BR9809445A - Polipeptìdeo compreendendo uma porção imunogênica de um antìgeno de m. tubercolosis, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica, vacina, proteìna de fusão, processos para indução de imunidade protetora em um paciente, processo de detecção de tuberculose em um paciente,e , kit de diagnóstico. - Google Patents

Polipeptìdeo compreendendo uma porção imunogênica de um antìgeno de m. tubercolosis, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica, vacina, proteìna de fusão, processos para indução de imunidade protetora em um paciente, processo de detecção de tuberculose em um paciente,e , kit de diagnóstico.

Info

Publication number
BR9809445A
BR9809445A BR9809445-9A BR9809445A BR9809445A BR 9809445 A BR9809445 A BR 9809445A BR 9809445 A BR9809445 A BR 9809445A BR 9809445 A BR9809445 A BR 9809445A
Authority
BR
Brazil
Prior art keywords
patient
tuberculosis
immunogenic portion
vaccine
antigen
Prior art date
Application number
BR9809445-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Mark R Alderson
Davion C Dillon
Yasir A W Skeiky
Antonio Campos-Neto
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of BR9809445A publication Critical patent/BR9809445A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR9809445-9A 1997-05-20 1998-05-20 Polipeptìdeo compreendendo uma porção imunogênica de um antìgeno de m. tubercolosis, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica, vacina, proteìna de fusão, processos para indução de imunidade protetora em um paciente, processo de detecção de tuberculose em um paciente,e , kit de diagnóstico. BR9809445A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85938197A 1997-05-20 1997-05-20
US09/073,010 US6613881B1 (en) 1997-05-20 1998-05-05 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
PCT/US1998/010407 WO1998053075A2 (en) 1997-05-20 1998-05-20 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use

Publications (1)

Publication Number Publication Date
BR9809445A true BR9809445A (pt) 2000-06-13

Family

ID=26754016

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809445-9A BR9809445A (pt) 1997-05-20 1998-05-20 Polipeptìdeo compreendendo uma porção imunogênica de um antìgeno de m. tubercolosis, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica, vacina, proteìna de fusão, processos para indução de imunidade protetora em um paciente, processo de detecção de tuberculose em um paciente,e , kit de diagnóstico.

Country Status (20)

Country Link
US (1) US6613881B1 (enExample)
EP (4) EP1012293B1 (enExample)
JP (4) JP4162155B2 (enExample)
KR (4) KR100652513B1 (enExample)
AT (1) ATE420180T1 (enExample)
AU (1) AU742751B2 (enExample)
BR (1) BR9809445A (enExample)
CA (2) CA2783134A1 (enExample)
CZ (2) CZ303194B6 (enExample)
DE (1) DE69840449D1 (enExample)
DK (1) DK1012293T3 (enExample)
ES (1) ES2321039T3 (enExample)
HU (1) HU226520B1 (enExample)
IL (2) IL133056A0 (enExample)
NO (4) NO324880B1 (enExample)
NZ (1) NZ501310A (enExample)
PL (1) PL191121B1 (enExample)
PT (1) PT1012293E (enExample)
TR (1) TR200000115T2 (enExample)
WO (1) WO1998053075A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
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US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
ATE432348T1 (de) * 1997-06-06 2009-06-15 Univ California Inhibitoren von immunstimulatorischen dna sequenz aktivität
NZ504951A (en) * 1997-11-10 2001-06-29 Statens Seruminstitut Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
DE69941545D1 (de) 1998-11-04 2009-11-26 Isis Innovation Tuberkulose diagnose test
US20030027774A1 (en) * 1999-03-18 2003-02-06 Ronald C. Hendrickson Tuberculosis antigens and methods of use therefor
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
JP5010079B2 (ja) 1999-07-13 2012-08-29 スタテンズ セーラム インスティテュート マイコバクテリウム・ツベルクローシスｅｓａｔ−６遺伝子ファミリーベースの結核ワクチン及び診断法
CA2386841A1 (en) 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
WO2001062893A2 (en) 2000-02-25 2001-08-30 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
AU2001250294A1 (en) * 2000-04-19 2001-10-30 Statens Serum Institut Tuberculosis antigens and methods of use thereof
AU6867801A (en) * 2000-06-20 2002-01-02 Corixa Corp Fusion proteins of mycobacterium tuberculosis
WO2003070187A2 (en) * 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
KR101255870B1 (ko) * 2004-11-16 2013-04-17 아에라스 글로벌 티비 백신 파운데이션 재조합 바이러스 벡터를 포함하는 다가 백신
US8475803B2 (en) 2005-04-29 2013-07-02 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
WO2007005627A2 (en) 2005-07-01 2007-01-11 Forsyth Dental Infirmary For Children Tuberculosis antigen detection assays and vaccines
US20070081944A1 (en) * 2005-09-30 2007-04-12 Reed Steven G Iontophoresis apparatus and method for the diagnosis of tuberculosis
US8053181B2 (en) 2006-03-14 2011-11-08 Oregon Health & Science University Methods for detecting a Mycobacterium tuberculosis infection
EP2315834B1 (en) 2008-07-25 2018-06-13 GlaxoSmithKline Biologicals S.A. The tuberculosis rv2386c protein, compositions and uses thereof
NO2315597T3 (enExample) 2008-07-25 2018-01-20
SI2315773T1 (sl) * 2008-07-25 2016-12-30 Glaxosmithkline Biologicals S.A. Polipeptidi, polinukleotidi in sestavki za uporabo pri zdravljenju latentne tuberkuloze
US8932600B2 (en) 2010-01-27 2015-01-13 Glaxosmithkline Biologicals S.A. Modified tuberculosis antigens
GB201012072D0 (en) * 2010-07-19 2010-09-01 Sec Dep For Environment Food A Diagnostic reagents
BR112013032629A2 (pt) 2011-06-19 2017-08-01 Abogen Inc dispositivos, soluções e métodos para coletamento de amostra
CN107430105A (zh) * 2015-02-09 2017-12-01 阿波根有限公司 用于采集相关应用、分析和诊断的样本的设备、溶液和方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4879213A (en) 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US4952395A (en) 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
US5330754A (en) 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
AU1445895A (en) * 1993-12-23 1995-07-10 AgResearch New Zealand Pastoral Agriculture Research Institute, Ltd Mycobacteria virulence factors and a method for their identification
AU706367B2 (en) * 1995-03-13 1999-06-17 Astra Aktiebolag New DNA molecules
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
PT1203817E (pt) 1995-09-01 2006-08-31 Corixa Corp Compostos e metodos para imunoterapia e le diagnostic de tuberculose
DE69636075D1 (de) 1995-09-01 2006-06-01 Corixa Corp Verbindungen und verfahren zur diagnose von tuberkulose
EP0934415A2 (en) * 1996-10-11 1999-08-11 Corixa Corporation Compounds and methods for diagnosis of tuberculosis

Also Published As

Publication number Publication date
TR200000115T2 (tr) 2000-11-21
IL133056A (en) 2010-11-30
EP1012293B1 (en) 2009-01-07
KR100893118B1 (ko) 2009-04-14
CZ300866B6 (cs) 2009-08-26
EP2270170A1 (en) 2011-01-05
EP1012293A2 (en) 2000-06-28
KR20010012812A (ko) 2001-02-26
KR100924475B1 (ko) 2009-11-03
CZ303194B6 (cs) 2012-05-23
KR20080036663A (ko) 2008-04-28
DE69840449D1 (de) 2009-02-26
NO324880B1 (no) 2007-12-27
JP2008283961A (ja) 2008-11-27
PL337330A1 (en) 2000-08-14
EP2248900A1 (en) 2010-11-10
DK1012293T3 (da) 2009-05-04
KR20070026886A (ko) 2007-03-08
CA2783134A1 (en) 1998-11-26
AU7690798A (en) 1998-12-11
EP2172551A3 (en) 2010-11-10
NZ501310A (en) 2001-09-28
JP4759010B2 (ja) 2011-08-31
HUP0003402A2 (hu) 2000-12-28
KR100909640B1 (ko) 2009-07-27
NO995689D0 (no) 1999-11-19
JP2008253260A (ja) 2008-10-23
HU226520B1 (en) 2009-03-30
JP2008245644A (ja) 2008-10-16
NO995689L (no) 2000-01-18
EP2248900B1 (en) 2012-07-18
US6613881B1 (en) 2003-09-02
NO20075901L (no) 2000-01-18
JP4764445B2 (ja) 2011-09-07
NO20075902L (no) 2000-01-18
IL133056A0 (en) 2001-03-19
JP2002514084A (ja) 2002-05-14
CZ410099A3 (cs) 2000-05-17
ES2321039T3 (es) 2009-06-01
NO20075900L (no) 2000-01-18
AU742751B2 (en) 2002-01-10
WO1998053075A2 (en) 1998-11-26
KR100652513B1 (ko) 2006-12-01
EP2270170B1 (en) 2013-11-06
CA2290774A1 (en) 1998-11-26
PL191121B1 (pl) 2006-03-31
JP4162155B2 (ja) 2008-10-08
EP2172551A2 (en) 2010-04-07
WO1998053075A3 (en) 1999-04-01
ATE420180T1 (de) 2009-01-15
PT1012293E (pt) 2009-04-08
KR20060066139A (ko) 2006-06-15
JP4759011B2 (ja) 2011-08-31
HUP0003402A3 (en) 2001-03-28

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]

Free format text: REF. A RPI 1970 DE 07/10/2008, POR HAVER UM ERRO GRAFICO NA FL. 2 DO PARECER TECNICO.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25G Requested change of headquarter approved

Owner name: CORIXA CORPORATION (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020090016086/RJ DE 16/02/2009.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 24, 25, 32 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.