ZA986144B - Preparation of 14-hydroxynormorphinones oxycodone noroxymorphone oxymorphone and naltrexone from normorphinones - Google Patents

Preparation of 14-hydroxynormorphinones oxycodone noroxymorphone oxymorphone and naltrexone from normorphinones

Info

Publication number
ZA986144B
ZA986144B ZA986144A ZA986144A ZA986144B ZA 986144 B ZA986144 B ZA 986144B ZA 986144 A ZA986144 A ZA 986144A ZA 986144 A ZA986144 A ZA 986144A ZA 986144 B ZA986144 B ZA 986144B
Authority
ZA
South Africa
Prior art keywords
noroxymorphone
naltrexone
hydroxynormorphinones
normorphinones
oxymorphone
Prior art date
Application number
ZA986144A
Other languages
English (en)
Inventor
Bao-Shan Huang
Yansong Lu
Ben-Yi Ji
Aris Christodoulou
Original Assignee
Penick Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25401603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA986144(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Penick Corp filed Critical Penick Corp
Priority to ZA986144A priority Critical patent/ZA986144B/xx
Publication of ZA986144B publication Critical patent/ZA986144B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA986144A 1997-07-11 1998-07-10 Preparation of 14-hydroxynormorphinones oxycodone noroxymorphone oxymorphone and naltrexone from normorphinones ZA986144B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ZA986144A ZA986144B (en) 1997-07-11 1998-07-10 Preparation of 14-hydroxynormorphinones oxycodone noroxymorphone oxymorphone and naltrexone from normorphinones

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/893,464 US5869669A (en) 1996-07-26 1997-07-11 Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates
ZA986144A ZA986144B (en) 1997-07-11 1998-07-10 Preparation of 14-hydroxynormorphinones oxycodone noroxymorphone oxymorphone and naltrexone from normorphinones

Publications (1)

Publication Number Publication Date
ZA986144B true ZA986144B (en) 1999-05-19

Family

ID=25401603

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA986144A ZA986144B (en) 1997-07-11 1998-07-10 Preparation of 14-hydroxynormorphinones oxycodone noroxymorphone oxymorphone and naltrexone from normorphinones

Country Status (20)

Country Link
US (7) US5869669A (xx)
EP (1) EP1000065B1 (xx)
JP (1) JP2001518444A (xx)
KR (1) KR100363486B1 (xx)
CN (1) CN1152880C (xx)
AT (1) ATE291023T1 (xx)
AU (1) AU740822B2 (xx)
CA (1) CA2296035C (xx)
DE (1) DE69829379D1 (xx)
HK (1) HK1028025A1 (xx)
HU (1) HUP0003918A3 (xx)
IL (1) IL133792A0 (xx)
IN (1) IN1998KO01500A (xx)
NO (1) NO20000111L (xx)
RU (1) RU2183636C2 (xx)
SK (1) SK102000A3 (xx)
TR (1) TR200000033T2 (xx)
TW (1) TW505648B (xx)
WO (1) WO1999002529A1 (xx)
ZA (1) ZA986144B (xx)

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Also Published As

Publication number Publication date
IN1998KO01500A (xx) 2005-03-11
KR100363486B1 (ko) 2002-12-16
NO20000111L (no) 2000-02-25
HUP0003918A2 (hu) 2001-07-30
CN1152880C (zh) 2004-06-09
WO1999002529A1 (en) 1999-01-21
SK102000A3 (en) 2000-07-11
EP1000065A1 (en) 2000-05-17
IL133792A0 (en) 2001-04-30
DE69829379D1 (de) 2005-04-21
US6008354A (en) 1999-12-28
TR200000033T2 (tr) 2000-12-21
NO20000111D0 (no) 2000-01-10
AU8379198A (en) 1999-02-08
KR20010021693A (ko) 2001-03-15
US5952495A (en) 1999-09-14
CA2296035C (en) 2004-04-13
US6013796A (en) 2000-01-11
HUP0003918A3 (en) 2003-04-28
EP1000065B1 (en) 2005-03-16
CA2296035A1 (en) 1999-01-21
US5948788A (en) 1999-09-07
JP2001518444A (ja) 2001-10-16
ATE291023T1 (de) 2005-04-15
RU2183636C2 (ru) 2002-06-20
HK1028025A1 (en) 2001-02-02
TW505648B (en) 2002-10-11
US6008355A (en) 1999-12-28
US5922876A (en) 1999-07-13
US5869669A (en) 1999-02-09
AU740822B2 (en) 2001-11-15
EP1000065A4 (en) 2001-09-12
CN1272845A (zh) 2000-11-08

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