IL133056A0 - A polypeptide containing an immunogenic portion of a m tuberculosis antigen a variant thereof pharmaceutical compositions vaccines and kits containing same - Google Patents

A polypeptide containing an immunogenic portion of a m tuberculosis antigen a variant thereof pharmaceutical compositions vaccines and kits containing same

Info

Publication number
IL133056A0
IL133056A0 IL13305698A IL13305698A IL133056A0 IL 133056 A0 IL133056 A0 IL 133056A0 IL 13305698 A IL13305698 A IL 13305698A IL 13305698 A IL13305698 A IL 13305698A IL 133056 A0 IL133056 A0 IL 133056A0
Authority
IL
Israel
Prior art keywords
sequences
polypeptide
antigen
dna
variant
Prior art date
Application number
IL13305698A
Other languages
English (en)
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of IL133056A0 publication Critical patent/IL133056A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL13305698A 1997-05-20 1998-05-20 A polypeptide containing an immunogenic portion of a m tuberculosis antigen a variant thereof pharmaceutical compositions vaccines and kits containing same IL133056A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85938197A 1997-05-20 1997-05-20
US09/073,010 US6613881B1 (en) 1997-05-20 1998-05-05 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
PCT/US1998/010407 WO1998053075A2 (en) 1997-05-20 1998-05-20 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use

Publications (1)

Publication Number Publication Date
IL133056A0 true IL133056A0 (en) 2001-03-19

Family

ID=26754016

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13305698A IL133056A0 (en) 1997-05-20 1998-05-20 A polypeptide containing an immunogenic portion of a m tuberculosis antigen a variant thereof pharmaceutical compositions vaccines and kits containing same
IL133056A IL133056A (en) 1997-05-20 1999-11-19 Polypeptide containing an immunogenic portion of an m. tuberculosis antigen, a variant thereof and pharmaceutical compositions containing same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL133056A IL133056A (en) 1997-05-20 1999-11-19 Polypeptide containing an immunogenic portion of an m. tuberculosis antigen, a variant thereof and pharmaceutical compositions containing same

Country Status (20)

Country Link
US (1) US6613881B1 (enExample)
EP (4) EP2270170B1 (enExample)
JP (4) JP4162155B2 (enExample)
KR (4) KR100652513B1 (enExample)
AT (1) ATE420180T1 (enExample)
AU (1) AU742751B2 (enExample)
BR (1) BR9809445A (enExample)
CA (2) CA2290774A1 (enExample)
CZ (2) CZ300866B6 (enExample)
DE (1) DE69840449D1 (enExample)
DK (1) DK1012293T3 (enExample)
ES (1) ES2321039T3 (enExample)
HU (1) HU226520B1 (enExample)
IL (2) IL133056A0 (enExample)
NO (4) NO324880B1 (enExample)
NZ (1) NZ501310A (enExample)
PL (1) PL191121B1 (enExample)
PT (1) PT1012293E (enExample)
TR (1) TR200000115T2 (enExample)
WO (1) WO1998053075A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
ATE432348T1 (de) 1997-06-06 2009-06-15 Univ California Inhibitoren von immunstimulatorischen dna sequenz aktivität
CA2319380A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from m. tuberculosis
CA2348475A1 (en) * 1998-11-04 2000-05-11 Isis Innovation Limited Tuberculosis diagnostic test
US20030027774A1 (en) * 1999-03-18 2003-02-06 Ronald C. Hendrickson Tuberculosis antigens and methods of use therefor
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
EP1200466A2 (en) * 1999-07-13 2002-05-02 Statens Serum Institut Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosisesat-6 gene family
JP2003510370A (ja) 1999-10-07 2003-03-18 コリクサ コーポレイション Mycobacteriumtuberculosisの融合タンパク質
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
AU2001241738A1 (en) 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
WO2001079274A2 (en) * 2000-04-19 2001-10-25 Statens Serum Institut Tuberculosis antigens and methods of use thereof
EP1542732B1 (en) 2000-06-20 2009-09-16 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
WO2003070187A2 (en) * 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
JP4838259B2 (ja) * 2004-11-16 2011-12-14 クルセル ホランド ベー ヴェー 組み換えウイルスベクターを含む多価ワクチン
EP1904848A2 (en) * 2005-04-29 2008-04-02 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
WO2007005627A2 (en) 2005-07-01 2007-01-11 Forsyth Dental Infirmary For Children Tuberculosis antigen detection assays and vaccines
US20070081944A1 (en) * 2005-09-30 2007-04-12 Reed Steven G Iontophoresis apparatus and method for the diagnosis of tuberculosis
EP2397855A3 (en) 2006-03-14 2012-03-14 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection
NO2315597T3 (enExample) 2008-07-25 2018-01-20
DK2315773T3 (en) 2008-07-25 2016-12-12 Glaxosmithkline Biologicals Sa Polypeptides, polynucleotides and compositions for use in the treatment of latent tuberculosis
SI2315834T1 (sl) 2008-07-25 2018-09-28 Glaxosmithkline Biologicals S.A. Tuberkulozni Rv2386c protein, sestavki in njegove uporabe
WO2011092253A1 (en) 2010-01-27 2011-08-04 Glaxosmithkline Biologicals S.A. Modified tuberculosis antigens
GB201012072D0 (en) * 2010-07-19 2010-09-01 Sec Dep For Environment Food A Diagnostic reagents
EP2721140B1 (en) 2011-06-19 2016-11-23 Abogen, Inc. Devices, solutions and methods for sample collection
CN107430105A (zh) * 2015-02-09 2017-12-01 阿波根有限公司 用于采集相关应用、分析和诊断的样本的设备、溶液和方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4879213A (en) 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4952395A (en) 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
US5330754A (en) 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
JPH09510866A (ja) * 1993-12-23 1997-11-04 アグリサーチ ニュージーランド パストラル アグリカルチャー リサーチ インスティテュート,リミテッド ミコバクテリア毒力因子およびその同定のための方法
IE960132A1 (en) * 1995-03-13 1996-09-18 Astra Ab New DNA molecules
BR9610262B1 (pt) 1995-09-01 2013-11-26 Compostos e métodos para a imunoterapia e diagnose de tuberculose.
PT2154248E (pt) 1995-09-01 2012-01-16 Corixa Corp Compostos e métodos para diagnóstico de tuberculose
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
TR199901569T2 (xx) * 1996-10-11 2000-12-21 Corixa Corporation T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.

Also Published As

Publication number Publication date
EP2270170A1 (en) 2011-01-05
EP1012293A2 (en) 2000-06-28
JP4162155B2 (ja) 2008-10-08
BR9809445A (pt) 2000-06-13
CA2783134A1 (en) 1998-11-26
KR20060066139A (ko) 2006-06-15
JP2002514084A (ja) 2002-05-14
PL337330A1 (en) 2000-08-14
NO995689D0 (no) 1999-11-19
KR100893118B1 (ko) 2009-04-14
KR100652513B1 (ko) 2006-12-01
EP1012293B1 (en) 2009-01-07
JP4759010B2 (ja) 2011-08-31
KR100924475B1 (ko) 2009-11-03
NO20075901L (no) 2000-01-18
JP2008283961A (ja) 2008-11-27
JP4764445B2 (ja) 2011-09-07
EP2172551A3 (en) 2010-11-10
WO1998053075A2 (en) 1998-11-26
DK1012293T3 (da) 2009-05-04
PT1012293E (pt) 2009-04-08
ATE420180T1 (de) 2009-01-15
CZ300866B6 (cs) 2009-08-26
DE69840449D1 (de) 2009-02-26
EP2248900B1 (en) 2012-07-18
US6613881B1 (en) 2003-09-02
EP2172551A2 (en) 2010-04-07
AU742751B2 (en) 2002-01-10
JP2008245644A (ja) 2008-10-16
NO20075900L (no) 2000-01-18
KR20080036663A (ko) 2008-04-28
AU7690798A (en) 1998-12-11
CZ410099A3 (cs) 2000-05-17
NO20075902L (no) 2000-01-18
NZ501310A (en) 2001-09-28
IL133056A (en) 2010-11-30
CA2290774A1 (en) 1998-11-26
JP4759011B2 (ja) 2011-08-31
HUP0003402A2 (hu) 2000-12-28
ES2321039T3 (es) 2009-06-01
HU226520B1 (en) 2009-03-30
EP2270170B1 (en) 2013-11-06
NO324880B1 (no) 2007-12-27
CZ303194B6 (cs) 2012-05-23
HUP0003402A3 (en) 2001-03-28
TR200000115T2 (tr) 2000-11-21
NO995689L (no) 2000-01-18
PL191121B1 (pl) 2006-03-31
WO1998053075A3 (en) 1999-04-01
KR20070026886A (ko) 2007-03-08
KR20010012812A (ko) 2001-02-26
JP2008253260A (ja) 2008-10-23
KR100909640B1 (ko) 2009-07-27
EP2248900A1 (en) 2010-11-10

Similar Documents

Publication Publication Date Title
IL133056A0 (en) A polypeptide containing an immunogenic portion of a m tuberculosis antigen a variant thereof pharmaceutical compositions vaccines and kits containing same
WO1996040915A3 (en) Novel ctla4/cd28 ligands and uses therefor
CA2230885A1 (en) Compounds and methods for immunotherapy and diagnosis of tuberculosis
NZ502391A (en) Mammalian cytokine: interleukin-B30 and related reagents
CA2263889A1 (en) P-selectin ligand proteins
EP0784059A4 (en) ANTIGENIC POLYPEPTIDE OF CHLAMYDIA PNEUMONIAE
CA2337100A1 (en) Polypeptides of lymphodendritic cell adhesion molecules (ldcams) and polynucleotides encoding the same
AU2759895A (en) Recombinant allergen, fragments thereof, corresponding recombinant dna molecules, vectors and hosts containing the dna molecules, diagnostic and therapeutic uses of said allergens and fragments
DE3686579D1 (en) Prokaryotisches expressionssystem.
AU5776799A (en) Modified hcv peptide vaccines
EP0805204A3 (de) Nebenhoden-spezifisches Rezeptorprotein und dessen Verwendung
EP1277837A3 (de) Epididymis-spezifische DNA-Sequenzen und deren Verwendung
SE9704141D0 (sv) New protein and nucleotide sequence, encoding said protein
KR930701603A (ko) 재조합 47 및 31 킬로달톤 코코아 단백질 및 그의 전구체
WO1995008628A3 (en) Nucleic acids encoding merosin, merosin fragments and uses thereof
WO2003097814A3 (en) Scytovirins and related conjugates, fusion proteins, nucleic acids, vectors, host cells, compositions, antibodies and methods of using scytovirins
WO1990007000A3 (en) Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
PE20010239A1 (es) Gen derivado de lawsonia y polipeptidos, peptidos y proteinas de hemolisina relacionados y sus usos
EP0897984A3 (en) D-Sorbitol dehydrogenase gene
DE60033583D1 (de) Eine mycobacterium tuberculosis kodierende sequenz zur expression von heterologen proteinen
WO1999043834A3 (en) P-selectin ligand protein, including tetrameric fusion proteins
WO1997031104A3 (en) Candida albicans profilin gene
CA2323506A1 (en) Mammalian blood loss-induced gene, kd312
WO2001046412A3 (de) Interaktionsprotein für stat transkriptionsfaktor
NZ511303A (en) Secreted and transmembrane polypeptides and nucleic acids encoding the same with homology to Hep27 protein