IL133792A0 - Preparation of oxymorphone, oxycodone and derivatives - Google Patents

Preparation of oxymorphone, oxycodone and derivatives

Info

Publication number
IL133792A0
IL133792A0 IL13379298A IL13379298A IL133792A0 IL 133792 A0 IL133792 A0 IL 133792A0 IL 13379298 A IL13379298 A IL 13379298A IL 13379298 A IL13379298 A IL 13379298A IL 133792 A0 IL133792 A0 IL 133792A0
Authority
IL
Israel
Prior art keywords
synthesis
oxymorphone
oxycodone
derivatives
preparation
Prior art date
Application number
IL13379298A
Other languages
English (en)
Original Assignee
Penick Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25401603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL133792(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Penick Corp filed Critical Penick Corp
Publication of IL133792A0 publication Critical patent/IL133792A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL13379298A 1997-07-11 1998-07-10 Preparation of oxymorphone, oxycodone and derivatives IL133792A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/893,464 US5869669A (en) 1996-07-26 1997-07-11 Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates
PCT/US1998/013592 WO1999002529A1 (en) 1997-07-11 1998-07-10 Preparation of oxymorphone, oxycodone and derivatives

Publications (1)

Publication Number Publication Date
IL133792A0 true IL133792A0 (en) 2001-04-30

Family

ID=25401603

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13379298A IL133792A0 (en) 1997-07-11 1998-07-10 Preparation of oxymorphone, oxycodone and derivatives

Country Status (19)

Country Link
US (7) US5869669A (enEXAMPLES)
EP (1) EP1000065B1 (enEXAMPLES)
JP (1) JP2001518444A (enEXAMPLES)
KR (1) KR100363486B1 (enEXAMPLES)
CN (1) CN1152880C (enEXAMPLES)
AT (1) ATE291023T1 (enEXAMPLES)
AU (1) AU740822B2 (enEXAMPLES)
CA (1) CA2296035C (enEXAMPLES)
DE (1) DE69829379D1 (enEXAMPLES)
HU (1) HUP0003918A3 (enEXAMPLES)
IL (1) IL133792A0 (enEXAMPLES)
IN (1) IN1998KO01500A (enEXAMPLES)
NO (1) NO20000111L (enEXAMPLES)
RU (1) RU2183636C2 (enEXAMPLES)
SK (1) SK102000A3 (enEXAMPLES)
TR (1) TR200000033T2 (enEXAMPLES)
TW (1) TW505648B (enEXAMPLES)
WO (1) WO1999002529A1 (enEXAMPLES)
ZA (1) ZA986144B (enEXAMPLES)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
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US7435817B2 (en) * 2001-08-23 2008-10-14 N.V. Organon C-14 oxidation of morphine derivatives
JP3961796B2 (ja) * 2001-08-27 2007-08-22 ソニー株式会社 情報提供システム、情報処理装置および方法、情報提供装置および方法、記録媒体、並びにプログラム
DE10161963A1 (de) * 2001-12-17 2003-07-03 Johannes Schuetz 6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
US20040058946A1 (en) * 2002-07-05 2004-03-25 Buchwald Stephen L. Abuse-resistant prodrugs of oxycodone and other pharmaceuticals
RU2236412C2 (ru) * 2002-07-18 2004-09-20 Власов Михаил Иванович Способ получения производных морфинона, способ получения производных 14-гидроксиморфинона, и способ получения производных оксиморфона
RU2215741C1 (ru) * 2002-11-05 2003-11-10 Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" Сложные эфиры n-замещенных 14-гидроксиморфинанов и способ их получения
RU2215742C1 (ru) * 2002-11-05 2003-11-10 Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" Способ получения сложных эфиров n-замещенных 14-гидроксиморфинанов
AU2003290630B2 (en) * 2002-11-08 2009-01-29 SpecGx LLC Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
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US6864370B1 (en) 2003-06-05 2005-03-08 Zhaiwei Lin Process for manufacturing oxycodone
US6790959B1 (en) 2003-06-05 2004-09-14 Halsey Drug Company, Inc. Process for manufacturing thebaine
PT1664061T (pt) 2003-09-22 2017-06-22 Glaxosmithkline Australia Pty Ltd Processo para a síntese de compostos de morfinano e seus intermediários
US7875718B2 (en) * 2003-09-22 2011-01-25 Johnson Matthey Public Limited Company Process for the synthesis of morphinane compounds and intermediates thereof
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PL3559010T3 (pl) 2016-12-23 2022-11-21 Minoryx Therapeutics S.L. Sposób wytwarzania 5-[[4-[2-[5-(1-hydroksyetylo)-2-pirydynylo]etoksy]fenylo]metylo]-2,4-tiazolidynodionu i jego soli
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CN110054656B (zh) * 2019-05-28 2021-02-02 宜昌人福药业有限责任公司 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法
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JP2023515918A (ja) 2020-01-13 2023-04-17 デュレクト コーポレーション 不純物が低減された徐放性薬物送達システム及び関連の方法
CN114621239A (zh) * 2020-12-10 2022-06-14 鲁南制药集团股份有限公司 一种纳曲酮的制备方法
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US4795813A (en) * 1981-08-17 1989-01-03 The Florida Board Of Regents On Behalf Of The Florida State University Synthesis of derivatives of codeine and other 3-O-alkylmorphines
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Also Published As

Publication number Publication date
NO20000111D0 (no) 2000-01-10
RU2183636C2 (ru) 2002-06-20
US5922876A (en) 1999-07-13
AU8379198A (en) 1999-02-08
HK1028025A1 (en) 2001-02-02
TR200000033T2 (tr) 2000-12-21
US6013796A (en) 2000-01-11
ATE291023T1 (de) 2005-04-15
KR20010021693A (ko) 2001-03-15
KR100363486B1 (ko) 2002-12-16
US5952495A (en) 1999-09-14
TW505648B (en) 2002-10-11
JP2001518444A (ja) 2001-10-16
EP1000065A4 (en) 2001-09-12
US6008354A (en) 1999-12-28
DE69829379D1 (de) 2005-04-21
ZA986144B (en) 1999-05-19
AU740822B2 (en) 2001-11-15
WO1999002529A1 (en) 1999-01-21
IN1998KO01500A (enEXAMPLES) 2005-03-11
US5869669A (en) 1999-02-09
US5948788A (en) 1999-09-07
HUP0003918A3 (en) 2003-04-28
HUP0003918A2 (hu) 2001-07-30
EP1000065B1 (en) 2005-03-16
CA2296035A1 (en) 1999-01-21
SK102000A3 (en) 2000-07-11
CN1272845A (zh) 2000-11-08
CN1152880C (zh) 2004-06-09
CA2296035C (en) 2004-04-13
NO20000111L (no) 2000-02-25
US6008355A (en) 1999-12-28
EP1000065A1 (en) 2000-05-17

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