ATE420180T1 - Verbindungen zur immuntherapie und diagnose von tuberkulose und methoden zu deren verwendung - Google Patents

Verbindungen zur immuntherapie und diagnose von tuberkulose und methoden zu deren verwendung

Info

Publication number
ATE420180T1
ATE420180T1 AT98924827T AT98924827T ATE420180T1 AT E420180 T1 ATE420180 T1 AT E420180T1 AT 98924827 T AT98924827 T AT 98924827T AT 98924827 T AT98924827 T AT 98924827T AT E420180 T1 ATE420180 T1 AT E420180T1
Authority
AT
Austria
Prior art keywords
sequences
polypeptide
antigen
dna
given
Prior art date
Application number
AT98924827T
Other languages
English (en)
Inventor
Mark Alderson
Davin Dillon
Yasir Skeiky
Antonio Campos-Neto
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of ATE420180T1 publication Critical patent/ATE420180T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98924827T 1997-05-20 1998-05-20 Verbindungen zur immuntherapie und diagnose von tuberkulose und methoden zu deren verwendung ATE420180T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85938197A 1997-05-20 1997-05-20
US09/073,010 US6613881B1 (en) 1997-05-20 1998-05-05 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
PCT/US1998/010407 WO1998053075A2 (en) 1997-05-20 1998-05-20 Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use

Publications (1)

Publication Number Publication Date
ATE420180T1 true ATE420180T1 (de) 2009-01-15

Family

ID=26754016

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98924827T ATE420180T1 (de) 1997-05-20 1998-05-20 Verbindungen zur immuntherapie und diagnose von tuberkulose und methoden zu deren verwendung

Country Status (20)

Country Link
US (1) US6613881B1 (de)
EP (4) EP2172551A3 (de)
JP (4) JP4162155B2 (de)
KR (4) KR100893118B1 (de)
AT (1) ATE420180T1 (de)
AU (1) AU742751B2 (de)
BR (1) BR9809445A (de)
CA (2) CA2783134A1 (de)
CZ (2) CZ300866B6 (de)
DE (1) DE69840449D1 (de)
DK (1) DK1012293T3 (de)
ES (1) ES2321039T3 (de)
HU (1) HU226520B1 (de)
IL (2) IL133056A0 (de)
NO (4) NO324880B1 (de)
NZ (1) NZ501310A (de)
PL (1) PL191121B1 (de)
PT (1) PT1012293E (de)
TR (1) TR200000115T2 (de)
WO (1) WO1998053075A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US7087713B2 (en) 2000-02-25 2006-08-08 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
DE69840850D1 (de) * 1997-06-06 2009-07-09 Dynavax Tech Corp Inhibitoren von immunstimulatorischen dna sequenz aktivität
NZ504951A (en) * 1997-11-10 2001-06-29 Statens Seruminstitut Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
WO2000026248A2 (en) 1998-11-04 2000-05-11 Isis Innovation Limited Tuberculosis diagnostic test
US20030027774A1 (en) * 1999-03-18 2003-02-06 Ronald C. Hendrickson Tuberculosis antigens and methods of use therefor
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
CA2378763A1 (en) 1999-07-13 2001-01-18 Statens Serum Institut Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosis esat-6 gene family
WO2001024820A1 (en) 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
CA2405247A1 (en) * 2000-04-19 2001-10-25 Statens Serum Institut Tuberculosis antigens and methods of use thereof
EP2133100B1 (de) * 2000-06-20 2011-10-05 Corixa Corporation MTB32A Antigen aus Mycobakterium Tuberculosis mit inaktivierter protease Aktivität und Fusionsproteine die das Antigen enthalten
WO2003070187A2 (en) * 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2005118884A1 (en) * 2004-05-28 2005-12-15 The United States Of America As Represented By The Secretary Of The Navy A method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
CA2586620C (en) * 2004-11-16 2014-06-03 Crucell Holland B.V. Multivalent vaccines comprising recombinant viral vectors
WO2006117538A2 (en) * 2005-04-29 2006-11-09 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
EP2305701A1 (de) 2005-07-01 2011-04-06 Forsyth Dental Infirmary for Children Assays zur Detektion von Tuberkuloseantigenen und Impfstoffe
WO2007041539A1 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies, Inc. Iontophoresis apparatus and method for the diagnosis of tuberculosis
WO2007106560A2 (en) 2006-03-14 2007-09-20 Oregon Health & Science University Methods for detecting a mycobacterium tuberculosis infection
KR20110049834A (ko) 2008-07-25 2011-05-12 글락소스미스클라인 바이오로지칼즈 에스.에이. 투베르쿨로시스 ｒｖ2386ｃ 단백질, 이를 함유하는 조성물 및 이의 용도
LT2315597T (lt) 2008-07-25 2018-02-12 Glaxosmithkline Biologicals S.A. Naujos kompozicijos ir būdai
AU2009273130B2 (en) * 2008-07-25 2014-10-16 Glaxo Group Limited Novel compositions and methods
JP6010463B2 (ja) 2010-01-27 2016-10-19 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変された結核抗原
GB201012072D0 (en) * 2010-07-19 2010-09-01 Sec Dep For Environment Food A Diagnostic reagents
WO2012177656A2 (en) 2011-06-19 2012-12-27 Abogen, Inc. Devices, solutions and methods for sample collection
US12038434B2 (en) 2015-02-09 2024-07-16 DNA Genotek, Inc. Devices, solutions and methods for sample collection related applications, analysis and diagnosis

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4689397A (en) 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4879213A (en) 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US4952395A (en) 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
US5330754A (en) 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
EP0736098A1 (de) * 1993-12-23 1996-10-09 Agresearch New Zealand Pastoral Agriculture Research Institute, Ltd. Mykobakterien virulenz-faktoren und verfahren zur identifizierung
AU706367B2 (en) * 1995-03-13 1999-06-17 Astra Aktiebolag New DNA molecules
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
MX9801687A (es) 1995-09-01 1998-11-29 Corixa Corp Compuestos y metodos para el diagnostico de tuberculosis.
KR100433750B1 (ko) 1995-09-01 2004-09-01 코릭사 코포레이션 마이코박테리움튜베르큘로시스항원을포함하는폴리펩타이드및이를포함하는약제학적조성물
WO1998016645A2 (en) * 1996-10-11 1998-04-23 Corixa Corporation Compounds and methods for diagnosis of tuberculosis

Also Published As

Publication number Publication date
NO995689D0 (no) 1999-11-19
PT1012293E (pt) 2009-04-08
EP1012293B1 (de) 2009-01-07
CA2290774A1 (en) 1998-11-26
EP2248900A1 (de) 2010-11-10
NO20075901L (no) 2000-01-18
EP2172551A2 (de) 2010-04-07
HU226520B1 (en) 2009-03-30
KR100652513B1 (ko) 2006-12-01
EP1012293A2 (de) 2000-06-28
JP4759010B2 (ja) 2011-08-31
EP2172551A3 (de) 2010-11-10
CZ410099A3 (cs) 2000-05-17
PL191121B1 (pl) 2006-03-31
HUP0003402A3 (en) 2001-03-28
IL133056A (en) 2010-11-30
TR200000115T2 (tr) 2000-11-21
KR100909640B1 (ko) 2009-07-27
KR20060066139A (ko) 2006-06-15
NO20075902L (no) 2000-01-18
AU7690798A (en) 1998-12-11
NO20075900L (no) 2000-01-18
NO995689L (no) 2000-01-18
PL337330A1 (en) 2000-08-14
US6613881B1 (en) 2003-09-02
WO1998053075A2 (en) 1998-11-26
EP2270170B1 (de) 2013-11-06
JP2002514084A (ja) 2002-05-14
IL133056A0 (en) 2001-03-19
JP2008253260A (ja) 2008-10-23
CZ300866B6 (cs) 2009-08-26
KR100924475B1 (ko) 2009-11-03
WO1998053075A3 (en) 1999-04-01
JP2008283961A (ja) 2008-11-27
BR9809445A (pt) 2000-06-13
CA2783134A1 (en) 1998-11-26
EP2248900B1 (de) 2012-07-18
CZ303194B6 (cs) 2012-05-23
KR20080036663A (ko) 2008-04-28
ES2321039T3 (es) 2009-06-01
KR20010012812A (ko) 2001-02-26
KR100893118B1 (ko) 2009-04-14
NZ501310A (en) 2001-09-28
NO324880B1 (no) 2007-12-27
HUP0003402A2 (hu) 2000-12-28
JP4759011B2 (ja) 2011-08-31
JP4764445B2 (ja) 2011-09-07
KR20070026886A (ko) 2007-03-08
JP4162155B2 (ja) 2008-10-08
AU742751B2 (en) 2002-01-10
DE69840449D1 (de) 2009-02-26
JP2008245644A (ja) 2008-10-16
DK1012293T3 (da) 2009-05-04
EP2270170A1 (de) 2011-01-05

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