IN1998KO01500A - - Google Patents

Info

Publication number
IN1998KO01500A
IN1998KO01500A IN1500KO1998A IN1998KO01500A IN 1998KO01500 A IN1998KO01500 A IN 1998KO01500A IN 1500KO1998 A IN1500KO1998 A IN 1500KO1998A IN 1998KO01500 A IN1998KO01500 A IN 1998KO01500A
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Bao-Shan Huang
Aris Christodoulou
Yansong Lu
Ben-Yi Ji
Original Assignee
Penick Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25401603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN1998KO01500(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Penick Corp filed Critical Penick Corp
Publication of IN1998KO01500A publication Critical patent/IN1998KO01500A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IN1500KO1998 1997-07-11 1998-08-21 IN1998KO01500A (enEXAMPLES)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/893,464 US5869669A (en) 1996-07-26 1997-07-11 Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates

Publications (1)

Publication Number Publication Date
IN1998KO01500A true IN1998KO01500A (enEXAMPLES) 2005-03-11

Family

ID=25401603

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1500KO1998 IN1998KO01500A (enEXAMPLES) 1997-07-11 1998-08-21

Country Status (19)

Country Link
US (7) US5869669A (enEXAMPLES)
EP (1) EP1000065B1 (enEXAMPLES)
JP (1) JP2001518444A (enEXAMPLES)
KR (1) KR100363486B1 (enEXAMPLES)
CN (1) CN1152880C (enEXAMPLES)
AT (1) ATE291023T1 (enEXAMPLES)
AU (1) AU740822B2 (enEXAMPLES)
CA (1) CA2296035C (enEXAMPLES)
DE (1) DE69829379D1 (enEXAMPLES)
HU (1) HUP0003918A3 (enEXAMPLES)
IL (1) IL133792A0 (enEXAMPLES)
IN (1) IN1998KO01500A (enEXAMPLES)
NO (1) NO20000111L (enEXAMPLES)
RU (1) RU2183636C2 (enEXAMPLES)
SK (1) SK102000A3 (enEXAMPLES)
TR (1) TR200000033T2 (enEXAMPLES)
TW (1) TW505648B (enEXAMPLES)
WO (1) WO1999002529A1 (enEXAMPLES)
ZA (1) ZA986144B (enEXAMPLES)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
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DE10161963A1 (de) * 2001-12-17 2003-07-03 Johannes Schuetz 6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
US7771707B2 (en) 2004-06-12 2010-08-10 Collegium Pharmaceutical, Inc. Abuse-deterrent drug formulations
US20040058946A1 (en) * 2002-07-05 2004-03-25 Buchwald Stephen L. Abuse-resistant prodrugs of oxycodone and other pharmaceuticals
RU2236412C2 (ru) * 2002-07-18 2004-09-20 Власов Михаил Иванович Способ получения производных морфинона, способ получения производных 14-гидроксиморфинона, и способ получения производных оксиморфона
RU2215742C1 (ru) * 2002-11-05 2003-11-10 Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" Способ получения сложных эфиров n-замещенных 14-гидроксиморфинанов
RU2215741C1 (ru) * 2002-11-05 2003-11-10 Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" Сложные эфиры n-замещенных 14-гидроксиморфинанов и способ их получения
ES2332453T3 (es) * 2002-11-08 2010-02-05 Mallinckrodt Inc. Proceso para la preparacion de sales de n-alquilo cuaternario de alcaloides de morfinano.
AU2003299659A1 (en) 2002-12-13 2004-07-09 Durect Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
US6864370B1 (en) 2003-06-05 2005-03-08 Zhaiwei Lin Process for manufacturing oxycodone
US6790959B1 (en) 2003-06-05 2004-09-14 Halsey Drug Company, Inc. Process for manufacturing thebaine
US7875718B2 (en) * 2003-09-22 2011-01-25 Johnson Matthey Public Limited Company Process for the synthesis of morphinane compounds and intermediates thereof
PT1664061T (pt) 2003-09-22 2017-06-22 Glaxosmithkline Australia Pty Ltd Processo para a síntese de compostos de morfinano e seus intermediários
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TW201509943A (zh) 2004-03-30 2015-03-16 Euro Celtique Sa 含有小於25ppm14-羥可待因酮之羥可酮鹽酸鹽之組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝
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US6946556B1 (en) * 2004-05-21 2005-09-20 Acura Pharmaceuticals, Inc. Preparation of opioid analgesics by a one-pot process
CA2569758A1 (en) * 2004-06-08 2005-12-29 Mallinckrodt Inc. Extraction of alkaloids from opium
ES2496765T3 (es) 2004-09-17 2014-09-19 Durect Corporation Composición anestésica local prolongada que contiene SAIB
GB0421149D0 (en) * 2004-09-23 2004-10-27 Johnson Matthey Plc Preparation of oxycodone
GB0421687D0 (en) 2004-09-30 2004-11-03 Johnson Matthey Plc Preparation of opiate analgesics
WO2006084389A1 (de) * 2005-02-11 2006-08-17 Cilag Ltd. Verfahren zur reinigung von noroxymorphon-verbindungen
EP2112153B1 (en) * 2005-03-04 2010-11-10 Euro-Celtique S.A. Method of reducing alpha, beta- unsaturated ketones in opioid compositions
CN101155814B (zh) * 2005-04-06 2010-06-16 东丽株式会社 吗啡喃衍生物的晶体及其制备方法
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
WO2006138020A2 (en) * 2005-06-16 2006-12-28 Mallinckrodt Inc. A synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US20070117826A1 (en) * 2005-11-23 2007-05-24 Forest Laboratories, Inc. Pharmaceutical formulations comprising ibuprofen, oxycodone, and 14-hydroxycodeinone
AU2007224221B2 (en) 2006-03-02 2013-02-14 SpecGx LLC Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
CA2663909A1 (en) * 2006-09-20 2008-03-27 Mallinckrodt Inc. Preparation of substituted morphinan-6-ones and salts and intermediates thereof
US8134002B2 (en) 2006-10-17 2012-03-13 Penick Corporation Process for preparing oxymorphone
AU2012216358B2 (en) * 2006-10-17 2014-11-20 Penick Corporation Process For Preparing Oxymorphone, Naltrexone and Buprenorphine
US20080125592A1 (en) * 2006-10-17 2008-05-29 Penick Corporation Process for preparing oxymorphone, naltrexone, and buprenorphine
CA2674915C (en) * 2006-10-17 2015-06-30 Penick Corporation Process for preparing oxymorphone
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CN104761561A (zh) * 2006-12-04 2015-07-08 诺拉姆科有限公司 减少羟考酮碱中杂质的方法
CN101652370A (zh) * 2006-12-04 2010-02-17 诺拉姆科有限公司 制备14-羟基可待因酮水平减少的羟考酮的方法
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EP2137190B1 (en) * 2007-04-16 2013-06-12 Mallinckrodt LLC Novel opiate reduction utilizing catalytic hydrogen transfer reaction
US20090018154A1 (en) * 2007-05-17 2009-01-15 Endo Pharmaceuticals, Inc., A Corporation Of Delaware Opioid and methods of making and using the same
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EP2222643B1 (en) * 2007-12-17 2019-03-20 SpecGx LLC Sinomenine derivatives and processes for their synthesis
NZ586194A (en) * 2007-12-17 2012-07-27 Mallinckrodt Llc Processes for the production of (+)-'nal' morphinan compounds
WO2009111162A1 (en) * 2008-02-29 2009-09-11 Mallinckrodt Inc. Process for the preparation of 3-hydroxymorphinan derivatives
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CA2726220C (en) * 2008-05-27 2017-03-28 Mallinckrodt Inc. Processes and compounds for the preparation of normorphinans
US9458109B2 (en) 2008-09-03 2016-10-04 Mallinckrodt Llc Substituted berbines and processes for their synthesis
AU2009300379B2 (en) * 2008-09-30 2015-04-02 SpecGx LLC Processes for the alkylation of secondary amine groups of morphinan derivatives
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
UA102916C2 (uk) 2009-07-02 2013-08-27 Кемфарм, Інк. Композиція на основі кон'югату гідрокодону з бензойною кислотою, похідними бензойної кислоти або гетероарилкарбоновою кислотою, проліки, спосіб лікування від зловживань
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
JP2013529595A (ja) 2010-06-11 2013-07-22 ローズ テクノロジーズ 第3級アミンのn−脱アルキル化方法
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ES2701855T3 (es) 2016-05-31 2019-02-26 Alcaliber Investig Desarrollo E Innovacion Slu Proceso para la obtención de 3,14-diacetiloximorfona a partir de oripavina
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JP7294661B2 (ja) 2016-12-23 2023-06-20 ミノリックス セラピューティクス エセ.エレ. 5-[[4-[2-[5-(1-ヒドロキシエチル)-2-ピリジニル]エトキシ]フェニル]メチル]-2,4-チアゾリジンジオンおよびその塩を調製するためのプロセス
SK592017A3 (sk) 2017-07-04 2019-01-08 Saneca Pharmaceuticals A. S. Spôsob prípravy morfínanových zlúčenín
CN111836813A (zh) 2018-02-23 2020-10-27 罗德科技公司 新型阿片样化合物及其用途
CN110054656B (zh) * 2019-05-28 2021-02-02 宜昌人福药业有限责任公司 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法
WO2021007366A1 (en) * 2019-07-08 2021-01-14 St. Louis College Of Pharmacy G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment
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CN114621239A (zh) * 2020-12-10 2022-06-14 鲁南制药集团股份有限公司 一种纳曲酮的制备方法
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US4795813A (en) * 1981-08-17 1989-01-03 The Florida Board Of Regents On Behalf Of The Florida State University Synthesis of derivatives of codeine and other 3-O-alkylmorphines
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Also Published As

Publication number Publication date
AU740822B2 (en) 2001-11-15
CN1272845A (zh) 2000-11-08
RU2183636C2 (ru) 2002-06-20
US6013796A (en) 2000-01-11
EP1000065B1 (en) 2005-03-16
AU8379198A (en) 1999-02-08
EP1000065A1 (en) 2000-05-17
HK1028025A1 (en) 2001-02-02
NO20000111L (no) 2000-02-25
ZA986144B (en) 1999-05-19
KR100363486B1 (ko) 2002-12-16
US6008355A (en) 1999-12-28
TR200000033T2 (tr) 2000-12-21
KR20010021693A (ko) 2001-03-15
CA2296035A1 (en) 1999-01-21
US6008354A (en) 1999-12-28
HUP0003918A3 (en) 2003-04-28
US5922876A (en) 1999-07-13
ATE291023T1 (de) 2005-04-15
JP2001518444A (ja) 2001-10-16
TW505648B (en) 2002-10-11
WO1999002529A1 (en) 1999-01-21
CA2296035C (en) 2004-04-13
NO20000111D0 (no) 2000-01-10
EP1000065A4 (en) 2001-09-12
SK102000A3 (en) 2000-07-11
DE69829379D1 (de) 2005-04-21
US5869669A (en) 1999-02-09
HUP0003918A2 (hu) 2001-07-30
CN1152880C (zh) 2004-06-09
IL133792A0 (en) 2001-04-30
US5948788A (en) 1999-09-07
US5952495A (en) 1999-09-14

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