (forum.php)
AR (1) AR016349A1 (forum.php)
AT (1) ATE305790T1 (forum.php)
AU (1) AU8448898A (forum.php)
BG (1) BG64785B1 (forum.php)
BR (1) BR9810445A (forum.php)
CA (1) CA2296653C (forum.php)
CO (1) CO4940420A1 (forum.php)
CY (1) CY1105254T1 (forum.php)
DE (1) DE69831808T2 (forum.php)
DK (1) DK1001783T3 (forum.php)
DZ (1) DZ2562A1 (forum.php)
EA (1) EA003021B1 (forum.php)
ES (1) ES2251093T3 (forum.php)
GB (1) GB9715295D0 (forum.php)
HU (1) HUP0003629A3 (forum.php)
ID (1) ID24211A (forum.php)
IL (1) IL134046A0 (forum.php)
IN (1) IN189275B (forum.php)
MA (1) MA24607A1 (forum.php)
MY (1) MY155219A (forum.php)
NO (1) NO325727B1 (forum.php)
NZ (2) NZ501164A (forum.php)
OA (1) OA11279A (forum.php)
PE (1) PE99599A1 (forum.php)
PL (2) PL198017B1 (forum.php)
SA (1) SA98190468B1 (forum.php)
SI (1) SI1001783T1 (forum.php)
SK (1) SK285484B6 (forum.php)
TR (1) TR200000134T2 (forum.php)
TW (1) TW505516B (forum.php)
UA (1) UA70303C2 (forum.php)
UY (1) UY25102A1 (forum.php)
WO (1) WO1999003477A1 (forum.php)
ZA (1) ZA986363B (forum.php)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
CZ20011629A3 (cs) * 1998-11-12 2001-12-12 Smithkline Beecham Plc Farmaceutický prostředek pro upravené uvolňování senzitizéru inzulínu a jiných antidiabetických přípravků
SE9902918D0 (sv) * 1999-08-13 1999-08-13 Pharmacia & Upjohn Ab Methods for identification of compounds stimulating insulin secretion
JP2003514011A (ja) * 1999-11-16 2003-04-15 スミスクライン ビーチャム パブリック リミテッド カンパニー チアゾリジンジオン−塩酸メトホルミンを含む医薬組成物
MY125516A (en) * 1999-11-16 2006-08-30 Smithkline Beecham Plc Novel composition based on thiazolidinedione and metformin and use
FR2812547B1 (fr) * 2000-08-04 2002-10-31 Lipha Composition pharmaceutique comprenant une association metformine et derive de thiazolidinedione et son utilisation pour la preparation de medicaments destines a traiter le diabete
WO2002055009A1 (en) 2001-01-12 2002-07-18 Sun Pharmaceutical Industries Limited Spaced drug delivery system
ITFI20010126A1 (it) * 2001-07-09 2003-01-09 Molteni & C Composizioni farmaceutiche per uso orale,contenenti,in combinazione,metformina e gliclazide
EP1429747A4 (en) * 2001-07-10 2005-01-05 Kos Life Sciences Inc CORE FORMULATION WITH PIOGLITAZONE HYDROCHLORIDE AND A BIGUANIDE
AU2002356419A1 (en) 2002-06-17 2003-12-31 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
CA2499597C (en) * 2002-09-20 2012-01-17 Unchalee Kositprapa Multistage formulation containing a biguanide and thiazolidindione derivatives
UA80991C2 (en) 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
PT1677792E (pt) 2003-10-31 2016-02-09 Takeda Pharmaceutical Preparação sólida compreendendo pioglitazona, glimepirida e um éster de ácido gordo de polioxietileno sorbitano
MXPA05010977A (es) * 2005-10-12 2007-04-11 Abdala Leopoldo Espinosa Composiciones farmaceuticas que comprenden sustancias antidiabeticas combinadas para su uso en diabetes mellitus.
KR100812538B1 (ko) * 2006-10-23 2008-03-11 한올제약주식회사 약물 제어방출형 메트포르민-글리메피리드 복합제제
CN101417130B (zh) * 2007-10-22 2010-10-06 鲁南制药集团股份有限公司 一种治疗ⅱ型糖尿病及其并发症的药物组合物
CN111246859B (zh) * 2017-10-20 2022-05-03 诺麦塔制药有限公司 含有锌盐、环二肽-组氨酸脯氨酸及作为有效成分的抗糖尿药物的糖尿病预防或治疗用药学组合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) * 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US4582839A (en) * 1984-03-21 1986-04-15 Takeda Chemical Industries, Ltd. 2,4-thiazolidinediones
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
US4791125A (en) * 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
FI904414A0 (fi) * 1988-03-08 1990-09-07 Pfizer Tiazolidindion-hypoglykemiskt verkande aemnen.
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
JPH04210683A (ja) * 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−2,4−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
DE69219136T2 (de) * 1991-08-26 1997-08-28 Pharmacia & Upjohn Co., Kalamazoo, Mich. Flüssiges nahrungsmittel, das 3-guanidinopropionsäure enthält
US5917052A (en) * 1994-09-28 1999-06-29 Shaman Pharmaceuticals, Inc. Hypoglycemic agent from cryptolepis
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
KR20010013840A (ko) * 1997-06-18 2001-02-26 피터 기딩스 티아졸리딘디온 및 술포닐우레아를 사용한 당뇨병의 치료

Also Published As

Publication number Publication date
KR20010021947A (ko) 2001-03-15
AU8448898A (en) 1999-02-10
IN189275B (forum.php) 2003-01-25
TW505516B (en) 2002-10-11
DK1001783T3 (da) 2006-02-06
PL338126A1 (en) 2000-09-25
HK1028550A1 (en) 2001-02-23
ES2251093T3 (es) 2006-04-16
AR016349A1 (es) 2001-07-04
EA003021B1 (ru) 2002-12-26
KR100671918B1 (ko) 2007-01-22
TR200000134T2 (tr) 2000-09-21
UY25102A1 (es) 2000-12-29
OA11279A (en) 2003-07-31
MY155219A (en) 2015-09-30
NO20000228L (no) 2000-01-17
ID24211A (id) 2000-07-13
ATE305790T1 (de) 2005-10-15
NZ511608A (en) 2002-12-20
PL198017B1 (pl) 2008-05-30
DZ2562A1 (fr) 2003-02-15
SK592000A3 (en) 2000-09-12
HUP0003629A3 (en) 2003-04-28
SK285484B6 (sk) 2007-02-01
JP2001510159A (ja) 2001-07-31
AP2000001733A0 (en) 2000-03-31
JP2005213273A (ja) 2005-08-11
UA70303C2 (uk) 2004-10-15
HUP0003629A2 (hu) 2001-07-30
BG64785B1 (bg) 2006-04-28
BG104135A (en) 2000-10-31
NZ501164A (en) 2001-06-29
PE99599A1 (es) 1999-12-18
BR9810445A (pt) 2000-09-05
CA2296653C (en) 2007-10-02
NO325727B1 (no) 2008-07-07
MA24607A1 (fr) 1999-04-01
EP1001783A1 (en) 2000-05-24
EP1001783B1 (en) 2005-10-05
DE69831808D1 (de) 2006-02-16
CN1264303A (zh) 2000-08-23
PL197844B1 (pl) 2008-05-30
SI1001783T1 (sl) 2006-02-28
CO4940420A1 (es) 2000-07-24
CA2296653A1 (en) 1999-01-28
CY1105254T1 (el) 2010-03-03
AP1352A (en) 2004-12-24
ZA986363B (en) 2000-01-17
SA98190468B1 (ar) 2007-01-20
WO1999003477A1 (en) 1999-01-28
EA200000139A1 (ru) 2000-06-26
DE69831808T2 (de) 2006-07-06
NO20000228D0 (no) 2000-01-17
GB9715295D0 (en) 1997-09-24

Similar Documents

Publication Publication Date Title
AP9901719A0 (en) Treatment of diabetes with thiazolidinedione and metormin
IL134046A0 (en) Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide
PL342517A1 (en) Methods of treating diabetes employing peptidic insulin analoques
ZA985546B (en) Treatment of insulin resistance.
PL343123A1 (en) Treatment of diabetes with rosiglitazone and insulin
IL133907A0 (en) Treatment of diabetes with thiazolidinedione, insulin secretagogue and alpha glucocidase inhibitor
AP2000001734A0 (en) Treatment of diabetes with thiazolidinedione and sulphonylurea
AP9901717A0 (en) Treatment of diabetes with thiazolidinedione and sulphonylurea
EP0954324A4 (en) CYCLIC PEPTID VACCINES FOR DIABETES TREATMENT AND PREVENTION
IL133138A0 (en) Treatment of diabetes with thiazolidinedione and alpha-glucosidase inhibitor
HK1028551A (en) Treatment of diabetes with thiazolidinedione, insulin secretagogue and alpha glucosidase inhibitor
HUP0002668A3 (en) Treatment of diabetes with thiazolidinedione and metformin
HK1028198A (en) Treatment of diabetes with rosiglitazone and insulin
IL143088A0 (en) A method for the treatment of type 2 diabetes mellitus and conditions associated therewith, and a pharmaceutical composition comprising an insulin sensitiser for use in such a method
HUP0002669A3 (en) Treatment of diabetes with thiazolidinedione and sulphonylurea
IL94241A0 (en) Diagnosis and treatment of insulin dependent diabetes mellitus
AU8884198A (en) Diagnosis, prevention and treatment of diabetes
IL119526A0 (en) Preparations comprising T cells for prevention or treatment of insulin dependent diabetes mellitus (IDDM)
GB9609897D0 (en) Treatment of diabetes